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George Perry, AA, BA, PhD, HonD - Related publications

Biology University of Texas at San Antonio, San Antonio, TX, United States 
Alzheimer's disease, oxidative stress, cytoskeleton
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Martinez B, Peplow PV. Amelioration of Alzheimer's disease pathology and cognitive deficits by immunomodulatory agents in animal models of Alzheimer's disease. Neural Regeneration Research. 14: 1158-1176. PMID 30804241 DOI: 10.4103/1673-5374.251192   
2019 Foveau B, Correia AS, Hébert SS, Rainone S, Potvin O, Kergoat MJ, Belleville S, Duchesne S, LeBlanc AC, . Stem Cell-Derived Neurons as Cellular Models of Sporadic Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30689579 DOI: 10.3233/JAD-180833   
2019 Islam BU, Jabir NR, Tabrez S. The role of mitochondrial defects and oxidative stress in Alzheimer's disease. Journal of Drug Targeting. 1-32. PMID 30775938 DOI: 10.1080/1061186X.2019.1584808   
2019 Illes P, Rubini P, Huang L, Tang Y. The P2X7 receptor: a new therapeutic target in Alzheimer's disease. Expert Opinion On Therapeutic Targets. PMID 30691318 DOI: 10.1080/14728222.2019.1575811   
2019 Bazzari FH, Abdallah DM, El-Abhar HS. Pharmacological Interventions to Attenuate Alzheimer's Disease Progression: The Story So Far. Current Alzheimer Research. PMID 30827243 DOI: 10.2174/1567205016666190301111120   
2019 Dong Y, Li X, Cheng J, Hou L. Drug Development for Alzheimer's Disease: Microglia Induced Neuroinflammation as a Target? International Journal of Molecular Sciences. 20. PMID 30696107 DOI: 10.3390/ijms20030558   
2019 Mullane K, Williams M. Preclinical Models of Alzheimer's Disease: Relevance and Translational Validity. Current Protocols in Pharmacology. e57. PMID 30802363 DOI: 10.1002/cpph.57   
2019 Perez Ortiz JM, Swerdlow RH. Mitochondrial dysfunction in Alzheimer's disease: Role in pathogenesis and novel therapeutic opportunities. British Journal of Pharmacology. PMID 30675901 DOI: 10.1111/bph.14585   
2019 Saha P, Sen N. Tauopathy: A common mechanism for neurodegeneration and Brain Aging. Mechanisms of Ageing and Development. PMID 30668956 DOI: 10.1016/j.mad.2019.01.007   
2019 Yamazaki Y, Shinohara M, Shinohara M, Yamazaki A, Murray ME, Liesinger AM, Heckman MG, Lesser ER, Parisi JE, Petersen RC, Dickson DW, Kanekiyo T, Bu G. Selective loss of cortical endothelial tight junction proteins during Alzheimer's disease progression. Brain : a Journal of Neurology. PMID 30770921 DOI: 10.1093/brain/awz011   
2019 Lee HE, Lim D, Lee JY, Lim SM, Pae AN. Development of tau-directed small molecule modulators for Alzheimer's disease: a recent patent review (2014-2018). Pharmaceutical Patent Analyst. PMID 30870110 DOI: 10.4155/ppa-2019-0003   
2019 Alexander J, Ströbel T, Georgitsi M, Hönigschnabl S, Reiner A, Fischer P, Tsifintaris M, Paschou P, Kovacs GG. Neuropathology-driven Whole-genome Sequencing Study Points to Novel Candidate Genes for Healthy Brain Aging. Alzheimer Disease and Associated Disorders. PMID 30681437 DOI: 10.1097/WAD.0000000000000294   
2019 Lott IT, Head E. Dementia in Down syndrome: unique insights for Alzheimer disease research. Nature Reviews. Neurology. PMID 30733618 DOI: 10.1038/s41582-018-0132-6   
