Carlos A. Zarate, M.D. - Publications

Affiliations: 
National Institute of Mental Health, Bethesda, MD, United States 
Area:
Depression, Ketamine

291 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Gilbert JR, Wusinich C, Zarate CA. A Predictive Coding Framework for Understanding Major Depression. Frontiers in Human Neuroscience. 16: 787495. PMID 35308621 DOI: 10.3389/fnhum.2022.787495  0.654
2022 Fountoulakis KN, Tohen M, Zarate CA. Lithium treatment of Bipolar disorder in adults: A systematic review of randomized trials and meta-analyses. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 54: 100-115. PMID 34980362 DOI: 10.1016/j.euroneuro.2021.10.003  0.348
2021 Kheirkhah M, Baumbach P, Leistritz L, Witte OW, Walter M, Gilbert JR, Zarate CA, Klingner CM. The Right Hemisphere Is Responsible for the Greatest Differences in Human Brain Response to High-Arousing Emotional versus Neutral Stimuli: A MEG Study. Brain Sciences. 11. PMID 34439579 DOI: 10.3390/brainsci11080960  0.585
2021 Gilbert JR, Galiano CS, Nugent AC, Zarate CA. Ketamine and Attentional Bias Toward Emotional Faces: Dynamic Causal Modeling of Magnetoencephalographic Connectivity in Treatment-Resistant Depression. Frontiers in Psychiatry. 12: 673159. PMID 34220581 DOI: 10.3389/fpsyt.2021.673159  0.699
2021 Fagerholm ED, Leech R, Williams S, Zarate CA, Moran RJ, Gilbert JR. Fine-tuning neural excitation/inhibition for tailored ketamine use in treatment-resistant depression. Translational Psychiatry. 11: 335. PMID 34052834 DOI: 10.1038/s41398-021-01442-3  0.691
2021 Bahji A, Zarate CA, Vazquez GH. Ketamine for bipolar depression: a systematic review. The International Journal of Neuropsychopharmacology. PMID 33929489 DOI: 10.1093/ijnp/pyab023  0.391
2021 Henter ID, Park LT, Zarate CA. Novel Glutamatergic Modulators for the Treatment of Mood Disorders: Current Status. Cns Drugs. PMID 33904154 DOI: 10.1007/s40263-021-00816-x  0.32
2021 McIntyre RS, Rosenblat JD, Nemeroff CB, Sanacora G, Murrough JW, Berk M, Brietzke E, Dodd S, Gorwood P, Ho R, Iosifescu DV, Lopez Jaramillo C, Kasper S, Kratiuk K, Lee JG, ... ... Zarate CA, et al. Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation. The American Journal of Psychiatry. appiajp202020081251. PMID 33726522 DOI: 10.1176/appi.ajp.2020.20081251  0.374
2021 Ballard ED, Gilbert JR, Wusinich C, Zarate CA. New Methods for Assessing Rapid Changes in Suicide Risk. Frontiers in Psychiatry. 12: 598434. PMID 33574775 DOI: 10.3389/fpsyt.2021.598434  0.598
2020 Kadriu B, Greenwald M, Henter ID, Gilbert JR, Kraus C, Park LT, Zarate CA. Ketamine and Serotonergic Psychedelics: Common Mechanisms Underlying the Effects of Rapid-Acting Antidepressants. The International Journal of Neuropsychopharmacology. PMID 33252694 DOI: 10.1093/ijnp/pyaa087  0.627
2020 Ballard ED, Gilbert JR, Fields JS, Nugent AC, Zarate CA. Network Changes in Insula and Amygdala Connectivity Accompany Implicit Suicidal Associations. Frontiers in Psychiatry. 11: 577628. PMID 33192714 DOI: 10.3389/fpsyt.2020.577628  0.598
2020 Lundin NB, Sepe-Forrest L, Gilbert JR, Carver FW, Furey ML, Zarate CA, Nugent AC. Ketamine Alters Electrophysiological Responses to Emotional Faces in Major Depressive Disorder. Journal of Affective Disorders. 279: 239-249. PMID 33074143 DOI: 10.1016/j.jad.2020.10.007  0.831
2020 Bahji A, Vazquez GH, Zarate CA. Comparative efficacy of racemic ketamine and esketamine for depression: A systematic review and meta-analysis. Journal of Affective Disorders. 278: 542-555. PMID 33022440 DOI: 10.1016/j.jad.2020.09.071  0.375
2020 Mkrtchian A, Evans JW, Kraus C, Yuan P, Kadriu B, Nugent AC, Roiser JP, Zarate CA. Ketamine modulates fronto-striatal circuitry in depressed and healthy individuals. Molecular Psychiatry. PMID 32929215 DOI: 10.1038/S41380-020-00878-1  0.813
2020 Acevedo-Diaz EE, Cavanaugh GW, Greenstein D, Kraus C, Kadriu B, Park L, Zarate CA. Can 'floating' predict treatment response to ketamine? Data from three randomized trials of individuals with treatment-resistant depression. Journal of Psychiatric Research. 130: 280-285. PMID 32861983 DOI: 10.1016/J.Jpsychires.2020.06.012  0.484
2020 Nugent AC, Ballard ED, Gilbert JR, Tewarie PK, Brookes MJ, Zarate CA. Multilayer MEG functional connectivity as a potential marker for suicidal thoughts in major depressive disorder. Neuroimage. Clinical. 28: 102378. PMID 32836087 DOI: 10.1016/J.Nicl.2020.102378  0.706
2020 Gilbert JR, Zarate CA. Biologically plausible models of neural dynamics for rapid-acting antidepressant interventions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32801348 DOI: 10.1038/S41386-020-00804-7  0.61
2020 Ching CRK, Hibar DP, Gurholt TP, Nunes A, Thomopoulos SI, Abé C, Agartz I, Brouwer RM, Cannon DM, de Zwarte SMC, Eyler LT, Favre P, Hajek T, Haukvik UK, Houenou J, ... ... Zarate CA, et al. What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group. Human Brain Mapping. PMID 32725849 DOI: 10.1002/Hbm.25098  0.346
2020 Park LT, Luckenbaugh DA, Pennybaker SJ, Hopkins MA, Henter ID, Lener MS, Kadriu B, Ballard ED, Zarate CA. The Effects of Ketamine on Typical and Atypical Depressive Symptoms. Acta Psychiatrica Scandinavica. PMID 32677051 DOI: 10.1111/acps.13216  0.328
2020 Nugent AC, Ballard ED, Gilbert JR, Tewarie PK, Brookes MJ, Zarate CA. The Effect of Ketamine on Electrophysiological Connectivity in Major Depressive Disorder. Frontiers in Psychiatry. 11: 519. PMID 32655423 DOI: 10.3389/Fpsyt.2020.00519  0.717
2020 Kadriu B, Ballard ED, Henter ID, Murata S, Gerlus N, Zarate CA. Neurobiological biomarkers of response to ketamine. Advances in Pharmacology (San Diego, Calif.). 89: 195-235. PMID 32616207 DOI: 10.1016/Bs.Apha.2020.05.003  0.409
2020 Schmaal L, Pozzi E, C Ho T, van Velzen LS, Veer IM, Opel N, Van Someren EJW, Han LKM, Aftanas L, Aleman A, Baune BT, Berger K, Blanken TF, Capitão L, Couvy-Duchesne B, ... ... Zarate C, et al. ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing. Translational Psychiatry. 10: 172. PMID 32472038 DOI: 10.1038/S41398-020-0842-6  0.341
2020 Kadriu B, Deng ZD, Kraus C, Henter ID, Lisanby SH, Zarate CA. Not So Fast: Recent Successes and Failures in Treating Depression. The Journal of Clinical Psychiatry. 81. PMID 32459405 DOI: 10.4088/Jcp.19Ac13138  0.425
2020 Farmer CA, Gilbert JR, Moaddel R, George J, Adeojo L, Lovett J, Nugent AC, Kadriu B, Yuan P, Gould TD, Park LT, Zarate CA. Correction: Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32376872 DOI: 10.1038/s41386-020-0699-7  0.649
2020 Farmer CA, Gilbert JR, Moaddel R, George J, Adeojo L, Lovett J, Nugent AC, Kadriu B, Yuan P, Gould TD, Park LT, Zarate CA. Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32252062 DOI: 10.1038/S41386-020-0663-6  0.65
2020 Park LT, Kadriu B, Gould TD, Zanos P, Greenstein D, Evans JW, Yuan P, Farmer CA, Oppenheimer M, George JM, Adeojo LW, Snodgrass HR, Smith MA, Henter ID, Machado-Vieira R, ... ... Zarate CA, et al. A Randomized Trial of the N-methyl-d-aspartate Receptor Glycine Site Antagonist Prodrug 4-chlorokynurenine in Treatment-Resistant Depression. The International Journal of Neuropsychopharmacology. PMID 32236521 DOI: 10.1093/Ijnp/Pyaa025  0.411
2020 Kraus C, Mkrtchian A, Kadriu B, Nugent AC, Zarate CA, Evans JW. Evaluating global brain connectivity as an imaging marker for depression: influence of preprocessing strategies and placebo-controlled ketamine treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31995812 DOI: 10.1038/S41386-020-0624-0  0.768
2020 Gilbert JR, Zarate CA. Electrophysiological biomarkers of antidepressant response to ketamine in treatment-resistant depression: Gamma power and long-term potentiation. Pharmacology, Biochemistry, and Behavior. 172856. PMID 31958471 DOI: 10.1016/J.Pbb.2020.172856  0.706
2020 Nugent AC, Ballard ED, Gilbert JR, Tewarie PK, Brookes MJ, Zarate CA. The Effect of Ketamine on Electrophysiological Connectivity in Major Depressive Disorder Frontiers in Psychiatry. 11. DOI: 10.3389/fpsyt.2020.00519  0.708
2020 Wusinich C, Gilbert JR, Mustafa NL, Zarate CA. Electrophysiological Correlates of the Monetary Incentive Delay Task in Mood Disorders Biological Psychiatry. 87: S282. DOI: 10.1016/J.Biopsych.2020.02.728  0.633
2020 Mustafa N, Wusinich C, Gilbert J, Luber B, Halberstadt A, Lisanby S, Zarate C, Deng Z. Using Mnemonic Similarity Task to Assess Medial Temporal Lobe Function: A Magnetoencephalography Study Biological Psychiatry. 87: S237-S238. DOI: 10.1016/J.Biopsych.2020.02.616  0.6
2020 Gilbert J, Ballard E, Fields J, Zarate C. Electrophysiological Correlates of the Suicide Implicit Association Task Biological Psychiatry. 87: S169. DOI: 10.1016/J.Biopsych.2020.02.447  0.622
2020 Ballard E, Gilbert J, Fields J, Farmer C, Zarate C. Mood Induction Paradigm in a Depressed Patient Sample Using Magnetoencephalography Biological Psychiatry. 87: S416. DOI: 10.1016/J.Biopsych.2020.02.1062  0.706
2019 Park LT, Falodun TB, Zarate CA. Ketamine for Treatment-Resistant Mood Disorders. Focus (American Psychiatric Publishing). 17: 8-12. PMID 31975953 DOI: 10.1176/appi.focus.20180030  0.354
2019 Gilbert JR, Ballard ED, Galiano CS, Nugent AC, Zarate CA. Magnetoencephalographic Correlates of Suicidal Ideation in Major Depression. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 31928949 DOI: 10.1016/J.Bpsc.2019.11.011  0.7
2019 Acevedo-Diaz EE, Cavanaugh GW, Greenstein D, Kraus C, Kadriu B, Zarate CA, Park LT. Comprehensive assessment of side effects associated with a single dose of ketamine in treatment-resistant depression. Journal of Affective Disorders. PMID 31791675 DOI: 10.1016/J.Jad.2019.11.028  0.419
2019 Ballard ED, Farmer CA, Shovestul B, VandeVoort J, Machado-Vieira R, Park L, Merikangas KR, Zarate CA. Symptom Trajectories in the Months Before and After a Suicide Attempt in Individuals with Bipolar Disorder:A STEP-BD Study. Bipolar Disorders. PMID 31737973 DOI: 10.1111/Bdi.12873  0.33
2019 Kadriu B, Farmer CA, Yuan P, Park LT, Deng ZD, Moaddel R, Henter ID, Shovestul B, Ballard ED, Kraus C, Gold PW, Machado-Vieira R, Zarate CA. The kynurenine pathway and bipolar disorder: intersection of the monoaminergic and glutamatergic systems and immune response. Molecular Psychiatry. PMID 31732715 DOI: 10.1038/S41380-019-0589-8  0.416
2019 Kraus C, Wasserman D, Henter ID, Acevedo-Diaz E, Kadriu B, Zarate CA. The influence of ketamine on drug discovery in depression. Drug Discovery Today. PMID 31382015 DOI: 10.1016/J.Drudis.2019.07.007  0.467
2019 Nugent AC, Farmer C, Evans JW, Snider SL, Banerjee D, Zarate CA. Multimodal imaging reveals a complex pattern of dysfunction in corticolimbic pathways in major depressive disorder. Human Brain Mapping. PMID 31179620 DOI: 10.1002/Hbm.24679  0.415
2019 Szczepanik JE, Reed JL, Nugent AC, Ballard ED, Evans JW, Lejuez CW, Zarate CA. Correction to: Mapping anticipatory anhedonia: an fMRI study. Brain Imaging and Behavior. PMID 31172359 DOI: 10.1007/S11682-019-00131-6  0.731
2019 Nolen WA, Licht RW, Young AH, Malhi GS, Tohen M, Vieta E, Kupka RW, Zarate C, Nielsen RE, Baldessarini R, Severus E. What is the optimal serum level for lithium in the maintenance treatment of bipolar disorder? A systematic review and recommendations from the ISBD/IGSLI Task Force on treatment with lithium. Bipolar Disorders. PMID 31112628 DOI: 10.1111/Bdi.12805  0.311
2019 Szczepanik JE, Reed JL, Nugent AC, Ballard ED, Evans JW, Lejuez CW, Zarate CA. Mapping anticipatory anhedonia: an fMRI study. Brain Imaging and Behavior. PMID 31030316 DOI: 10.1007/S11682-019-00084-W  0.79
2019 Zanos P, Highland JN, Stewart BW, Georgiou P, Jenne CE, Lovett J, Morris PJ, Thomas CJ, Moaddel R, Zarate CA, Gould TD. ()-hydroxynorketamine exerts mGlu receptor-dependent antidepressant actions. Proceedings of the National Academy of Sciences of the United States of America. PMID 30867285 DOI: 10.1073/Pnas.1819540116  0.375
2019 Reed JL, Nugent AC, Furey ML, Szczepanik JE, Evans JW, Zarate CA. Effects of Ketamine on Brain Activity During Emotional Processing: Differential Findings in Depressed Versus Healthy Control Participants. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 30826253 DOI: 10.1016/J.Bpsc.2019.01.005  0.806
2019 Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris PJ, Thomas CJ, Zarate CA, et al. Antidepressant-relevant concentrations of the ketamine metabolite (2,6)-hydroxynorketamine do not block NMDA receptor function. Proceedings of the National Academy of Sciences of the United States of America. PMID 30796190 DOI: 10.1073/Pnas.1816071116  0.303
2019 Ballard ED, Reed JL, Szczepanik J, Evans JW, Yarrington JS, Dickstein DP, Nock MK, Nugent AC, Zarate CA. Functional Imaging of the Implicit Association of the Self With Life and Death. Suicide & Life-Threatening Behavior. PMID 30761601 DOI: 10.1111/Sltb.12543  0.748
2019 Ballard ED, Vande Voort JL, Bernert RA, Luckenbaugh DA, Richards EM, Niciu MJ, Furey ML, Duncan WC, Zarate CA. Correction. Nocturnal Wakefulness Is Associated With Next-Day Suicidal Ideation in Major Depressive Disorder and Bipolar Disorder The Journal of Clinical Psychiatry. 77: e1655. PMID 28086017 DOI: 10.4088/JCP.16lcx11319  0.323
2019 Fields J, Gilbert J, Ballard E, Waldman L, Zarate C. F125. Magnetoencephalography of the Suicide Implicit Association Task Biological Psychiatry. 85: S261-S262. DOI: 10.1016/J.Biopsych.2019.03.662  0.62
2019 Reed J, Evans J, Nugent A, Szczepanik J, Zarate C. F123. Comparison of fMRI Emotional Processing Tasks Used for Detecting Effects of Ketamine and Predicting Response in Depression Biological Psychiatry. 85: S261. DOI: 10.1016/J.Biopsych.2019.03.660  0.792
2019 Gilbert J, Nugent A, Zarate C. F118. Ketamine and Attentional Bias to Threat: Dynamic Causal Modeling of AMPA and NMDA Connectivity Estimates From Magnetoencephalography Biological Psychiatry. 85: S259. DOI: 10.1016/J.Biopsych.2019.03.655  0.607
2019 Mkrtchian A, Evans J, Farmer C, Greenstein D, Nugent A, Zarate C. F108. The Relationship Between the Habenula, Motivational Symptoms, and Ketamine Treatment Biological Psychiatry. 85: S255. DOI: 10.1016/J.Biopsych.2019.03.645  0.714
2018 Park L, Furey M, Nugent A, Farmer C, Ellis J, Szczepanik J, Lener M, Zarate C. RETRACTED: F173. Negative Trial of Scopolamine in Major Depressive Disorder Does Not Demonstrate Neurophysiological Changes Seen With the Antidepressant Response of Ketamine. Biological Psychiatry. 83: S305-S306. PMID 32005321 DOI: 10.1016/J.Biopsych.2018.02.787  0.364
2018 Guo W, Machado-Vieira R, Mathew S, Murrough JW, Charney DS, Gruenbaum M, Oquendo MA, Kadriu B, Akula N, Henter I, Yuan P, Merikangas K, Drevets W, Furey M, Mann JJ, ... ... Zarate CA, et al. Exploratory genome-wide association analysis of response to ketamine and a polygenic analysis of response to scopolamine in depression. Translational Psychiatry. 8: 280. PMID 30552317 DOI: 10.1038/S41398-018-0311-7  0.484
2018 Nugent AC, Wills KE, Gilbert JR, Zarate CA. Synaptic potentiation and rapid antidepressant response to ketamine in treatment-resistant major depression: A replication study. Psychiatry Research. Neuroimaging. 283: 64-66. PMID 30551012 DOI: 10.1016/J.Pscychresns.2018.09.001  0.721
2018 Highland JN, Morris PJ, Zanos P, Lovett J, Ghosh S, Wang AQ, Zarate CA, Thomas CJ, Moaddel R, Gould TD. Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine. Journal of Psychopharmacology (Oxford, England). 269881118812095. PMID 30488740 DOI: 10.1177/0269881118812095  0.328
2018 Kadriu B, Musazzi L, Henter ID, Graves M, Popoli M, Zarate CA. Glutamatergic Neurotransmission: Pathway to Developing Novel Rapid-Acting Antidepressant Treatments. The International Journal of Neuropsychopharmacology. PMID 30445512 DOI: 10.1093/Ijnp/Pyy094  0.461
2018 Saligan LN, Farmer C, Ballard ED, Kadriu B, Zarate CA. Disentangling the association of depression on the anti-fatigue effects of ketamine. Journal of Affective Disorders. 244: 42-45. PMID 30312839 DOI: 10.1016/J.Jad.2018.10.089  0.453
2018 Gould TD, Zarate CA, Thompson SM. Molecular Pharmacology and Neurobiology of Rapid-Acting Antidepressants. Annual Review of Pharmacology and Toxicology. PMID 30296896 DOI: 10.1146/Annurev-Pharmtox-010617-052811  0.436
2018 Park L, Furey M, Nugent AC, Farmer C, Ellis J, Szczepanik J, Lener MS, Zarate CA. Neurophysiological Changes Associated with Antidepressant Response to Ketamine Not Observed in a Negative Trial of Scopolamine in Major Depressive Disorder. The International Journal of Neuropsychopharmacology. PMID 30184133 DOI: 10.1093/Ijnp/Pyy051  0.497
2018 Moaddel R, Shardell M, Khadeer M, Lovett J, Kadriu B, Ravichandran S, Morris PJ, Yuan P, Thomas CJ, Gould TD, Ferrucci L, Zarate CA. Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects. Psychopharmacology. PMID 30116859 DOI: 10.1007/S00213-018-4992-7  0.47
2018 Sinyor M, Williams M, Belo S, Orser B, Vincent M, Mah L, Zarate C, Castel S, Levitt AJ, Schaffer A. Ketamine augmentation for major depressive disorder and suicidal ideation: Preliminary experience in an inpatient psychiatry setting. Journal of Affective Disorders. 241: 103-109. PMID 30107350 DOI: 10.1016/J.Jad.2018.07.073  0.452
2018 Reed JL, Nugent AC, Furey ML, Szczepanik JE, Evans JW, Zarate CA. Ketamine normalizes brain activity during emotionally valenced attentional processing in depression. Neuroimage. Clinical. 20: 92-101. PMID 30094160 DOI: 10.1016/J.Nicl.2018.07.006  0.813
2018 Richards EM, Zanotti-Fregonara P, Fujita M, Newman L, Farmer C, Ballard ED, Machado-Vieira R, Yuan P, Niciu MJ, Lyoo CH, Henter ID, Salvadore G, Drevets WC, Kolb H, Innis RB, ... Zarate CA, et al. PET radioligand binding to translocator protein (TSPO) is increased in unmedicated depressed subjects. Ejnmmi Research. 8: 57. PMID 29971587 DOI: 10.1186/S13550-018-0401-9  0.437
2018 Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas CJ, Zarate CA, Gould TD. Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms. Pharmacological Reviews. 70: 621-660. PMID 29945898 DOI: 10.1124/Pr.117.015198  0.309
2018 Evans JW, Lally N, An L, Li N, Nugent AC, Banerjee D, Snider SL, Shen J, Roiser JP, Zarate CA. 7T H-MRS in major depressive disorder: a Ketamine Treatment Study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29748628 DOI: 10.1038/S41386-018-0057-1  0.777
2018 Gilbert JR, Yarrington JS, Wills KE, Nugent AC, Zarate CA. Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling. The International Journal of Neuropsychopharmacology. PMID 29668918 DOI: 10.1093/Ijnp/Pyy041  0.736
2018 Evans JW, Szczepanik J, Brutsché N, Park LT, Nugent AC, Zarate CA. Default Mode Connectivity in Major Depressive Disorder Measured Up to 10 Days After Ketamine Administration. Biological Psychiatry. PMID 29580569 DOI: 10.1016/J.Biopsych.2018.01.027  0.442
2018 Zanos P, Thompson SM, Duman RS, Zarate CA, Gould TD. Convergent Mechanisms Underlying Rapid Antidepressant Action. Cns Drugs. PMID 29516301 DOI: 10.1007/S40263-018-0492-X  0.421
2018 Niciu MJ, Shovestul BJ, Jaso BA, Farmer C, Luckenbaugh DA, Brutsche NE, Park LT, Ballard ED, Zarate CA. Features of dissociation differentially predict antidepressant response to ketamine in treatment-resistant depression. Journal of Affective Disorders. 232: 310-315. PMID 29501990 DOI: 10.1016/J.Jad.2018.02.049  0.443
2018 Nugent AC, Ballard ED, Gould TD, Park LT, Moaddel R, Brutsche NE, Zarate CA. Ketamine has distinct electrophysiological and behavioral effects in depressed and healthy subjects. Molecular Psychiatry. PMID 29487402 DOI: 10.1038/S41380-018-0028-2  0.426
2018 Henter ID, de Sousa RT, Zarate CA. Glutamatergic Modulators in Depression. Harvard Review of Psychiatry. PMID 29465478 DOI: 10.1097/Hrp.0000000000000183  0.493
2018 Ballard ED, Yarrington JS, Farmer CA, Lener MS, Kadriu B, Lally N, Williams D, Machado-Vieira R, Niciu MJ, Park L, Zarate CA. Parsing the heterogeneity of depression: An exploratory factor analysis across commonly used depression rating scales. Journal of Affective Disorders. 231: 51-57. PMID 29448238 DOI: 10.1016/J.Jad.2018.01.027  0.761
2018 Oppenheimer M, Falodun B, Hejazi N, Ballard E, Duncan WC, Zarate CA. S97. Insomnia is Associated With Response to Ketamine Administration in Patients With Major Depressive Disorder Biological Psychiatry. 83: S384-S385. DOI: 10.1016/J.Biopsych.2018.02.988  0.474
2018 Falodun T, Ballard E, Duncan WC, Hejazi N, Zarate C. S96. Wrist Actigraphy in Depressed Suicide Ideators and Non-Ideators Before and After Ketamine Biological Psychiatry. 83: S384. DOI: 10.1016/J.Biopsych.2018.02.987  0.446
2018 Galiano C, Nugent A, Gilbert J, Ballard E, Zarate C. F147. Resting State Oscillatory Power and Risk of Suicide in Depressed Patients Biological Psychiatry. 83: S295. DOI: 10.1016/J.Biopsych.2018.02.761  0.681
2018 Gerlus N, Ballard E, Reed J, Nugent A, Szczepanik J, Zarate C. F145. Differences in Emotional Attention Biases Between Suicide Attempters and Depressed Non-Attempters Biological Psychiatry. 83: S294. DOI: 10.1016/J.Biopsych.2018.02.759  0.794
2018 Reed J, Nugent A, Furey M, Szczepanik J, Evans J, Zarate C. F136. Antidepressant Effects of Ketamine Versus Placebo are Differentially Associated With Brain Activity During Emotional Processing Biological Psychiatry. 83: S290-S291. DOI: 10.1016/J.Biopsych.2018.02.749  0.759
2018 Gilbert J, Galiano C, Nugent A, Zarate C. T139. Ketamine and Attentional Bias to Threat: MEG Correlates of Stimulus-Evoked Gamma-Band Response Biological Psychiatry. 83: S182. DOI: 10.1016/J.Biopsych.2018.02.476  0.594
2018 Glaus J, Cui L, Zarate C, Merikangas K. T116. Atypical Depression and Sleep Patterns Using a Family Study Approach Biological Psychiatry. 83: S173. DOI: 10.1016/J.Biopsych.2018.02.452  0.331
2018 Szczepanik J, Reed J, Nugent A, Zarate C, Ballard E. T114. Depressed Patients With History of Suicide Attempts Differ From Non-Attempters in Processing of Emotional Faces Biological Psychiatry. 83: S172-S173. DOI: 10.1016/J.Biopsych.2018.02.450  0.791
2017 Niciu MJ, Iadarola ND, Banerjee D, Luckenbaugh DA, Park M, Lener M, Park L, Ionescu DF, Ballard ED, Brutsche NE, Akula N, McMahon FJ, Machado-Vieira R, Nugent AC, Zarate CA. The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder. Journal of Psychopharmacology (Oxford, England). 269881117732514. PMID 29039254 DOI: 10.1177/0269881117732514  0.349
2017 Duncan WC, Ballard ED, Zarate CA. Ketamine-Induced Glutamatergic Mechanisms of Sleep and Wakefulness: Insights for Developing Novel Treatments for Disturbed Sleep and Mood. Handbook of Experimental Pharmacology. PMID 28939975 DOI: 10.1007/164_2017_51  0.364
2017 Ballard ED, Snider SL, Nugent AC, Luckenbaugh DA, Park L, Zarate CA. Active suicidal ideation during clinical antidepressant trials. Psychiatry Research. 257: 303-308. PMID 28787656 DOI: 10.1016/J.Psychres.2017.07.065  0.39
2017 Kadriu B, Gold PW, Luckenbaugh DA, Lener MS, Ballard ED, Niciu MJ, Henter ID, Park LT, De Sousa RT, Yuan P, Machado-Vieira R, Zarate CA. Acute ketamine administration corrects abnormal inflammatory bone markers in major depressive disorder. Molecular Psychiatry. PMID 28555075 DOI: 10.1038/Mp.2017.109  0.315
2017 Ballard ED, Wills K, Lally N, Richards EM, Luckenbaugh DA, Walls T, Ameli R, Niciu MJ, Brutsche NE, Park L, Zarate CA. Anhedonia as a clinical correlate of suicidal thoughts in clinical ketamine trials. Journal of Affective Disorders. 218: 195-200. PMID 28477497 DOI: 10.1016/J.Jad.2017.04.057  0.733
2017 Hibar DP, Westlye LT, Doan NT, Jahanshad N, Cheung JW, Ching CRK, Versace A, Bilderbeck AC, Uhlmann A, Mwangi B, Krämer B, Overs B, Hartberg CB, Abé C, Dima D, ... ... Zarate CA, et al. Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. Molecular Psychiatry. PMID 28461699 DOI: 10.1038/Mp.2017.73  0.331
2017 Park LT, Lener MS, Hopkins M, Iadorola N, Machado-Vieira R, Ballard E, Nugent A, Zarate CA. A Double-Blind, Placebo-Controlled, Pilot Study of Riluzole Monotherapy for Acute Bipolar Depression. Journal of Clinical Psychopharmacology. PMID 28338546 DOI: 10.1097/Jcp.0000000000000693  0.506
2017 Lener MS, Kadriu B, Zarate CA. Ketamine and Beyond: Investigations into the Potential of Glutamatergic Agents to Treat Depression. Drugs. PMID 28194724 DOI: 10.1007/S40265-017-0702-8  0.513
2017 Zarate C, Nugent A, Machado-Vieira R, Evans J, Reed J, Park L. 416. The KET-MOA Study: New Findings into the Neurobiology of the Response/non-Response, and Relapse Processes Biological Psychiatry. 81: S170. DOI: 10.1016/J.Biopsych.2017.02.900  0.741
2017 Szczepanik J, Reed J, Nugent A, Ballard E, Zarate C. 825. Mapping Anticipatory Anhedonia: An fMRI Study Biological Psychiatry. 81: S335. DOI: 10.1016/J.Biopsych.2017.02.892  0.733
2017 Zanos P, Moaddel R, Morris P, Georgiou P, Fischell J, Elmer G, Alkondon M, Yuan P, Pribut H, Singh N, Dossou K, Fang Y, Huang X, Mayo C, Wainer I, ... ... Zarate C, et al. 790. Ketamine Exerts NMDAR Inhibition-Independent Antidepressant Actions via Its Hydroxynorketamine Metabolites Biological Psychiatry. 81: S321. DOI: 10.1016/J.Biopsych.2017.02.857  0.316
2017 Kadriu B, Gold P, Lener M, Ballard E, Niciu M, Yuan P, Luckenbaugh D, Machado-Vieira R, Zarate C. 1003. Acute Ketamine Administration Corrects Abnormal Inflammatory Bone Markers in Major Depression Biological Psychiatry. 81: S405-S406. DOI: 10.1016/J.Biopsych.2017.02.730  0.377
2017 Ballard E, Luckenbaugh D, Yarrington J, Lally N, Lener M, Machado-Vieira R, Kadriu B, Niciu M, Park L, Zarate C. 330. A Principal Components Analysis of Depression and Anhedonia Scales: Illustrating the Heterogeneity of Depression Biological Psychiatry. 81: S135. DOI: 10.1016/J.Biopsych.2017.02.345  0.753
2017 Airey M, Ballard E, Zarate C, Nugent A. 263. Beta Power in Magnetoencephalography as a Potential Neurobiological Marker for Risk of Suicide in Depressed Patients Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.277  0.385
2017 Reed J, Nugent A, Furey M, Szczepanik J, Evans J, Zarate C. 262. Ketamine’s Effects on Brain Function during Emotional Processing in Major Depressive Disorder Biological Psychiatry. 81: S108. DOI: 10.1016/J.Biopsych.2017.02.276  0.803
2017 Shovestul B, Jaso B, Luckenbaugh D, Park L, Niciu M, Zarate C. 199. Associations between Specific Dissociative Symptoms and Symptom Subsets and Anti-Depressant Response to Ketamine Biological Psychiatry. 81: S82-S83. DOI: 10.1016/J.Biopsych.2017.02.212  0.382
2016 Vande Voort JL, Ballard ED, Luckenbaugh DA, Bernert RA, Richards EM, Niciu MJ, Park LT, Machado-Vieira R, Duncan WC, Zarate CA. Antisuicidal Response Following Ketamine Infusion Is Associated With Decreased Nighttime Wakefulness in Major Depressive Disorder and Bipolar Disorder. The Journal of Clinical Psychiatry. PMID 27929610 DOI: 10.4088/Jcp.15M10440  0.457
2016 Pennybaker SJ, Niciu MJ, Luckenbaugh DA, Zarate CA. Symptomatology and predictors of antidepressant efficacy in extended responders to a single ketamine infusion. Journal of Affective Disorders. PMID 27839782 DOI: 10.1016/J.Jad.2016.10.026  0.485
2016 Zanos P, Moaddel R, Morris PJ, Wainer IW, Albuquerque EX, Thompson SM, Thomas CJ, Zarate CA, Gould TD. Reply to: Antidepressant Actions of Ketamine Versus Hydroxynorketamine. Biological Psychiatry. PMID 27817846 DOI: 10.1016/J.Biopsych.2016.08.039  0.354
2016 Tseng WL, Thomas LA, Harkins E, Stoddard J, Zarate CA, Pine DS, Leibenluft E, Brotman MA. Functional connectivity during masked and unmasked face emotion processing in bipolar disorder. Psychiatry Research. 258: 1-9. PMID 27814457 DOI: 10.1016/J.Pscychresns.2016.10.006  0.315
2016 Bernert RA, Luckenbaugh DA, Duncan WC, Iwata NG, Ballard ED, Zarate CA. Sleep architecture parameters as a putative biomarker of suicidal ideation in treatment-resistant depression. Journal of Affective Disorders. 208: 309-315. PMID 27810712 DOI: 10.1016/J.Jad.2016.08.050  0.351
2016 Henter ID, de Sousa RT, Gold PW, Brunoni AR, Zarate CA, Machado-Vieira R. Mood Therapeutics: Novel Pharmacological Approaches for Treating Depression. Expert Review of Clinical Pharmacology. PMID 27781556 DOI: 10.1080/17512433.2017.1253472  0.386
2016 Fujita M, Richards EM, Niciu MJ, Ionescu DF, Zoghbi SS, Hong J, Telu S, Hines CS, Pike VW, Zarate CA, Innis RB. cAMP signaling in brain is decreased in unmedicated depressed patients and increased by treatment with a selective serotonin reuptake inhibitor. Molecular Psychiatry. PMID 27725657 DOI: 10.1038/Mp.2016.171  0.437
2016 Park M, Newman LE, Gold PW, Luckenbaugh DA, Yuan P, Machado-Vieira R, Zarate CA. Change in cytokine levels is not associated with rapid antidepressant response to ketamine in treatment-resistant depression. Journal of Psychiatric Research. 84: 113-118. PMID 27718369 DOI: 10.1016/j.jpsychires.2016.09.025  0.318
2016 Berg HE, Ballard ED, Luckenbaugh DA, Nugent AC, Ionescu DF, Zarate CA. Recognition of emotional facial expressions in anxious and nonanxious depression. Comprehensive Psychiatry. 70: 1-8. PMID 27624417 DOI: 10.1016/J.Comppsych.2016.06.007  0.431
2016 Machado-Vieira R, Luckenbaugh DA, Ballard ED, Henter ID, Tohen M, Suppes T, Zarate CA. Increased Activity or Energy as a Primary Criterion for the Diagnosis of Bipolar Mania in DSM-5: Findings From the STEP-BD Study. The American Journal of Psychiatry. appiajp201615091132. PMID 27523498 DOI: 10.1176/Appi.Ajp.2016.15091132  0.327
2016 Lamers F, Cui L, Hickie IB, Roca C, Machado-Vieira R, Zarate CA, Merikangas KR. Familial aggregation and heritability of the melancholic and atypical subtypes of depression. Journal of Affective Disorders. 204: 241-246. PMID 27450632 DOI: 10.1016/J.Jad.2016.06.040  0.4
2016 Lener MS, Niciu MJ, Ballard ED, Park M, Park LT, Nugent AC, Zarate CA. Glutamate and Gamma-Aminobutyric Acid Systems in the Pathophysiology of Major Depression and Antidepressant Response to Ketamine. Biological Psychiatry. PMID 27449797 DOI: 10.1016/J.Biopsych.2016.05.005  0.379
2016 Szczepanik J, Nugent AC, Drevets WC, Khanna A, Zarate CA, Furey ML. Amygdala response to explicit sad face stimuli at baseline predicts antidepressant treatment response to scopolamine in major depressive disorder. Psychiatry Research. 254: 67-73. PMID 27366831 DOI: 10.1016/J.Pscychresns.2016.06.005  0.427
2016 Nugent AC, Robinson SE, Coppola R, Zarate CA. Preliminary differences in resting state MEG functional connectivity pre- and post-ketamine in major depressive disorder. Psychiatry Research. 254: 56-66. PMID 27362845 DOI: 10.1016/J.Pscychresns.2016.06.006  0.41
2016 Ballard ED, Vande Voort JL, Bernert RA, Luckenbaugh DA, Richards EM, Niciu MJ, Furey ML, Duncan WC, Zarate CA. Nocturnal Wakefulness Is Associated With Next-Day Suicidal Ideation in Major Depressive Disorder and Bipolar Disorder. The Journal of Clinical Psychiatry. 77: 825-831. PMID 27337418 DOI: 10.4088/Jcp.15M09943  0.343
