Geoffrey A. Kerchner - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 
 Stanford University, Palo Alto, CA 
Area:
Neurology and Neurological Sciences

35/105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rutledge J, Lehallier B, Zarifkar P, Losada PM, Shahid-Besanti M, Western D, Gorijala P, Ryman S, Yutsis M, Deutsch GK, Mormino E, Trelle A, Wagner AD, Kerchner GA, Tian L, et al. Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson's disease. Acta Neuropathologica. 147: 52. PMID 38467937 DOI: 10.1007/s00401-024-02706-0  0.414
2022 Wilson EN, Young CB, Ramos Benitez J, Swarovski MS, Feinstein I, Vandijck M, Le Guen Y, Kasireddy NM, Shahid M, Corso NK, Wang Q, Kennedy G, Trelle AN, Lind B, Channappa D, ... ... Kerchner GA, et al. Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer's disease. Alzheimer's Research & Therapy. 14: 172. PMID 36371232 DOI: 10.1186/s13195-022-01116-2  0.455
2021 Salloway S, Farlow M, McDade E, Clifford DB, Wang G, Llibre-Guerra JJ, Hitchcock JM, Mills SL, Santacruz AM, Aschenbrenner AJ, Hassenstab J, Benzinger TLS, Gordon BA, Fagan AM, Coalier KA, ... ... Kerchner GA, et al. A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease. Nature Medicine. PMID 34155411 DOI: 10.1038/s41591-021-01369-8  0.457
2021 Trelle AN, Carr VA, Wilson EN, Swarovski MS, Hunt MP, Toueg TN, Tran TT, Channappa D, Corso NK, Thieu MK, Jayakumar M, Nadiadwala A, Guo W, Tanner NJ, Bernstein JD, ... ... Kerchner GA, et al. Association of CSF Biomarkers with Hippocampal-dependent Memory in Preclinical Alzheimer Disease. Neurology. PMID 33408146 DOI: 10.1212/WNL.0000000000011477  0.507
2020 Trelle AN, Carr VA, Guerin SA, Thieu MK, Jayakumar M, Guo W, Nadiadwala A, Corso NK, Hunt MP, Litovsky CP, Tanner NJ, Deutsch GK, Bernstein JD, Harrison MB, Khazenzon AM, ... ... Kerchner GA, et al. Hippocampal and cortical mechanisms at retrieval explain variability in episodic remembering in older adults. Elife. 9. PMID 32469308 DOI: 10.7554/Elife.55335  0.55
2020 Trelle AN, Carr VA, Guerin SA, Thieu MK, Jayakumar M, Guo W, Nadiadwala A, Corso NK, Hunt MP, Litovsky CP, Tanner NJ, Deutsch GK, Bernstein JD, Harrison MB, Khazenzon AM, ... ... Kerchner GA, et al. Author response: Hippocampal and cortical mechanisms at retrieval explain variability in episodic remembering in older adults Elife. DOI: 10.7554/Elife.55335.Sa2  0.511
2019 La C, Linortner P, Bernstein JD, Ua Cruadhlaoich MAI, Fenesy M, Deutsch GK, Rutt BK, Tian L, Wagner AD, Zeineh M, Kerchner GA, Poston KL. Hippocampal CA1 subfield predicts episodic memory impairment in Parkinson's disease. Neuroimage. Clinical. 23: 101824. PMID 31054380 DOI: 10.1016/J.Nicl.2019.101824  0.548
2017 Carr VA, Bernstein JD, Favila SE, Rutt BK, Kerchner GA, Wagner AD. Individual differences in associative memory among older adults explained by hippocampal subfield structure and function. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078387 DOI: 10.1073/Pnas.1713308114  0.553
2016 Possin KL, Sanchez PE, Anderson-Bergman C, Fernandez R, Kerchner GA, Johnson ET, Davis A, Lo I, Bott NT, Kiely T, Fenesy MC, Miller BL, Kramer JH, Finkbeiner S. Cross-species translation of the Morris maze for Alzheimer's disease. The Journal of Clinical Investigation. PMID 26784542 DOI: 10.1172/Jci78464  0.419
2015 Yushkevich PA, Amaral RS, Augustinack JC, Bender AR, Bernstein JD, Boccardi M, Bocchetta M, Burggren AC, Carr VA, Chakravarty MM, Chételat G, Daugherty AM, Davachi L, Ding SL, Ekstrom A, ... ... Kerchner GA, et al. Quantitative comparison of 21 protocols for labeling hippocampal subfields and parahippocampal subregions in in vivo MRI: towards a harmonized segmentation protocol. Neuroimage. 111: 526-41. PMID 25596463 DOI: 10.1016/J.Neuroimage.2015.01.004  0.523