2019 Santos JRF, Bauer C, Schuchhardt J, Wedekind D, Waniek K, Lachmann I, Wiltfang J, Vogelgsang J. Validation of a prototype tau Thr231 phosphorylation CSF ELISA as a potential biomarker for Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 30767082 DOI: 10.1007/s00702-019-01982-5   
2019 Guzmán-Martínez L, Tapia JP, Farías GA, González A, Estrella M, Maccioni RB. The Alz-tau Biomarker for Alzheimer's Disease: Study in a Caucasian Population. Journal of Alzheimer's Disease : Jad. PMID 30775977 DOI: 10.3233/JAD-180637   
2019 Dhiman K, Blennow K, Zetterberg H, Martins RN, Gupta VB. Cerebrospinal fluid biomarkers for understanding multiple aspects of Alzheimer's disease pathogenesis. Cellular and Molecular Life Sciences : Cmls. PMID 30770953 DOI: 10.1007/s00018-019-03040-5   
2019 Guest FL. Early Detection and Treatment of Patients with Alzheimer's Disease: Future Perspectives. Advances in Experimental Medicine and Biology. 1118: 295-317. PMID 30747429 DOI: 10.1007/978-3-030-05542-4_15   
2019 Poirier Y, Grimm A, Schmitt K, Eckert A. Link between the unfolded protein response and dysregulation of mitochondrial bioenergetics in Alzheimer's disease. Cellular and Molecular Life Sciences : Cmls. PMID 30683981 DOI: 10.1007/s00018-019-03009-4   
2019 Takatori S, Wang W, Iguchi A, Tomita T. Genetic Risk Factors for Alzheimer Disease: Emerging Roles of Microglia in Disease Pathomechanisms. Advances in Experimental Medicine and Biology. 1118: 83-116. PMID 30747419 DOI: 10.1007/978-3-030-05542-4_5   
2019 Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X, Rocktäschel P, Croteau DL, Akbari M, Greig NH, Fladby T, et al. Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease. Nature Neuroscience. PMID 30742114 DOI: 10.1038/s41593-018-0332-9   
2019 Franzmeier N, Rubinski A, Neitzel J, Kim Y, Damm A, Na DL, Kim HJ, Lyoo CH, Cho H, Finsterwalder S, Duering M, Seo SW, Ewers M, . Functional connectivity associated with tau levels in ageing, Alzheimer's, and small vessel disease. Brain : a Journal of Neurology. PMID 30770704 DOI: 10.1093/brain/awz026   
2019 Xu J, Patassini S, Rustogi N, Riba-Garcia I, Hale BD, Phillips AM, Waldvogel H, Haines R, Bradbury P, Stevens A, Faull RLM, Dowsey AW, Cooper GJS, Unwin RD. Regional protein expression in human Alzheimer's brain correlates with disease severity. Communications Biology. 2: 43. PMID 30729181 DOI: 10.1038/s42003-018-0254-9   
2019 Mudò G, Frinchi M, Nuzzo D, Scaduto P, Plescia F, Massenti MF, Di Carlo M, Cannizzaro C, Cassata G, Cicero L, Ruscica M, Belluardo N, Grimaldi LM. Anti-inflammatory and cognitive effects of interferon-β1a (IFNβ1a) in a rat model of Alzheimer's disease. Journal of Neuroinflammation. 16: 44. PMID 30777084 DOI: 10.1186/s12974-019-1417-4   
2019 Chen CLH, Sharma PR, Tan BY, Low C, Venketasubramanian N. The lzheimer's disease rapy with uroaid () study protocol: Assessing the safety and efficacy of Neuroaid II (MLC901) in patients with mild-to-moderate Alzheimer's disease stable on cholinesterase inhibitors or memantine-A randomized, double-blind, placebo-controlled trial. Alzheimer's & Dementia (New York, N. Y.). 5: 38-45. PMID 30723778 DOI: 10.1016/j.trci.2018.12.001   
2019 McKetney J, Runde R, Hebert AS, Salamat S, Roy S, Coon JJ. Proteomic atlas of the human brain in Alzheimer's disease. Journal of Proteome Research. PMID 30735395 DOI: 10.1021/acs.jproteome.9b00004   
2019 Espay AJ, Vizcarra JA, Marsili L, Lang AE, Simon DK, Merola A, Josephs KA, Fasano A, Morgante F, Savica R, Greenamyre JT, Cambi F, Yamasaki TR, Tanner CM, Gan-Or Z, et al. Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. Neurology. 92: 329-337. PMID 30745444 DOI: 10.1212/WNL.0000000000006926   
2019 Abid NB, Naseer MI, Kim MO. Comparative Gene-Expression Analysis of Alzheimer's Disease Progression with Aging in Transgenic Mouse Model. International Journal of Molecular Sciences. 20. PMID 30862043 DOI: 10.3390/ijms20051219   
2019 Kaushal A, Wani WY, Bal A, Gill KD, Kaur J. Okadaic Acid and Hypoxia Induced Dementia Model of Alzheimer's Type in Rats. Neurotoxicity Research. PMID 30729451 DOI: 10.1007/s12640-019-0005-9   
2019 Butterfield DA, Halliwell B. Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease. Nature Reviews. Neuroscience. 20: 148-160. PMID 30737462 DOI: 10.1038/s41583-019-0132-6   
2019 Gordon BA, Blazey TM, Christensen J, Dincer A, Flores S, Keefe S, Chen C, Su Y, McDade EM, Wang G, Li Y, Hassenstab J, Aschenbrenner A, Hornbeck R, Jack CR, et al. Tau PET in autosomal dominant Alzheimer's disease: relationship with cognition, dementia and other biomarkers. Brain : a Journal of Neurology. PMID 30753379 DOI: 10.1093/brain/awz019   
2019 Wallace LMK, Theou O, Godin J, Andrew MK, Bennett DA, Rockwood K. Investigation of frailty as a moderator of the relationship between neuropathology and dementia in Alzheimer's disease: a cross-sectional analysis of data from the Rush Memory and Aging Project. The Lancet. Neurology. 18: 177-184. PMID 30663607 DOI: 10.1016/S1474-4422(18)30371-5   
2019 Castellani RJ, Plascencia-Villa G, Perry G. The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 30760863 DOI: 10.1038/s41374-019-0231-z   
2019 Jicha GA, Nelson PT. Hippocampal Sclerosis, Argyrophilic Grain Disease, and Primary Age-Related Tauopathy. Continuum (Minneapolis, Minn.). 25: 208-233. PMID 30707194 DOI: 10.1212/CON.0000000000000697   
2019 Sim KY, Park SH, Choi KY, Park JE, Lee JS, Kim BC, Gwak J, Song WK, Lee KH, Park SG. High-throughput epitope profiling of antibodies in the plasma of Alzheimer's disease patients using random peptide microarrays. Scientific Reports. 9: 4587. PMID 30872784 DOI: 10.1038/s41598-019-40976-x   
2019 Fuller JT, Cronin-Golomb A, Gatchel JR, Norton DJ, Guzmán-Vélez E, Jacobs HIL, Hanseeuw B, Pardilla-Delgado E, Artola A, Baena A, Bocanegra Y, Kosik KS, Chen K, Tariot PN, Johnson K, et al. Biological and Cognitive Markers of Presenilin1 E280A Autosomal Dominant Alzheimer's Disease: A Comprehensive Review of the Colombian Kindred. The Journal of Prevention of Alzheimer's Disease. 6: 112-120. PMID 30756118 DOI: 10.14283/jpad.2019.6   
2019 Arif N, Subhani A, Hussain W, Rasool N. In silico Inhibition of BACE-1 by Selective Phytochemicals as Novel Potential Inhibitors: Molecular Docking and DFT Studies. Current Drug Discovery Technologies. PMID 30767744 DOI: 10.2174/1570163816666190214161825   
