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William (Bill) R. Brinkley, PhD, Iowa State University - Related publications

Baylor College of Medicine, Houston, TX 
mitotic apparatus
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Liu QQ, Zeng XL, Guan YL, Lu JX, Tu K, Liu FY. Verticillin A inhibits colon cancer cell migration and invasion by targeting c-Met. Journal of Zhejiang University. Science. B. 21: 779-795. PMID 33043644 DOI: 10.1631/jzus.B2000190   
2020 Kim MJ, Kang YJ, Sung B, Jang JY, Ahn YR, Oh HJ, Choi H, Choi I, Im E, Moon HR, Chung HY, Kim ND. Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells. Biomolecules & Therapeutics. PMID 33073770 DOI: 10.4062/biomolther.2020.153   
2020 Makino T, Mizawa M, Yoshihisa Y, Yamamoto S, Tabuchi Y, Miyai M, Hibino T, Sasahara M, Shimizu T. Trichohyalin-like 1 protein plays a crucial role in proliferation and anti-apoptosis of normal human keratinocytes and squamous cell carcinoma cells. Cell Death Discovery. 6: 109. PMID 33133644 DOI: 10.1038/s41420-020-00344-5   
2020 Liang Y, Zhang T, Ren L, Jing S, Li Z, Zuo P, Li T, Wang Y, Zhang J, Wei Z. Cucurbitacin IIb induces apoptosis and cell cycle arrest through regulating EGFR/MAPK pathway. Environmental Toxicology and Pharmacology. 103542. PMID 33161110 DOI: 10.1016/j.etap.2020.103542   
2020 Kim PR, Zhang S, Rahmat MB, Koh CG. Partners in crime: POPX2 phosphatase and its interacting proteins in cancer. Cell Death & Disease. 11: 840. PMID 33037179 DOI: 10.1038/s41419-020-03061-0   
2020 Song J, Bai J, Wang S, Liu L, Zhao Z. [Effects of Quercetin on Autophagy and Phosphatidylinositol 3-kinase/Protein Kinase B/Mammalian Target of Rapamycin Signaling Pathway in Human Prostate Cancer PC-3 Cells]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 42: 578-584. PMID 33131510 DOI: 10.3881/j.issn.1000-503X.12361   
2020 Kumar S, Singh SK, Rana B, Rana A. The regulatory function of mixed lineage kinase 3 in tumor and host immunity. Pharmacology & Therapeutics. 107704. PMID 33045253 DOI: 10.1016/j.pharmthera.2020.107704   
2020 Felgueiras J, Jerónimo C, Fardilha M. Protein phosphatase 1 in tumorigenesis: is it worth a closer look? Biochimica Et Biophysica Acta. Reviews On Cancer. 1874: 188433. PMID 32956763 DOI: 10.1016/j.bbcan.2020.188433   
2020 Iannuzzi CA, Indovina P, Forte IM, Di Somma S, Malfitano AM, Bruno M, Portella G, Pentimalli F, Giordano A. Pharmacological Inhibition of WEE1 Potentiates the Antitumoral Effect of the Oncolytic Virus in Malignant Mesothelioma Cell Lines. International Journal of Molecular Sciences. 21. PMID 33020398 DOI: 10.3390/ijms21197333   
2020 Moustafa-Kamal M, Kucharski TJ, El-Assaad W, Abbas YM, Gandin V, Nagar B, Pelletier J, Topisirovic I, Teodoro JG. The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest. Cell Reports. 33: 108230. PMID 33027666 DOI: 10.1016/j.celrep.2020.108230   
2020 Cho JH, Kim K, Kim SA, Park S, Park BO, Kim JH, Kim SY, Kwon MJ, Han MH, Lee SB, Park BC, Park SG, Kim JH, Kim S. Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathways. Cell Death and Differentiation. PMID 33110214 DOI: 10.1038/s41418-020-00649-z   
2020 Jeong H, Park S, Kim SY, Cho SH, Jeong MS, Kim SR, Seo JB, Kim SH, Kim KN. 1-Cinnamoyltrichilinin from Causes Apoptosis through the p38 MAPK Pathway in HL-60 Human Leukemia Cells. International Journal of Molecular Sciences. 21. PMID 33053881 DOI: 10.3390/ijms21207506   
2020 Dai C, Shen L, Jin W, Lv B, Liu P, Wang X, Yin Y, Fu Y, Liang L, Ma Z, Zhang X, Wang Y, Xu D, Chen Z. Physapubescin B enhances the sensitivity of gastric cancer cells to trametinib by inhibiting the STAT3 signaling pathway. Toxicology and Applied Pharmacology. 115273. PMID 33035574 DOI: 10.1016/j.taap.2020.115273   
2020 Tian Y, Zhao L. Metformin induces apoptosis of melanoma B16 cells via PI3K/Akt/mTOR signaling pathways. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 25: 2066-2070. PMID 33099954   
2020 Elie J, Feizbakhsh O, Desban N, Josselin B, Baratte B, Bescond A, Duez J, Fant X, Bach S, Marie D, Place M, Ben Salah S, Chartier A, Berteina-Raboin S, Chaikuad A, et al. Design of new disubstituted imidazo[1,2-]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 1840-1853. PMID 33040634 DOI: 10.1080/14756366.2020.1825408   
2020 Jena S, Damayanti NP, Tan J, Pratt ED, Irudayaraj JMK, Parker LL. Multiplexable fluorescence lifetime imaging (FLIM) probes for Abl and Src-family kinases. Chemical Communications (Cambridge, England). PMID 33035286 DOI: 10.1039/d0cc05030j   
2020 Yoshida A, Choi J, Jin HR, Li Y, Bajpai S, Qie S, Diehl JA. Fbxl8 suppresses lymphoma growth and hematopoietic transformation through degradation of cyclin D3. Oncogene. PMID 33122824 DOI: 10.1038/s41388-020-01532-4   
2020 Im JY, Kim DM, Park H, Kang MJ, Kim DY, Chang KY, Kim BK, Won M. VGLL1 phosphorylation and activation promotes gastric cancer malignancy via TGF-β/ERK/RSK2 signaling. Biochimica Et Biophysica Acta. Molecular Cell Research. 118892. PMID 33069758 DOI: 10.1016/j.bbamcr.2020.118892   
2020 Xu W, Wang Y. Post-translational Modifications of Serine/Threonine and Histidine Kinases and Their Roles in Signal Transductions in Synechocystis Sp. PCC 6803. Applied Biochemistry and Biotechnology. PMID 33159456 DOI: 10.1007/s12010-020-03435-2   
2020 Martinez R, Huang W, Samadani R, Mackowiak B, Centola G, Chen L, Conlon IL, Hom K, Kane MA, Fletcher S, Shapiro P. Mechanistic analysis of an ERK2-interacting compound that inhibits mutant-BRAF expressing melanoma cells by inducing oxidative stress. The Journal of Pharmacology and Experimental Therapeutics. PMID 33109619 DOI: 10.1124/jpet.120.000266   
2020 Asih PR, Prikas E, Stefanoska K, Tan ARP, Ahel HI, Ittner A. Functions of p38 MAP Kinases in the Central Nervous System. Frontiers in Molecular Neuroscience. 13: 570586. PMID 33013322 DOI: 10.3389/fnmol.2020.570586   
2020 Sharifinejad N, Azizi G, Behniafard N, Zaki-Dizaji M, Jamee M, Yazdani R, Abolhassani H, Aghamohammadi A. Protein Kinase C-Delta Defect in Autoimmune Lymphoproliferative Syndrome-Like Disease: First Case from the National Iranian Registry and Review of the Literature. Immunological Investigations. 1-12. PMID 33047643 DOI: 10.1080/08820139.2020.1829638   
2020 Sebastião MM, Ho RS, de Carvalho JPV, Nussbaum M. Diagnostic Accuracy of Next Generation Sequencing Panel using Circulating Tumor DNA in Patients with Advanced Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis. Journal of Health Economics and Outcomes Research. 7: 158-163. PMID 33043062 DOI: 10.36469/jheor.2020.17088   
