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Paula Isabel Moreira, PhD, University of Coimbra - Publications

Affiliations: 
Center for Neuroscience and Cell Biology University of Coimbra, Coimbra, Coimbra, Portugal 
Area:
Alzheimer's disease, oxidative stress
Website:
http://www.cnbc.pt/research/areaA34_2.asp
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Year Citation  Score
2023 Sousa T, Moreira PI, Cardoso S. Current Advances in Mitochondrial Targeted Interventions in Alzheimer's Disease. Biomedicines. 11. PMID 37760774 DOI: 10.3390/biomedicines11092331  0.393
2023 Carvalho C, Moreira PI. Metabolic defects shared by Alzheimer's disease and diabetes: A focus on mitochondria. Current Opinion in Neurobiology. 79: 102694. PMID 36842275 DOI: 10.1016/j.conb.2023.102694  0.367
2022 Carvalho C, Correia SC, Seiça R, Moreira PI. WWOX inhibition by Zfra1-31 restores mitochondrial homeostasis and viability of neuronal cells exposed to high glucose. Cellular and Molecular Life Sciences : Cmls. 79: 487. PMID 35984507 DOI: 10.1007/s00018-022-04508-7  0.689
2022 Correia SC, Alves MG, Oliveira PF, Casadesus G, LaManna J, Perry G, Moreira PI. Hypoxic preconditioning averts sporadic Alzheimer's disease-like phenotype in rats: a focus on mitochondria. Antioxidants & Redox Signaling. PMID 35316086 DOI: 10.1089/ars.2019.8007  0.805
2021 Correia SC, Moreira PI. Oxygen Sensing and Signaling in Alzheimer's Disease: A Breathtaking Story! Cellular and Molecular Neurobiology. PMID 34510330 DOI: 10.1007/s10571-021-01148-6  0.687
2021 Fernandes T, Resende R, Silva DF, Marques AP, Santos AE, Cardoso SM, Domingues MR, Moreira PI, Pereira CF. Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer's Disease. Biomedicines. 9. PMID 34440085 DOI: 10.3390/biomedicines9080881  0.375
2021 Rodrigues-Neves AC, Carecho R, Correia SC, Carvalho C, Campos EJ, Baptista FI, Moreira PI, Ambrósio AF. Retina and Brain Display Early and Differential Molecular and Cellular Changes in the 3xTg-AD Mouse Model of Alzheimer's Disease. Molecular Neurobiology. PMID 33606195 DOI: 10.1007/s12035-021-02316-x  0.662
2021 Correia SC, Machado NJ, Alves MG, Oliveira PF, Moreira PI. Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33466445 DOI: 10.3390/ijms22010461  0.707
2020 Quinn PMJ, Moreira PI, Ambrósio AF, Alves CH. PINK1/PARKIN signalling in neurodegeneration and neuroinflammation. Acta Neuropathologica Communications. 8: 189. PMID 33168089 DOI: 10.1186/s40478-020-01062-w  0.388
2020 Cardoso S, Moreira PI. Antidiabetic drugs for Alzheimer's and Parkinson's diseases: Repurposing insulin, metformin, and thiazolidinediones. International Review of Neurobiology. 155: 37-64. PMID 32854858 DOI: 10.1016/bs.irn.2020.02.010  0.44
2020 Cunnane SC, Trushina E, Morland C, Prigione A, Casadesus G, Andrews ZB, Beal MF, Bergersen LH, Brinton RD, de la Monte S, Eckert A, Harvey J, Jeggo R, Jhamandas JH, Kann O, ... ... Moreira PI, et al. Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing. Nature Reviews. Drug Discovery. PMID 32709961 DOI: 10.1038/S41573-020-0072-X  0.655
2020 Duarte AI, Candeias E, Alves IN, Mena D, Silva DF, Machado NJ, Campos EJ, Santos MS, Oliveira CR, Moreira PI. Liraglutide Protects Against Brain Amyloid-β Accumulation in Female Mice with Early Alzheimer's Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation. International Journal of Molecular Sciences. 21. PMID 32143329 DOI: 10.3390/ijms21051746  0.455
2020 Resende R, Fernandes T, Pereira AC, De Pascale J, Marques AP, Oliveira P, Morais S, Santos V, Madeira N, Pereira C, Moreira PI. Mitochondria, endoplasmic reticulum and innate immune dysfunction in mood disorders: Do mitochondria-associated membranes (MAMs) play a role? Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165752. PMID 32119897 DOI: 10.1016/J.Bbadis.2020.165752  0.35
2020 Ferreira H, Martins J, Nunes A, Moreira PI, Castelo-Branco M, Ambrósio AF, Serranho P, Bernardes R. Characterization of the retinal changes of the 3×Tg-AD mouse model of Alzheimer’s disease Health Technology. 10: 875-883. DOI: 10.1007/978-3-030-31635-8_220  0.367
2019 Coimbra JR, Sobral PJ, Santos AE, Moreira PI, Salvador JA. An overview of glutaminyl cyclase inhibitors for Alzheimer's disease. Future Medicinal Chemistry. 11: 3179-3194. PMID 31838899 DOI: 10.4155/fmc-2019-0163  0.441
2019 Pinho BR, Duarte AI, Canas PM, Moreira PI, Murphy MP, Oliveira JA. The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice. Free Radical Biology & Medicine. PMID 31751762 DOI: 10.1016/j.freeradbiomed.2019.11.021  0.406
2019 Chiquita S, Campos EJ, Castelhano J, Ribeiro M, Sereno J, Moreira PI, Castelo-Branco M, Ambrósio AF. Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer's disease: a longitudinal multimodal in vivo study. Alzheimer's Research & Therapy. 11: 90. PMID 31722748 DOI: 10.1186/s13195-019-0542-8  0.412
2019 Pereira CF, Santos AE, Moreira PI, Pereira AC, Sousa FJ, Cardoso SM, Cruz MT. Is Alzheimer's disease an inflammasomopathy? Ageing Research Reviews. 100966. PMID 31577960 DOI: 10.1016/J.Arr.2019.100966  0.502
2019 Correia SC, Carvalho C, Cardoso S, Moreira PI. Post-translational modifications in brain health and disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 31102788 DOI: 10.1016/J.Bbadis.2019.05.006  0.659
2019 Carvalho C, Cardoso SM, Correia SC, Moreira PI. Tortuous Paths of Insulin Signaling and Mitochondria in Alzheimer's Disease. Advances in Experimental Medicine and Biology. 1128: 161-183. PMID 31062330 DOI: 10.1007/978-981-13-3540-2_9  0.736
2019 Chiquita S, Ribeiro M, Castelhano J, Oliveira F, Sereno J, Batista M, Abrunhosa A, Rodrigues-Neves AC, Carecho R, Baptista F, Gomes C, Moreira PI, Ambrósio AF, Castelo-Branco M. A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss. Human Molecular Genetics. PMID 30816415 DOI: 10.1093/hmg/ddz045  0.39
2019 Chiquita S, Rodrigues-Neves AC, Baptista FI, Carecho R, Moreira PI, Castelo-Branco M, Ambrósio AF. The Retina as a Window or Mirror of the Brain Changes Detected in Alzheimer's Disease: Critical Aspects to Unravel. Molecular Neurobiology. PMID 30612332 DOI: 10.1007/s12035-018-1461-6  0.442
2019 Rodrigues-Neves AC, Carecho R, Baptista F, Moreira P, Ambrósio A. Can the retina show similar molecular and cellular changes as the brain in an animal model of Alzheimer’s disease? Frontiers in Cellular Neuroscience. 13. DOI: 10.3389/Conf.Fncel.2019.01.00020  0.36
2019 Bernardes R, Ferreira H, Martins J, Moreira PI, Castelo‐Branco M, Ambrósio AF, Serranho P. Retinal thickness of the triple‐transgenic mice model of Alzheimer\’s disease at the age of one month Acta Ophthalmologica. 97. DOI: 10.1111/J.1755-3768.2019.5467  0.334
2018 Pinho TS, Correia SC, Perry G, Ambrósio AF, Moreira PI. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30412792 DOI: 10.1016/J.Bbadis.2018.10.037  0.752
2018 Cardoso S, Moreira PI. Diabesity and brain disturbances: A metabolic perspective. Molecular Aspects of Medicine. PMID 30321556 DOI: 10.1016/j.mam.2018.10.002  0.363
2018 Carvalho C, Moreira PI. Oxidative Stress: A Major Player in Cerebrovascular Alterations Associated to Neurodegenerative Events. Frontiers in Physiology. 9: 806. PMID 30018565 DOI: 10.3389/fphys.2018.00806  0.5
2018 Duarte AI, Sjögren M, Santos MS, Oliveira CR, