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Rajesh Viswanathan - Publications

Affiliations: 
2008-2018 Case Western Reserve University, Cleveland Heights, OH, United States 
 2018- IISER Tirupati 
Area:
Chemical biology, natural products chemistry
Website:
https://rvresearch.weebly.com/
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Deletti G, Green SD, Weber C, Patterson KN, Joshi SS, Khopade TM, Coban M, Veek-Wilson J, Caulfield TR, Viswanathan R, Lane AL. Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase. Nature Communications. 14: 2558. PMID 37137876 DOI: 10.1038/s41467-023-38168-3  0.801
2022 Khopade TM, Ajayan K, Vincent DM, Lane AL, Viswanathan R. Biomimetic Total Synthesis of (+)-Nocardioazine B and Analogs. The Journal of Organic Chemistry. PMID 35960860 DOI: 10.1021/acs.joc.2c01120  0.732
2021 Khopade TM, Ajayan K, Joshi SS, Lane AL, Viswanathan R. Bioinspired Brønsted Acid-Promoted Regioselective Tryptophan Isoprenylations. Acs Omega. 6: 10840-10858. PMID 34056238 DOI: 10.1021/acsomega.1c00515  0.79
2021 Bunn BM, Xu M, Webb CM, Viswanathan R. Biocatalysts from cyanobacterial hapalindole pathway afford antivirulent isonitriles against MRSA. Journal of Biosciences. 46. PMID 33952728  0.778
2017 Huff SE, Mohammed FA, Yang M, Agrawal P, Pink J, Harris ME, Dealwis CG, Viswanathan R. Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase. Journal of Medicinal Chemistry. PMID 29253340 DOI: 10.1021/Acs.Jmedchem.7B00530  0.772
2017 Knappenberger AJ, Grandhi S, Sheth R, Ahmad MF, Viswanathan R, Harris ME. Phylogenetic sequence analysis and functional studies reveal compensatory amino acid substitutions in loop 2 of human ribonucleotide reductase. The Journal of Biological Chemistry. PMID 28808063 DOI: 10.1074/Jbc.M117.798769  0.392
2017 Ahmad MF, Alam I, Huff SE, Pink J, Flanagan SA, Shewach D, Misko TA, Oleinick NL, Harte WE, Viswanathan R, Harris ME, Dealwis CG. Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716944 DOI: 10.1073/Pnas.1620220114  0.773
2016 Knappenberger AJ, Mohammed FA, Viswanathan R, Dealwis CG, Harris ME. Nucleoside analog triphosphates allosterically regulate human ribonucleotide reductase and identify chemical determinants that drive substrate specificity. Biochemistry. PMID 27634056 DOI: 10.1021/Acs.Biochem.6B00594  0.356
2015 James ED, Knuckley B, Alqahtani N, Porwal S, Ban J, Karty JA, Viswanathan R, Lane AL. Two distinct cyclodipeptide synthases from a marine actinomycete catalyze biosynthesis of the same diketopiperazine natural product. Acs Synthetic Biology. PMID 26641496 DOI: 10.1021/Acssynbio.5B00120  0.79
2015 Ahmad MF, Huff SE, Pink J, Alam I, Zhang A, Perry K, Harris ME, Misko T, Porwal SK, Oleinick NL, Miyagi M, Viswanathan R, Dealwis CG. Identification of non-nucleoside human ribonucleotide reductase modulators. Journal of Medicinal Chemistry. PMID 26488902 DOI: 10.1021/Acs.Jmedchem.5B00929  0.764
2015 Micallef ML, D'Agostino PM, Sharma D, Viswanathan R, Moffitt MC. Genome mining for natural product biosynthetic gene clusters in the Subsection V cyanobacteria. Bmc Genomics. 16: 669. PMID 26335778 DOI: 10.1186/S12864-015-1855-Z  0.6
2015 Alqahtani N, Porwal SK, James ED, Bis DM, Karty JA, Lane AL, Viswanathan R. Correction: Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis. Organic & Biomolecular Chemistry. 13: 9323. PMID 26289493 DOI: 10.1039/c5ob90142a  0.76
