James R. Howe - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Glutamate Receptors

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Zhang W, Eibl C, Weeks AM, Riva I, Li YJ, Plested AJR, Howe JR. Unitary Properties of AMPA Receptors with Reduced Desensitization. Biophysical Journal. PMID 28863863 DOI: 10.1016/j.bpj.2017.07.030  1
2016 Straub C, Noam Y, Nomura T, Yamasaki M, Yan D, Fernandes HB, Zhang P, Howe JR, Watanabe M, Contractor A, Tomita S. Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor. Cell Reports. PMID 27346345 DOI: 10.1016/j.celrep.2016.05.093  1
2015 Howe JR. Auxiliary subunits highlight a role for the LBD-TMD linkers in glutamate receptor desensitization. The Journal of Physiology. 593: 4813-4. PMID 26576775 DOI: 10.1113/JP271434  1
2015 Howe JR. Modulation of non-NMDA receptor gating by auxiliary subunits. The Journal of Physiology. 593: 61-72. PMID 25556788 DOI: 10.1113/jphysiol.2014.273904  1
2014 MacLean DM, Ramaswamy SS, Du M, Howe JR, Jayaraman V. Stargazin promotes closure of the AMPA receptor ligand-binding domain. The Journal of General Physiology. 144: 503-12. PMID 25422502 DOI: 10.1085/jgp.201411287  1
2014 Zhang W, Devi SP, Tomita S, Howe JR. Auxiliary proteins promote modal gating of AMPA- and kainate-type glutamate receptors. The European Journal of Neuroscience. 39: 1138-47. PMID 24712993 DOI: 10.1111/ejn.12519  1
2013 Howe JR. CrossTalk proposal: TARPs modulate AMPA receptor gating transitions. The Journal of Physiology. 591: 1581-3; discussion 1. PMID 23547186 DOI: 10.1113/jphysiol.2012.247486  1
2013 Howe JR. Rebuttal from James Howe Journal of Physiology. 591: 1587. DOI: 10.1113/jphysiol.2012.250449  1
2011 Straub C, Zhang W, Howe JR. Neto2 modulation of kainate receptors with different subunit compositions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8078-82. PMID 21632929 DOI: 10.1523/JNEUROSCI.0024-11.2011  1
2010 O'Dorisio TM, Krutzik SR, Woltering EA, Lindholm E, Joseph S, Gandolfi AE, Wang YZ, Boudreaux JP, Vinik AI, Go VL, Howe JR, Halfdanarson T, O'Dorisio MS, Mamikunian G. Development of a highly sensitive and specific carboxy-terminal human pancreastatin assay to monitor neuroendocrine tumor behavior. Pancreas. 39: 611-6. PMID 20124939 DOI: 10.1097/MPA.0b013e3181c68d7a  0.56
2009 Zhang W, St-Gelais F, Grabner CP, Trinidad JC, Sumioka A, Morimoto-Tomita M, Kim KS, Straub C, Burlingame AL, Howe JR, Tomita S. A transmembrane accessory subunit that modulates kainate-type glutamate receptors. Neuron. 61: 385-96. PMID 19217376 DOI: 10.1016/j.neuron.2008.12.014  1
2009 Morimoto-Tomita M, Zhang W, Straub C, Cho CH, Kim KS, Howe JR, Tomita S. Autoinactivation of neuronal AMPA receptors via glutamate-regulated TARP interaction. Neuron. 61: 101-12. PMID 19146816 DOI: 10.1016/j.neuron.2008.11.009  1
2008 Zhang W, Howe JR, Popescu GK. Distinct gating modes determine the biphasic relaxation of NMDA receptor currents. Nature Neuroscience. 11: 1373-5. PMID 18953348 DOI: 10.1038/nn.2214  1
2008 Zhang W, Cho Y, Lolis E, Howe JR. Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 932-43. PMID 18216201 DOI: 10.1523/JNEUROSCI.3309-07.2008  1
2007 Cho CH, St-Gelais F, Zhang W, Tomita S, Howe JR. Two families of TARP isoforms that have distinct effects on the kinetic properties of AMPA receptors and synaptic currents. Neuron. 55: 890-904. PMID 17880893 DOI: 10.1016/j.neuron.2007.08.024  1
2006 Howe JR. Desensitization at the interface. Acs Chemical Biology. 1: 623-6. PMID 17168566 DOI: 10.1021/cb6004382  1
2006 Sheridan DL, Robert A, Cho CH, Howe JR, Hughes TE. Regions of alpha-amino-5-methyl-3-hydroxy-4-isoxazole propionic acid receptor subunits that are permissive for the insertion of green fluorescent protein. Neuroscience. 141: 837-49. PMID 16765522 DOI: 10.1016/j.neuroscience.2006.04.052  1
