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Brendan Patrick Orner, Ph.D., M.S., B.S. - Publications

Affiliations: 
2006-2012 Chemistry and Biological Chemistry Nanyang Technological University, Singapore, Singapore 
 2012- none Unemployed, Harlingen, TX, United States 
 2012-2016 Chemistry King's College London, London, UK 
Area:
Directed Evolution, Phage Display, Protein Engineering, Molecular Biology, Chemical Biology, Synthetic Biology, Medicinal Chemistry, Protein Chemistry, Organic Chemistry, Nanomaterials
Website:
http://orner-lab.appspot.com/
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Cornell TA, Orner BP. Medium throughput cage state stability screen of conditions for the generation of gold nanoparticles encapsulated within a mini-ferritin. Bioorganic & Medicinal Chemistry. 26: 5253-5258. PMID 29615283 DOI: 10.1016/J.Bmc.2018.03.036  0.373
2017 Zhang Y, Zhou J, Ardejani MS, Li X, Wang F, Orner BP. Designability of Aromatic Interaction Networks at E. coli Bacterioferritin B-Type Channels. Molecules (Basel, Switzerland). 22. PMID 29292762 DOI: 10.3390/Molecules22122184  0.797
2017 Cornell T, Ardejani MS, Fu J, Newland S, Zhang Y, Orner BP. A Structure-Based Assembly Screen of Protein Cage Libraries in Living Cells: Experimentally Repacking a Protein-Protein Interface to Recover Cage Formation in an Assembly-Frustrated Mutant. Biochemistry. PMID 29276894 DOI: 10.1021/Acs.Biochem.7B01000  0.804
2017 Cornell T, Srivastava Y, Jauch R, Fan R, Orner B. The Crystal Structure of a Maxi-/Mini-Ferritin Chimera Reveals Guiding Principles for the Assembly of Protein Cages. Biochemistry. PMID 28682051 DOI: 10.1021/Acs.Biochem.7B00312  0.74
2016 Hui Hiew S, Guerette PA, Zvarec OJ, Phillips M, Zhou F, Su H, Pervushin K, Orner BP, Miserez A. Modular peptides from the thermoplastic squid sucker ring teeth form amyloid-like cross-βsupramolecular networks. Acta Biomaterialia. PMID 27693688 DOI: 10.1016/J.Actbio.2016.09.040  0.434
2016 Zhang Y, Ardejani MS, Orner BP. Design and applications of protein cage-based nanomaterials. Chemistry, An Asian Journal. PMID 27432619 DOI: 10.1002/Asia.201600769  0.792
2015 Zhang Y, Wang L, Ardejani MS, Aris NF, Li X, Orner BP, Wang F. Mutagenesis Study to Disrupt Electrostatic Interactions on the Two-fold Symmetry Interface of E. coli Bacterioferritin. Journal of Biochemistry. PMID 26115686 DOI: 10.1093/Jb/Mvv065  0.783
2015 Cornell TA, Orner BP. Detection of protein cage assembly with bisarsenic fluorescent probes Methods in Molecular Biology. 1252: 79-89. PMID 25358775 DOI: 10.1007/978-1-4939-2131-7_8  0.459
2015 Ardejani MS, Orner BP. Computationally assisted engineering of protein cages Methods in Molecular Biology. 1252: 51-59. PMID 25358772 DOI: 10.1007/978-1-4939-2131-7_5  0.794
2013 Cornell TA, Fu J, Newland SH, Orner BP. Detection of specific protein-protein interactions in nanocages by engineering bipartite FlAsH binding sites Journal of the American Chemical Society. 135: 16618-16624. PMID 24164190 DOI: 10.1021/Ja4085034  0.487
2013 Ardejani MS, Orner BP. Obey the peptide assembly rules Science. 340: 561-562. PMID 23641105 DOI: 10.1126/Science.1237708  0.756
2013 Ardejani MS, Chok XL, Foo CJ, Orner BP. Complete shift of ferritin oligomerization toward nanocage assembly via engineered protein-protein interactions Chemical Communications. 49: 3528-3530. PMID 23511498 DOI: 10.1039/C3Cc40886H  0.794
2011 Zhang Y, Orner BP. Self-assembly in the ferritin nano-cage protein superfamily International Journal of Molecular Sciences. 12: 5406-5421. PMID 21954367 DOI: 10.3390/Ijms12085406  0.488
2011 Zhang Y, Fu J, Chee SY, Ang EXW, Orner BP. Rational disruption of the oligomerization of the mini-ferritin E. coli DPS through protein-protein interface mutation Protein Science. 20: 1907-1917. PMID 21898653 DOI: 10.1002/Pro.731  0.538
2011 Ardejani MS, Li NX, Orner BP. Stabilization of a protein nanocage through the plugging of a protein-protein interfacial water pocket Biochemistry. 50: 4029-4037. PMID 21488690 DOI: 10.1021/Bi200207W  0.798
2011 Dudak FC, Boyaci IH, Orner BP. The discovery of small-molecule mimicking peptides through phage display Molecules. 16: 774-789. PMID 21248663 DOI: 10.3390/Molecules16010774  0.348
