| Year |
Citation |
Score |
| 2022 |
Patange S, Ball DA, Wan Y, Karpova TS, Girvan M, Levens D, Larson DR. MYC amplifies gene expression through global changes in transcription factor dynamics. Cell Reports. 38: 110292. PMID 35081348 DOI: 10.1016/j.celrep.2021.110292 |
0.321 |
|
| 2021 |
Wan Y, Anastasakis DG, Rodriguez J, Palangat M, Gudla P, Zaki G, Tandon M, Pegoraro G, Chow CC, Hafner M, Larson DR. Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection. Cell. PMID 33979654 DOI: 10.1016/j.cell.2021.04.012 |
0.311 |
|
| 2021 |
Patange S, Ball DA, Karpova TS, Larson DR. Towards a 'Spot On' Understanding of Transcription in the Nucleus. Journal of Molecular Biology. 433: 167016. PMID 33951451 DOI: 10.1016/j.jmb.2021.167016 |
0.327 |
|
| 2020 |
Rodriguez J, Larson DR. Transcription in Living Cells: Molecular Mechanisms of Bursting. Annual Review of Biochemistry. PMID 32208766 DOI: 10.1146/Annurev-Biochem-011520-105250 |
0.411 |
|
| 2020 |
Larson DR. Dynamic Imaging of Nascent RNA Reveals General Principles of Transcription and Splicing Biophysical Journal. 118: 4a. DOI: 10.1016/J.Bpj.2019.11.216 |
0.391 |
|
| 2019 |
Donovan BT, Huynh A, Ball DA, Patel HP, Poirier MG, Larson DR, Ferguson ML, Lenstra TL. Live-cell imaging reveals the interplay between transcription factors, nucleosomes, and bursting. The Embo Journal. PMID 31101674 DOI: 10.15252/Embj.2018100809 |
0.66 |
|
| 2019 |
Malik N, Yan H, Moshkovich N, Palangat M, Yang H, Sanchez V, Cai Z, Peat TJ, Jiang S, Liu C, Lee M, Mock BA, Yuspa SH, Larson D, Wakefield LM, et al. The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription. Nature Communications. 10: 2071. PMID 31061501 DOI: 10.1038/S41467-019-10102-6 |
0.353 |
|
| 2019 |
Palangat M, Anastasakis DG, Fei DL, Lindblad KE, Bradley R, Hourigan CS, Hafner M, Larson DR. The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation. Genes & Development. PMID 30842218 DOI: 10.1101/Gad.319590.118 |
0.31 |
|
| 2019 |
Patange S, Girvan M, Levens D, Larson DR. A Living, Single Cell View of Myc's Effects on Transcription Biophysical Journal. 116: 306a-307a. DOI: 10.1016/J.Bpj.2018.11.1661 |
0.377 |
|
| 2018 |
Rodriguez J, Ren G, Day CR, Zhao K, Chow CC, Larson DR. Intrinsic Dynamics of a Human Gene Reveal the Basis of Expression Heterogeneity. Cell. PMID 30554876 DOI: 10.1016/J.Cell.2018.11.026 |
0.392 |
|
| 2018 |
Wan Y, Larson DR. Splicing heterogeneity: separating signal from noise. Genome Biology. 19: 86. PMID 29986741 DOI: 10.1186/S13059-018-1467-4 |
0.347 |
|
| 2018 |
Tsai PF, Dell'Orso S, Rodriguez J, Vivanco KO, Ko KD, Jiang K, Juan AH, Sarshad AA, Vian L, Tran M, Wangsa D, Wang AH, Perovanovic J, Anastasakis D, Ralston E, ... ... Larson DR, et al. A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans. Molecular Cell. 71: 129-141.e8. PMID 29979962 DOI: 10.1016/J.Molcel.2018.06.008 |
0.378 |
|
| 2018 |
Patange S, Girvan M, Larson DR. Single-cell systems biology: probing the basic unit of information flow. Current Opinion in Systems Biology. 8: 7-15. PMID 29552672 DOI: 10.1016/J.Coisb.2017.11.011 |
0.371 |
|
| 2018 |
Huynh A, Buckmiller M, Larson DR, Lenstra T, Ferguson ML. A Study of Transcriptional Activation by the Transcription Factor GAL4 in Saccharomyces Cerevisiae by 3D Orbital Tracking and In Vivo RNA Labelling Biophysical Journal. 114: 205a. DOI: 10.1016/J.Bpj.2017.11.1143 |
0.646 |
|
| 2017 |