2006 Zhang W, Robert A, Vogensen SB, Howe JR. The relationship between agonist potency and AMPA receptor kinetics. Biophysical Journal. 91: 1336-46. PMID 16731549 DOI: 10.1529/biophysj.106.084426  1
2005 Tomita S, Adesnik H, Sekiguchi M, Zhang W, Wada K, Howe JR, Nicoll RA, Bredt DS. Stargazin modulates AMPA receptor gating and trafficking by distinct domains. Nature. 435: 1052-8. PMID 15858532 DOI: 10.1038/nature03624  1
2005 Robert A, Armstrong N, Gouaux JE, Howe JR. AMPA receptor binding cleft mutations that alter affinity, efficacy, and recovery from desensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3752-62. PMID 15829627 DOI: 10.1523/JNEUROSCI.0188-05.2005  1
2004 Popescu G, Robert A, Howe JR, Auerbach A. Reaction mechanism determines NMDA receptor response to repetitive stimulation. Nature. 430: 790-3. PMID 15306812 DOI: 10.1038/nature02775  0.36
2004 Klein RM, Howe JR. Effects of the lurcher mutation on GluR1 desensitization and activation kinetics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4941-51. PMID 15163686 DOI: 10.1523/JNEUROSCI.0660-04.2004  1
2003 Robert A, Howe JR. How AMPA receptor desensitization depends on receptor occupancy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 847-58. PMID 12574413  1
2002 Robert A, Hyde R, Hughes TE, Howe JR. The expression of dominant-negative subunits selectively suppresses neuronal AMPA and kainate receptors. Neuroscience. 115: 1199-210. PMID 12453491 DOI: 10.1016/S0306-4522(02)00534-1  1
2002 Sheridan DL, Berlot CH, Robert A, Inglis FM, Jakobsdottir KB, Howe JR, Hughes TE. A new way to rapidly create functional, fluorescent fusion proteins: random insertion of GFP with an in vitro transposition reaction. Bmc Neuroscience. 3: 7. PMID 12086589 DOI: 10.1186/1471-2202-3-7  1
2002 Schmauss C, Howe JR. RNA editing of neurotransmitter receptors in the mammalian brain. Science's Stke : Signal Transduction Knowledge Environment. 2002: pe26. PMID 12023441 DOI: 10.1126/stke.2002.133.pe26  1
2002 Wall MJ, Robert A, Howe JR, Usowicz MM. The speeding of EPSC kinetics during maturation of a central synapse. The European Journal of Neuroscience. 15: 785-97. PMID 11906520 DOI: 10.1046/j.1460-9568.2002.01910.x  1
2001 Robert A, Irizarry SN, Hughes TE, Howe JR. Subunit interactions and AMPA receptor desensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5574-86. PMID 11466429  1
2000 Goldin AL, Barchi RL, Caldwell JH, Hofmann F, Howe JR, Hunter JC, Kallen RG, Mandel G, Meisler MH, Netter YB, Noda M, Tamkun MM, Waxman SG, Wood JN, Catterall WA. Nomenclature of voltage-gated sodium channels. Neuron. 28: 365-8. PMID 11144347  1
2000 Smith TC, Howe JR. Concentration-dependent substate behavior of native AMPA receptors. Nature Neuroscience. 3: 992-7. PMID 11017171 DOI: 10.1038/79931  1
2000 Smith TC, Wang LY, Howe JR. Heterogeneous conductance levels of native AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2073-85. PMID 10704481  1
2000 Robert A, Howe JR, Waxman SG. Development of glutamatergic synaptic activity in cultured spinal neurons. Journal of Neurophysiology. 83: 659-70. PMID 10669482  1
1999 Smith TC, Wang LY, Howe JR. Distinct kainate receptor phenotypes in immature and mature mouse cerebellar granule cells. The Journal of Physiology. 517: 51-8. PMID 10226148 DOI: 10.1111/j.1469-7793.1999.0051z.x  1
1999 Howe JR. How glutamate receptors are built Neuroscientist. 5: 311-323. DOI: 10.1177/107385849900500517  1
1998 Cummins TR, Howe JR, Waxman SG. Slow closed-state inactivation: a novel mechanism underlying ramp currents in cells expressing the hNE/PN1 sodium channel. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9607-19. PMID 9822722  1
1998 Pemberton KE, Belcher SM, Ripellino JA, Howe JR. High-affinity kainate-type ion channels in rat cerebellar granule cells. The Journal of Physiology. 510: 401-20. PMID 9705992 DOI: 10.1111/j.1469-7793.1998.401bk.x  1
