| Year |
Citation |
Score |
| 2023 |
Deretic V. Atg8ylation as a host-protective mechanism against . Frontiers in Tuberculosis. 1. PMID 37901138 DOI: 10.3389/ftubr.2023.1275882 |
0.319 |
|
| 2020 |
Kumar S, Jain A, Choi SW, da Silva GPD, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V. Author Correction: Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens. Nature Cell Biology. PMID 32788721 DOI: 10.1038/S41556-020-0574-0 |
0.302 |
|
| 2020 |
Kumar S, Jain A, Choi SW, da Silva GPD, Allers L, Mudd MH, Peters RS, Anonsen JH, Rusten TE, Lazarou M, Deretic V. Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens. Nature Cell Biology. 22: 973-985. PMID 32753672 DOI: 10.1038/S41556-020-0549-1 |
0.419 |
|
| 2020 |
Jia J, Bissa B, Brecht L, Allers L, Choi SW, Gu Y, Zbinden M, Burge MR, Timmins G, Hallows K, Behrends C, Deretic V. AMPK is activated during lysosomal damage via a galectin-ubiquitin signal transduction system. Autophagy. PMID 32597364 DOI: 10.1080/15548627.2020.1788890 |
0.351 |
|
| 2020 |
Jia J, Claude-Taupin A, Gu Y, Choi SW, Peters R, Bissa B, Mudd MH, Allers L, Pallikkuth S, Lidke KA, Salemi M, Phinney B, Mari M, Reggiori F, Deretic V. MERIT, a cellular system coordinating lysosomal repair, removal and replacement. Autophagy. PMID 32521192 DOI: 10.1080/15548627.2020.1779451 |
0.325 |
|
| 2020 |
Binder JL, Chander P, Deretic V, Weick JP, Bhaskar K. Optical induction of autophagy via Transcription factor EB (TFEB) reduces pathological tau in neurons. Plos One. 15: e0230026. PMID 32208437 DOI: 10.1371/Journal.Pone.0230026 |
0.301 |
|
| 2020 |
Jia J, Bissa B, Brecht L, Allers L, Choi SW, Gu Y, Zbinden M, Burge MR, Timmins G, Hallows K, Behrends C, Deretic V. AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System. Molecular Cell. PMID 31995728 DOI: 10.1016/J.Molcel.2019.12.028 |
0.343 |
|
| 2019 |
Zhang X, Wu D, Wang C, Luo Y, Ding X, Yang X, Silva F, Arenas S, Weaver JM, Mandell M, Deretic V, Liu M. Sustained Activation of Autophagy Suppresses Adipocyte Maturation via a Lipolysis-dependent Mechanism. Autophagy. PMID 31840569 DOI: 10.1080/15548627.2019.1703355 |
0.322 |
|
| 2019 |
Jia J, Claude-Taupin A, Gu Y, Choi SW, Peters R, Bissa B, Mudd MH, Allers L, Pallikkuth S, Lidke KA, Salemi M, Phinney B, Mari M, Reggiori F, Deretic V. Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal. Developmental Cell. PMID 31813797 DOI: 10.1016/J.Devcel.2019.10.025 |
0.317 |
|
| 2019 |
Stange Overå K, Garcia Garcia J, Bhujabal Z, Jain A, Øvervatn A, Larsen KB, Deretic V, Johansen T, Lamark T, Sjøttem E. TRIM32 acts both as a substrate and a positive regulator of p62/SQSTM1 impaired in a muscular dystrophy disease. Journal of Cell Science. PMID 31685529 DOI: 10.1242/Jcs.236596 |
0.37 |
|
| 2019 |
Gu Y, Princely Abudu Y, Kumar S, Bissa B, Choi SW, Jia J, Lazarou M, Eskelinen EL, Johansen T, Deretic V. Mammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs. The Embo Journal. e101994. PMID 31625181 DOI: 10.15252/Embj.2019101994 |
0.358 |
|
| 2019 |
Kumar S, Gu Y, Abudu YP, Bruun JA, Jain A, Farzam F, Mudd M, Anonsen JH, Rusten TE, Kasof G, Ktistakis N, Lidke KA, Johansen T, Deretic V. Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation. Developmental Cell. PMID 30827897 DOI: 10.1016/J.Devcel.2019.01.027 |
0.327 |
|
| 2019 |
Deretic V, Timmins GS. Enhancement of lung levels of antibiotics by ambroxol and bromhexine. Expert Opinion On Drug Metabolism & Toxicology. 15: 213-218. PMID 30721101 DOI: 10.1080/17425255.2019.1578748 |
0.311 |
|
| 2018 |
Jia J, Abudu YP, Claude-Taupin A, Gu Y, Kumar S, Choi SW, Peters R, Mudd MH, Allers L, Salemi M, Phinney B, Johansen T, Deretic V. Galectins Control MTOR and AMPK in Response to Lysosomal Damage to Induce Autophagy. Autophagy. PMID 30081722 DOI: 10.1080/15548627.2018.1505155 |
0.33 |
|
| 2018 |
Choi SW, Gu Y, Peters RS, Salgame P, Ellner JJ, Timmins GS, Deretic V. Ambroxol induces autophagy and potentiates Rifampin antimycobacterial activity. Antimicrobial Agents and Chemotherapy. PMID 30012752 DOI: 10.1128/Aac.01019-18 |
0.343 |
|
| 2018 |
Jia J, Abudu YP, Claude-Taupin A, Gu Y, Kumar S, Choi SW, Peters R, Mudd MH, Allers L, Salemi M, Phinney B, Johansen T, Deretic V. Galectins Control mTOR in Response to Endomembrane Damage. Molecular Cell. 70: 120-135.e8. PMID 29625033 DOI: 10.1016/J.Molcel.2018.03.009 |
0.341 |
|
| 2018 |
Claude-Taupin A, Bissa B, Jia J, Gu Y, Deretic V. Role of autophagy in IL-1β export and release from cells. Seminars in Cell & Developmental Biology. PMID 29580970 DOI: 10.1016/J.Semcdb.2018.03.012 |
0.31 |
|
| 2018 |
Kumar S, Jain A, Farzam F, Jia J, Gu Y, Choi SW, Mudd MH, Claude-Taupin A, Wester MJ, Lidke KA, Rusten TE, Deretic V. Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins. The Journal of Cell Biology. PMID 29420192 DOI: 10.1083/Jcb.201708039 |
0.344 |
|
| 2018 |
Deretic V, Klionsky DJ. Autophagy and inflammation: a special review issue. Autophagy. 1-4. PMID 29304718 DOI: 10.1080/15548627.2017.1412229 |
0.314 |
|
| 2017 |
Claude-Taupin A, Jia J, Mudd M, Deretic V. Autophagy's secret life: secretion instead of degradation. Essays in Biochemistry. 61: 637-647. PMID 29233874 DOI: 10.1042/Ebc20170024 |
0.31 |
|
| 2017 |
Deretic V, Levine B. Autophagy balances inflammation in innate immunity. Autophagy. 1-29. PMID 29165043 DOI: 10.1080/15548627.2017.1402992 |
0.335 |
|
| 2017 |
Kimura T, Jia J, Claude-Taupin A, Kumar S, Choi SW, Gu Y, Mudd M, Dupont N, Jiang S, Peters R, Farzam F, Jain A, Lidke KA, Adams CM, Johansen T, ... Deretic V, et al. Cellular and molecular mechanism for secretory autophagy. Autophagy. 0. PMID 28368721 DOI: 10.1080/15548627.2017.1307486 |
0.331 |
|
| 2016 |
Kimura T, Jia J, Kumar S, Choi SW, Gu Y, Mudd M, Dupont N, Jiang S, Peters R, Farzam F, Jain A, Lidke KA, Adams CM, Johansen T, Deretic V. Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagy. The Embo Journal. PMID 27932448 DOI: 10.15252/Embj.201695081 |
0.334 |
|
| 2016 |
Chauhan S, Kumar S, Jain A, Ponpuak M, Mudd MH, Kimura T, Choi SW, Peters R, Mandell M, Bruun JA, Johansen T, Deretic V. TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis. Developmental Cell. PMID 27693506 DOI: 10.1016/J.Devcel.2016.08.003 |
0.349 |
|
| 2016 |
Mandell MA, Jain A, Kumar S, Castleman MJ, Anwar T, Eskelinen EL, Johansen T, Prekeris R, Deretic V. TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation. Journal of Cell Science. PMID 27562068 DOI: 10.1242/Jcs.190017 |
0.34 |
|
| 2016 |