Ren G, Jin W, Cui K, Rodrigez J, Hu G, Zhang Z, Larson DR, Zhao K. CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression. Molecular Cell. 67: 1049-1058.e6. PMID 28938092 DOI: 10.1016/J.Molcel.2017.08.026 |
0.357 |
|
| 2017 |
Hendy O, Campbell J, Weissman JD, Larson DR, Singer DS. Differential, context specific, impact of individual core promoter elements on transcriptional dynamics. Molecular Biology of the Cell. PMID 28931597 DOI: 10.1091/Mbc.E17-06-0408 |
0.332 |
|
| 2017 |
Das S, Parker JM, Guven C, Wang W, Kriebel PW, Losert W, Larson DR, Parent CA. Adenylyl cyclase mRNA localizes to the posterior of polarized DICTYOSTELIUM cells during chemotaxis. Bmc Cell Biology. 18: 23. PMID 28545392 DOI: 10.1186/S12860-017-0139-7 |
0.493 |
|
| 2017 |
Patange S, Girvan M, Levens D, Larson DR. Single Molecule Analysis of Transcription in Live Cells Reveals the Gene Regulatory Function of MYC In Vivo Biophysical Journal. 112: 210a-211a. DOI: 10.1016/J.Bpj.2016.11.1162 |
0.485 |
|
| 2016 |
Chen H, Larson DR. What have single-molecule studies taught us about gene expression? Genes & Development. 30: 1796-810. PMID 27601529 DOI: 10.1101/Gad.281725.116 |
0.412 |
|
| 2016 |
Lenstra TL, Rodriguez J, Chen H, Larson DR. Transcription Dynamics in Living Cells. Annual Review of Biophysics. PMID 27145880 DOI: 10.1146/Annurev-Biophys-062215-010838 |
0.405 |
|
| 2016 |
Lenstra TL, Larson DR. Single-Molecule mRNA Detection in Live Yeast. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 113: 14.24.1-14.24.15. PMID 27110320 DOI: 10.1002/0471142727.Mb1424S113 |
0.447 |
|
| 2016 |
Palangat M, Larson DR. Single-Gene Dual-Color Reporter Cell Line to Analyze RNA Synthesis in vivo. Methods (San Diego, Calif.). PMID 27068658 DOI: 10.1016/J.Ymeth.2016.04.009 |
0.433 |
|
| 2015 |
Day CR, Chen H, Coulon A, Meier JL, Larson DR. High-throughput single-molecule screen for small-molecule perturbation of splicing and transcription kinetics. Methods (San Diego, Calif.). PMID 26655523 DOI: 10.1016/J.Ymeth.2015.11.025 |
0.438 |
|
| 2015 |
Lenstra TL, Coulon A, Chow CC, Larson DR. Single-Molecule Imaging Reveals a Switch between Spurious and Functional ncRNA Transcription. Molecular Cell. PMID 26549684 DOI: 10.1016/J.Molcel.2015.09.028 |
0.414 |
|
| 2015 |
Coulon A, Lenstra TL, Chow CC, Larson DR. Live-Cell Single-Molecule Imaging of Sense and Antisense Transcription of a Yeast Gene Biophysical Journal. 108: 536a. DOI: 10.1016/J.Bpj.2014.11.2937 |
0.475 |
|
| 2015 |
Larson D. Understanding Gene Expression Heterogeneity in Living Cells with Single-Molecule Fluorescence Microscopy Biophysical Journal. 108: 8a. DOI: 10.1016/J.Bpj.2014.11.064 |
0.46 |
|
| 2014 |
Chen J, Grunwald D, Sardo L, Galli A, Plisov S, Nikolaitchik OA, Chen D, Lockett S, Larson DR, Pathak VK, Hu WS. Cytoplasmic HIV-1 RNA is mainly transported by diffusion in the presence or absence of Gag protein. Proceedings of the National Academy of Sciences of the United States of America. 111: E5205-13. PMID 25404326 DOI: 10.1073/Pnas.1413169111 |
0.324 |
|
| 2014 |
Coulon A, Ferguson ML, de Turris V, Palangat M, Chow CC, Larson DR. Kinetic competition during the transcription cycle results in stochastic RNA processing. Elife. 3. PMID 25271374 DOI: 10.7554/Elife.03939 |
0.664 |
|
| 2014 |
Levens D, Larson DR. A new twist on transcriptional bursting. Cell. 158: 241-2. PMID 25036624 DOI: 10.1016/J.Cell.2014.06.042 |
0.324 |
|
| 2014 |
Coulon A, Ferguson ML, Turris Vd, Palangat M, Chow CC, Larson DR. Author response: Kinetic competition during the transcription cycle results in stochastic RNA processing Elife. DOI: 10.7554/Elife.03939.031 |
0.628 |
|
| 2014 |
Ferguson ML, Coulon A, de Turris V, Palangat M, Chow CC, Larson DR. Single Molecule Imaging In Vivo Determines Post-Transcriptional RNA Processing Dynamics Biophysical Journal. 106: 223a. DOI: 10.1016/J.Bpj.2013.11.1305 |
0.668 |
|
| 2013 |
Larson DR, Fritzsch C, Sun L, Meng X, Lawrence DS, Singer RH. Direct observation of frequency modulated transcription in single cells using light activation. Elife. 2: e00750. PMID 24069527 DOI: 10.7554/Elife.00750 |
0.323 |
|
| 2013 |
Ferguson ML, Larson DR. Measuring transcription dynamics in living cells using fluctuation analysis. Methods in Molecular Biology (Clifton, N.J.). 1042: 47-60. PMID 23979999 DOI: 10.1007/978-1-62703-526-2_4 |
0.7 |
|
| 2013 |
Coulon A, Chow CC, Singer RH, Larson DR. Eukaryotic transcriptional dynamics: from single molecules to cell populations. Nature Reviews. Genetics. 14: 572-84. PMID 23835438 DOI: 10.1038/Nrg3484 |
0.42 |
|
| 2013 |
Larson DR, Fritzsch C, Sun L, Meng X, Lawrence DS, Singer RH. Author response: Direct observation of frequency modulated transcription in single cells using light activation Elife. DOI: 10.7554/Elife.00750.024 |
0.317 |
|
| 2013 |
Coulon A, Ferguson ML, Palangat M, de Turris V, Singer RH, Chow CC, Larson DR. Direct Measurement of Initiation, Elongation, Splicing and Termination Kinetics in Living Human Cells Biophysical Journal. 104: 372a. DOI: 10.1016/J.Bpj.2012.11.2066 |
0.7 |
|
| 2012 |
Palangat M, Larson DR. Complexity of RNA polymerase II elongation dynamics. Biochimica Et Biophysica Acta. 1819: 667-72. PMID 22480952 DOI: 10.1016/J.Bbagrm.2012.02.024 |
0.4 |
|
| 2012 |
Trcek T, Chao JA, Larson DR, Park HY, Zenklusen D, Shenoy SM, Singer RH. Single-mRNA counting using fluorescent in situ hybridization in budding yeast. Nature Protocols. 7: 408-19. PMID 22301778 DOI: 10.1038/Nprot.2011.451 |
0.574 |
|
| 2012 |
Singer RH, Lionnet T, Yoon Park H, Wu B, Trcek T, Hocine S, Larson D. Following Single mRNAs from Birth to Death in Living Cells Biophysical Journal. 102: 609a-610a. DOI: 10.1016/J.Bpj.2011.11.3323 |
0.464 |
|
| 2011 |
Trcek T, Larson DR, Moldón A, Query CC, Singer RH. Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast. Cell. 147: 1484-97. PMID 22196726 DOI: 10.1016/J.Cell.2011.11.051 |
0.387 |
|
| 2011 |
Larson DR. What do expression dynamics tell us about the mechanism of transcription? Current Opinion in Genetics & Development. 21: 591-9. PMID 21862317 DOI: 10.1016/J.Gde.2011.07.010 |
0.418 |
|
| 2011 |
Larson DR, Zenklusen D, Wu B, Chao JA, Singer RH. Real-time observation of transcription initiation and elongation on an endogenous yeast gene. Science (New York, N.Y.). 332: 475-8. PMID 21512033 DOI: 10.1126/Science.1202142 |
0.469 |
|
| 2011 |
Larson DR, Fritzsch C, Sun L, Meng X, Condeelis J, Lawrence D, Singer R. Measurement and Modulation of Nuclear Receptor-Mediated Transcription in Single Cells Using Light Biophysical Journal. 100: 64a. DOI: 10.1016/J.Bpj.2010.12.548 |
0.382 |
|
| 2010 |
Lionnet T, Wu B, Grünwald D, Singer RH, Larson DR. Nuclear physics: quantitative single-cell approaches to nuclear organization and gene expression. Cold Spring Harbor Symposia On Quantitative Biology. 75: 113-26. PMID 21502409 DOI: 10.1101/Sqb.2010.75.057 |
0.362 |
|
| 2009 |