1998 Ripellino JA, Neve RL, Howe JR. Expression and heteromeric interactions of non-N-methyl-D-aspartate glutamate receptor subunits in the developing and adult cerebellum. Neuroscience. 82: 485-97. PMID 9466455 DOI: 10.1016/S0306-4522(97)00296-0  1
1997 Belcher SM, Howe JR. Characterization of RNA editing of the glutamate-receptor subunits GluR5 and GluR6 in granule cells during cerebellar development. Brain Research. Molecular Brain Research. 52: 130-8. PMID 9450685 DOI: 10.1016/S0169-328X(97)00252-0  1
1997 Neve RL, Howe JR, Hong S, Kalb RG. Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus. Neuroscience. 79: 435-47. PMID 9200727 DOI: 10.1016/S0306-4522(96)00645-8  1
1996 Moss GW, Marshall J, Morabito M, Howe JR, Moczydlowski E. An evolutionarily conserved binding site for serine proteinase inhibitors in large conductance calcium-activated potassium channels. Biochemistry. 35: 16024-35. PMID 8973172 DOI: 10.1021/bi961452k  1
1996 Howe JR. Homomeric and heteromeric ion channels formed from the kainate-type subunits GluR6 and KA2 have very small, but different, unitary conductances. Journal of Neurophysiology. 76: 510-9. PMID 8836240  1
1996 Beckers MC, Ernst E, Belcher S, Howe J, Levenson R, Gros P. A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2. Genomics. 36: 202-5. PMID 8812438 DOI: 10.1006/geno.1996.0447  1
1996 Carver JM, Mansson PE, Cortes-Burgos L, Shu J, Zhou LM, Howe JR, Giordano T. Cytotoxic effects of kainate ligands on HEK cell lines expressing recombinant kainate receptors. Brain Research. 720: 69-74. PMID 8782898 DOI: 10.1016/0006-8993(96)00115-1  1
1996 Belcher SM, Howe JR. Cloning of the cDNA encoding the sodium channel beta 1 subunit from rabbit. Gene. 170: 285-6. PMID 8666261 DOI: 10.1016/0378-1119(95)00871-3  1
1995 Howe JR, Skryabin BV, Belcher SM, Zerillo CA, Schmauss C. The responsiveness of a tetracycline-sensitive expression system differs in different cell lines. The Journal of Biological Chemistry. 270: 14168-74. PMID 7775477 DOI: 10.1074/jbc.270.23.14168  1
1995 Marshall J, Molloy R, Moss GW, Howe JR, Hughes TE. The jellyfish green fluorescent protein: a new tool for studying ion channel expression and function. Neuron. 14: 211-5. PMID 7531985 DOI: 10.1016/0896-6273(95)90279-1  1
1995 Belcher SM, Zerillo CA, Levenson R, Ritchie JM, Howe JR. Cloning of a sodium channel alpha subunit from rabbit Schwann cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 11034-8. PMID 7479931 DOI: 10.1073/pnas.92.24.11034  1
1993 Baker M, Howe JR, Ritchie JM. Two types of 4-aminopyridine-sensitive potassium current in rabbit Schwann cells. The Journal of Physiology. 464: 321-42. PMID 8229804  1
1992 Howe JR, Baker M, Ritchie JM. On the block of outward potassium current in rabbit Schwann cells by internal sodium ions. Proceedings. Biological Sciences / the Royal Society. 249: 309-16. PMID 1359561 DOI: 10.1098/rspb.1992.0120  1
1992 Howe JR, Ritchie JM. Multiple kinetic components of sodium channel inactivation in rabbit Schwann cells. The Journal of Physiology. 455: 529-66. PMID 1336556  1
1991 Howe JR, Ritchie JM. On the active form of 4-aminopyridine: block of K+ currents in rabbit Schwann cells. The Journal of Physiology. 433: 183-205. PMID 1841938  1
1991 Howe JR, Cull-Candy SG, Colquhoun D. Currents through single glutamate receptor channels in outside-out patches from rat cerebellar granule cells. The Journal of Physiology. 432: 143-202. PMID 1715916  1
1990 Howe JR, Ritchie JM. Sodium currents in Schwann cells from myelinated and non-myelinated nerves of neonatal and adult rabbits. The Journal of Physiology. 425: 169-210. PMID 2170628  1
1989 Cull-Candy SG, Howe JR, Usowicz MM. Single glutamate-receptor channels in mammalian cerebellar neurones Fernstrom Foundation Series. 13: 311-328.  1