2014 Kerchner GA, Berdnik D, Shen JC, Bernstein JD, Fenesy MC, Deutsch GK, Wyss-Coray T, Rutt BK. APOE ε4 worsens hippocampal CA1 apical neuropil atrophy and episodic memory. Neurology. 82: 691-7. PMID 24453080 DOI: 10.1212/WNL.0000000000000154  0.369
2013 Kerchner GA, Bernstein JD, Fenesy MC, Deutsch GK, Saranathan M, Zeineh MM, Rutt BK. Shared vulnerability of two synaptically-connected medial temporal lobe areas to age and cognitive decline: a seven tesla magnetic resonance imaging study. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16666-72. PMID 24133269 DOI: 10.1523/Jneurosci.1915-13.2013  0.344
2013 Deutsch G, Fine E, Tan S, Llanes S, Karzmark P, Fenesy M, Hantke N, Zeifert P, Kerchner G. Predictors of activities of daily living in older adults: The Frontal Systems Behavior Scale (FrSBe) and neuropsychological test performance Alzheimers & Dementia. 9: 458. DOI: 10.1016/J.Jalz.2013.05.921  0.324
2013 Carr V, Bernstein J, Favila S, Wagner A, Kerchner G. IC-P-198: High-resolution imaging of medial temporal lobe subfield structure and function in mild cognitive impairment Alzheimer's & Dementia. 9: P111-P111. DOI: 10.1016/J.Jalz.2013.05.197  0.52
2012 Kerchner GA, Racine CA, Hale S, Wilheim R, Laluz V, Miller BL, Kramer JH. Cognitive processing speed in older adults: relationship with white matter integrity. Plos One. 7: e50425. PMID 23185621 DOI: 10.1371/Journal.Pone.0050425  0.379
2012 Kerchner GA, Deutsch GK, Zeineh M, Dougherty RF, Saranathan M, Rutt BK. Hippocampal CA1 apical neuropil atrophy and memory performance in Alzheimer's disease. Neuroimage. 63: 194-202. PMID 22766164 DOI: 10.1016/J.Neuroimage.2012.06.048  0.356
2012 Laforce R, Kerchner GA, Rabinovici GD, Fong JC, Miller BL, Seeley WW, Grinberg LT. A 44-year-old man with profound behavioural changes. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 39: 527-30. PMID 22728864 DOI: 10.1017/S0317167100014086  0.676
2012 Kerchner G, Deutsch G, Zeineh M, Dougherty R, Rutt B. Hippocampal CA1 Apical Neuropil Atrophy and Memory Performance in Alzheimer Disease (P04.223) Neurology. 78: P04.223-P04.223. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P04.223  0.345
2012 Carr V, Favila S, Bernstein J, Wagner A, Kerchner G. IC-P-091: Successful associative memory formation and retrieval in healthy older adults is associated with hippocampal subfield activation Alzheimer's & Dementia. 8: P53-P54. DOI: 10.1016/J.Jalz.2012.05.124  0.522
2011 Kerchner G, Deutsch G, Zeineh M, Rutt B. IC-P-127: Hippocampal microstructure and memory performance in Alzheimer's disease: A 7-Tesla MRI study Alzheimer's & Dementia. 7: S60-S61. DOI: 10.1016/J.Jalz.2011.05.092  0.327
2010 Kerchner GA, Hess CP, Hammond-Rosenbluth KE, Xu D, Rabinovici GD, Kelley DA, Vigneron DB, Nelson SJ, Miller BL. Hippocampal CA1 apical neuropil atrophy in mild Alzheimer disease visualized with 7-T MRI. Neurology. 75: 1381-7. PMID 20938031 DOI: 10.1212/Wnl.0B013E3181F736A1  0.567
2009 Menuz K, Kerchner GA, O'Brien JL, Nicoll RA. Critical role for TARPs in early development despite broad functional redundancy. Neuropharmacology. 56: 22-9. PMID 18634809 DOI: 10.1016/j.neuropharm.2008.06.037  0.704
2009 Kerchner GA, Nicoll RA. Silent synapses and the emergence of a postsynaptic mechanism for LTP (Nature Reviews Neuroscience (2008) 9, (813-825)) Nature Reviews Neuroscience. 10: 242. DOI: 10.1038/nrn2595  0.479
2008 Kerchner GA, Nicoll RA. Silent synapses and the emergence of a postsynaptic mechanism for LTP. Nature Reviews. Neuroscience. 9: 813-25. PMID 18854855 DOI: 10.1038/nrn2501  0.509