Larson DR, Singer RH, Zenklusen D. A single molecule view of gene expression. Trends in Cell Biology. 19: 630-7. PMID 19819144 DOI: 10.1016/J.Tcb.2009.08.008 |
0.368 |
|
| 2009 |
Darzacq X, Yao J, Larson DR, Causse SZ, Bosanac L, de Turris V, Ruda VM, Lionnet T, Zenklusen D, Guglielmi B, Tjian R, Singer RH. Imaging transcription in living cells. Annual Review of Biophysics. 38: 173-96. PMID 19416065 DOI: 10.1146/Annurev.Biophys.050708.133728 |
0.529 |
|
| 2008 |
Zenklusen D, Larson DR, Singer RH. Single-RNA counting reveals alternative modes of gene expression in yeast. Nature Structural & Molecular Biology. 15: 1263-71. PMID 19011635 DOI: 10.1038/Nsmb.1514 |
0.41 |
|
| 2008 |
Larson DR, Ow H, Vishwasrao HD, Heikal AA, Wiesner U, Webb WW. Silica nanoparticle architecture determines radiative properties of encapsulated fluorophores Chemistry of Materials. 20: 2677-2684. DOI: 10.1021/Cm7026866 |
0.717 |
|
| 2007 |
Larson D, Gosse J, Holowka D, Baird B, Webb W. Temporally Resolved Interactions Between IgE Receptors and Lyn Kinase on Living Cells Measured by 2-photon Fluorescence Correlation Spectroscopy Microscopy and Microanalysis. 13. DOI: 10.1017/S1431927607075228 |
0.518 |
|
| 2005 |
Larson DR, Gosse JA, Holowka DA, Baird BA, Webb WW. Temporally resolved interactions between antigen-stimulated IgE receptors and Lyn kinase on living cells. The Journal of Cell Biology. 171: 527-36. PMID 16275755 DOI: 10.1083/Jcb.200503110 |
0.502 |
|
| 2005 |
Larson DR, Johnson MC, Webb WW, Vogt VM. Visualization of retrovirus budding with correlated light and electron microscopy. Proceedings of the National Academy of Sciences of the United States of America. 102: 15453-8. PMID 16230638 DOI: 10.1073/Pnas.0504812102 |
0.528 |
|
| 2005 |
Yao J, Larson DR, Vishwasrao HD, Zipfel WR, Webb WW. Blinking and nonradiant dark fraction of water-soluble quantum dots in aqueous solution. Proceedings of the National Academy of Sciences of the United States of America. 102: 14284-9. PMID 16169907 DOI: 10.1073/Pnas.0506523102 |
0.736 |
|
| 2005 |
Ow H, Larson DR, Srivastava M, Baird BA, Webb WW, Wiesner U. Bright and stable core-shell fluorescent silica nanoparticles. Nano Letters. 5: 113-7. PMID 15792423 DOI: 10.1021/Nl0482478 |
0.494 |
|
| 2005 |
Yao J, Larson DR, Zipfel WR, Webb WW. Dark fraction and blinking of water-soluble quantum dots in solution Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5705: 148-151. DOI: 10.1117/12.606131 |
0.703 |
|
| 2003 |
Larson DR, Ma YM, Vogt VM, Webb WW. Direct measurement of Gag-Gag interaction during retrovirus assembly with FRET and fluorescence correlation spectroscopy. The Journal of Cell Biology. 162: 1233-44. PMID 14517204 DOI: 10.1083/Jcb.200303200 |
0.508 |
|
| 2003 |
Larson DR, Zipfel WR, Williams RM, Clark SW, Bruchez MP, Wise FW, Webb WW. Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science (New York, N.Y.). 300: 1434-6. PMID 12775841 DOI: 10.1126/Science.1083780 |
0.674 |
|
| 2003 |
Larson DR, Ma YM, Vogt VM, Webb WW. Direct observation of retrovirus assembly with FRET, fluorescence correlation spectroscopy, and single particle tracking Microscopy and Microanalysis. 9: 1146-1147. DOI: 10.1017/S143192760344573X |
0.525 |
|
| 2002 |
Thompson RE, Larson DR, Webb WW. Precise nanometer localization analysis for individual fluorescent probes. Biophysical Journal. 82: 2775-83. PMID 11964263 DOI: 10.1016/S0006-3495(02)75618-X |
0.645 |
|
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