2016 Ballard ED, Vande Voort JL, Luckenbaugh DA, Machado-Vieira R, Tohen M, Zarate CA. Acute risk factors for suicide attempts and death: prospective findings from the STEP-BD study. Bipolar Disorders. PMID 27233466 DOI: 10.1111/Bdi.12397  0.334
2016 Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, ... ... Zarate CA, et al. NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Nature. PMID 27144355 DOI: 10.1038/Nature17998  0.37
2016 Machado-Vieira R, Gold PW, Luckenbaugh DA, Ballard ED, Richards EM, Henter ID, De Sousa RT, Niciu MJ, Yuan P, Zarate CA. The role of adipokines in the rapid antidepressant effects of ketamine. Molecular Psychiatry. PMID 27046644 DOI: 10.1038/Mp.2016.36  0.342
2016 Jaso BA, Niciu MJ, Iadarola ND, Lally N, Richards EM, Park M, Ballard ED, Nugent AC, Machado-Vieira R, Zarate CA. THERAPEUTIC MODULATION OF GLUTAMATE RECEPTORS IN MAJOR DEPRESSIVE DISORDER. Current Neuropharmacology. PMID 26997505 DOI: 10.2174/1570159X14666160321123221  0.692
2016 Nugent AC, Iadarola ND, Miller FG, Luckenbaugh DA, Zarate CA. Safety of research into severe and treatment-resistant mood disorders: analysis of outcome data from 12 years of clinical trials at the US National Institute of Mental Health. The Lancet. Psychiatry. PMID 26971192 DOI: 10.1016/S2215-0366(16)00006-7  0.315
2016 Stoddard J, Gotts SJ, Brotman MA, Lever S, Hsu D, Zarate C, Ernst M, Pine DS, Leibenluft E. Aberrant intrinsic functional connectivity within and between corticostriatal and temporal-parietal networks in adults and youth with bipolar disorder. Psychological Medicine. 1-14. PMID 26924633 DOI: 10.1017/S0033291716000143  0.314
2016 Richards EM, Mathews DC, Luckenbaugh DA, Ionescu DF, Machado-Vieira R, Niciu MJ, Duncan WC, Nolan NM, Franco-Chaves JA, Hudzik T, Maciag C, Li S, Cross A, Smith MA, Zarate CA. A randomized, placebo-controlled pilot trial of the delta opioid receptor agonist AZD2327 in anxious depression. Psychopharmacology. PMID 26728893 DOI: 10.1007/S00213-015-4195-4  0.43
2016 Park M, Niciu MJ, Zarate CA. Erratum to: Novel Glutamatergic Treatments for Severe Mood Disorders Current Behavioral Neuroscience Reports. 3: 86-86. DOI: 10.1007/S40473-016-0069-2  0.335
2015 Park M, Niciu MJ, Zarate CA. Novel Glutamatergic Treatments for Severe Mood Disorders. Current Behavioral Neuroscience Reports. 2: 198-208. PMID 26824031 DOI: 10.1007/S40473-015-0050-5  0.384
2015 Zarate CA, Niciu MJ. Ketamine for depression: evidence, challenges and promise. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 14: 348-50. PMID 26407791 DOI: 10.1002/Wps.20269  0.506
2015 de Sousa RT, Streck EL, Forlenza OV, Brunoni AR, Zanetti MV, Ferreira GK, Diniz BS, Portela LV, Carvalho AF, Zarate CA, Gattaz WF, Machado-Vieira R. Regulation of leukocyte tricarboxylic acid cycle in drug-naïve Bipolar Disorder. Neuroscience Letters. 605: 65-8. PMID 26297865 DOI: 10.1016/J.Neulet.2015.08.022  0.377
2015 Zanos P, Piantadosi SC, Wu HQ, Pribut HJ, Dell MJ, Can A, Snodgrass HR, Zarate CA, Schwarcz R, Gould TD. The Prodrug 4-Chlorokynurenine Causes Ketamine-Like Antidepressant Effects, but Not Side Effects, by NMDA/GlycineB-Site Inhibition. The Journal of Pharmacology and Experimental Therapeutics. 355: 76-85. PMID 26265321 DOI: 10.1124/Jpet.115.225664  0.378
2015 Ballard ED, Luckenbaugh DA, Richards EM, Walls TL, Brutsché NE, Ameli R, Niciu MJ, Vande Voort JL, Zarate CA. Assessing measures of suicidal ideation in clinical trials with a rapid-acting antidepressant. Journal of Psychiatric Research. 68: 68-73. PMID 26228403 DOI: 10.1016/J.Jpsychires.2015.06.003  0.404
2015 Schaffer A, Isometsä ET, Tondo L, Moreno DH, Sinyor M, Kessing LV, Turecki G, Weizman A, Azorin JM, Ha K, Reis C, Cassidy F, Goldstein T, Rihmer Z, Beautrais A, ... ... Zarate CA, et al. Epidemiology, neurobiology and pharmacological interventions related to suicide deaths and suicide attempts in bipolar disorder: Part I of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder. The Australian and New Zealand Journal of Psychiatry. 49: 785-802. PMID 26185269 DOI: 10.1177/0004867415594427  0.341
2015 Schaffer A, Isometsä ET, Azorin JM, Cassidy F, Goldstein T, Rihmer Z, Sinyor M, Tondo L, Moreno DH, Turecki G, Reis C, Kessing LV, Ha K, Weizman A, Beautrais A, ... ... Zarate CA, et al. A review of factors associated with greater likelihood of suicide attempts and suicide deaths in bipolar disorder: Part II of a report of the International Society for Bipolar Disorders Task Force on Suicide in Bipolar Disorder. The Australian and New Zealand Journal of Psychiatry. PMID 26175498 DOI: 10.1177/0004867415594428  0.336
2015 Xu AJ, Niciu MJ, Lundin NB, Luckenbaugh DA, Ionescu DF, Richards EM, Vande Voort JL, Ballard ED, Brutsche NE, Machado-Vieira R, Zarate CA. Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression. Neural Plasticity. 2015: 858251. PMID 26137324 DOI: 10.1155/2015/858251  0.813
2015 Lally N, An L, Banerjee D, Niciu MJ, Luckenbaugh DA, Richards EM, Roiser JP, Shen J, Zarate CA, Nugent AC. Reliability of 7T (1) H-MRS measured human prefrontal cortex glutamate, glutamine, and glutathione signals using an adapted echo time optimized PRESS sequence: A between- and within-sessions investigation. Journal of Magnetic Resonance Imaging : Jmri. PMID 26059603 DOI: 10.1002/Jmri.24970  0.736
2015 Zarate CA, Machado-Vieira R. Potential Pathways Involved in the Rapid Antidepressant Effects of Nitrous Oxide. Biological Psychiatry. 78: 2-4. PMID 26051637 DOI: 10.1016/J.Biopsych.2015.04.007  0.395
2015 Nugent AC, Robinson SE, Coppola R, Furey ML, Zarate CA. Group differences in MEG-ICA derived resting state networks: Application to major depressive disorder. Neuroimage. 118: 1-12. PMID 26032890 DOI: 10.1016/J.Neuroimage.2015.05.051  0.366
2015 Iadarola ND, Niciu MJ, Richards EM, Vande Voort JL, Ballard ED, Lundin NB, Nugent AC, Machado-Vieira R, Zarate CA. Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review. Therapeutic Advances in Chronic Disease. 6: 97-114. PMID 25954495 DOI: 10.1177/2040622315579059  0.809
2015 Furey ML, Drevets WC, Szczepanik J, Khanna A, Nugent A, Zarate CA. Pretreatment Differences in BOLD Response to Emotional Faces Correlate with Antidepressant Response to Scopolamine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25820840 DOI: 10.1093/Ijnp/Pyv028  0.4
2015 Machado-Vieira R, Zanetti MV, Teixeira AL, Uno M, Valiengo LL, Soeiro-de-Souza MG, Oba-Shinjo SM, de Sousa RT, Zarate CA, Gattaz WF, Marie SK. Decreased AKT1/mTOR pathway mRNA expression in short-term bipolar disorder. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 25: 468-73. PMID 25726893 DOI: 10.1016/J.Euroneuro.2015.02.002  0.377
2015 Lally N, Nugent AC, Luckenbaugh DA, Niciu MJ, Roiser JP, Zarate CA. Neural correlates of change in major depressive disorder anhedonia following open-label ketamine. Journal of Psychopharmacology (Oxford, England). 29: 596-607. PMID 25691504 DOI: 10.1177/0269881114568041  0.812
2015 Ionescu DF, Nugent AC, Luckenbaugh DA, Niciu MJ, Richards EM, Zarate CA, Furey ML. Baseline working memory activation deficits in dimensional anxious depression as detected by magnetoencephalography. Acta Neuropsychiatrica. 27: 143-52. PMID 25600154 DOI: 10.1017/Neu.2014.46  0.484
2015 Teixeira AL, de Souza RT, Zanetti MV, Brunoni AR, Busatto GF, Zarate CA, Gattaz WF, Machado-Vieira R. Increased plasma levels of soluble TNF receptors 1 and 2 in bipolar depression and impact of lithium treatment. Human Psychopharmacology. 30: 52-6. PMID 25572309 DOI: 10.1002/Hup.2450  0.416
2015 Monteggia LM, Zarate C. Antidepressant actions of ketamine: from molecular mechanisms to clinical practice. Current Opinion in Neurobiology. 30: 139-43. PMID 25562451 DOI: 10.1016/J.Conb.2014.12.004  0.333
2015 Ballard ED, Lally N, Nugent AC, Furey ML, Luckenbaugh DA, Zarate CA. Neural correlates of suicidal ideation and its reduction in depression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25550331 DOI: 10.1093/Ijnp/Pyu069  0.728
2015 Ortiz R, Ulrich H, Zarate CA, Machado-Vieira R. Purinergic system dysfunction in mood disorders: a key target for developing improved therapeutics. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 57: 117-31. PMID 25445063 DOI: 10.1016/J.Pnpbp.2014.10.016  0.345
2015 Ionescu DF, Luckenbaugh DA, Niciu MJ, Richards EM, Zarate CA. A single infusion of ketamine improves depression scores in patients with anxious bipolar depression. Bipolar Disorders. 17: 438-43. PMID 25400146 DOI: 10.1111/Bdi.12277  0.502
2015 Schaffer A, Isometsä ET, Tondo L, H Moreno D, Turecki G, Reis C, Cassidy F, Sinyor M, Azorin JM, Kessing LV, Ha K, Goldstein T, Weizman A, Beautrais A, Chou YH, ... ... Zarate CA, et al. International Society for Bipolar Disorders Task Force on Suicide: meta-analyses and meta-regression of correlates of suicide attempts and suicide deaths in bipolar disorder. Bipolar Disorders. 17: 1-16. PMID 25329791 DOI: 10.1111/Bdi.12271  0.337
2015 Brunoni AR, Machado-Vieira R, Zarate CA, Vieira EL, Valiengo L, Benseñor IM, Lotufo PA, Gattaz WF, Teixeira AL. Assessment of non-BDNF neurotrophins and GDNF levels after depression treatment with sertraline and transcranial direct current stimulation in a factorial, randomized, sham-controlled trial (SELECT-TDCS): an exploratory analysis. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 56: 91-6. PMID 25172025 DOI: 10.1016/J.Pnpbp.2014.08.009  0.305
2015 Moaddel R, Luckenbaugh DA, Xie Y, Villaseñor A, Brutsche NE, Machado-Vieira R, Ramamoorthy A, Lorenzo MP, Garcia A, Bernier M, Torjman MC, Barbas C, Zarate CA, Wainer IW. D-serine plasma concentration is a potential biomarker of (R, S)-ketamine antidepressant response in subjects with treatment-resistant depression Psychopharmacology. 232: 399-409. PMID 25056852 DOI: 10.1007/S00213-014-3669-0  0.387
2015 Ballard ED, Lally N, Nugent AC, Furey ML, Luckenbaugh DA, Zarate CA. Neural correlates of suicidal ideation and its reduction in depression International Journal of Neuropsychopharmacology. 18. DOI: 10.1093/ijnp/pyu069  0.736
2014 Niciu MJ, Luckenbaugh DA, Ionescu DF, Richards EM, Vande Voort JL, Ballard ED, Brutsche NE, Furey ML, Zarate CA. Ketamine's antidepressant efficacy is extended for at least four weeks in subjects with a family history of an alcohol use disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25539512 DOI: 10.1093/Ijnp/Pyu039  0.41
2014 Ortiz R, Niciu MJ, Lukkahati N, Saligan LN, Nugent AC, Luckenbaugh DA, Machado-Vieira R, Zarate CA. Shank3 as a potential biomarker of antidepressant response to ketamine and its neural correlates in bipolar depression. Journal of Affective Disorders. 172: 307-311. PMID 25451430 DOI: 10.1016/J.Jad.2014.09.015  0.396
2014 Singh NS, Zarate CA, Moaddel R, Bernier M, Wainer IW. What is hydroxynorketamine and what can it bring to neurotherapeutics? Expert Review of Neurotherapeutics. 14: 1239-42. PMID 25331415 DOI: 10.1586/14737175.2014.971760  0.314
2014 Ionescu DF, Niciu MJ, Richards EM, Zarate CA. Pharmacologic treatment of dimensional anxious depression: a review. The Primary Care Companion For Cns Disorders. 16. PMID 25317369 DOI: 10.4088/Pcc.13R01621  0.443
2014 Lally N, Nugent AC, Luckenbaugh DA, Ameli R, Roiser JP, Zarate CA. Anti-anhedonic effect of ketamine and its neural correlates in treatment-resistant bipolar depression. Translational Psychiatry. 4: e469. PMID 25313512 DOI: 10.1038/Tp.2014.105  0.821
2014 Ionescu DF, Luckenbaugh DA, Niciu MJ, Richards EM, Slonena EE, Vande Voort JL, Brutsche NE, Zarate CA. Effect of baseline anxious depression on initial and sustained antidepressant response to ketamine. The Journal of Clinical Psychiatry. 75: e932-8. PMID 25295436 DOI: 10.4088/Jcp.14M09049  0.491
2014 Ballard ED, Ionescu DF, Vande Voort JL, Niciu MJ, Richards EM, Luckenbaugh DA, Brutsché NE, Ameli R, Furey ML, Zarate CA. Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety. Journal of Psychiatric Research. 58: 161-6. PMID 25169854 DOI: 10.1016/J.Jpsychires.2014.07.027  0.462
2014 Niciu MJ, Luckenbaugh DA, Ionescu DF, Richards EM, Vande Voort JL, Ballard ED, Brutsche NE, Furey ML, Zarate CA. Riluzole likely lacks antidepressant efficacy in ketamine non-responders. Journal of Psychiatric Research. 58: 197-9. PMID 25139008 DOI: 10.1016/J.Jpsychires.2014.07.022  0.39
2014 Ameli R, Luckenbaugh DA, Gould NF, Holmes MK, Lally N, Ballard ED, Zarate CA. SHAPS-C: the Snaith-Hamilton pleasure scale modified for clinician administration. Peerj. 2: e429. PMID 25024906 DOI: 10.7717/Peerj.429  0.731
2014 Lundin NB, Niciu MJ, Luckenbaugh DA, Ionescu DF, Richards EM, Vande Voort JL, Brutsche NE, Machado-Vieira R, Zarate CA. Baseline vitamin B12 and folate levels do not predict improvement in depression after a single infusion of ketamine. Pharmacopsychiatry. 47: 141-4. PMID 24955551 DOI: 10.1055/S-0034-1377042  0.806
2014 Niciu MJ, Luckenbaugh DA, Ionescu DF, Guevara S, Machado-Vieira R, Richards EM, Brutsche NE, Nolan NM, Zarate CA. Clinical predictors of ketamine response in treatment-resistant major depression. The Journal of Clinical Psychiatry. 75: e417-23. PMID 24922494 DOI: 10.4088/Jcp.13M08698  0.459
2014 Ballard ED, Ionescu DF, Vande Voort JL, Slonena EE, Franco-Chaves JA, Zarate CA, Grillon C. Increased fear-potentiated startle in major depressive disorder patients with lifetime history of suicide attempt. Journal of Affective Disorders. 162: 34-8. PMID 24767002 DOI: 10.1016/J.Jad.2014.03.027  0.395
2014 Brunoni AR, Machado-Vieira R, Zarate CA, Vieira EL, Vanderhasselt MA, Nitsche MA, Valiengo L, Benseñor IM, Lotufo PA, Gattaz WF, Teixeira AL. BDNF plasma levels after antidepressant treatment with sertraline and transcranial direct current stimulation: results from a factorial, randomized, sham-controlled trial. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 1144-51. PMID 24702987 DOI: 10.1016/J.Euroneuro.2014.03.006  0.433
2014 Villaseñor A, Ramamoorthy A, Silva Dos Santos M, Lorenzo MP, Laje G, Zarate C, Barbas C, Wainer IW. A pilot study of plasma metabolomic patterns from patients treated with ketamine for bipolar depression: Evidence for a response-related difference in mitochondrial networks British Journal of Pharmacology. 171: 2230-2242. PMID 24684390 DOI: 10.1111/Bph.12494  0.434
2014 Luckenbaugh DA, Niciu MJ, Ionescu DF, Nolan NM, Richards EM, Brutsche NE, Guevara S, Zarate CA. Do the dissociative side effects of ketamine mediate its antidepressant effects? Journal of Affective Disorders. 159: 56-61. PMID 24679390 DOI: 10.1016/J.Jad.2014.02.017  0.436
2014 Suppes T, Frank E, DePaulo JR, Davis L, Zarate CA, Angst J, Fawcett J. Letter to the editor in response to 2012 article by Frances and Jones. Bipolar Disorders. 16: 214-5. PMID 24597757 DOI: 10.1111/Bdi.12176  0.352
2014 Niciu MJ, Henter ID, Luckenbaugh DA, Zarate CA, Charney DS. Glutamate receptor antagonists as fast-acting therapeutic alternatives for the treatment of depression: ketamine and other compounds. Annual Review of Pharmacology and Toxicology. 54: 119-39. PMID 24392693 DOI: 10.1146/Annurev-Pharmtox-011613-135950  0.455
2014 de Sousa RT, Zarate CA, Zanetti MV, Costa AC, Talib LL, Gattaz WF, Machado-Vieira R. Oxidative stress in early stage Bipolar Disorder and the association with response to lithium. Journal of Psychiatric Research. 50: 36-41. PMID 24332923 DOI: 10.1016/J.Jpsychires.2013.11.011  0.405
2014 Niciu MJ, Ionescu DF, Richards EM, Zarate CA. Glutamate and its receptors in the pathophysiology and treatment of major depressive disorder. Journal of Neural Transmission (Vienna, Austria : 1996). 121: 907-24. PMID 24318540 DOI: 10.1007/S00702-013-1130-X  0.458
2014 Brunoni AR, Machado-Vieira R, Zarate CA, Valiengo L, Vieira EL, Benseñor IM, Lotufo PA, Gattaz WF, Teixeira AL. Cytokines plasma levels during antidepressant treatment with sertraline and transcranial direct current stimulation (tDCS): results from a factorial, randomized, controlled trial. Psychopharmacology. 231: 1315-23. PMID 24150249 DOI: 10.1007/S00213-013-3322-3  0.445
2014 Merikangas KR, Cui L, Heaton L, Nakamura E, Roca C, Ding J, Qin H, Guo W, Shugart YY, Yao-Shugart Y, Zarate C, Angst J. Independence of familial transmission of mania and depression: results of the NIMH family study of affective spectrum disorders. Molecular Psychiatry. 19: 214-9. PMID 24126930 DOI: 10.1038/Mp.2013.116  0.383
2014 Nugent AC, Diazgranados N, Carlson PJ, Ibrahim L, Luckenbaugh DA, Brutsche N, Herscovitch P, Drevets WC, Zarate CA. Neural correlates of rapid antidepressant response to ketamine in bipolar disorder Bipolar Disorders. 16: 119-128. PMID 24103187 DOI: 10.1111/Bdi.12118  0.42
2014 Niciu MJ, Henter ID, Sanacora G, Zarate CA. Glial abnormalities in substance use disorders and depression: does shared glutamatergic dysfunction contribute to comorbidity? The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 15: 2-16. PMID 24024876 DOI: 10.3109/15622975.2013.829585  0.408
2014 Machado-Vieira R, Soeiro-De-Souza MG, Richards EM, Teixeira AL, Zarate CA. Multiple levels of impaired neural plasticity and cellular resilience in bipolar disorder: developing treatments using an integrated translational approach. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 15: 84-95. PMID 23998912 DOI: 10.3109/15622975.2013.830775  0.322
2014 Brotman MA, Tseng WL, Olsavsky AK, Fromm SJ, Muhrer EJ, Rutenberg JG, Deveney CM, Adleman NE, Zarate CA, Pine DS, Leibenluft E. Fronto-limbic-striatal dysfunction in pediatric and adult patients with bipolar disorder: impact of face emotion and attentional demands. Psychological Medicine. 44: 1639-51. PMID 23930595 DOI: 10.1017/S003329171300202X  0.303
2014 Lally N, Nugent AC, Luckenbaugh DA, Zarate CA. Anti-anhedonic effect of ketamine and its neural correlates in major depressive disorder F1000research. 5. DOI: 10.7490/F1000Research.1095572.1  0.745
2014 Merikangas KR, Cui L, Heaton L, Nakamura E, Roca C, Ding J, Qin H, Guo W, Yao-Shugart Y, Zarate C, Angst J. Erratum: Independence of familial transmission of mania and depression: Results of the NIMH family study of affective spectrum disorders (Molecular Psychiatry (2014) 19:(272) doi:10.1038/mp.2013.116) Molecular Psychiatry. 19. DOI: 10.1038/Mp.2013.181  0.378
2014 Ballard ED, Voort JV, Luckenbaugh DA, Richards EM, Ionescu DF, Niciu MJ, Brutsche NE, Ameli R, Zarate CA. Suicidal ideation in the context of ketamine infusion: Relationship with depression and anxiety symptom clusters Comprehensive Psychiatry. 55: e45. DOI: 10.1016/J.Comppsych.2014.08.002  0.425
2013 Mathews DC, Richards EM, Niciu MJ, Ionescu DF, Rasimas JJ, Zarate CA. NEUROBIOLOGICAL ASPECTS OF SUICIDE AND SUICIDE ATTEMPTS IN BIPOLAR DISORDER. Translational Neuroscience. 4. PMID 24294519 DOI: 10.2478/S13380-013-0120-7  0.339
2013 Savitz J, Nugent AC, Bellgowan PS, Wright N, Tinsley R, Zarate CA, Herscovitch P, Drevets WC. Catecholamine depletion in first-degree relatives of individuals with mood disorders: An [(18)F]fluorodeoxyglucose positron emission tomography study. Neuroimage. Clinical. 2: 341-55. PMID 24179788 DOI: 10.1016/J.Nicl.2013.02.004  0.368
2013 Pacchiarotti I, Bond DJ, Baldessarini RJ, Nolen WA, Grunze H, Licht RW, Post RM, Berk M, Goodwin GM, Sachs GS, Tondo L, Findling RL, Youngstrom EA, Tohen M, Undurraga J, ... ... Zarate CA, et al. The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. The American Journal of Psychiatry. 170: 1249-62. PMID 24030475 DOI: 10.1176/Appi.Ajp.2013.13020185  0.381
2013 Furey ML, Zarate CA. Pulsed intravenous administration of scopolamine produces rapid antidepressant effects and modest side effects Journal of Clinical Psychiatry. 74: 850-851. PMID 24021505 DOI: 10.4088/Jcp.13Ac08584  0.444
2013 Nugent AC, Carlson PJ, Bain EE, Eckelman W, Herscovitch P, Manji H, Zarate CA, Drevets WC. Mood stabilizer treatment increases serotonin type 1A receptor binding in bipolar depression Journal of Psychopharmacology. 27: 894-902. PMID 23926239 DOI: 10.1177/0269881113499204  0.372
2013 Zarate C, Duman RS, Liu G, Sartori S, Quiroz J, Murck H. New paradigms for treatment-resistant depression. Annals of the New York Academy of Sciences. 1292: 21-31. PMID 23876043 DOI: 10.1111/Nyas.12223  0.5
2013 Nugent AC, Davis RM, Zarate CA, Drevets WC. Reduced thalamic volumes in major depressive disorder. Psychiatry Research. 213: 179-85. PMID 23850106 DOI: 10.1016/J.Pscychresns.2013.05.004  0.443
2013 Martinowich K, Jimenez DV, Zarate CA, Manji HK. Rapid antidepressant effects: moving right along. Molecular Psychiatry. 18: 856-63. PMID 23689537 DOI: 10.1038/Mp.2013.55  0.398
2013 Müller HK, Wegener G, Liebenberg N, Zarate CA, Popoli M, Elfving B. Ketamine regulates the presynaptic release machinery in the hippocampus Journal of Psychiatric Research. 47: 892-899. PMID 23548331 DOI: 10.1016/J.Jpsychires.2013.03.008  0.317
2013 Carlson PJ, Diazgranados N, Nugent AC, Ibrahim L, Luckenbaugh DA, Brutsche N, Herscovitch P, Manji HK, Zarate CA, Drevets WC. Neural correlates of rapid antidepressant response to ketamine in treatment-resistant unipolar depression: A preliminary positron emission tomography study Biological Psychiatry. 73: 1213-1221. PMID 23540908 DOI: 10.1016/J.Biopsych.2013.02.008  0.432
2013 Franco-Chaves JA, Mateus CF, Luckenbaugh DA, Martinez PE, Mallinger AG, Zarate CA. Combining a dopamine agonist and selective serotonin reuptake inhibitor for the treatment of depression: a double-blind, randomized pilot study. Journal of Affective Disorders. 149: 319-25. PMID 23517885 DOI: 10.1016/J.Jad.2013.02.003  0.425
2013 Ionescu DF, Niciu MJ, Henter ID, Zarate CA. Defining anxious depression: a review of the literature. Cns Spectrums. 18: 252-60. PMID 23507190 DOI: 10.1017/S1092852913000114  0.478
2013 Ionescu DF, Niciu MJ, Mathews DC, Richards EM, Zarate CA. Neurobiology of anxious depression: a review. Depression and Anxiety. 30: 374-85. PMID 23495126 DOI: 10.1002/Da.22095  0.491
2013 Niciu MJ, Ionescu DF, Mathews DC, Richards EM, Zarate CA. Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part II: bipolar disorder. Cns Spectrums. 18: 242-51. PMID 23472710 DOI: 10.1017/S1092852913000138  0.372
2013 Niciu MJ, Ionescu DF, Mathews DC, Richards EM, Zarate CA. Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part I: major depressive disorder. Cns Spectrums. 18: 231-41. PMID 23462230 DOI: 10.1017/S1092852913000059  0.406
2013 Zarate CA, Mathews DC, Furey ML. Human biomarkers of rapid antidepressant effects Biological Psychiatry. 73: 1142-1155. PMID 23374639 DOI: 10.1016/J.Biopsych.2012.11.031  0.457
2013 Furey ML, Drevets WC, Hoffman EM, Frankel E, Speer AM, Zarate CA. Potential of pretreatment neural activity in the visual cortex during emotional processing to predict treatment response to scopolamine in major depressive disorder. Jama Psychiatry. 70: 280-90. PMID 23364679 DOI: 10.1001/2013.Jamapsychiatry.60  0.47
2013 Zarate CA, Mathews D, Ibrahim L, Chaves JF, Marquardt C, Ukoh I, Jolkovsky L, Brutsche NE, Smith MA, Luckenbaugh DA. A randomized trial of a low-trapping nonselective N-methyl-D-aspartate channel blocker in major depression. Biological Psychiatry. 74: 257-64. PMID 23206319 DOI: 10.1016/J.Biopsych.2012.10.019  0.458
2013 Drevets WC, Zarate CA, Furey ML. Antidepressant effects of the muscarinic cholinergic receptor antagonist scopolamine: A review Biological Psychiatry. 73: 1156-1163. PMID 23200525 DOI: 10.1016/J.Biopsych.2012.09.031  0.481
2013 Soeiro-de-Souza MG, Salvadore G, Moreno RA, Otaduy MC, Chaim KT, Gattaz WF, Zarate CA, Machado-Vieira R. Bcl-2 rs956572 polymorphism is associated with increased anterior cingulate cortical glutamate in euthymic bipolar I disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 468-75. PMID 23072837 DOI: 10.1038/Npp.2012.203  0.324
2013 Duncan WC, Selter J, Brutsche N, Sarasso S, Zarate CA. Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder. Journal of Affective Disorders. 145: 115-9. PMID 22871531 DOI: 10.1016/J.Jad.2012.05.042  0.402
2013 Duncan WC, Sarasso S, Ferrarelli F, Selter J, Riedner BA, Hejazi NS, Yuan P, Brutsche N, Manji HK, Tononi G, Zarate CA. Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 301-11. PMID 22676966 DOI: 10.1017/S1461145712000545  0.389
2013 Nugent AC, Davis RM, Zarate CA, Drevets WC. Reduced thalamic volumes in major depressive disorder Psychiatry Research - Neuroimaging. 213: 179-185. DOI: 10.1016/j.pscychresns.2013.05.004  0.367
2012 de Sousa RT, Busnello JV, Forlenza OV, Zanetti MV, Soeiro-de-Souza MG, van de Bilt MT, Moreno RA, Zarate CA, Gattaz WF, Machado-Vieira R. Early improvement of psychotic symptoms with lithium monotherapy as a predictor of later response in mania. Journal of Psychiatric Research. 46: 1564-8. PMID 23000368 DOI: 10.1016/J.Jpsychires.2012.08.011  0.337
2012 Kaddurah-Daouk R, Yuan P, Boyle SH, Matson W, Wang Z, Zeng ZB, Zhu H, Dougherty GG, Yao JK, Chen G, Guitart X, Carlson PJ, Neumeister A, Zarate C, Krishnan RR, et al. Cerebrospinal fluid metabolome in mood disorders-remission state has a unique metabolic profile. Scientific Reports. 2: 667. PMID 22993692 DOI: 10.1038/Srep00667  0.428
2012 Luckenbaugh DA, Ibrahim L, Brutsche N, Franco-Chaves J, Mathews D, Marquardt CA, Cassarly C, Zarate CA. Family history of alcohol dependence and antidepressant response to an N-methyl-D-aspartate antagonist in bipolar depression. Bipolar Disorders. 14: 880-7. PMID 22978511 DOI: 10.1111/Bdi.12003  0.456
2012 Zanotti-Fregonara P, Hines CS, Zoghbi SS, Liow JS, Zhang Y, Pike VW, Drevets WC, Mallinger AG, Zarate CA, Fujita M, Innis RB. Population-based input function and image-derived input function for [¹¹C](R)-rolipram PET imaging: methodology, validation and application to the study of major depressive disorder. Neuroimage. 63: 1532-41. PMID 22906792 DOI: 10.1016/J.Neuroimage.2012.08.007  0.309
2012 Laje G, Lally N, Mathews D, Brutsche N, Chemerinski A, Akula N, Kelmendi B, Simen A, McMahon FJ, Sanacora G, Zarate C. Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients. Biological Psychiatry. 72: e27-8. PMID 22771240 DOI: 10.1016/J.Biopsych.2012.05.031  0.74
2012 Mathews DC, Henter ID, Zarate CA. Targeting the glutamatergic system to treat major depressive disorder: rationale and progress to date. Drugs. 72: 1313-33. PMID 22731961 DOI: 10.2165/11633130-000000000-00000  0.345
2012 Ibrahim L, Diaz Granados N, Jolkovsky L, Brutsche N, Luckenbaugh DA, Herring WJ, Potter WZ, Zarate CA. A Randomized, placebo-controlled, crossover pilot trial of the oral selective NR2B antagonist MK-0657 in patients with treatment-resistant major depressive disorder. Journal of Clinical Psychopharmacology. 32: 551-7. PMID 22722512 DOI: 10.1097/Jcp.0B013E31825D70D6  0.465
2012 Turner AD, Furey ML, Drevets WC, Zarate C, Nugent AC. Association between subcortical volumes and verbal memory in unmedicated depressed patients and healthy controls. Neuropsychologia. 50: 2348-55. PMID 22714007 DOI: 10.1016/J.Neuropsychologia.2012.06.003  0.425
2012 Aan Het Rot M, Zarate CA, Charney DS, Mathew SJ. Ketamine for depression: where do we go from here? Biological Psychiatry. 72: 537-47. PMID 22705040 DOI: 10.1016/J.Biopsych.2012.05.003  0.422
2012 Fujita M, Hines CS, Zoghbi SS, Mallinger AG, Dickstein LP, Liow JS, Zhang Y, Pike VW, Drevets WC, Innis RB, Zarate CA. Downregulation of brain phosphodiesterase type IV measured with 11C-(R)-rolipram positron emission tomography in major depressive disorder. Biological Psychiatry. 72: 548-54. PMID 22677471 DOI: 10.1016/J.Biopsych.2012.04.030  0.409
2012 Weathers JD, Stringaris A, Deveney CM, Brotman MA, Zarate CA, Connolly ME, Fromm SJ, LeBourdais SB, Pine DS, Leibenluft E. A developmental study of the neural circuitry mediating motor inhibition in bipolar disorder. The American Journal of Psychiatry. 169: 633-41. PMID 22581312 DOI: 10.1176/Appi.Ajp.2012.11081244  0.32
2012 Kim P, Thomas LA, Rosen BH, Moscicki AM, Brotman MA, Zarate CA, Blair RJ, Pine DS, Leibenluft E. Differing amygdala responses to facial expressions in children and adults with bipolar disorder. The American Journal of Psychiatry. 169: 642-9. PMID 22535257 DOI: 10.1176/Appi.Ajp.2012.11081245  0.303
2012 Cornwell BR, Salvadore G, Furey M, Marquardt CA, Brutsche NE, Grillon C, Zarate CA. Synaptic potentiation is critical for rapid antidepressant response to ketamine in treatment-resistant major depression. Biological Psychiatry. 72: 555-61. PMID 22521148 DOI: 10.1016/J.Biopsych.2012.03.029  0.475
2012 Zarate CA, Brutsche N, Laje G, Luckenbaugh DA, Venkata SL, Ramamoorthy A, Moaddel R, Wainer IW. Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression. Biological Psychiatry. 72: 331-8. PMID 22516044 DOI: 10.1016/J.Biopsych.2012.03.004  0.493
2012 Furey ML, Nugent AC, Speer AM, Luckenbaugh DA, Hoffman EM, Frankel E, Drevets WC, Zarate CA. Baseline mood-state measures as predictors of antidepressant response to scopolamine. Psychiatry Research. 196: 62-7. PMID 22349648 DOI: 10.1016/J.Psychres.2012.01.003  0.449
2012 Ibrahim L, Diazgranados N, Franco-Chaves J, Brutsche N, Henter ID, Kronstein P, Moaddel R, Wainer I, Luckenbaugh DA, Manji HK, Zarate CA. Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on riluzole: results from a 4-week, double-blind, placebo-controlled study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1526-33. PMID 22298121 DOI: 10.1038/Npp.2011.338  0.445
2012 Zarate CA, Brutsche NE, Ibrahim L, Franco-Chaves J, Diazgranados N, Cravchik A, Selter J, Marquardt CA, Liberty V, Luckenbaugh DA. Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial. Biological Psychiatry. 71: 939-46. PMID 22297150 DOI: 10.1016/J.Biopsych.2011.12.010  0.5
2012 Zhao X, Venkata SL, Moaddel R, Luckenbaugh DA, Brutsche NE, Ibrahim L, Zarate CA, Mager DE, Wainer IW. Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression. British Journal of Clinical Pharmacology. 74: 304-14. PMID 22295895 DOI: 10.1111/J.1365-2125.2012.04198.X  0.409
2012 Salvadore G, van der Veen JW, Zhang Y, Marenco S, Machado-Vieira R, Baumann J, Ibrahim LA, Luckenbaugh DA, Shen J, Drevets WC, Zarate CA. An investigation of amino-acid neurotransmitters as potential predictors of clinical improvement to ketamine in depression. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1063-72. PMID 22040773 DOI: 10.1017/S1461145711001593  0.427
2012 Machado-Vieira R, Ibrahim L, Henter ID, Zarate CA. Novel glutamatergic agents for major depressive disorder and bipolar disorder. Pharmacology, Biochemistry, and Behavior. 100: 678-87. PMID 21971560 DOI: 10.1016/J.Pbb.2011.09.010  0.412
2012 Malkesman O, Austin DR, Tragon T, Wang G, Rompala G, Hamidi AB, Cui Z, Young WS, Nakazawa K, Zarate CA, Manji HK, Chen G. Acute D-serine treatment produces antidepressant-like effects in rodents. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 15: 1135-48. PMID 21906419 DOI: 10.1017/S1461145711001386  0.4
2012 Zarate C, Furey M, Duncan W, Cornwell B, Sarasso S, Tononi G. S.04.01 Plasticity based therapeutics for the treatment of mood disorders European Neuropsychopharmacology. 22: S81-S82. DOI: 10.1016/S0924-977X(12)70086-X  0.33
2011 Manji HK, Henter ID, Zarate CA. Bipolar disorder: a neurobiological synthesis. Current Topics in Behavioral Neurosciences. 5: 331-40. PMID 25236563 DOI: 10.1007/7854_2010_98  0.329
2011 Machado-Vieira R, Manji HK, Zarate CA. Potential novel therapeutics for bipolar disorders. Current Topics in Behavioral Neurosciences. 5: 303-29. PMID 25236562 DOI: 10.1007/7854_2010_51  0.34
2011 Kupfer DJ, Angst J, Berk M, Dickerson F, Frangou S, Frank E, Goldstein BI, Harvey A, Laghrissi-Thode F, Leboyer M, Ostacher MJ, Sibille E, Strakowski SM, Suppes T, Tohen M, ... ... Zarate CA, et al. Advances in bipolar disorder: selected sessions from the 2011 International Conference on Bipolar Disorder. Annals of the New York Academy of Sciences. 1242: 1-25. PMID 22191553 DOI: 10.1111/J.1749-6632.2011.06336.X  0.324
2011 Javitt DC, Schoepp D, Kalivas PW, Volkow ND, Zarate C, Merchant K, Bear MF, Umbricht D, Hajos M, Potter WZ, Lee CM. Translating glutamate: from pathophysiology to treatment. Science Translational Medicine. 3: 102mr2. PMID 21957170 DOI: 10.1126/Scitranslmed.3002804  0.364
2011 Ibrahim L, Diazgranados N, Luckenbaugh DA, Machado-Vieira R, Baumann J, Mallinger AG, Zarate CA. Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 1155-9. PMID 21466832 DOI: 10.1016/J.Pnpbp.2011.03.019  0.492
2011 Savitz JB, Nugent AC, Bogers W, Roiser JP, Bain EE, Neumeister A, Zarate CA, Manji HK, Cannon DM, Marrett S, Henn F, Charney DS, Drevets WC. Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging study. Biological Psychiatry. 69: 336-43. PMID 21094939 DOI: 10.1016/J.Biopsych.2010.09.027  0.672
2011 Salvadore G, Nugent AC, Lemaitre H, Luckenbaugh DA, Tinsley R, Cannon DM, Neumeister A, Zarate CA, Drevets WC. Prefrontal cortical abnormalities in currently depressed versus currently remitted patients with major depressive disorder. Neuroimage. 54: 2643-51. PMID 21073959 DOI: 10.1016/J.Neuroimage.2010.11.011  0.45
2011 Mah L, Zarate CA, Nugent AC, Singh JB, Manji HK, Drevets WC. Neural mechanisms of antidepressant efficacy of the dopamine receptor agonist pramipexole in treatment of bipolar depression International Journal of Neuropsychopharmacology. 14: 545-551. PMID 21029512 DOI: 10.1017/S1461145710001203  0.461
2010 Machado-Vieira R, Baumann J, Wheeler-Castillo C, Latov D, Henter ID, Salvadore G, Zarate CA. The Timing of Antidepressant Effects: A Comparison of Diverse Pharmacological and Somatic Treatments. Pharmaceuticals (Basel, Switzerland). 3: 19-41. PMID 27713241 DOI: 10.3390/Ph3010019  0.457
2010 Fitzgerald PJ, Barkus C, Feyder M, Wiedholz LM, Chen YC, Karlsson RM, Machado-Vieira R, Graybeal C, Sharp T, Zarate C, Harvey-White J, Du J, Sprengel R, Gass P, Bannerman D, et al. Does gene deletion of AMPA GluA1 phenocopy features of schizoaffective disorder? Neurobiology of Disease. 40: 608-21. PMID 20699120 DOI: 10.1016/J.Nbd.2010.08.005  0.341
2010 Diazgranados N, Ibrahim L, Brutsche NE, Newberg A, Kronstein P, Khalife S, Kammerer WA, Quezado Z, Luckenbaugh DA, Salvadore G, Machado-Vieira R, Manji HK, Zarate CA. A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression Archives of General Psychiatry. 67: 793-802. PMID 20679587 DOI: 10.1001/Archgenpsychiatry.2010.90  0.456
2010 DiazGranados N, Ibrahim LA, Brutsche NE, Ameli R, Henter ID, Luckenbaugh DA, Machado-Vieira R, Zarate CA. Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder Journal of Clinical Psychiatry. 71: 1605-1611. PMID 20673547 DOI: 10.4088/Jcp.09M05327Blu  0.452
2010 Schaefer KL, Baumann J, Rich BA, Luckenbaugh DA, Zarate CA. Perception of facial emotion in adults with bipolar or unipolar depression and controls. Journal of Psychiatric Research. 44: 1229-35. PMID 20510425 DOI: 10.1016/J.Jpsychires.2010.04.024  0.453
2010 Salvadore G, Quiroz JA, Machado-Vieira R, Henter ID, Manji HK, Zarate CA. The neurobiology of the switch process in bipolar disorder: A review Journal of Clinical Psychiatry. 71: 1488-1501. PMID 20492846 DOI: 10.4088/Jcp.09R05259Gre  0.365
2010 Cornwell BR, Salvadore G, Colon-Rosario V, Latov DR, Holroyd T, Carver FW, Coppola R, Manji HK, Zarate CA, Grillon C. Abnormal hippocampal functioning and impaired spatial navigation in depressed individuals: evidence from whole-head magnetoencephalography. The American Journal of Psychiatry. 167: 836-44. PMID 20439387 DOI: 10.1176/Appi.Ajp.2009.09050614  0.457
2010 Machado-Vieira R, Salvadore G, DiazGranados N, Ibrahim L, Latov D, Wheeler-Castillo C, Baumann J, Henter ID, Zarate CA. New therapeutic targets for mood disorders. Thescientificworldjournal. 10: 713-26. PMID 20419280 DOI: 10.1100/Tsw.2010.65  0.381
2010 Salvadore G, Cornwell BR, Sambataro F, Latov D, Colon-Rosario V, Carver F, Holroyd T, DiazGranados N, Machado-Vieira R, Grillon C, Drevets WC, Zarate CA. Anterior cingulate desynchronization and functional connectivity with the amygdala during a working memory task predict rapid antidepressant response to ketamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1415-22. PMID 20393460 DOI: 10.1038/Npp.2010.24  0.35
2010 Tamayo JM, Zarate CA, Vieta E, Vazquez G, Tohen M. Level of response and safety of pharmacological monotherapy in the treatment of acute bipolar i disorder phases: A systematic review and meta-analysis International Journal of Neuropsychopharmacology. 13: 813-832. PMID 20128953 DOI: 10.1017/S1461145709991246  0.423
2010 Savitz J, Nugent AC, Bogers W, Liu A, Sills R, Luckenbaugh DA, Bain EE, Price JL, Zarate C, Manji HK, Cannon DM, Marrett S, Charney DS, Drevets WC. Amygdala volume in depressed patients with bipolar disorder assessed using high resolution 3T MRI: the impact of medication. Neuroimage. 49: 2966-76. PMID 19931399 DOI: 10.1016/J.Neuroimage.2009.11.025  0.321
2010 Fujita M, Mallinger AG, Zarate CA, Dickstein LP, Zoghbi SS, Pike VW, Zhang Y, Innis RB, Drevets WC. Changes of brain phosphodiesterase 4 in major depression Neuroimage. 52: S51. DOI: 10.1016/J.Neuroimage.2010.04.232  0.427
2009 Machado-Vieira R, Yuan P, Brutsche N, DiazGranados N, Luckenbaugh D, Manji HK, Zarate CA. Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist Journal of Clinical Psychiatry. 70: 1662-1666. PMID 19744406 DOI: 10.4088/Jcp.08M04659  0.355
2009 Tamayo JM, Sutton VK, Mattei MA, Diaz B, Jamal HH, Vieta E, Zarate CA, Fumero I, Tohen M. Effectiveness and safety of the combination of fluoxetine and olanzapine in outpatients with bipolar depression: an open-label, randomized, flexible-dose study in Puerto Rico. Journal of Clinical Psychopharmacology. 29: 358-61. PMID 19593175 DOI: 10.1097/Jcp.0B013E3181Ad223F  0.392
2009 Zarate CA, Manji HK. Protein kinase C inhibitors: Rationale for use and potential in the treatment of bipolar disorder Cns Drugs. 23: 569-582. PMID 19552485 DOI: 10.2165/00023210-200923070-00003  0.336
2009 Machado-Vieira R, Manji HK, Zarate CA. The role of lithium in the treatment of bipolar disorder: Convergent evidence for neurotrophic effects as a unifying hypothesis Bipolar Disorders. 11: 92-109. PMID 19538689 DOI: 10.1111/J.1399-5618.2009.00714.X  0.355
2009 MacHado-Vieira R, Manji HK, Zarate CA. The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders Neuroscientist. 15: 525-539. PMID 19471044 DOI: 10.1177/1073858409336093  0.36
2009 Machado-Vieira R, Salvadore G, Ibrahim LA, Diaz-Granados N, Zarate CA. Targeting glutamatergic signaling for the development of novel therapeutics for mood disorders Current Pharmaceutical Design. 15: 1595-1611. PMID 19442176 DOI: 10.2174/138161209788168010  0.397
2009 Machado-Vieira R, Salvadore G, DiazGranados N, Zarate CA. Ketamine and the next generation of antidepressants with a rapid onset of action Pharmacology and Therapeutics. 123: 143-150. PMID 19397926 DOI: 10.1016/J.Pharmthera.2009.02.010  0.453
2009 Roiser JP, Cannon DM, Gandhi SK, Taylor Tavares J, Erickson K, Wood S, Klaver JM, Clark L, Zarate CA, Sahakian BJ, Drevets WC. Hot and cold cognition in unmedicated depressed subjects with bipolar disorder. Bipolar Disorders. 11: 178-89. PMID 19267700 DOI: 10.1111/J.1399-5618.2009.00669.X  0.634
2009 Salvadore G, Cornwell BR, Colon-Rosario V, Coppola R, Grillon C, Zarate CA, Manji HK. Increased anterior cingulate cortical activity in response to fearful faces: a neurophysiological biomarker that predicts rapid antidepressant response to ketamine. Biological Psychiatry. 65: 289-95. PMID 18822408 DOI: 10.1016/J.Biopsych.2008.08.014  0.441
2008 Salvadore G, Drevets WC, Henter ID, Zarate CA, Manji HK. Early intervention in bipolar disorder, part II: therapeutics. Early Intervention in Psychiatry. 2: 136-46. PMID 19649153 DOI: 10.1111/J.1751-7893.2008.00072.X  0.338
2008 Salvadore G, Drevets WC, Henter ID, Zarate CA, Manji HK. Early intervention in bipolar disorder, part I: clinical and imaging findings. Early Intervention in Psychiatry. 2: 122-35. PMID 19649152 DOI: 10.1111/J.1751-7893.2008.00071.X  0.33
2008 Holmes MK, Erickson K, Luckenbaugh DA, Drevets WC, Bain EE, Cannon DM, Snow J, Sahakian BJ, Manji HK, Zarate CA. A comparison of cognitive functioning in medicated and unmedicated subjects with bipolar depression. Bipolar Disorders. 10: 806-15. PMID 19032712 DOI: 10.1111/J.1399-5618.2008.00628.X  0.391
2008 Zarate CA, Manji HK. Riluzole in psychiatry: a systematic review of the literature. Expert Opinion On Drug Metabolism & Toxicology. 4: 1223-34. PMID 18721116 DOI: 10.1517/17425255.4.9.1223  0.347
2008 Zarate CA, Manji HK. Bipolar disorder: candidate drug targets. The Mount Sinai Journal of Medicine, New York. 75: 226-47. PMID 18704977 DOI: 10.1002/Msj.20042  0.328
2008 Nowakowska C, Sachs GS, Zarate CA, Marangell LB, Calabrese JR, Goldberg JF, Ketter TA. Increased rate of non-right-handedness in patients with bipolar disorder. The Journal of Clinical Psychiatry. 69: 866-7. PMID 18681768 DOI: 10.4088/Jcp.V69N0522G  0.325
2008 Machado-Vieira R, Soares JC, Lara DR, Luckenbaugh DA, Busnello JV, Marca G, Cunha A, Souza DO, Zarate CA, Kapczinski F. A double-blind, randomized, placebo-controlled 4-week study on the efficacy and safety of the purinergic agents allopurinol and dipyridamole adjunctive to lithium in acute bipolar mania. The Journal of Clinical Psychiatry. 69: 1237-45. PMID 18681754 DOI: 10.4088/Jcp.V69N0806  0.328
2008 Machado-Vieira R, Salvadore G, Luckenbaugh DA, Manji HK, Zarate CA. Rapid onset of antidepressant action: a new paradigm in the research and treatment of major depressive disorder. The Journal of Clinical Psychiatry. 69: 946-58. PMID 18435563 DOI: 10.4088/Jcp.V69N0610  0.486
2008 Sanacora G, Zarate CA, Krystal JH, Manji HK. Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nature Reviews. Drug Discovery. 7: 426-37. PMID 18425072 DOI: 10.1038/Nrd2462  0.342
2008 Newberg AR, Catapano LA, Zarate CA, Manji HK. Neurobiology of bipolar disorder. Expert Review of Neurotherapeutics. 8: 93-110. PMID 18088203 DOI: 10.1586/14737175.8.1.93  0.347
2008 Maeng S, Zarate CA, Du J, Schloesser RJ, McCammon J, Chen G, Manji HK. Cellular mechanisms underlying the antidepressant effects of ketamine: role of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors. Biological Psychiatry. 63: 349-52. PMID 17643398 DOI: 10.1016/J.Biopsych.2007.05.028  0.4
2007 Angst J, Gamma A, Gerber-Werder R, Zarate CA, Manji HK. Does long-term medication with lithium, clozapine or antidepressants prevent or attenuate dementia in bipolar and depressed patients? International Journal of Psychiatry in Clinical Practice. 11: 2-8. PMID 24941269 DOI: 10.1080/13651500600810133  0.362
2007 Gould NF, Holmes MK, Fantie BD, Luckenbaugh DA, Pine DS, Gould TD, Burgess N, Manji HK, Zarate CA. Performance on a virtual reality spatial memory navigation task in depressed patients. The American Journal of Psychiatry. 164: 516-9. PMID 17329478 DOI: 10.1176/Ajp.2007.164.3.516  0.393
2007 Du J, Suzuki K, Wei Y, Wang Y, Blumenthal R, Chen Z, Falke C, Zarate CA, Manji HK. The anticonvulsants lamotrigine, riluzole, and valproate differentially regulate AMPA receptor membrane localization: relationship to clinical effects in mood disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 793-802. PMID 16936714 DOI: 10.1038/Sj.Npp.1301178  0.352
2007 Zarate CA, Charney DS, Manji HK. Searching for rational anti-N-methyl-D-aspartate treatment for depression: Reply [6] Archives of General Psychiatry. 64: 1100-1101. DOI: 10.1001/Archpsyc.64.9.1100  0.396
2006 Machado-Vieira R, Zarate CA, Manji HK. Emerging Novel Treatments for Severe Mood Disorders Involving Cellular Plasticity Cascades. Current Psychosis & Therapeutics Reports. 4: 181-190. PMID 25620894 DOI: 10.1007/Bf02629394  0.41
2006 Du J, Machado-Vieira R, Maeng S, Martinowich K, Manji HK, Zarate CA. Enhancing AMPA to NMDA throughput as a convergent mechanism for antidepressant action. Drug Discovery Today. Therapeutic Strategies. 3: 519-526. PMID 25411578 DOI: 10.1016/J.Ddstr.2006.11.012  0.316
2006 Perlis RH, Baker RW, Zarate CA, Brown EB, Schuh LM, Jamal HH, Tohen M. Olanzapine versus risperidone in the treatment of manic or mixed States in bipolar I disorder: a randomized, double-blind trial. The Journal of Clinical Psychiatry. 67: 1747-53. PMID 17196055 DOI: 10.4088/Jcp.V67N1112  0.323
2006 Mah L, Zarate CA, Singh J, Duan YF, Luckenbaugh DA, Manji HK, Drevets WC. Regional cerebral glucose metabolic abnormalities in bipolar II depression. Biological Psychiatry. 61: 765-75. PMID 17027930 DOI: 10.1016/J.Biopsych.2006.06.009  0.448
2006 Zarate CA, Singh JB, Carlson PJ, Brutsche NE, Ameli R, Luckenbaugh DA, Charney DS, Manji HK. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Archives of General Psychiatry. 63: 856-64. PMID 16894061 DOI: 10.1001/Archpsyc.63.8.856  0.472
2006 Carlson PJ, Singh JB, Zarate CA, Drevets WC, Manji HK. Neural circuitry and neuroplasticity in mood disorders: insights for novel therapeutic targets. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 22-41. PMID 16490411 DOI: 10.1016/J.Nurx.2005.12.009  0.381
2006 Zarate CA, Singh J, Manji HK. Cellular plasticity cascades: targets for the development of novel therapeutics for bipolar disorder. Biological Psychiatry. 59: 1006-20. PMID 16487491 DOI: 10.1016/J.Biopsych.2005.10.021  0.365
2006 Zarate CA, Singh JB, Quiroz JA, De Jesus G, Denicoff KK, Luckenbaugh DA, Manji HK, Charney DS. A double-blind, placebo-controlled study of memantine in the treatment of major depression. The American Journal of Psychiatry. 163: 153-5. PMID 16390905 DOI: 10.1176/Appi.Ajp.163.1.153  0.396
2006 Nugent AC, Milham MP, Bain EE, Mah L, Cannon DM, Marrett S, Zarate CA, Pine DS, Price JL, Drevets WC. Cortical abnormalities in bipolar disorder investigated with MRI and voxel-based morphometry. Neuroimage. 30: 485-97. PMID 16256376 DOI: 10.1016/J.Neuroimage.2005.09.029  0.335
2006 Kronstein PD, Zarate CA. The acute treatment of bipolar depression: Historically relevant and recent controlled trials Current Psychosis & Therapeutics Reports. 4: 151-158. DOI: 10.1007/Bf02629389  0.477
2005 Erickson K, Drevets WC, Clark L, Cannon DM, Bain EE, Zarate CA, Charney DS, Sahakian BJ. Mood-congruent bias in affective go/no-go performance of unmedicated patients with major depressive disorder. The American Journal of Psychiatry. 162: 2171-3. PMID 16263859 DOI: 10.1176/Appi.Ajp.162.11.2171  0.446
2005 Zhou R, Zarate CA, Manji HK. Identification of molecular mechanisms underlying mood stabilization through genome-wide gene expression profiling. The International Journal of Neuropsychopharmacology. 9: 263-6. PMID 16207389 DOI: 10.1017/S1461145705006176  0.307
2005 Zarate CA, Quiroz JA, Singh JB, Denicoff KD, De Jesus G, Luckenbaugh DA, Charney DS, Manji HK. An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression. Biological Psychiatry. 57: 430-2. PMID 15705360 DOI: 10.1016/J.Biopsych.2004.11.023  0.454
2005 Gould TD, Quiroz JA, Singh J, Zarate CA, Manji HK. Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers. Molecular Psychiatry. 9: 734-55. PMID 15136794 DOI: 10.1038/Sj.Mp.4001518  0.344
2005 Zarate CA, Singh JB, Carlson PJ, Manji HK. Molecular mechanisms of bipolar disorder Drug Discovery Today: Disease Mechanisms. 2: 435-445. DOI: 10.1016/J.Ddmec.2005.11.005  0.345
2004 Du J, Quiroz J, Yuan P, Zarate C, Manji HK. Bipolar disorder: involvement of signaling cascades and AMPA receptor trafficking at synapses. Neuron Glia Biology. 1: 231-43. PMID 18634600 DOI: 10.1017/S1740925X05000098  0.355
2004 Zarate CA, Payne JL, Singh J, Quiroz JA, Luckenbaugh DA, Denicoff KD, Charney DS, Manji HK. Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biological Psychiatry. 56: 54-60. PMID 15219473 DOI: 10.1016/J.Biopsych.2004.03.013  0.48
2004 Tohen M, Chengappa KN, Suppes T, Baker RW, Zarate CA, Bowden CL, Sachs GS, Kupfer DJ, Ghaemi SN, Feldman PD, Risser RC, Evans AR, Calabrese JR. Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone. The British Journal of Psychiatry : the Journal of Mental Science. 184: 337-45. PMID 15056579 DOI: 10.1192/Bjp.184.4.337  0.34
2004 McElroy SL, Zarate CA, Cookson J, Suppes T, Huffman RF, Greene P, Ascher J. A 52-week, open-label continuation study of lamotrigine in the treatment of bipolar depression. The Journal of Clinical Psychiatry. 65: 204-10. PMID 15003074 DOI: 10.4088/Jcp.V65N0210  0.451
2004 Zarate CA, Payne JL, Quiroz J, Sporn J, Denicoff KK, Luckenbaugh D, Charney DS, Manji HK. An open-label trial of riluzole in patients with treatment-resistant major depression. The American Journal of Psychiatry. 161: 171-4. PMID 14702270 DOI: 10.1176/Appi.Ajp.161.1.171  0.45
2004 Gould TD, Zarate CA, Manji HK. Glycogen synthase kinase-3: a target for novel bipolar disorder treatments. The Journal of Clinical Psychiatry. 65: 10-21. DOI: 10.1002/0470052171.Ch7  0.314
2003 Baldessarini RJ, Hennen J, Wilson M, Calabrese J, Chengappa R, Keck PE, McElroy SL, Sachs G, Vieta E, Welge JA, Yatham LN, Zarate CA, Baker RW, Tohen M. Olanzapine versus placebo in acute mania: treatment responses in subgroups. Journal of Clinical Psychopharmacology. 23: 370-6. PMID 12920413 DOI: 10.1097/01.Jcp.0000085410.08426.9A  0.304
2003 Tohen M, Ketter TA, Zarate CA, Suppes T, Frye M, Altshuler L, Zajecka J, Schuh LM, Risser RC, Brown E, Baker RW. Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study. The American Journal of Psychiatry. 160: 1263-71. PMID 12832240 DOI: 10.1176/Appi.Ajp.160.7.1263  0.31
2003 Manji HK, Quiroz JA, Sporn J, Payne JL, Denicoff K, A Gray N, Zarate CA, Charney DS. Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biological Psychiatry. 53: 707-42. PMID 12706957 DOI: 10.1016/S0006-3223(03)00117-3  0.417
2002 Tohen M, Baker RW, Altshuler LL, Zarate CA, Suppes T, Ketter TA, Milton DR, Risser R, Gilmore JA, Breier A, Tollefson GA. Olanzapine versus divalproex in the treatment of acute mania. The American Journal of Psychiatry. 159: 1011-7. PMID 12042191 DOI: 10.1176/Appi.Ajp.159.6.1011  0.35
2002 Tohen M, Chengappa KN, Suppes T, Zarate CA, Calabrese JR, Bowden CL, Sachs GS, Kupfer DJ, Baker RW, Risser RC, Keeter EL, Feldman PD, Tollefson GD, Breier A. Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy. Archives of General Psychiatry. 59: 62-9. PMID 11779284 DOI: 10.1001/Archpsyc.59.1.62  0.337
2000 Green AI, Tohen M, Patel JK, Banov M, DuRand C, Berman I, Chang H, Zarate C, Posener J, Lee H, Dawson R, Richards C, Cole JO, Schatzberg AF. Clozapine in the treatment of refractory psychotic mania. The American Journal of Psychiatry. 157: 982-6. PMID 10831480 DOI: 10.1176/Appi.Ajp.157.6.982  0.329
1999 Hirayasu Y, Shenton ME, Salisbury DF, Kwon JS, Wible CG, Fischer IA, Yurgelun-Todd D, Zarate C, Kikinis R, Jolesz FA, McCarley RW. Subgenual cingulate cortex volume in first-episode psychosis. The American Journal of Psychiatry. 156: 1091-3. PMID 10401458 DOI: 10.1176/Ajp.156.7.1091  0.337
1996 Pillay SS, Stoll AL, Weiss MK, Tohen M, Zarate CA, Banov MD, Cole JO. EEG abnormalities before clozapine therapy predict a good clinical response to clozapine. Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists. 8: 1-5. PMID 8743641 DOI: 10.3109/10401239609149083  0.31
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