2002 Kerchner GA, Wilding TJ, Huettner JE, Zhuo M. Kainate receptor subunits underlying presynaptic regulation of transmitter release in the dorsal horn. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8010-7. PMID 12223554 DOI: 10.1523/Jneurosci.22-18-08010.2002  0.507
2002 Kerchner GA, Zhuo M. Presynaptic suppression of dorsal horn inhibitory transmission by mu-opioid receptors. Journal of Neurophysiology. 88: 520-2. PMID 12091574 DOI: 10.1152/Jn.2002.88.1.520  0.471
2002 Huettner JE, Kerchner GA, Zhuo M. Glutamate and the presynaptic control of spinal sensory transmission. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 8: 89-92. PMID 11954562 DOI: 10.1177/107385840200800204  0.485
2001 Kerchner GA, Wang GD, Qiu CS, Huettner JE, Zhuo M. Direct presynaptic regulation of GABA/glycine release by kainate receptors in the dorsal horn: an ionotropic mechanism. Neuron. 32: 477-88. PMID 11709158 DOI: 10.1016/S0896-6273(01)00479-2  0.474
2001 Wei F, Wang GD, Kerchner GA, Kim SJ, Xu HM, Chen ZF, Zhuo M. Genetic enhancement of inflammatory pain by forebrain NR2B overexpression. Nature Neuroscience. 4: 164-9. PMID 11175877 DOI: 10.1038/83993  0.492
2001 Kerchner GA, Wilding TJ, Li P, Zhuo M, Huettner JE. Presynaptic kainate receptors regulate spinal sensory transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 59-66. PMID 11150320 DOI: 10.1523/Jneurosci.21-01-00059.2001  0.497
2001 Kerchner GA, Wei F, Wang G, Kim SJ, Xu H, Robinson DA, Li P, Chen Z, Zhuo M. Reply To "Do 'smart' mice feel more pain, or are they just better learners?" Nature Neuroscience. 4: 453-454. DOI: 10.1038/87396  0.592
1999 Kerchner GA, Li P, Zhuo M. Speaking out of turn: a role for silent synapses in pain. Iubmb Life. 48: 251-6. PMID 10690634 DOI: 10.1080/713803505  0.499
1999 Li P, Kerchner GA, Sala C, Wei F, Huettner JE, Sheng M, Zhuo M. AMPA receptor-PDZ interactions in facilitation of spinal sensory synapses. Nature Neuroscience. 2: 972-7. PMID 10526335 DOI: 10.1038/14771  0.492
1999 Tang YP, Shimizu E, Dube GR, Rampon C, Kerchner GA, Zhuo M, Liu G, Tsien JZ. Genetic enhancement of learning and memory in mice. Nature. 401: 63-9. PMID 10485705 DOI: 10.1038/43432  0.513
1997 Sensi SL, Canzoniero LM, Yu SP, Ying HS, Koh JY, Kerchner GA, Choi DW. Measurement of intracellular free zinc in living cortical neurons: routes of entry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9554-64. PMID 9391010 DOI: 10.1523/Jneurosci.17-24-09554.1997  0.3
Low-probability matches (unlikely to be authored by this person)
2011 Kerchner GA. Ultra-high field 7T MRI: a new tool for studying Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 26: 91-5. PMID 21971453 DOI: 10.3233/JAD-2011-0023  0.297
2018 Sha SJ, Deutsch GK, Tian L, Richardson K, Coburn M, Gaudioso JL, Marcal T, Solomon E, Boumis A, Bet A, Mennes M, van Oort E, Beckmann CF, Braithwaite SP, Jackson S, ... ... Kerchner GA, et al. Safety, Tolerability, and Feasibility of Young Plasma Infusion in the Plasma for Alzheimer Symptom Amelioration Study: A Randomized Clinical Trial. Jama Neurology. PMID 30383097 DOI: 10.1001/Jamaneurol.2018.3288  0.292
2016 Wisse LE, Daugherty AM, Olsen RK, Berron D, Carr VA, Stark CE, Amaral RS, Amunts K, Augustinack JC, Bender AR, Bernstein JD, Boccardi M, Bocchetta M, Burggren A, Chakravarty MM, ... ... Kerchner GA, et al. A harmonized segmentation protocol for hippocampal and parahippocampal subregions: Why do we need one and what are the key goals? Hippocampus. PMID 27862600 DOI: 10.1002/Hipo.22671  0.291
2011 Kerchner GA. Amyloid imaging for Alzheimer's disease. Expert Opinion On Medical Diagnostics. 5: 527-38. PMID 23484750 DOI: 10.1517/17530059.2011.617365  0.29