2020 Sepúlveda-Sánchez JM, Gil-Gil M, Alonso-García M, Vaz Salgado MÁ, Vicente E, Mesía Barroso C, Rodríguez Sánchez Á, Durán G, De Las Peñas R, Muñoz-Langa J, Velasco G, Hernández-Laín A, Hilario A, Navarro Martín M, Benavides M, et al. Phase II Trial of Palbociclib in Recurrent Retinoblastoma-Positive Anaplastic Oligodendroglioma: A Study from the Spanish Group for Research in Neuro-Oncology (GEINO). Targeted Oncology. 15: 613-622. PMID 33025213 DOI: 10.1007/s11523-020-00754-6   
2020 Soamalala J, Diot S, Pellerano M, Blanquart C, Galibert M, Jullian M, Puget K, Morris MC. Fluorescent peptide biosensor for probing CDK6 activity in lung cancer cell extracts. Chembiochem : a European Journal of Chemical Biology. PMID 33112024 DOI: 10.1002/cbic.202000677   
2020 Sun Z, Song Y, Chen D, Zang Y, Zhang Q, Yi Y, Qu G. Genome-Wide Identification, Classification, Characterization, and Expression Analysis of the Wall-Associated Kinase Family during Fruit Development and under Wound Stress in Tomato ( L.). Genes. 11. PMID 33053790 DOI: 10.3390/genes11101186   
2020 Velázquez D, Albacar M, Zhang C, Calafí C, López-Malo M, Torres-Torronteras J, Martí R, Kovalchuk SI, Pinson B, Jensen ON, Daignan-Fornier B, Casamayor A, Ariño J. Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets. Scientific Reports. 10: 15613. PMID 32973189 DOI: 10.1038/s41598-020-72391-y   
2020 Velázquez D, Albacar M, Zhang C, Calafí C, López-Malo M, Torres-Torronteras J, Martí R, Kovalchuk SI, Pinson B, Jensen ON, Daignan-Fornier B, Casamayor A, Ariño J. Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets. Scientific Reports. 10: 15613. PMID 32973189 DOI: 10.1038/s41598-020-72391-y   
2020 Alme EB, Toczyski DP. Redundant targeting of Isr1 by two CDKs in mitotic cells. Current Genetics. PMID 33063175 DOI: 10.1007/s00294-020-01110-x   
2020 Lu Y, Sun H. Progress in the Development of Small Molecular Inhibitors of Focal Adhesion Kinase (FAK). Journal of Medicinal Chemistry. PMID 33058670 DOI: 10.1021/acs.jmedchem.0c01248   
2020 Chen L, Wang X, Cheng H, Zhang W, Liu Y, Zeng W, Yu L, Huang C, Liu G. Cyclin Y binds and activates CDK4 to promote the G1/S phase transition in hepatocellular carcinoma cells via Rb signaling. Biochemical and Biophysical Research Communications. PMID 33039146 DOI: 10.1016/j.bbrc.2020.09.127   
2020 Baffi TR, Katsenelson KC, Newton AC. PHLPPing the Script: Emerging Roles of PHLPP Phosphatases in Cell Signaling. Annual Review of Pharmacology and Toxicology. PMID 32997603 DOI: 10.1146/annurev-pharmtox-031820-122108   
2020 Abdel Aziz MH, Fan Y, Liu L, Moasser M, Fu H, Jura N, Arkin MR. Expression and Purification of Active Human Kinases Using Pichia pastoris as A General-Purpose Host. Protein Expression and Purification. 105780. PMID 33115654 DOI: 10.1016/j.pep.2020.105780   
2020 Das D, Chen SY, Arur S. ERK phosphorylates chromosomal axis component HORMA domain protein HTP-1 to regulate oocyte numbers. Science Advances. 6. PMID 33127680 DOI: 10.1126/sciadv.abc5580   
2020 Li Y, Shi J, Yang J, Ge S, Zhang J, Jia R, Fan X. Uveal melanoma: progress in molecular biology and therapeutics. Therapeutic Advances in Medical Oncology. 12: 1758835920965852. PMID 33149769 DOI: 10.1177/1758835920965852   
2020 Fang CY, Lai TC, Hsiao M, Chang YC. The Diverse Roles of TAO Kinases in Health and Diseases. International Journal of Molecular Sciences. 21. PMID 33050415 DOI: 10.3390/ijms21207463   
2020 Wang W, Guo X, Dan H. α2A-Adrenergic Receptor Inhibits the Progression of Cervical Cancer Through Blocking PI3K/AKT/mTOR Pathway. Oncotargets and Therapy. 13: 10535-10546. PMID 33116632 DOI: 10.2147/OTT.S264409   
2020 Murugesan S, Murugesan J, Palaniappan S, Palaniappan S, Murugan T, Siddiqui SS, Loganathan S. Tyrosine Kinase Inhibitors (TKIs) in Lung Cancer Treatment: a Comprehensive Analysis. Current Cancer Drug Targets. PMID 33038912 DOI: 10.2174/1568009620666201009130008   
2020 Choi H, Roh J. LH-induced Transcriptional Regulation of Expression in Granulosa Cells Occurs via the cAMP/PKA Pathway and Requires a Putative Sp1 Binding Site. International Journal of Molecular Sciences. 21. PMID 33036290 DOI: 10.3390/ijms21197385   
2020 Qiao G, Bi K, Liu J, Cao S, Liu M, Pešić M, Lin X. Protein kinases as targets for developing anticancer agents from marine organisms. Biochimica Et Biophysica Acta. General Subjects. 129759. PMID 33038451 DOI: 10.1016/j.bbagen.2020.129759   
2020 Roberto J, Sykes CE, Vacratsis PO. Characterization of Phosphopeptide Positional Isomers on the Transcriptional Co-activator TAZ. Biochemistry. PMID 33086783 DOI: 10.1021/acs.biochem.0c00521   
2020 Huang L, Jiang S, Shi Y. Tyrosine kinase inhibitors for solid tumors in the past 20 years (2001-2020). Journal of Hematology & Oncology. 13: 143. PMID 33109256 DOI: 10.1186/s13045-020-00977-0   
2020 Park CS, Lacorazza HD. DYRK2 controls a key regulatory network in chronic myeloid leukemia stem cells. Experimental & Molecular Medicine. PMID 33067577 DOI: 10.1038/s12276-020-00515-5   
2020 Stein V, Blank-Landeshammer B, Müntjes K, Märker R, Teichert I, Feldbrügge M, Sickmann A, Kück U. The STRIPAK signaling complex regulates dephosphorylation of GUL1, an RNA-binding protein that shuttles on endosomes. Plos Genetics. 16: e1008819. PMID 32997654 DOI: 10.1371/journal.pgen.1008819   
2020 Kumar S, Agrawal S, Maity S, AlRaawi Z, Al-Ameer M. Targeting Drugs Against Fibroblast Growth Factor(s)-Induced Cell Signaling. Current Drug Targets. PMID 33045958 DOI: 10.2174/1389450121999201012201926   
2020 Chen H, Libring S, Ruddraraju KV, Miao J, Solorio L, Zhang ZY, Wendt MK. SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer. Oncogene. PMID 33033382 DOI: 10.1038/s41388-020-01488-5   
2020 Yoshida A, Yamamoto K, Ishida T, Omura T, Itoh T, Nishigori C, Sakane T, Yano I. Sunitinib decreases the expression of KRT6A and SERPINB1 in 3D human epidermal models. Experimental Dermatology. PMID 33135264 DOI: 10.1111/exd.14230   
2020 Liu CZ, Guo WP, Peng JB, Chen G, Lin P, Huang XL, Liu XF, Yang H, He Y, Pang YY, Ma W. Clinical significance of CCNE2 protein and mRNA expression in thyroid cancer tissues. Advances in Medical Sciences. 65: 442-456. PMID 33059229 DOI: 10.1016/j.advms.2020.09.001   
2020 Singh S, Smith MJ. RAS GTPase signalling to alternative effector pathways. Biochemical Society Transactions. 48: 2241-2252. PMID 33125484 DOI: 10.1042/BST20200506   
2020 Zhang H, Lu S, Xu R, Tang Y, Liu J, Li C, Wei J, Yao R, Zhao X, Wei Q, Ma B. Mechanisms of estradiol-induced EGF-like factor expression and oocyte maturation via G protein-coupled estrogen receptor. Endocrinology. PMID 33068422 DOI: 10.1210/endocr/bqaa190