2010 Li L, Orner BP, Huang T, Hinck AP, Kiessling LL. Peptide ligands that use a novel binding site to target both TGF-β receptors. Molecular Biosystems. 6: 2392-402. PMID 20890540 DOI: 10.1039/C0Mb00115E  0.76
2010 Fan R, Chew SW, Cheong VV, Orner BP. Fabrication of gold nanoparticles inside unmodified horse spleen apoferritin. Small (Weinheim An Der Bergstrasse, Germany). 6: 1483-7. PMID 20623737 DOI: 10.1002/Smll.201000457  0.682
2010 Zhang Y, Raudah S, Teo H, Teo GWS, Fan R, Sun X, Orner BP. Alanine-shaving mutagenesis to determine key interfacial residues governing the assembly of a nano-cage maxi-ferritin Journal of Biological Chemistry. 285: 12078-12086. PMID 20139406 DOI: 10.1074/Jbc.M109.092445  0.788
2010 Derda R, Musah S, Orner BP, Klim JR, Li L, Kiessling LL. High-throughput discovery of synthetic surfaces that support proliferation of pluripotent cells. Journal of the American Chemical Society. 132: 1289-95. PMID 20067240 DOI: 10.1021/Ja906089G  0.72
2009 Yu L, Yu PS, Yee Yen Mui E, McKelvie JC, Pham TPT, Yap YW, Wong WQ, Wu J, Deng W, Orner BP. Phage display screening against a set of targets to establish peptide-based sugar mimetics and molecular docking to predict binding site Bioorganic and Medicinal Chemistry. 17: 4825-4832. PMID 19447041 DOI: 10.1016/J.Bmc.2009.03.054  0.338
2009 Fan R, Boyle AL, Vee VC, See LN, Orner BP. A helix swapping study of two protein cages Biochemistry. 48: 5623-5630. PMID 19405543 DOI: 10.1021/Bi900387T  0.776
2007 Yue QF, Wan QW, Yan WY, Orner BP. Stem cells and combinatorial science Combinatorial Chemistry and High Throughput Screening. 10: 635-651. PMID 18045077 DOI: 10.2174/138620707782507322  0.3
2007 Derda R, Li L, Orner BP, Lewis RL, Thomson JA, Kiessling LL. Defined substrates for human embryonic stem cell growth identified from surface arrays. Acs Chemical Biology. 2: 347-55. PMID 17480050 DOI: 10.1021/Cb700032U  0.767
2006 Orner BP, Liu L, Murphy RM, Kiessling LL. Phage display affords peptides that modulate beta-amyloid aggregation. Journal of the American Chemical Society. 128: 11882-9. PMID 16953628 DOI: 10.1021/Ja0619861  0.533
2005 Yin H, Lee GI, Sedey KA, Kutzki O, Park HS, Orner BP, Ernst JT, Wang HG, Sebti SM, Hamilton AD. Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL. Journal of the American Chemical Society. 127: 10191-6. PMID 16028929 DOI: 10.1021/Ja050122X  0.768
2004 Orner BP, Derda R, Lewis RL, Thomson JA, Kiessling LL. Arrays for the combinatorial exploration of cell adhesion. Journal of the American Chemical Society. 126: 10808-9. PMID 15339142 DOI: 10.1021/Ja0474291  0.719
2002 Orner BP, Salvatella X, Sánchez Quesada J, De Mendoza J, Giralt E, Hamilton AD. De novo protein surface design: use of cation-pi interactions to enhance binding between an alpha-helical peptide and a cationic molecule in 50 % aqueous solution. Angewandte Chemie (International Ed. in English). 41: 117-9. PMID 12491457 DOI: 10.1002/1521-3773(20020104)41:1<117::Aid-Anie117>3.0.Co;2-J  0.501
2002 Kutzki O, Park HS, Ernst JT, Orner BP, Yin H, Hamilton AD. Development of a potent Bcl-x(L) antagonist based on alpha-helix mimicry. Journal of the American Chemical Society. 124: 11838-9. PMID 12358513 DOI: 10.1021/Ja026861K  0.78
2001 Orner BP, Ernst JT, Hamilton AD. Toward proteomimetics: terphenyl derivatives as structural and functional mimics of extended regions of an alpha-helix. Journal of the American Chemical Society. 123: 5382-3. PMID 11457415 DOI: 10.1021/Ja0025548  0.73
2001 Orner BP, Hamilton AD. The guanidinium group in molecular recognition: Design and synthetic approaches Journal of Inclusion Phenomena. 41: 141-147. DOI: 10.1023/A:1014433715641  0.399
2000 Linton BR, Carr AJ, Orner BP, Hamilton AD. A versatile one-Pot synthesis of 1,3-substituted guanidines from carbamoyl isothiocyanates The Journal of Organic Chemistry. 65: 1566-8. PMID 10814126 DOI: 10.1021/Jo991458Q  0.718
2000 Linton BR, Carr AJ, Orner BP, Hamilton AD. A versatile one-pot synthesis of 1,3-substituted guanidines from carbamoyl isothiocyanates Journal of Organic Chemistry. 65: 1566-1568. DOI: 10.1021/jo991458q  0.718
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