2010 Kerchner GA. F5-02-03: Hippocampal neuropil atrophy in early Alzheimer's disease: A 7T MRI study Alzheimer's & Dementia. 6: S171-S171. DOI: 10.1016/j.jalz.2010.05.536  0.285
2013 Kerchner G, Bernstein J, Zeineh M, Saranathan M, Rutt B. IC-P-108: Structural covariance among synaptically connected, tau-susceptible subfields of the medial temporal lobe Alzheimer's & Dementia. 9: P63-P64. DOI: 10.1016/J.Jalz.2013.05.105  0.285
2014 Kerchner GA, Czirr E, Bernstein JD, Wyss-Coray T, Rutt BK. IC-P-166: CEREBROSPINAL FLUID TAU, BUT NOT AMYLOID, TRACKS ATROPHY IN ALZHEIMER-VULNERABLE HIPPOCAMPAL SUBFIELDS Alzheimer's & Dementia. 10: P93-P93. DOI: 10.1016/J.Jalz.2014.05.173  0.283
2012 Furst AJ, Kerchner GA. From Alois to Amyvid: seeing Alzheimer disease. Neurology. 79: 1628-9. PMID 22786589 DOI: 10.1212/WNL.0b013e3182662084  0.28
2012 Kerchner GA, Holbrook K. Novel presenilin-1 Y159F sequence variant associated with early-onset Alzheimer's disease. Neuroscience Letters. 531: 142-4. PMID 23123781 DOI: 10.1016/j.neulet.2012.10.037  0.279
2014 Kerchner GA, Fenesy MC, Johnson E, Bernstein J, Rutt BK, Possin KL. IC-P-167: ALZHEIMER-VULNERABLE HIPPOCAMPAL SUBFIELDS PREDICT NAVIGATIONAL PERFORMANCE IN OLDER ADULTS Alzheimer's & Dementia. 10: P93-P93. DOI: 10.1016/j.jalz.2014.05.174  0.278
2017 Wildsmith KR, Bohorquez SS, Manser PT, Höglund K, Blennow K, van der Brug MP, Bengtsson T, Marik J, Ayalon G, Ward M, Kerchner GA, Weimer R. [P2-367]: CROSS-SECTIONAL CORRELATION BETWEEN GTP1-TAU-PET AND CSF TAU AS MEASURES OF TAU BURDEN IN ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P766-P766. DOI: 10.1016/J.Jalz.2017.06.1022  0.266
2020 Poston KL, Ua Cruadhlaoich MAI, Santoso LF, Bernstein JD, Liu T, Wang Y, Rutt B, Kerchner GA, Zeineh MM. Substantia Nigra Volume Dissociates Bradykinesia and Rigidity from Tremor in Parkinson's Disease: A 7 Tesla Imaging Study. Journal of Parkinson's Disease. 10: 591-604. PMID 32250317 DOI: 10.3233/Jpd-191890  0.263
2000 Kerchner GA, Canzoniero LM, Yu SP, Ling C, Choi DW. Zn2+ current is mediated by voltage-gated Ca2+ channels and enhanced by extracellular acidity in mouse cortical neurones. The Journal of Physiology. 528: 39-52. PMID 11018104 DOI: 10.1111/J.1469-7793.2000.00039.X  0.262
2016 Wisse LEM, Daugherty AM, Amaral RSC, Berron D, Carr VA, Ekstrom AD, Kanel P, Kerchner GA, Mueller SG, Pluta J, Stark CE, Steve T, Wang L, Yassa MA, Yushkevich PA, et al. A Harmonized Protocol For Medial Temporal Lobe Subfield Segmentation: Initial Results Of The 3-Tesla Protocol For The Hippocampal Body Alzheimers & Dementia. 12: 631. DOI: 10.1016/J.Jalz.2016.06.1265  0.256
2015 Wisse L, Daugherty AM, Joie RL, Insausti R, Yassa MA, Carr VA, Ekstrom AD, Kerchner GA, Mueller SG, Stark CE, Wang L, Yushkevich PA. Towards a harmonized protocol for hippocampal subfield segmentation: An update Alzheimers & Dementia. 11: 881. DOI: 10.1016/J.Jalz.2015.08.087  0.25
2012 Kerchner G, Holbrook K, Deutsch G. Novel presenilin-1 mutation causing familial early-onset Alzheimer's disease without motor signs Alzheimers & Dementia. 8: 668. DOI: 10.1016/J.Jalz.2012.05.1806  0.248
2006 Kerchner GA, Smith W, Lawton MT, Singh V. Co-occurrence of a cavernous malformation and contralateral moyamoya. Neurology. 66: 1601-2. PMID 16717235 DOI: 10.1212/01.wnl.0000216268.11999.ed  0.246
2011 Kerchner GA, Tartaglia MC, Boxer A. Abhorring the vacuum: use of Alzheimer’s disease medications in frontotemporal dementia. Expert Review of Neurotherapeutics. 11: 709-17. PMID 21728274 DOI: 10.1586/ern.11.6  0.243