Deretic V. Autophagy in leukocytes and other cells: mechanisms, subsystem organization, selectivity, and links to innate immunity. Journal of Leukocyte Biology. PMID 27493243 DOI: 10.1189/Jlb.4Mr0216-079R |
0.335 |
|
| 2016 |
Kimura T, Jain A, Choi SW, Mandell MA, Johansen T, Deretic V. TRIM-Directed Selective Autophagy Regulates Immune Activation. Autophagy. 0. PMID 26983397 DOI: 10.1080/15548627.2016.1154254 |
0.361 |
|
| 2016 |
Kimura T, Mandell M, Deretic V. Precision autophagy directed by receptor regulators - emerging examples within the TRIM family. Journal of Cell Science. 129: 881-91. PMID 26906420 DOI: 10.1242/Jcs.163758 |
0.303 |
|
| 2016 |
Gupta A, Misra A, Deretic V. Targeted pulmonary delivery of inducers of host macrophage autophagy as a potential host-directed chemotherapy of tuberculosis. Advanced Drug Delivery Reviews. PMID 26829287 DOI: 10.1016/J.Addr.2016.01.016 |
0.359 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Deretic V, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.329 |
|
| 2015 |
Chauhan S, Ahmed Z, Bradfute SB, Arko-Mensah J, Mandell MA, Won Choi S, Kimura T, Blanchet F, Waller A, Mudd MH, Jiang S, Sklar L, Timmins GS, Maphis N, Bhaskar K, ... ... Deretic V, et al. Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nature Communications. 6: 8620. PMID 26503418 DOI: 10.1038/Ncomms9620 |
0.337 |
|
| 2015 |
Kimura T, Jain A, Choi SW, Mandell MA, Schroder K, Johansen T, Deretic V. TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity. The Journal of Cell Biology. PMID 26347139 DOI: 10.1083/Jcb.201503023 |
0.352 |
|
| 2015 |
Chauhan S, Mandell MA, Deretic V. Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy. Autophagy. 0. PMID 26313894 DOI: 10.1080/15548627.2015.1084457 |
0.366 |
|
| 2015 |
Rubinsztein DC, Bento CF, Deretic V. Therapeutic targeting of autophagy in neurodegenerative and infectious diseases. The Journal of Experimental Medicine. 212: 979-90. PMID 26101267 DOI: 10.1084/Jem.20150956 |
0.336 |
|
| 2015 |
Chauhan S, Mandell MA, Deretic V. IRGM Governs the Core Autophagy Machinery to Conduct Antimicrobial Defense. Molecular Cell. 58: 507-21. PMID 25891078 DOI: 10.1016/J.Molcel.2015.03.020 |
0.348 |
|
| 2015 |
Deretic V, Kimura T, Timmins G, Moseley P, Chauhan S, Mandell M. Immunologic manifestations of autophagy. The Journal of Clinical Investigation. 125: 75-84. PMID 25654553 DOI: 10.1172/Jci73945 |
0.351 |
|
| 2014 |
Mandell MA, Kimura T, Jain A, Johansen T, Deretic V. TRIM proteins regulate autophagy: TRIM5 is a selective autophagy receptor mediating HIV-1 restriction. Autophagy. 10: 2387-8. PMID 25587751 DOI: 10.4161/15548627.2014.984278 |
0.32 |
|
| 2014 |
Deretic V. Autophagy in tuberculosis. Cold Spring Harbor Perspectives in Medicine. 4: a018481. PMID 25167980 DOI: 10.1101/Cshperspect.A018481 |
0.369 |
|
| 2014 |
Mandell MA, Jain A, Arko-Mensah J, Chauhan S, Kimura T, Dinkins C, Silvestri G, Münch J, Kirchhoff F, Simonsen A, Wei Y, Levine B, Johansen T, Deretic V. TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition. Developmental Cell. 30: 394-409. PMID 25127057 DOI: 10.1016/J.Devcel.2014.06.013 |
0.339 |
|
| 2014 |
Dupont N, Chauhan S, Arko-Mensah J, Castillo EF, Masedunskas A, Weigert R, Robenek H, Proikas-Cezanne T, Deretic V. Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis. Current Biology : Cb. 24: 609-20. PMID 24613307 DOI: 10.1016/J.Cub.2014.02.008 |
0.315 |
|
| 2013 |
Deretic V, Saitoh T, Akira S. Autophagy in infection, inflammation and immunity. Nature Reviews. Immunology. 13: 722-37. PMID 24064518 DOI: 10.1038/Nri3532 |
0.352 |
|
| 2013 |
He S, Ni D, Ma B, Lee JH, Zhang T, Ghozalli I, Pirooz SD, Zhao Z, Bharatham N, Li B, Oh S, Lee WH, Takahashi Y, Wang HG, Minassian A, ... ... Deretic V, et al. PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex. Nature Cell Biology. 15: 1206-19. PMID 24056303 DOI: 10.1038/Ncb2848 |
0.339 |
|
| 2013 |
Schroder K, Deretic V. Innate immunity, the constant gardener of antimicrobial defense. Current Opinion in Microbiology. 16: 293-5. PMID 23880137 DOI: 10.1016/J.Mib.2013.06.007 |
0.345 |
|
| 2013 |
Bradfute SB, Castillo EF, Arko-Mensah J, Chauhan S, Jiang S, Mandell M, Deretic V. Autophagy as an immune effector against tuberculosis. Current Opinion in Microbiology. 16: 355-65. PMID 23790398 DOI: 10.1016/J.Mib.2013.05.003 |
0.415 |
|
| 2013 |
Dokladny K, Zuhl MN, Mandell M, Bhattacharya D, Schneider S, Deretic V, Moseley PL. Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy. The Journal of Biological Chemistry. 288: 14959-72. PMID 23576438 DOI: 10.1074/Jbc.M113.462408 |
0.31 |
|
| 2013 |
Jiang S, Dupont N, Castillo EF, Deretic V. Secretory versus degradative autophagy: unconventional secretion of inflammatory mediators. Journal of Innate Immunity. 5: 471-9. PMID 23445716 DOI: 10.1159/000346707 |
0.311 |
|
| 2012 |
Castillo EF, Dekonenko A, Arko-Mensah J, Mandell MA, Dupont N, Jiang S, Delgado-Vargas M, Timmins GS, Bhattacharya D, Yang H, Hutt J, Lyons CR, Dobos KM, Deretic V. Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation. Proceedings of the National Academy of Sciences of the United States of America. 109: E3168-76. PMID 23093667 DOI: 10.1073/Pnas.1210500109 |
0.381 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Deretic V, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.301 |
|
| 2012 |
Pilli M, Arko-Mensah J, Ponpuak M, Roberts E, Master S, Mandell MA, Dupont N, Ornatowski W, Jiang S, Bradfute SB, Bruun JA, Hansen TE, Johansen T, Deretic V. TBK-1 promotes autophagy-mediated antimicrobial defense by controlling autophagosome maturation. Immunity. 37: 223-34. PMID 22921120 DOI: 10.1016/J.Immuni.2012.04.015 |
0.437 |
|
| 2012 |
Deretic V. Autophagy: an emerging immunological paradigm. Journal of Immunology (Baltimore, Md. : 1950). 189: 15-20. PMID 22723639 DOI: 10.4049/Jimmunol.1102108 |
0.341 |
|
| 2012 |
Deretic V, Jiang S, Dupont N. Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation. Trends in Cell Biology. 22: 397-406. PMID 22677446 DOI: 10.1016/J.Tcb.2012.04.008 |
0.367 |
|
| 2012 |
Deretic V. Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors. Current Opinion in Immunology. 24: 21-31. PMID 22118953 DOI: 10.1016/J.Coi.2011.10.006 |
0.365 |
|
| 2011 |
Dupont N, Jiang S, Pilli M, Ornatowski W, Bhattacharya D, Deretic V. Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β. The Embo Journal. 30: 4701-11. PMID 22068051 DOI: 10.1038/Emboj.2011.398 |
0.34 |
|
| 2011 |
Klionsky DJ, Baehrecke EH, Brumell JH, Chu CT, Codogno P, Cuervo AM, Debnath J, Deretic V, Elazar Z, Eskelinen EL, Finkbeiner S, Fueyo-Margareto J, Gewirtz D, Jäättelä M, Kroemer G, et al. A comprehensive glossary of autophagy-related molecules and processes (2nd edition). Autophagy. 7: 1273-94. PMID 21997368 DOI: 10.4161/Auto.7.11.17661 |
0.322 |
|
| 2011 |
Johansen P, Fettelschoss A, Amstutz B, Selchow P, Waeckerle-Men Y, Keller P, Deretic V, Held L, Kündig TM, Böttger EC, Sander P. Relief from Zmp1-mediated arrest of phagosome maturation is associated with facilitated presentation and enhanced immunogenicity of mycobacterial antigens. Clinical and Vaccine Immunology : Cvi. 18: 907-13. PMID 21471301 DOI: 10.1128/Cvi.00015-11 |
0.331 |
|
| 2011 |
Korolchuk VI, Saiki S, Lichtenberg M, Siddiqi FH, Roberts EA, Imarisio S, Jahreiss L, Sarkar S, Futter M, Menzies FM, O'Kane CJ, Deretic V, Rubinsztein DC. Lysosomal positioning coordinates cellular nutrient responses. Nature Cell Biology. 13: 453-60. PMID 21394080 DOI: 10.1038/Ncb2204 |
0.338 |
|
| 2011 |
Deretic V. Autophagy in immunity and cell-autonomous defense against intracellular microbes. Immunological Reviews. 240: 92-104. PMID 21349088 DOI: 10.1111/J.1600-065X.2010.00995.X |
0.344 |
|
| 2011 |
Ponpuak M, Deretic V. Autophagy and p62/sequestosome 1 generate neo-antimicrobial peptides (cryptides) from cytosolic proteins. Autophagy. 7: 336-7. PMID 21187720 DOI: 10.4161/Auto.7.3.14500 |
0.324 |
|
| 2010 |
Singh SB, Ornatowski W, Vergne I, Naylor J, Delgado M, Roberts E, Ponpuak M, Master S, Pilli M, White E, Komatsu M, Deretic V. Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria. Nature Cell Biology. 12: 1154-65. PMID 21102437 DOI: 10.1038/Ncb2119 |
0.326 |
|
| 2010 |
Deretic V. Autophagy of intracellular microbes and mitochondria: two sides of the same coin? F1000 Biology Reports. 2. PMID 20948788 DOI: 10.3410/B2-45 |
0.355 |
|
| 2010 |
Klionsky DJ, Codogno P, Cuervo AM, Deretic V, Elazar Z, Fueyo-Margareto J, Gewirtz DA, Kroemer G, Levine B, Mizushima N, Rubinsztein DC, Thumm M, Tooze SA. A comprehensive glossary of autophagy-related molecules and processes. Autophagy. 6: 438-48. PMID 20484971 DOI: 10.4161/Auto.6.4.12244 |
0.319 |
|
| 2010 |
Dinkins C, Arko-Mensah J, Deretic V. Autophagy and HIV. Seminars in Cell & Developmental Biology. 21: 712-8. PMID 20403451 DOI: 10.1016/J.Semcdb.2010.04.004 |
0.311 |
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| 2010 |
Ponpuak M, Davis AS, Roberts EA, Delgado MA, Dinkins C, Zhao Z, Virgin HW, Kyei GB, Johansen T, Vergne I, Deretic V. Delivery of cytosolic components by autophagic adaptor protein p62 endows autophagosomes with unique antimicrobial properties. Immunity. 32: 329-41. PMID 20206555 DOI: 10.1016/J.Immuni.2010.02.009 |
0.419 |
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| 2010 |
Vergne I, Deretic V. The role of PI3P phosphatases in the regulation of autophagy. Febs Letters. 584: 1313-8. PMID 20188094 DOI: 10.1016/J.Febslet.2010.02.054 |
0.37 |
|
| 2010 |
Deretic V. Autophagy in infection. Current Opinion in Cell Biology. 22: 252-62. PMID 20116986 DOI: 10.1016/J.Ceb.2009.12.009 |
0.415 |
|
| 2009 |
Deretic V, Delgado M, Vergne I, Master S, De Haro S, Ponpuak M, Singh S. Autophagy in immunity against mycobacterium tuberculosis: a model system to dissect immunological roles of autophagy. Current Topics in Microbiology and Immunology. 335: 169-88. PMID 19802565 DOI: 10.1007/978-3-642-00302-8_8 |
0.395 |
|
| 2009 |
Deretic V. Links between autophagy, innate immunity, inflammation and Crohn's disease. Digestive Diseases (Basel, Switzerland). 27: 246-51. PMID 19786748 DOI: 10.1159/000228557 |
0.342 |
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| 2009 |
Vergne I, Roberts E, Elmaoued RA, Tosch V, Delgado MA, Proikas-Cezanne T, Laporte J, Deretic V. Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy. The Embo Journal. 28: 2244-58. PMID 19590496 DOI: 10.1038/Emboj.2009.159 |
0.381 |
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| 2009 |
Deretic V, Levine B. Autophagy, immunity, and microbial adaptations. Cell Host & Microbe. 5: 527-49. PMID 19527881 DOI: 10.1016/J.Chom.2009.05.016 |
0.349 |
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| 2009 |
Delgado MA, Deretic V. Toll-like receptors in control of immunological autophagy. Cell Death and Differentiation. 16: 976-83. PMID 19444282 DOI: 10.1038/Cdd.2009.40 |
0.341 |
|
| 2009 |
Deretic V. Strange bedfellows expose ancient secrets of autophagy in immunity. Immunity. 30: 479-81. PMID 19371713 DOI: 10.1016/J.Immuni.2009.03.005 |
0.341 |
|
| 2009 |
Deretic V. Multiple regulatory and effector roles of autophagy in immunity. Current Opinion in Immunology. 21: 53-62. PMID 19269148 DOI: 10.1016/J.Coi.2009.02.002 |
0.357 |
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| 2009 |
Ponpuak M, Delgado MA, Elmaoued RA, Deretic V. Monitoring autophagy during Mycobacterium tuberculosis infection. Methods in Enzymology. 452: 345-61. PMID 19200892 DOI: 10.1016/S0076-6879(08)03621-5 |
0.386 |
|
| 2009 |
Delgado M, Singh S, De Haro S, Master S, Ponpuak M, Dinkins C, Ornatowski W, Vergne I, Deretic V. Autophagy and pattern recognition receptors in innate immunity. Immunological Reviews. 227: 189-202. PMID 19120485 DOI: 10.1111/J.1600-065X.2008.00725.X |
0.354 |
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| 2009 |
Harris J, Master SS, De Haro SA, Delgado M, Roberts EA, Hope JC, Keane J, Deretic V. Th1-Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages. Veterinary Immunology and Immunopathology. 128: 37-43. PMID 19026454 DOI: 10.1016/J.Vetimm.2008.10.293 |
0.352 |
|
| 2008 |
Zhao Z, Fux B, Goodwin M, Dunay IR, Strong D, Miller BC, Cadwell K, Delgado MA, Ponpuak M, Green KG, Schmidt RE, Mizushima N, Deretic V, Sibley LD, Virgin HW. Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens. Cell Host & Microbe. 4: 458-69. PMID 18996346 DOI: 10.1016/J.Chom.2008.10.003 |
0.41 |
|
| 2008 |
Deretic V. Autophagy, an immunologic magic bullet: Mycobacterium tuberculosis phagosome maturation block and how to bypass it. Future Microbiology. 3: 517-24. PMID 18811236 DOI: 10.2217/17460913.3.5.517 |
0.404 |
|
| 2008 |
Liang C, Lee JS, Inn KS, Gack MU, Li Q, Roberts EA, Vergne I, Deretic V, Feng P, Akazawa C, Jung JU. Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking. Nature Cell Biology. 10: 776-87. PMID 18552835 DOI: 10.1038/Ncb1740 |
0.326 |
|
| 2008 |
Deretic V, Klionsky DJ. How cells clean house. Scientific American. 298: 74-81. PMID 18444328 DOI: 10.1038/Scientificamerican0508-74 |
0.305 |
|
| 2008 |
Roberts EA, Deretic V. The Mycobacterium tuberculosis phagosome. Methods in Molecular Biology (Clifton, N.J.). 445: 439-49. PMID 18425467 DOI: 10.1007/978-1-59745-157-4_28 |
0.398 |
|
| 2008 |
Vergne I, Deretic V. In vitro phagosome-endosome fusion. Methods in Molecular Biology (Clifton, N.J.). 445: 301-9. PMID 18425458 DOI: 10.1007/978-1-59745-157-4_19 |
0.326 |
|
| 2008 |
Roberts EA, Deretic V. Autophagic proteolysis of long-lived proteins in nonliver cells. Methods in Molecular Biology (Clifton, N.J.). 445: 111-7. PMID 18425445 DOI: 10.1007/978-1-59745-157-4_6 |
0.306 |
|
| 2008 |
Deretic V. Autophagosome and phagosome. Methods in Molecular Biology (Clifton, N.J.). 445: 1-10. PMID 18425440 DOI: 10.1007/978-1-59745-157-4_1 |
0.352 |
|
| 2008 |
Master SS, Rampini SK, Davis AS, Keller C, Ehlers S, Springer B, Timmins GS, Sander P, Deretic V. Mycobacterium tuberculosis prevents inflammasome activation. Cell Host & Microbe. 3: 224-32. PMID 18407066 DOI: 10.1016/J.Chom.2008.03.003 |
0.318 |
|
| 2008 |
Delgado MA, Elmaoued RA, Davis AS, Kyei G, Deretic V. Toll-like receptors control autophagy. The Embo Journal. 27: 1110-21. PMID 18337753 DOI: 10.1038/Emboj.2008.31 |
0.344 |
|
| 2007 |
Davis AS, Vergne I, Master SS, Kyei GB, Chua J, Deretic V. Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes. Plos Pathogens. 3: e186. PMID 18069890 DOI: 10.1371/Journal.Ppat.0030186 |
0.604 |
|
| 2007 |
Ornatowski W, Poschet JF, Perkett E, Taylor-Cousar JL, Deretic V. Elevated furin levels in human cystic fibrosis cells result in hypersusceptibility to exotoxin A-induced cytotoxicity. The Journal of Clinical Investigation. 117: 3489-97. PMID 17948127 DOI: 10.1172/Jci31499 |
0.416 |
|
| 2007 |
Harris J, De Haro SA, Master SS, Keane J, Roberts EA, Delgado M, Deretic V. T helper 2 cytokines inhibit autophagic control of intracellular Mycobacterium tuberculosis. Immunity. 27: 505-17. PMID 17892853 DOI: 10.1016/J.Immuni.2007.07.022 |
0.357 |
|
| 2007 |
Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nature Reviews. Immunology. 7: 767-77. PMID 17767194 DOI: 10.1038/Nri2161 |
0.368 |
|
| 2007 |
Poschet JF, Timmins GS, Taylor-Cousar JL, Ornatowski W, Fazio J, Perkett E, Wilson KR, Yu HD, de Jonge HR, Deretic V. Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L712-9. PMID 17586695 DOI: 10.1152/Ajplung.00314.2006 |
0.386 |
|
| 2007 |
Wood SR, Firoved AM, Ornatowski W, Mai T, Deretic V, Timmins GS. Nitrosative stress inhibits production of the virulence factor alginate in mucoid Pseudomonas aeruginosa. Free Radical Research. 41: 208-15. PMID 17364947 DOI: 10.1080/10715760601052610 |
0.809 |
|
| 2007 |
Deretic V, Singh S, Master S, Kyei G, Davis A, Naylor J, de Haro S, Harris J, Delgado M, Roberts E, Vergne I. Phosphoinositides in phagolysosome and autophagosome biogenesis. Biochemical Society Symposium. 141-8. PMID 17233587 DOI: 10.1042/Bss0740141 |
0.438 |
|
| 2007 |
Harris J, De Haro SA, Master SS, Keane J, Roberts EA, Delgado M, Deretic V. T Helper 2 Cytokines Inhibit Autophagic Control of Intracellular Mycobacterium tuberculosis (DOI:10.1016/j.immuni.2007.07.022) Immunity. 27: 685. DOI: 10.1016/J.Immuni.2007.09.003 |
0.304 |
|
| 2006 |
Kyei GB, Vergne I, Chua J, Roberts E, Harris J, Junutula JR, Deretic V. Rab14 is critical for maintenance of Mycobacterium tuberculosis phagosome maturation arrest. The Embo Journal. 25: 5250-9. PMID 17082769 DOI: 10.1038/Sj.Emboj.7601407 |
0.645 |
|
| 2006 |
Roberts EA, Chua J, Kyei GB, Deretic V. Higher order Rab programming in phagolysosome biogenesis. The Journal of Cell Biology. 174: 923-9. PMID 16982798 DOI: 10.1083/Jcb.200603026 |
0.633 |
|
| 2006 |
Singh SB, Davis AS, Taylor GA, Deretic V. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science (New York, N.Y.). 313: 1438-41. PMID 16888103 DOI: 10.1126/Science.1129577 |
0.408 |
|
| 2006 |
Vergne I, Singh S, Roberts E, Kyei G, Master S, Harris J, de Haro S, Naylor J, Davis A, Delgado M, Deretic V. Autophagy in immune defense against Mycobacterium tuberculosis. Autophagy. 2: 175-8. PMID 16874111 DOI: 10.4161/Auto.2830 |
0.393 |
|
| 2006 |
Deretic V. Autophagy as an immune defense mechanism. Current Opinion in Immunology. 18: 375-82. PMID 16782319 DOI: 10.1016/J.Coi.2006.05.019 |
0.374 |
|
| 2006 |
Delgado MA, Poschet JF, Deretic V. Nonclassical pathway of Pseudomonas aeruginosa DNA-induced interleukin-8 secretion in cystic fibrosis airway epithelial cells. Infection and Immunity. 74: 2975-84. PMID 16622236 DOI: 10.1128/Iai.74.5.2975-2984.2006 |
0.397 |
|
| 2006 |
Poschet JF, Fazio JA, Timmins GS, Ornatowski W, Perkett E, Delgado M, Deretic V. Endosomal hyperacidification in cystic fibrosis is due to defective nitric oxide-cylic GMP signalling cascade. Embo Reports. 7: 553-9. PMID 16612392 DOI: 10.1038/Sj.Embor.7400674 |
0.37 |
|
| 2006 |
Deretic V, Singh S, Master S, Harris J, Roberts E, Kyei G, Davis A, de Haro S, Naylor J, Lee HH, Vergne I. Mycobacterium tuberculosis inhibition of phagolysosome biogenesis and autophagy as a host defence mechanism. Cellular Microbiology. 8: 719-27. PMID 16611222 DOI: 10.1111/J.1462-5822.2006.00705.X |
0.445 |
|
| 2006 |
Pagán-Ramos E, Master SS, Pritchett CL, Reimschuessel R, Trucksis M, Timmins GS, Deretic V. Molecular and physiological effects of mycobacterial oxyR inactivation. Journal of Bacteriology. 188: 2674-80. PMID 16547055 DOI: 10.1128/Jb.188.7.2674-2680.2006 |
0.412 |
|
| 2006 |
Roberts EA, Vergne I, Deretic V. The inhibition of phagolysosomal biogenesis is fundamental to tuberculosis Drug Discovery Today: Disease Mechanisms. 3: 247-252. DOI: 10.1016/J.Ddmec.2006.06.010 |
0.353 |
|
| 2005 |
Deretic V. Autophagy in innate and adaptive immunity. Trends in Immunology. 26: 523-8. PMID 16099218 DOI: 10.1016/J.It.2005.08.003 |
0.337 |
|
| 2005 |
Vergne I, Chua J, Lee HH, Lucas M, Belisle J, Deretic V. Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 4033-8. PMID 15753315 DOI: 10.1073/Pnas.0409716102 |
0.619 |
|
| 2004 |
Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, Deretic V. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell. 119: 753-66. PMID 15607973 DOI: 10.1016/J.Cell.2004.11.038 |
0.418 |
|
| 2004 |
Vergne I, Chua J, Singh SB, Deretic V. Cell biology of mycobacterium tuberculosis phagosome. Annual Review of Cell and Developmental Biology. 20: 367-94. PMID 15473845 DOI: 10.1146/Annurev.Cellbio.20.010403.114015 |