2015 Alqahtani N, Porwal SK, James ED, Bis DM, Karty JA, Lane AL, Viswanathan R. Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis. Organic & Biomolecular Chemistry. 13: 7177-92. PMID 26022437 DOI: 10.1039/C5Ob00537J  0.791
2015 Bis DM, Ban YH, James ED, Alqahtani N, Viswanathan R, Lane AL. Characterization of the nocardiopsin biosynthetic gene cluster reveals similarities to and differences from the rapamycin and FK-506 pathways. Chembiochem : a European Journal of Chemical Biology. 16: 990-7. PMID 25755076 DOI: 10.1002/Cbic.201500007  0.764
2015 Porwal SK, Furia E, Harris ME, Viswanathan R, Devireddy L. Synthetic, potentiometric and spectroscopic studies of chelation between Fe(III) and 2,5-DHBA supports salicylate-mode of siderophore binding interactions. Journal of Inorganic Biochemistry. 145: 1-10. PMID 25589161 DOI: 10.1016/J.Jinorgbio.2014.12.010  0.761
2015 Alqahtani N, Porwal SK, James ED, Bis DM, Karty JA, Lane AL, Viswanathan R. Correction: Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis Organic and Biomolecular Chemistry. 13: 9323. DOI: 10.1039/c5ob90142a  0.732
2014 Thandavamurthy K, Sharma D, Porwal SK, Ray D, Viswanathan R. Regioselective cope rearrangement and prenyl transfers on indole scaffold mimicking fungal and bacterial dimethylallyltryptophan synthases. The Journal of Organic Chemistry. 79: 10049-67. PMID 25244629 DOI: 10.1021/Jo501651Z  0.791
2014 Micallef ML, Sharma D, Bunn BM, Gerwick L, Viswanathan R, Moffitt MC. Comparative analysis of hapalindole, ambiguine and welwitindolinone gene clusters and reconstitution of indole-isonitrile biosynthesis from cyanobacteria. Bmc Microbiology. 14: 213. PMID 25198896 DOI: 10.1186/S12866-014-0213-7  0.765
2014 Liu Z, Reba S, Chen WD, Porwal SK, Boom WH, Petersen RB, Rojas R, Viswanathan R, Devireddy L. Regulation of mammalian siderophore 2,5-DHBA in the innate immune response to infection. The Journal of Experimental Medicine. 211: 1197-213. PMID 24863067 DOI: 10.1084/Jem.20132629  0.759
2014 Yu G, Kuo D, Shoham M, Viswanathan R. Combinatorial synthesis and in vitro evaluation of a biaryl hydroxyketone library as antivirulence agents against MRSA. Acs Combinatorial Science. 16: 85-91. PMID 24372007 DOI: 10.1021/Co400142T  0.37
2014 James E, Alqahtani N, Viswanathan R, Lane A. Cyclodipeptide synthase-derived diketopiperazine natural products from a Nocardiopsis sp. Planta Medica. 80. DOI: 10.1055/s-0034-1382631  0.729
2014 Lane A, James E, Bis D, Alqahtani N, Viswanathan R. Molecular basis for natural product biosynthesis by Nocardiopsis sp. CMB-M0232 Planta Medica. 80. DOI: 10.1055/s-0034-1382360  0.716
2013 Voelker AE, Viswanathan R. Synthesis of a suite of bioorthogonal glutathione S-transferase substrates and their enzymatic incorporation for protein immobilization. The Journal of Organic Chemistry. 78: 9647-58. PMID 23984983 DOI: 10.1021/Jo401278X  0.774
2013 Voelker AE, Viswanathan R. Self-catalyzed immobilization of GST-fusion proteins for genome-encoded biochips. Bioconjugate Chemistry. 24: 1295-301. PMID 23883098 DOI: 10.1021/Bc400128G  0.761
2013 Viswanathan R, Labadie GR, Poulter CD. Regioselective covalent immobilization of catalytically active glutathione S-transferase on glass slides. Bioconjugate Chemistry. 24: 571-7. PMID 23458569 DOI: 10.1021/Bc300462J  0.719
2011 Ignatenko VA, Zhang P, Viswanathan R. Step-economic synthesis of (±)-debromoflustramine A using indole C3 activation strategy Tetrahedron Letters. 52: 1269-1272. DOI: 10.1016/J.Tetlet.2011.01.020  0.383
2010 Ignatenko VA, Deligonul N, Viswanathan R. Branch-selective synthesis of oxindole and indene scaffolds: transition metal-controlled intramolecular aryl amidation leading to c3 reverse-prenylated oxindoles. Organic Letters. 12: 3594-7. PMID 20704399 DOI: 10.1021/Ol1012372  0.373
2008 Viswanathan R, Smith CR, Prabhakaran EN, Johnston JN. Free radical-mediated aryl amination: convergent two- and three-component couplings to chiral 2,3-disubstituted indolines. The Journal of Organic Chemistry. 73: 3040-6. PMID 18351776 DOI: 10.1021/Jo702523U  0.765
2008 Chandra A, Viswanathan R, Johnston JN. ChemInform Abstract: Synthesis of the ABC- (I) and D-Ring Systems (II) of the Indole Alkaloid Ambiguine G (III). Cheminform. 39. DOI: 10.1002/chin.200817202  0.503
2007 Labadie GR, Viswanathan R, Poulter CD. Farnesyl diphosphate analogues with omega-bioorthogonal azide and alkyne functional groups for protein farnesyl transferase-catalyzed ligation reactions. The Journal of Organic Chemistry. 72: 9291-7. PMID 17979291 DOI: 10.1021/Jo7017747  0.735
2007 Chandra A, Viswanathan R, Johnston JN. Synthesis of the ABC- and D-ring systems of the indole alkaloid ambiguine G. Organic Letters. 9: 5027-9. PMID 17975918 DOI: 10.1021/Ol702247A  0.574
2005 Srinivasan JM, Burks HE, Smith CR, Viswanathan R, Johnston JN. Free radical-mediated aryl amination: A practical synthesis of (R)- and (S)-7-azaindoline α-amino acid Synthesis. 330-333. DOI: 10.1055/S-2004-831226  0.791
2004 Srinivasan JM, Burks HE, Smith CR, Viswanathan R, Johnston JN. Free Radical-Mediated Aryl Amination: A Practical Synthesis of ()- and ()-7-Azaindoline α-Amino Acid. Synthesis. 2005: 330-333. PMID 36277480 DOI: 10.1055/s-2004-831226  0.794
2004 Mullins RJ, Vedernikov A, Viswanathan R. Competition experiments as a means of evaluating linear free energy relationships. An experiment for the advanced undergraduate organic chemistry lab Journal of Chemical Education. 81: 1357-1361. DOI: 10.1021/Ed081P1357  0.32
2003 Viswanathan R, Mutnick D, Johnston JN. The first azacyclopentenyl carbinyl radical isomerizations (ACCRI): independent use of steric and electronic (polarization) effects as gating elements. Journal of the American Chemical Society. 125: 7266-71. PMID 12797800 DOI: 10.1021/Ja029426Z  0.595
2003 Viswanathan R, Prabhakaran EN, Plotkin MA, Johnston JN. Free radical-mediated aryl amination and its use in a convergent [3 + 2] strategy for enantioselective indoline alpha-amino acid synthesis. Journal of the American Chemical Society. 125: 163-8. PMID 12515518 DOI: 10.1021/Ja0284308  0.758
2001 Johnston JN, Plotkin MA, Viswanathan R, Prabhakaran EN. Nonconventional carbon additions to azomethines. aryl amination/indoline synthesis by direct aryl radical addition to azomethine nitrogen. Organic Letters. 3: 1009-11. PMID 11277782 DOI: 10.1021/Ol007065R  0.752
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