2014 Lopez J, Lomen-Hoerth C, Deutsch GK, Kerchner GA, Koshy A. Influenza-associated global amnesia and hippocampal imaging abnormality. Neurocase. 20: 446-51. PMID 23697757 DOI: 10.1080/13554794.2013.791864  0.241
2011 Kerchner G, Dougherty R. P4-058: Ultra-high field 7-Tesla hippocampal imaging: A semi-automated method for measuring stratal width Alzheimer's & Dementia. 7: S718-S719. DOI: 10.1016/J.Jalz.2011.05.2078  0.239
2014 Koh W, Pan W, Gawad C, Fan HC, Kerchner GA, Wyss-Coray T, Blumenfeld YJ, El-Sayed YY, Quake SR. Noninvasive in vivo monitoring of tissue-specific global gene expression in humans. Proceedings of the National Academy of Sciences of the United States of America. 111: 7361-6. PMID 24799715 DOI: 10.1073/Pnas.1405528111  0.228
2014 Saranathan M, Tourdias T, Kerr AB, Bernstein JD, Kerchner GA, Han MH, Rutt BK. Optimization of magnetization-prepared 3-dimensional fluid attenuated inversion recovery imaging for lesion detection at 7 T. Investigative Radiology. 49: 290-8. PMID 24566291 DOI: 10.1097/Rli.0000000000000041  0.225
1998 Yu SP, Kerchner GA. Endogenous voltage-gated potassium channels in human embryonic kidney (HEK293) cells. Journal of Neuroscience Research. 52: 612-7. PMID 9632317 DOI: 10.1002/(SICI)1097-4547(19980601)52:5<612::AID-JNR13>3.0.CO;2-3  0.209
2015 Kerchner GA, Dougherty RF, Dagum P. O4-03-02: Unobtrusive neuropsychological monitoring from smart phone use behavior Alzheimer's & Dementia. 11: P272-P273. DOI: 10.1016/J.Jalz.2015.07.358  0.185
2021 Ayalon G, Lee SH, Adolfsson O, Foo-Atkins C, Atwal JK, Blendstrup M, Booler H, Bravo J, Brendza R, Brunstein F, Chan R, Chandra P, Couch JA, Datwani A, Demeule B, ... ... Kerchner GA, et al. Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease. Science Translational Medicine. 13. PMID 33980574 DOI: 10.1126/scitranslmed.abb2639  0.171
2010 Kerchner GA, Hess CP, Hammond-Rosenbluth K, Xu D, Kelley DA, Vigneron DP, Nelson SJ, Miller BL. IC-03-04: Hippocampal neuropil atrophy in early Alzheimer's disease: A 7T MRI study Alzheimer's & Dementia. 6: S59-S60. DOI: 10.1016/j.jalz.2010.05.166  0.16
2014 Kerchner GA, Czirr E, Bernstein JD, Wyss-Coray T, Rutt BK. P1-265: CEREBROSPINAL FLUID TAU, BUT NOT AMYLOID, TRACKS ATROPHY IN ALZHEIMER'S-VULNERABLE HIPPOCAMPAL SUBFIELDS Alzheimer's & Dementia. 10: P406-P406. DOI: 10.1016/j.jalz.2014.05.505  0.156
2019 Teng E, Ward M, Manser PT, Sanabria-Bohorquez S, Ray RD, Wildsmith KR, Baker S, Kerchner GA, Weimer RM. Cross-sectional associations between [F]GTP1 tau PET and cognition in Alzheimer's disease. Neurobiology of Aging. 81: 138-145. PMID 31280117 DOI: 10.1016/j.neurobiolaging.2019.05.026  0.152
2024 Plastini MJ, Abdelnour C, Young CB, Wilson EN, Shahid-Besanti M, Lamoureux J, Andreasson KI, Kerchner GA, Montine TJ, Henderson VW, Poston KL. Multiple biomarkers improve diagnostic accuracy across Lewy body and Alzheimer's disease spectra. Annals of Clinical and Translational Neurology. PMID 38436140 DOI: 10.1002/acn3.52034  0.15
2019 Blennow K, Chen C, Cicognola C, Wildsmith KR, Manser PT, Bohorquez SMS, Zhang Z, Xie B, Peng J, Hansson O, Kvartsberg H, Portelius E, Zetterberg H, Lashley T, Brinkmalm G, ... Kerchner GA, et al. Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology. Brain : a Journal of Neurology. PMID 31834365 DOI: 10.1093/Brain/Awz346  0.148
2022 Teng E, Manser PT, Pickthorn K, Brunstein F, Blendstrup M, Sanabria Bohorquez S, Wildsmith KR, Toth B, Dolton M, Ramakrishnan V, Bobbala A, Sikkes SAM, Ward M, Fuji RN, Kerchner GA. Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease: A Randomized Clinical Trial. Jama Neurology. PMID 35696185 DOI: 10.1001/jamaneurol.2022.1375  0.141
2021 Teng E, Manser PT, Sanabria Bohorquez S, Wildsmith KR, Pickthorn K, Baker SL, Ward M, Kerchner GA, Weimer RM. Baseline [F]GTP1 tau PET imaging is associated with subsequent cognitive decline in Alzheimer's disease. Alzheimer's Research & Therapy. 13: 196. PMID 34852837 DOI: 10.1186/s13195-021-00937-x  0.139
2014 Kerchner GA, Fenesy MC, Johnson E, Bernstein J, Rutt BK, Possin KL. O2-10-06: ALZHEIMER'S-VULNERABLE HIPPOCAMPAL SUBFIELDS PREDICT NAVIGATIONAL PERFORMANCE IN OLDER ADULTS Alzheimer's & Dementia. 10: P188-P188. DOI: 10.1016/j.jalz.2014.04.215  0.139
2022 Mazer NA, Hofmann C, Lott D, Gieschke R, Klein G, Boess F, Grimm HP, Kerchner GA, Baudler-Klein M, Smith J, Doody RS. Development of a quantitative semi-mechanistic model of Alzheimer's disease based on the amyloid/tau/neurodegeneration framework (the Q-ATN model). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36454709 DOI: 10.1002/alz.12877  0.138
2019 Sanabria Bohórquez S, Marik J, Ogasawara A, Tinianow JN, Gill HS, Barret O, Tamagnan G, Alagille D, Ayalon G, Manser P, Bengtsson T, Ward M, Williams SP, Kerchner GA, Seibyl JP, et al. [F]GTP1 (Genentech Tau Probe 1), a radioligand for detecting neurofibrillary tangle tau pathology in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31254035 DOI: 10.1007/S00259-019-04399-0  0.136
2019 Klein G, Delmar P, Voyle N, Rehal S, Hofmann C, Abi-Saab D, Andjelkovic M, Ristic S, Wang G, Bateman R, Kerchner GA, Baudler M, Fontoura P, Doody R. Gantenerumab reduces amyloid-β plaques in patients with prodromal to moderate Alzheimer's disease: a PET substudy interim analysis. Alzheimer's Research & Therapy. 11: 101. PMID 31831056 DOI: 10.1186/S13195-019-0559-Z  0.126
1984 Mendelsohn LG, Kerchner GA, Kalra V, Zimmerman DM, Leander JD. Phencyclidine receptors in rat brain cortex. Biochemical Pharmacology. 33: 3529-35. PMID 6095851 DOI: 10.1016/0006-2952(84)90133-3  0.125
2010 Kerchner GA, Boxer AL. Bapineuzumab. Expert Opinion On Biological Therapy. 10: 1121-30. PMID 20497044 DOI: 10.1517/14712598.2010.493872  0.122
2014 Henderson VW, Kerchner GA. Alzheimer's Disease Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00017-9  0.122
1988 Mendelsohn LG, Smith MC, Lucaites VL, Kerchner GA, Ghetti B. Autoradiographic localization of insulin-like growth factor II receptors in cerebellar cortex of weaver and Purkinje cell degeneration mutant mice. Brain Research. 458: 361-6. PMID 2850081 DOI: 10.1016/0006-8993(88)90479-9  0.121
2024 Pagano G, Taylor KI, Anzures Cabrera J, Simuni T, Marek K, Postuma RB, Pavese N, Stocchi F, Brockmann K, Svoboda H, Trundell D, Monnet A, Doody R, Fontoura P, Kerchner GA, et al. Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson's disease. Nature Medicine. PMID 38622249 DOI: 10.1038/s41591-024-02886-y  0.12
2000 Lobner D, Canzoniero LM, Manzerra P, Gottron F, Ying H, Knudson M, Tian M, Dugan LL, Kerchner GA, Sheline CT, Korsmeyer SJ, Choi DW. Zinc-induced neuronal death in cortical neurons. Cellular and Molecular Biology (Noisy-Le-Grand, France). 46: 797-806. PMID 10875441  0.117
2024 Sanabria Bohórquez SM, Baker S, Manser PT, Tonietto M, Galli C, Wildsmith KR, Zou Y, Kerchner GA, Weimer R, Teng E. Evaluation of partial volume correction and analysis of longitudinal [F]GTP1 tau PET imaging in Alzheimer's disease using linear mixed-effects models. Frontiers in Neuroimaging. 3: 1355402. PMID 38606196 DOI: 10.3389/fnimg.2024.1355402  0.11
1988 Smith M, Clemens J, Kerchner GA, Mendelsohn LG. The insulin-like growth factor-II (IGF-II) receptor of rat brain: regional distribution visualized by autoradiography. Brain Research. 445: 241-6. PMID 2967099 DOI: 10.1016/0006-8993(88)91185-7  0.1