1988 Howe JR, Ritchie JM. Two types of potassium current in rabbit cultured Schwann cells. Proceedings of the Royal Society of London. Series B, Biological Sciences. 235: 19-27. PMID 2467306 DOI: 10.1098/rspb.1988.0061  1
1988 Cull-Candy SG, Howe JR, Ogden DC. Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones. The Journal of Physiology. 400: 189-222. PMID 2458453  1
1988 Howe JR, Colquhoun D, Cull-Candy SG. On the kinetics of large-conductance glutamate-receptor ion channels in rat cerebellar granule neurons. Proceedings of the Royal Society of London. Series B, Biological Sciences. 233: 407-22. PMID 2456583 DOI: 10.1098/rspb.1988.0030  1
1987 Howe JR, Zieglgänsberger W. Responses of rat dorsal horn neurons to natural stimulation and to iontophoretically applied norepinephrine. The Journal of Comparative Neurology. 255: 1-17. PMID 3819006 DOI: 10.1002/cne.902550102  1
1987 Howe JR, Sutor B, Zieglgänsberger W. Characteristics of long-duration inhibitory postsynaptic potentials in rat neocortical neurons in vitro. Cellular and Molecular Neurobiology. 7: 1-18. PMID 3594515 DOI: 10.1007/BF00734986  1
1987 Howe JR, Sutor B, Zieglgänsberger W. Baclofen reduces post-synaptic potentials of rat cortical neurones by an action other than its hyperpolarizing action. The Journal of Physiology. 384: 539-69. PMID 3309263  1
1987 Howe JR, Yaksh TL, Tyce GM. Intrathecal 6-hydroxydopamine or cervical spinal hemisection reduces norepinephrine content, but not the density of alpha 2-adrenoceptors, in the cat lumbar spinal enlargement. Neuroscience. 21: 377-84. PMID 3039400 DOI: 10.1016/0306-4522(87)90128-X  1
1987 Howe JR, Yaksh TL, Go VL. The effect of unilateral dorsal root ganglionectomies or ventral rhizotomies on alpha 2-adrenoceptor binding to, and the substance P, enkephalin, and neurotensin content of, the cat lumbar spinal cord. Neuroscience. 21: 385-94. PMID 2441314 DOI: 10.1016/0306-4522(87)90129-1  1
1986 Howe JR, Zieglgänsberger W. D-baclofen does not antagonize the actions of L-baclofen on rat neocortical neurons in vitro. Neuroscience Letters. 72: 99-104. PMID 3027624 DOI: 10.1016/0304-3940(86)90626-9  1
1986 Howe JR, Yaksh TL. Characterization of [3H]rauwolscine binding to alpha 2-adrenoceptor sites in the lumbar spinal cord of the cat: comparison to such binding sites in the cat frontal cerebral cortex. Brain Research. 368: 87-100. PMID 2869820 DOI: 10.1016/0006-8993(86)91045-0  1
1984 Howe JR, Yaksh TL. [3H]p-Aminoclonidine binding to multiple alpha 2-adrenoceptor sites in homogenates of cat frontal cortex and cat spinal cord. European Journal of Pharmacology. 106: 547-59. PMID 6097461 DOI: 10.1016/0014-2999(84)90058-X  1
1984 Howe JR, Zieglgänsberger W. Spinal peptidergic and catecholaminergic systems and nociception. Neurosurgery. 15: 904-12. PMID 6083505  1
1983 Howe JR, Wang JY, Yaksh TL. Selective antagonism of the antinociceptive effect of intrathecally applied alpha adrenergic agonists by intrathecal prazosin and intrathecal yohimbine. The Journal of Pharmacology and Experimental Therapeutics. 224: 552-8. PMID 6131120  1
1982 Yaksh TL, Howe JR. Opiate receptors and their definition by antagonists. Anesthesiology. 56: 246-9. PMID 6278990  1
1982 Howe JR, Yaksh TL. Changes in sensitivity to intrathecal norepinephrine and serotonin after 6-hydroxydopamine (6-OHDA), 5,6-dihydroxytryptamine (5,6-DHT) or repeated monoamine administration. The Journal of Pharmacology and Experimental Therapeutics. 220: 311-21. PMID 6120226  1
1982 Howe JR, Wang JY, Yaksh TL. Antagonism of intrathecal α-adrenergic agonists by intrathecal prazosin and yohimbine Federation Proceedings. 41: No. 7395.  1
1980 Howe JR, Yaksh TL. Supersensitivity to the effects of intrathecally injected norepinephrine and serotonin following the intrathecal treatment of 6-hydroxydopamine or 5,6-dihydroxytryptamine in the rat Pharmacologist. 22: 331.  1
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