0.636 |
|
| 2004 |
Deretic V, Vergne I, Chua J, Master S, Singh SB, Fazio JA, Kyei G. Endosomal membrane traffic: convergence point targeted by Mycobacterium tuberculosis and HIV. Cellular Microbiology. 6: 999-1009. PMID 15469429 DOI: 10.1111/J.1462-5822.2004.00449.X |
0.623 |
|
| 2004 |
Firoved AM, Ornatowski W, Deretic V. Microarray analysis reveals induction of lipoprotein genes in mucoid Pseudomonas aeruginosa: implications for inflammation in cystic fibrosis. Infection and Immunity. 72: 5012-8. PMID 15321993 DOI: 10.1128/Iai.72.9.5012-5018.2004 |
0.811 |
|
| 2004 |
Chua J, Deretic V. Mycobacterium tuberculosis reprograms waves of phosphatidylinositol 3-phosphate on phagosomal organelles. The Journal of Biological Chemistry. 279: 36982-92. PMID 15210698 DOI: 10.1074/Jbc.M405082200 |
0.587 |
|
| 2004 |
Firoved AM, Wood SR, Ornatowski W, Deretic V, Timmins GS. Microarray analysis and functional characterization of the nitrosative stress response in nonmucoid and mucoid Pseudomonas aeruginosa. Journal of Bacteriology. 186: 4046-50. PMID 15175322 DOI: 10.1128/Jb.186.12.4046-4050.2004 |
0.776 |
|
| 2004 |
Miller BH, Fratti RA, Poschet JF, Timmins GS, Master SS, Burgos M, Marletta MA, Deretic V. Mycobacteria inhibit nitric oxide synthase recruitment to phagosomes during macrophage infection. Infection and Immunity. 72: 2872-8. PMID 15102799 DOI: 10.1128/Iai.72.5.2872-2878.2004 |
0.674 |
|
| 2004 |
Chua J, Vergne I, Master S, Deretic V. A tale of two lipids: Mycobacterium tuberculosis phagosome maturation arrest. Current Opinion in Microbiology. 7: 71-7. PMID 15036144 DOI: 10.1016/J.Mib.2003.12.011 |
0.624 |
|
| 2004 |
Vergne I, Fratti RA, Hill PJ, Chua J, Belisle J, Deretic V. Mycobacterium tuberculosis phagosome maturation arrest: mycobacterial phosphatidylinositol analog phosphatidylinositol mannoside stimulates early endosomal fusion. Molecular Biology of the Cell. 15: 751-60. PMID 14617817 DOI: 10.1091/Mbc.E03-05-0307 |
0.754 |
|
| 2003 |
Fratti RA, Chua J, Deretic V. Induction of p38 mitogen-activated protein kinase reduces early endosome autoantigen 1 (EEA1) recruitment to phagosomal membranes. The Journal of Biological Chemistry. 278: 46961-7. PMID 12963735 DOI: 10.1074/Jbc.M305225200 |
0.775 |
|
| 2003 |
Vergne I, Chua J, Deretic V. Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade. The Journal of Experimental Medicine. 198: 653-9. PMID 12925680 DOI: 10.1084/Jem.20030527 |
0.615 |
|
| 2003 |
Vergne I, Chua J, Deretic V. Mycobacterium tuberculosis phagosome maturation arrest: selective targeting of PI3P-dependent membrane trafficking. Traffic (Copenhagen, Denmark). 4: 600-6. PMID 12911814 DOI: 10.1034/J.1600-0854.2003.00120.X |
0.613 |
|
| 2003 |
Fratti RA, Chua J, Vergne I, Deretic V. Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest. Proceedings of the National Academy of Sciences of the United States of America. 100: 5437-42. PMID 12702770 DOI: 10.1073/Pnas.0737613100 |
0.753 |
|
| 2003 |
Kremer L, Dover LG, Morbidoni HR, Vilchèze C, Maughan WN, Baulard A, Tu SC, Honoré N, Deretic V, Sacchettini JC, Locht C, Jacobs WR, Besra GS. Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria. The Journal of Biological Chemistry. 278: 20547-54. PMID 12654922 DOI: 10.1074/Jbc.M302435200 |
0.329 |
|
| 2003 |
Firoved AM, Deretic V. Microarray analysis of global gene expression in mucoid Pseudomonas aeruginosa. Journal of Bacteriology. 185: 1071-81. PMID 12533483 DOI: 10.1128/Jb.185.3.1071-1081.2003 |
0.814 |
|
| 2002 |
Poschet J, Perkett E, Deretic V. Hyperacidification in cystic fibrosis: links with lung disease and new prospects for treatment. Trends in Molecular Medicine. 8: 512-9. PMID 12421684 DOI: 10.1016/S1471-4914(02)02414-0 |
0.366 |
|
| 2002 |
Master SS, Springer B, Sander P, Boettger EC, Deretic V, Timmins GS. Oxidative stress response genes in Mycobacterium tuberculosis: role of ahpC in resistance to peroxynitrite and stage-specific survival in macrophages. Microbiology (Reading, England). 148: 3139-44. PMID 12368447 DOI: 10.1099/00221287-148-10-3139 |
0.414 |
|
| 2002 |
Zahrt TC, Deretic V. Reactive nitrogen and oxygen intermediates and bacterial defenses: unusual adaptations in Mycobacterium tuberculosis. Antioxidants & Redox Signaling. 4: 141-59. PMID 11970850 DOI: 10.1089/152308602753625924 |
0.376 |
|
| 2002 |
Fratti RA, Chua J, Deretic V. Cellubrevin alterations and Mycobacterium tuberculosis phagosome maturation arrest. The Journal of Biological Chemistry. 277: 17320-6. PMID 11825909 DOI: 10.1074/Jbc.M200335200 |
0.772 |
|
| 2002 |
Poschet JF, Skidmore J, Boucher JC, Firoved AM, Van Dyke RW, Deretic V. Hyperacidification of cellubrevin endocytic compartments and defective endosomal recycling in cystic fibrosis respiratory epithelial cells. The Journal of Biological Chemistry. 277: 13959-65. PMID 11809765 DOI: 10.1074/Jbc.M105441200 |
0.773 |
|
| 2002 |
Firoved AM, Boucher JC, Deretic V. Global genomic analysis of AlgU (sigma(E))-dependent promoters (sigmulon) in Pseudomonas aeruginosa and implications for inflammatory processes in cystic fibrosis. Journal of Bacteriology. 184: 1057-64. PMID 11807066 DOI: 10.1128/Jb.184.4.1057-1064.2002 |
0.802 |
|
| 2002 |
Zahrt TC, Deretic V. Regulatory Systems Controlling Latent Infection by Mycobacterium tuberculosis Directions in Science. 1: 103-106. DOI: 10.1100/Tsw.2002.860 |
0.33 |
|
| 2001 |
Poschet JF, Boucher JC, Tatterson L, Skidmore J, Van Dyke RW, Deretic V. Molecular basis for defective glycosylation and Pseudomonas pathogenesis in cystic fibrosis lung. Proceedings of the National Academy of Sciences of the United States of America. 98: 13972-7. PMID 11717455 DOI: 10.1073/Pnas.241182598 |
0.757 |
|
| 2001 |
Zahrt TC, Deretic V. Mycobacterium tuberculosis signal transduction system required for persistent infections. Proceedings of the National Academy of Sciences of the United States of America. 98: 12706-11. PMID 11675502 DOI: 10.1073/Pnas.221272198 |
0.38 |
|
| 2001 |
Springer B, Master S, Sander P, Zahrt T, McFalone M, Song J, Papavinasasundaram KG, Colston MJ, Boettger E, Deretic V. Silencing of oxidative stress response in Mycobacterium tuberculosis: expression patterns of ahpC in virulent and avirulent strains and effect of ahpC inactivation. Infection and Immunity. 69: 5967-73. PMID 11553532 DOI: 10.1128/Iai.69.10.5967-5973.2001 |
0.426 |
|
| 2001 |
Fratti RA, Backer JM, Gruenberg J, Corvera S, Deretic V. Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest. The Journal of Cell Biology. 154: 631-44. PMID 11489920 DOI: 10.1083/Jcb.200106049 |
0.72 |
|
| 2001 |
Tatterson LE, Poschet JF, Firoved A, Skidmore J, Deretic V. CFTR and pseudomonas infections in cystic fibrosis. Frontiers in Bioscience : a Journal and Virtual Library. 6: D890-7. PMID 11487480 DOI: 10.2741/Tatterso |
0.796 |
|
| 2001 |
Pym AS, Domenech P, Honoré N, Song J, Deretic V, Cole ST. Regulation of catalase-peroxidase (KatG) expression, isoniazid sensitivity and virulence by furA of Mycobacterium tuberculosis. Molecular Microbiology. 40: 879-89. PMID 11401695 DOI: 10.1046/J.1365-2958.2001.02427.X |
0.438 |
|
| 2001 |
Poschet JF, Boucher JC, Firoved AM, Deretic V. Conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients. Methods in Enzymology. 336: 65-76. PMID 11398420 DOI: 10.1016/S0076-6879(01)36579-5 |
0.804 |
|
| 2001 |
Master S, Zahrt TC, Song J, Deretic V. Mapping of Mycobacterium tuberculosis katG promoters and their differential expression in infected macrophages Journal of Bacteriology. 183: 4033-4039. PMID 11395468 DOI: 10.1128/Jb.183.13.4033-4039.2001 |
0.453 |
|
| 2001 |
Zahrt TC, Song J, Siple J, Deretic V. Mycobacterial FurA is a negative regulator of catalase-peroxidase gene katG Molecular Microbiology. 39: 1174-1185. PMID 11251835 DOI: 10.1111/J.1365-2958.2001.02321.X |
0.422 |
|
| 2000 |
Fratti RA, Vergne I, Chua J, Skidmore J, Deretic V. Regulators of membrane trafficking and Mycobacterium tuberculosis phagosome maturation block. Electrophoresis. 21: 3378-85. PMID 11079558 DOI: 10.1002/1522-2683(20001001)21:16<3378::Aid-Elps3378>3.0.Co;2-B |
0.768 |
|
| 2000 |
Zahrt TC, Deretic V. An essential two-component signal transduction system in Mycobacterium tuberculosis Journal of Bacteriology. 182: 3832-3838. PMID 10851001 DOI: 10.1128/Jb.182.13.3832-3838.2000 |
0.404 |
|
| 2000 |
Boucher JC, Schurr MJ, Deretic V. Dual regulation of mucoidy in Pseudomonas aeruginosa and sigma factor antagonism. Molecular Microbiology. 36: 341-51. PMID 10792721 DOI: 10.1046/J.1365-2958.2000.01846.X |
0.763 |
|
| 2000 |
Rowen DW, Deretic V. Membrane-to-cytosol redistribution of ECF sigma factor AlgU and conversion to mucoidy in Pseudomonas aeruginosa isolates from cystic fibrosis patients Molecular Microbiology. 36: 314-327. PMID 10792719 DOI: 10.1046/J.1365-2958.2000.01830.X |
0.403 |
|
| 2000 |
Yu H, Nasr SZ, Deretic V. Innate lung defenses and compromised Pseudomonas aeruginosa clearance in the malnourished mouse model of respiratory infections in cystic fibrosis. Infection and Immunity. 68: 2142-7. PMID 10722612 DOI: 10.1128/Iai.68.4.2142-2147.2000 |
0.365 |
|
| 1999 |
Deretic V, Fratti RA. Mycobacterium tuberculosis phagosome. Molecular Microbiology. 31: 1603-9. PMID 10209735 DOI: 10.1046/J.1365-2958.1999.01279.X |
0.702 |
|
| 1999 |
Garbe TR, Hibler NS, Deretic V. Response to reactive nitrogen intermediates in Mycobacterium tuberculosis: Induction of the 16-kilodalton α-crystallin homolog by exposure to nitric oxide donors Infection and Immunity. 67: 460-465. PMID 9864257 DOI: 10.1128/Iai.67.1.460-465.1999 |
0.322 |
|
| 1998 |
Pagán-Ramos E, Song J, McFalone M, Mudd MH, Deretic V. Oxidative stress response and characterization of the oxyR-ahpC and furA-katG loci in Mycobacterium marinum Journal of Bacteriology. 180: 4856-4864. PMID 9733688 DOI: 10.1128/Jb.180.18.4856-4864.1998 |
0.377 |
|
| 1998 |
Via LE, Fratti RA, McFalone M, Pagan-Ramos E, Deretic D, Deretic V. Effects of cytokines on mycobacterial phagosome maturation. Journal of Cell Science. 111: 897-905. PMID 9490634 |
0.641 |
|
| 1998 |
Yu H, Hanes M, Chrisp CE, Boucher JC, Deretic V. Microbial pathogenesis in cystic fibrosis: pulmonary clearance of mucoid Pseudomonas aeruginosa and inflammation in a mouse model of repeated respiratory challenge. Infection and Immunity. 66: 280-8. PMID 9423869 DOI: 10.1128/Iai.66.1.280-288.1998 |
0.734 |
|
| 1998 |
Yu H, Boucher JC, Deretic V. 7.5 Molecular Analysis of Pseudomonas Aeruginosa Virulence Methods in Microbiology. 27: 383-393. DOI: 10.1016/S0580-9517(08)70299-X |
0.767 |
|
| 1997 |
Deretic V, Via LE, Fratti RA, Deretic D. Mycobacterial phagosome maturation, rab proteins, and intracellular trafficking. Electrophoresis. 18: 2542-7. PMID 9527483 DOI: 10.1002/Elps.1150181409 |
0.701 |
|
| 1997 |
Boucher JC, Schurr MJ, Yu H, Rowen DW, Deretic V. Pseudomonas aeruginosa in cystic fibrosis: role of mucC in the regulation of alginate production and stress sensitivity. Microbiology (Reading, England). 143: 3473-80. PMID 9387225 DOI: 10.1099/00221287-143-11-3473 |
0.771 |
|
| 1997 |
Deretic V, Song J, Pagán-Ramos E. Loss of oxyR in Mycobacterium tuberculosis Trends in Microbiology. 5: 367-372. PMID 9294894 DOI: 10.1016/S0966-842X(97)01112-8 |
0.355 |
|
| 1997 |
Boucher JC, Yu H, Mudd MH, Deretic V. Mucoid Pseudomonas aeruginosa in cystic fibrosis: characterization of muc mutations in clinical isolates and analysis of clearance in a mouse model of respiratory infection. Infection and Immunity. 65: 3838-46. PMID 9284161 DOI: 10.1128/Iai.65.9.3838-3846.1997 |
0.767 |
|
| 1997 |
Schurr MJ, Deretic V. Microbial pathogenesis in cystic fibrosis: Co-ordinate regulation of heat-shock response and conversion to mucoidy in Pseudomonas aeruginosa Molecular Microbiology. 24: 411-420. PMID 9159526 DOI: 10.1046/J.1365-2958.1997.3411711.X |
0.44 |
|
| 1997 |
Via LE, Deretic D, Ulmer RJ, Hibler NS, Huber LA, Deretic V. Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7 Journal of Biological Chemistry. 272: 13326-13331. PMID 9148954 DOI: 10.1074/Jbc.272.20.13326 |
0.381 |
|
| 1997 |
Dhandayuthapani S, Mudd M, Deretic V. Interactions of OxyR with the promoter region of the OxyR and ahpC genes from Mycobacterium leprae and Mycobacterium tuberculosis Journal of Bacteriology. 179: 2401-2409. PMID 9079928 DOI: 10.1128/Jb.179.7.2401-2409.1997 |
0.36 |
|
| 1997 |
Sreevatsan S, Pan X, Zhang Y, Deretic V, Musser JM. Analysis of the oxyR-ahpC region in isoniazid-resistant and - susceptible Mycobacterium tuberculosis complex organisms recovered from diseased humans and animals in diverse localities Antimicrobial Agents and Chemotherapy. 41: 600-606. PMID 9056000 DOI: 10.1128/Aac.41.3.600 |
0.311 |
|
| 1997 |
Yu H, Mudd M, Boucher JC, Schurr MJ, Deretic V. Identification of the algZ gene upstream of the response regulator algR and its participation in control of alginate production in Pseudomonas aeruginosa. Journal of Bacteriology. 179: 187-93. PMID 8981997 DOI: 10.1128/Jb.179.1.187-193.1997 |