2023 Welsh-Bohmer KA, Kerchner GA, Dhadda S, Garcia M, Miller DS, Natanegara F, Raket LL, Robieson W, Siemers ER, Carrillo MC, Weber CJ. Decision making in clinical trials: Interim analyses, innovative design, and biomarkers. Alzheimer's & Dementia (New York, N. Y.). 9: e12421. PMID 37867532 DOI: 10.1002/trc2.12421  0.099
2016 Bohorquez SS, Barret O, Tamagnan G, Alagille D, Marik J, Ayalon G, Bengtsson T, de Crespigny A, Jennings D, Seibyl JP, Marek K, Weimer R, Kerchner GA. P4-351: Evaluation of TAU Burden in a Cross-Sectional Cohort of Alzheimer’S Disease Subjects Using [18 F]GTP1 (GENENTECH TAU PROBE 1) Alzheimer's & Dementia. 12: P1172-P1172. DOI: 10.1016/J.Jalz.2016.07.096  0.095
1976 Freudenthal RI, Leber AP, Emmerling DC, Kerchner GA, Ovejera AA. Comparison of the drug metabolizing enzymes in the liver and kidneys from homozygous nude swiss, heterozygous normal swiss, homozygous normal Swiss and DBA/2 mice. Research Communications in Chemical Pathology and Pharmacology. 15: 267-78. PMID 981786  0.091
1985 Mendelsohn LG, Kalra V, Johnson BG, Kerchner GA. Sigma opioid receptor: characterization and co-identity with the phencyclidine receptor. The Journal of Pharmacology and Experimental Therapeutics. 233: 597-602. PMID 2989489  0.09
2022 Pagano G, Taylor KI, Anzures-Cabrera J, Marchesi M, Simuni T, Marek K, Postuma RB, Pavese N, Stocchi F, Azulay JP, Mollenhauer B, López-Manzanares L, Russell DS, Boyd JT, Nicholas AP, ... ... Kerchner GA, et al. Trial of Prasinezumab in Early-Stage Parkinson's Disease. The New England Journal of Medicine. 387: 421-432. PMID 35921451 DOI: 10.1056/NEJMoa2202867  0.087
2019 Klein G, Delmar P, Kerchner GA, Hofmann C, Abi-Saab D, Ristic S, Rehal S, Voyle N, Baudler M, Fontoura P, Doody R. DT-01-02: CONTINUED LARGE AMYLOID PET REDUCTIONS AT 36 MONTHS IN THE GANTENERUMAB OPEN-LABEL EXTENSION STUDIES Alzheimer's & Dementia. 15: P1484-P1485. DOI: 10.1016/j.jalz.2019.08.005  0.086
2020 Kerchner GA, Filippi M. Aβ-PET pathology accumulation index: Ready for the clinic? Neurology. PMID 33077546 DOI: 10.1212/WNL.0000000000011060  0.083
1985 Mendelsohn LG, Kerchner GA, Culwell M, Ades EW. Immunoregulation by opioid peptides: I. Absence of classical opioid receptor on human mononuclear cells. Journal of Clinical & Laboratory Immunology. 16: 125-9. PMID 2993625  0.082
2022 Katz JS, Rothstein JD, Cudkowicz ME, Genge A, Oskarsson B, Hains AB, Chen C, Galanter J, Burgess BL, Cho W, Kerchner GA, Yeh FL, Ghosh AS, Cheeti S, Brooks L, et al. A Phase 1 study of GDC-0134, a dual leucine zipper kinase inhibitor, in ALS. Annals of Clinical and Translational Neurology. PMID 35014217 DOI: 10.1002/acn3.51491  0.075
2017 Kerchner GA, Ayalon G, Brunstein F, Chandra P, Datwani A, Fuji RN, Manser PT, Vaze A, Ward M, Wildsmith KR, Foo-Atkins C. [O2-17-03]: A PHASE I STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF RO7105705 IN HEALTHY VOLUNTEERS AND PATIENTS WITH MILD-TO-MODERATE AD Alzheimer's & Dementia. 13: P601-P601. DOI: 10.1016/j.jalz.2017.07.243  0.073
2022 Wang G, Li Y, Xiong C, McDade E, Clifford DB, Mills SL, Santacruz AM, Aschenbrenner AJ, Hassenstab J, Benzinger TLS, Gordon BA, Fagan AM, Coalier KA, Libre-Guerra JJ, McCullough A, ... ... Kerchner GA, et al. Evaluation of dose-dependent treatment effects after mid-trial dose escalation in biomarker, clinical, and cognitive outcomes for gantenerumab or solanezumab in dominantly inherited Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 14: e12367. PMID 36348972 DOI: 10.1002/dad2.12367  0.071