2019 Nday CN, Eleftheriadou D, Jackson G. Magnetic chrysin silica nanomaterials behavior in an amyloidogenic environment. Hellenic Journal of Nuclear Medicine. 22: 42-50. PMID 30877722   
2019 Jha NK, Jha SK, Kar R, Nand P, Swati K, Goswami VK. Nuclear Factor-Kappa β as a therapeutic target for Alzheimer's disease. Journal of Neurochemistry. PMID 30802950 DOI: 10.1111/jnc.14687   
2019 Jessen F. [Early detection of Alzheimer's disease and approaches for prevention]. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. PMID 30680409 DOI: 10.1007/s00103-019-02877-2   
2019 Adav SS, Park JE, Sze SK. Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer's disease. Molecular Brain. 12: 8. PMID 30691479 DOI: 10.1186/s13041-019-0430-y   
2019 Reynolds DS. A short perspective on the long road to effective treatments for Alzheimer's disease. British Journal of Pharmacology. PMID 30657599 DOI: 10.1111/bph.14581   
2019 Tavana JP, Rosene M, Jensen NO, Ridge PG, Kauwe JS, Karch CM. RAB10: an Alzheimer's disease resilience locus and potential drug target. Clinical Interventions in Aging. 14: 73-79. PMID 30643396 DOI: 10.2147/CIA.S159148   
2019 Mitra S, Behbahani H, Eriksdotter M. Innovative Therapy for Alzheimer's Disease-With Focus on Biodelivery of NGF. Frontiers in Neuroscience. 13: 38. PMID 30804738 DOI: 10.3389/fnins.2019.00038   
2019 Su C, Zhao K, Xia H, Xu Y. Peripheral inflammatory biomarkers in Alzheimer's disease and mild cognitive impairment: a systematic review and meta-analysis. Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society. PMID 30790387 DOI: 10.1111/psyg.12403   
2019 Mullane K, Williams M. The de-Alzheimerization of age-related dementias: implications for drug targets and approaches to effective therapeutics. Current Opinion in Pharmacology. PMID 30795894 DOI: 10.1016/j.coph.2019.01.004   
2019 Zeng Q, Siu W, Li L, Jin Y, Liang S, Cao M, Ma M, Wu Z. Autophagy in Alzheimer's disease and promising modulatory effects of herbal medicine. Experimental Gerontology. PMID 30710681 DOI: 10.1016/j.exger.2019.01.027   
2019 Hara Y, McKeehan N, Fillit HM. Translating the biology of aging into novel therapeutics for Alzheimer disease. Neurology. 92: 84-93. PMID 30530798 DOI: 10.1212/WNL.0000000000006745   
2019 Chen YC, Chiu YJ, Lin CH, Hsu WC, Wu JL, Huang CH, Lin CW, Yao CF, Huang HJ, Chen CM, Wu YR, Chang KH, Lee-Chen GJ, Mei Hsieh-Li H. Indole Compound NC009-1 Augments APOE and TRKA in Alzheimer's Disease Cell and Mouse Models for Neuroprotection and Cognitive Improvement. Journal of Alzheimer's Disease : Jad. PMID 30689566 DOI: 10.3233/JAD-180643   
2019 Patel TK, Habimana-Griffin L, Gao X, Xu B, Achilefu S, Alitalo K, McKee CA, Sheehan PW, Musiek ES, Xiong C, Coble D, Holtzman DM. Dural lymphatics regulate clearance of extracellular tau from the CNS. Molecular Neurodegeneration. 14: 11. PMID 30813965 DOI: 10.1186/s13024-019-0312-x   
2019 Whitwell JL, Martin P, Graff-Radford J, Machulda MM, Senjem ML, Schwarz CG, Weigand SD, Spychalla AJ, Drubach DA, Jack CR, Lowe VJ, Josephs KA. The role of age on tau PET uptake and gray matter atrophy in atypical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30853465 DOI: 10.1016/j.jalz.2018.12.016