0.764 |
|
| 1996 |
Deretic V, Pagán-Ramos E, Zhang Y, Dhandayuthapani S, Via LE. The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid Nature Biotechnology. 14: 1557-1561. PMID 9634820 DOI: 10.1038/Nbt1196-1557 |
0.362 |
|
| 1996 |
Zhang Y, Dhandayuthapani S, Deretic V. Molecular basis for the exquisite sensitivity of Mycobacterium tuberculosis to isoniazid Proceedings of the National Academy of Sciences of the United States of America. 93: 13212-13216. PMID 8917570 DOI: 10.1073/Pnas.93.23.13212 |
0.372 |
|
| 1996 |
Garbe TR, Hibler NS, Deretic V. Response of Mycobacterium tuberculosis to reactive oxygen and nitrogen intermediates Molecular Medicine. 2: 134-142. PMID 8900541 DOI: 10.1007/Bf03402209 |
0.329 |
|
| 1996 |
Govan JRW, Deretic V. Microbial pathogenesis in cystic fibrosis: Mucoid Pseudomonas aeruginosa and Burkholderia cepacia Microbiological Reviews. 60: 539-574. PMID 8840786 DOI: 10.1128/Mmbr.60.3.539-574.1996 |
0.426 |
|
| 1996 |
Garbe TR, Hibler NS, Deretic V. Isoniazid induces expression of the antigen 85 complex in Mycobacterium tuberculosis Antimicrobial Agents and Chemotherapy. 40: 1754-1756. PMID 8807080 DOI: 10.1128/Aac.40.7.1754 |
0.341 |
|
| 1996 |
Schurr MJ, Yu H, Martinez-Salazar JM, Boucher JC, Deretic V. Control of AlgU, a member of the sigma E-like family of stress sigma factors, by the negative regulators MucA and MucB and Pseudomonas aeruginosa conversion to mucoidy in cystic fibrosis. Journal of Bacteriology. 178: 4997-5004. PMID 8759866 DOI: 10.1128/Jb.178.16.4997-5004.1996 |
0.774 |
|
| 1996 |
Yu H, Boucher JC, Hibler NS, Deretic V. Virulence properties of Pseudomonas aeruginosa lacking the extreme-stress sigma factor AlgU (sigmaE). Infection and Immunity. 64: 2774-81. PMID 8698507 DOI: 10.1128/Iai.64.7.2774-2781.1996 |
0.776 |
|
| 1996 |
Dhandayuthapani S, Zhang Y, Mudd MH, Deretic V. Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: Characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis Journal of Bacteriology. 178: 3641-3649. PMID 8655566 DOI: 10.1128/Jb.178.12.3641-3649.1996 |
0.356 |
|
| 1996 |
Via LE, Curcic R, Mudd MH, Dhandayuthapani S, Ulmer RJ, Deretic V. Elements of signal transduction in Mycobacterium tuberculosis: In vitro phosphorylation and in vivo expression of the response regulator MtrA Journal of Bacteriology. 178: 3314-3321. PMID 8655513 DOI: 10.1128/Jb.178.11.3314-3321.1996 |
0.395 |
|
| 1996 |
Martínez-Salazar JM, Moreno S, Nájera R, Boucher JC, Espín G, Soberón-Chávez G, Deretic V. Characterization of the genes coding for the putative sigma factor AlgU and its regulators MucA, MucB, MucC, and MucD in Azotobacter vinelandii and evaluation of their roles in alginate biosynthesis. Journal of Bacteriology. 178: 1800-8. PMID 8606151 DOI: 10.1128/Jb.178.7.1800-1808.1996 |
0.737 |
|
| 1996 |
Boucher JC, Martinez-Salazar J, Schurr MJ, Mudd MH, Yu H, Deretic V. Two distinct loci affecting conversion to mucoidy in Pseudomonas aeruginosa in cystic fibrosis encode homologs of the serine protease HtrA. Journal of Bacteriology. 178: 511-23. PMID 8550474 DOI: 10.1128/Jb.178.2.511-523.1996 |
0.763 |
|
| 1995 |
Dhandayuthapani S, Via LE, Thomas CA, Horowitz PM, Deretic D, Deretic V. Green fluorescent protein as a marker for gene expression and cell biology of mycobacterial interactions with macrophages. Molecular Microbiology. 17: 901-12. PMID 8596439 DOI: 10.1111/J.1365-2958.1995.Mmi_17050901.X |
0.387 |
|
| 1995 |
Deretic V, Philipp W, Dhandayuthapani S, Mudd MH, Curcic R, Garbe T, Heym B, Via LE, Cole ST. Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: Implications for sensitivity to isoniazid Molecular Microbiology. 17: 889-900. PMID 8596438 DOI: 10.1111/J.1365-2958.1995.Mmi_17050889.X |
0.382 |
|
| 1995 |
Deretic V, Schurr MJ, Yu H. Pseudomonas aeruginosa, mucoidy and the chronic infection phenotype in cystic fibrosis Trends in Microbiology. 3: 351-356. PMID 8520888 DOI: 10.1016/S0966-842X(00)88974-X |
0.391 |
|
| 1995 |
Yu H, Schurr MJ, Deretic V. Functional equivalence of Escherichia coli σ(E) and Pseudomonas aeruginosa AlgU: E. coli rpoE restores mucoidy and reduces sensitivity to reactive oxygen intermediates in algU mutants of P. aeruginosa Journal of Bacteriology. 177: 3259-3268. PMID 7768826 DOI: 10.1128/Jb.177.11.3259-3268.1995 |
0.421 |
|
| 1995 |
Schurr MJ, Yu H, Boucher JC, Hibler NS, Deretic V. Multiple promoters and induction by heat shock of the gene encoding the alternative sigma factor AlgU (sigma E) which controls mucoidy in cystic fibrosis isolates of Pseudomonas aeruginosa. Journal of Bacteriology. 177: 5670-9. PMID 7559357 DOI: 10.1128/Jb.177.19.5670-5679.1995 |
0.757 |
|
| 1995 |
Schurr MJ, Yu H, Martinez-Salazar JM, Hibler NS, Deretic V. Biochemical characterization and posttranslational modification of AlgU, a regulator of stress response in Pseudomonas aeruginosa Biochemical and Biophysical Research Communications. 216: 874-880. PMID 7488207 DOI: 10.1006/Bbrc.1995.2703 |
0.31 |
|
| 1994 |
Schurr MJ, Martin DW, Mudd MH, Deretic V. Gene cluster controlling conversion to alginate-overproducing phenotype in Pseudomonas aeruginosa: Functional analysis in a heterologous host and role in the instability of mucoidy Journal of Bacteriology. 176: 3375-3382. PMID 8195094 DOI: 10.1128/Jb.176.11.3375-3382.1994 |
0.384 |
|
| 1994 |
Deretic V, Schurr MJ, Boucher JC, Martin DW. Conversion of Pseudomonas aeruginosa to mucoidy in cystic fibrosis: environmental stress and regulation of bacterial virulence by alternative sigma factors. Journal of Bacteriology. 176: 2773-80. PMID 8188579 DOI: 10.1128/Jb.176.10.2773-2780.1994 |
0.749 |
|
| 1994 |
Mohr CD, Sonsteby SK, Deretic V. The Pseudomonas aeruginosa homologs of hemC and hemD are linked to the gene encoding the regulator of mucoidy AlgR Mgg Molecular & General Genetics. 242: 177-184. PMID 8159168 DOI: 10.1007/Bf00391011 |
0.433 |
|
| 1994 |
Martin DW, Schurr MJ, Yu H, Deretic V. Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: Relationship to σ(E) and stress response Journal of Bacteriology. 176: 6688-6696. PMID 7961422 DOI: 10.1128/Jb.176.21.6688-6696.1994 |
0.402 |
|
| 1993 |
Martin DW, Holloway BW, Deretic V. Characterization of a locus determining the mucoid status of Pseudomonas aeruginosa: AlgU shows sequence similarities with a Bacillus sigma factor Journal of Bacteriology. 175: 1153-1164. PMID 8432708 DOI: 10.1128/Jb.175.4.1153-1164.1993 |
0.381 |
|
| 1993 |