2021 Dolton MJ, Chesterman A, Moein A, Sink KM, Waitz A, Blondeau K, Kerchner GA, Hu N, Brooks L, Wetzel-Smith MK, Roden A, Deshmukh A, Peng K, Carrasco-Triguero M, Smith J, et al. Safety, Tolerability and Pharmacokinetics of High-Volume Subcutaneous Crenezumab, With and Without Recombinant Human Hyaluronidase in Healthy Volunteers. Clinical Pharmacology and Therapeutics. PMID 34347883 DOI: 10.1002/cpt.2385  0.068
2017 Chang D, Nalls MA, Hallgrímsdóttir IB, Hunkapiller J, van der Brug M, Cai F, Kerchner GA, Ayalon G, Bingol B, Sheng M, Hinds D, Behrens TW, Singleton AB, et al. A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. Nature Genetics. PMID 28892059 DOI: 10.1038/Ng.3955  0.067
2019 Delmar P, Kerchner GA, Wang G, Bateman R, Klein G, Rehal S, Voyle N, Andjelkovic M, Abi-Saab D, Bullain SS, Ristic S, Baudler M, Fontoura P, Doody R. O3-10-01: CORRELATION BETWEEN AMYLOID REDUCTION AND CLINICAL OUTCOMES: EXPLORATORY ANALYSES FROM THE GANTENERUMAB SCARLET ROAD AND MARGUERITE ROAD OPEN-LABEL EXTENSION STUDIES Alzheimer's & Dementia. 15: P908-P909. DOI: 10.1016/J.Jalz.2019.06.4678  0.06
1985 Su KS, Campanale KM, Mendelsohn LG, Kerchner GA, Gries CL. Nasal delivery of polypeptides I: nasal absorption of enkephalins in rats. Journal of Pharmaceutical Sciences. 74: 394-8. PMID 3889275 DOI: 10.1002/jps.2600740406  0.04
1983 Kerchner GA, Geary LE. Studies on the transport of enkephalin-like oligopeptides in rat intestinal mucosa. The Journal of Pharmacology and Experimental Therapeutics. 226: 33-8. PMID 6345754  0.037
2014 Koh W, Pan W, Gawad C, Fan HC, Kerchner GA, Wyss-Coray T, Blumenfeld YJ, El-Sayed YY, Quake SR. Noninvasive in vivo monitoring of tissue-specific global gene expression in humans (Proceedings of the National Academy of Sciences of the United States of America (2014) 111 (7361-7366) DOI: 10.1073/pnas.1405528111) Proceedings of the National Academy of Sciences of the United States of America. 111: 11223. DOI: 10.1073/pnas.1412162111  0.033
2012 Kerchner GA. New lithium battery dangerous goods regulations on the horizon: The regulator's and industry's perspective 29th International Battery Seminar and Exhibit 2012: Primary and Secondary Batteries - Other Technologies. 1: 267-278.  0.029
1975 Leber P, Kerchner GA, Frendenthal RI. Benzopyrene metabolism and cytochrome P 450 determinations in hepatic microsomes of Tupaia Pharmacologist. 17: No.157.  0.021
2008 Kerchner GA. PRBA 2007-2008 regulatory activities on battery safety Florida Educational Seminars, Inc. - 25th International Battery Seminar and Exhibit 2008: Primary and Secondary Batteries - Small Fuel Cells - Other Technologies. 1: 198-213.  0.019
1994 Ramsey RS, Kerchner GA, Cadet J. Micellar electrokinetic capillary chromatography of nucleic acid constituents and dinucleoside monophosphate photoproducts Hrc (J.High Resolut.Chromatogr.). 17: 4-8.  0.014
2011 Kerchner GA. Battery safety and product stewardship a 20 year perspective Battery Power 2011. 317-327.  0.011
2013 Kerchner GA. Regulatory and legislative challenges facing the rechargeable battery industry over the next five years 30th International Battery Seminar and Exhibit 2013: Primary and Secondary Batteries - Other Technologies. 1: 145-154.  0.011
2014 Kerchner GA. The very long and very winding road to new lithium battery Battery Power Conference 2014. 16-25.  0.01
2011 Kerchner GA. Regulatory and legislative update 28th International Battery Seminar and Exhibit 2011. 1: 146-162.  0.01
1977 Freudenthal RI, Kerchner GA, Persing RL, Baumel I, Baron RL. Subacute toxicity of ethylenebisisothiocyanate sulfide in the laboratory rat. Journal of Toxicology and Environmental Health. 2: 1067-78. PMID 864780 DOI: 10.1080/15287397709529504  0.01
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