Martin DW, Schurr MJ, Mudd MH, Deretic V. Differentiation of Pseudomonas aeruginosa into the alginate-producing form: Inactivation of mucB causes conversion to mucoidy Molecular Microbiology. 9: 497-506. PMID 8412698 DOI: 10.1111/J.1365-2958.1993.Tb01711.X |
0.431 |
|
| 1993 |
Martin DW, Schurr MJ, Mudd MH, Govan JRW, Holloway BW, Deretic V. Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients Proceedings of the National Academy of Sciences of the United States of America. 90: 8377-8381. PMID 8378309 |
0.339 |
|
| 1993 |
Schurr MJ, Martin DW, Mudd MH, Hibler NS, Boucher JC, Deretic V. The algD promoter: regulation of alginate production by Pseudomonas aeruginosa in cystic fibrosis. Cellular & Molecular Biology Research. 39: 371-6. PMID 8312973 |
0.753 |
|
| 1993 |
Deretic V, Martin DW, Schurr MJ, Mudd MH, Hibler NS, Curcic R, Boucher JC. Conversion to mucoidy in Pseudomonas aeruginosa. Bio/Technology (Nature Publishing Company). 11: 1133-6. PMID 7764093 DOI: 10.1038/Nbt1093-1133 |
0.763 |
|
| 1993 |
Francetić O, Marjanović N, Deretic V, Glišin V. Host dependenet inactivation by IS2 of induced E.coli penicillin amidase gene cloned on multicopy plasmids Biotechnology Letters. 15: 7-12. DOI: 10.1007/Bf00131544 |
0.351 |
|
| 1992 |
Deretic V, Hibler NS, Holt SC. Immunocytochemical analysis of AlgP (H(p)1), a histonelike element participating in control of mucoidy in Pseudomonas aeruginosa Journal of Bacteriology. 174: 824-831. PMID 1732216 DOI: 10.1128/Jb.174.3.824-831.1992 |
0.393 |
|
| 1992 |
Govan JRW, Martin DW, Deretic VP. Mucoid Pseudomonas aeruginosa and cystic fibrosis: The role of mutations in muc loci Fems Microbiology Letters. 100: 323-329. PMID 1478467 DOI: 10.1016/0378-1097(92)90228-G |
0.315 |
|
| 1992 |
Deretic V, Leveau JHJ, Mohr CD, Hibler NS. In vitro phosphorylation of AlgR, a regulator of mucoidy in Pseudomonas aeruginosa, by a histidine protein kinase and effects of small phospho-donor molecules Molecular Microbiology. 6: 2761-2767. PMID 1435255 DOI: 10.1111/J.1365-2958.1992.Tb01455.X |
0.362 |
|
| 1991 |
Deretic V, Mohr CD, Martin DW. Mucoid Pseudomonas aeruginosa in cystic fibrosis: Signal transduction and histone-like elements in the regulation of bacterial virulence Molecular Microbiology. 5: 1577-1583. PMID 1943693 DOI: 10.1111/J.1365-2958.1991.Tb01903.X |
0.406 |
|
| 1990 |
Deretic V, Govan JRW, Konyecsni WM, Martin DW. Mucoid Pseudomonas aeruginosa in cystic fibrosis: Mutations in the muc loci affect transcription of the algR and algD genes in response to environmental stimuli Molecular Microbiology. 4: 189-196. PMID 2140147 DOI: 10.1111/J.1365-2958.1990.Tb00586.X |
0.419 |
|
| 1990 |
Mohr CD, Rust L, Albus AM, Iglewski BH, Deretic V. Expression patterns of genes encoding elastase and controlling mucoidy: Co-ordinate regulation of two virulence factors in Pseudomonas aeruginosa isolates from cystic fibrosis Molecular Microbiology. 4: 2103-2110. PMID 2128528 DOI: 10.1111/J.1365-2958.1990.Tb00571.X |
0.43 |
|
| 1990 |
Mohr CD, Martin DW, Konyecsni WM, Govan JRW, Lory S, Deretic V. Role of the far-upstream sites of the algD promoter and the algR and rpoN genes in environmental modulation of mucoidy in Pseudomonas aeruginosa Journal of Bacteriology. 172: 6576-6580. PMID 2121718 DOI: 10.1128/Jb.172.11.6576-6580.1990 |
0.337 |
|
| 1990 |
Mohr CD, Deretic V. Gene-scrambling mutagenesis: Generation and analysis of insertional mutations in the alginate regulatory region of Pseudomonas aeruginosa Journal of Bacteriology. 172: 6252-6260. PMID 2121708 DOI: 10.1128/Jb.172.11.6252-6260.1990 |
0.343 |
|
| 1990 |
Konyecsni WM, Deretic V. DNA sequence and expression analysis of algP and algQ, components of the multigene system transcriptionally regulating mucoidy in Pseudonomas aeruginosa: algP contains multiple direct repeats Journal of Bacteriology. 172: 2511-2520. PMID 2110144 DOI: 10.1128/Jb.172.5.2511-2520.1990 |
0.379 |
|
| 1990 |
Deretic V, Konyecsni WM. A procaryotic regulatory factor with a histone H1-like carboxy-terminal domain: Clonal variation of repeats within algP, a gene involved in regulation of mucoidy in Pseudomonas aeruginosa Journal of Bacteriology. 172: 5544-5554. PMID 1698761 DOI: 10.1128/Jb.172.10.5544-5554.1990 |
0.342 |
|
| 1989 |
Deretic V, Konyecsni WM. Control of mucoidy in Pseudomonas aeruginosa: Transcriptional regulation of algR and identification of the second regulatory gene, algQ Journal of Bacteriology. 171: 3680-3688. PMID 2544550 DOI: 10.1128/Jb.171.7.3680-3688.1989 |
0.397 |
|
| 1989 |
Deretic V, Dikshit R, Konyecsni WM, Chakrabarty AM, Misra TK. The algR gene, which regulates mucoidy in Pseudomonas aeruginosa, belongs to a class of environmentally responsive genes Journal of Bacteriology. 171: 1278-1283. PMID 2493441 DOI: 10.1128/Jb.171.3.1278-1283.1989 |
0.4 |
|
| 1989 |
Deretic V, Konyecsni WM, Mohr CD, Martin DW, Hibler NS. Common denominators of promoter control in Pseudomonas and other bacteria Bio/Technology. 7: 1249-1254. DOI: 10.1038/Nbt1289-1249 |
0.358 |
|
| 1988 |
Konyecsni WM, Deretic V. Broad-host-range plasmid and M13 bacteriophage-derived vectors for promoter analysis in Escherichia coli and Pseudomonas aeruginosa Gene. 74: 375-386. PMID 3149945 DOI: 10.1016/0378-1119(88)90171-0 |
0.407 |
|
| 1987 |
Deretic V, Chandrasekharappa S, Gill JF, Chatterjee DK, Chakrabarty AM. A set of cassettes and improved vectors for genetic and biochemical characterization of pseudomonas genes Gene. 57: 61-72. PMID 3123327 DOI: 10.1016/0378-1119(87)90177-6 |
0.309 |
|
| 1987 |
Deretic V, Gill JF, Chakrabarty AM. Pseudomonas aeruginosa infection in cystic fibrosis: Nucleotide sequence and transcriptional regulation of the algD gene Nucleic Acids Research. 15: 4567-4581. PMID 3108855 DOI: 10.1093/Nar/15.11.4567 |
0.441 |
|
| 1987 |
Deretic V, Gill JF, Chakrabarty AM. Gene algD coding for GDPmannose dehydrogenase is transcriptionally activated in mucoid Pseudomonas aeruginosa Journal of Bacteriology. 169: 351-358. PMID 3025179 DOI: 10.1128/Jb.169.1.351-358.1987 |
0.371 |
|
| 1987 |
Deretic V, Gill JF, Chakrabarty AM. Alginate biosynthesis: A model system for gene regulation and function in pseudomonas Bio/Technology. 5: 469-477. DOI: 10.1038/Nbt0587-469 |
0.401 |
|
| 1986 |
Gill JF, Deretic V, Chakrabarty AM. Overproduction and assay of Pseudomonas aeruginosa phosphomannose isomerase Journal of Bacteriology. 167: 611-615. PMID 2426246 DOI: 10.1128/Jb.167.2.611-615.1986 |
0.386 |
|
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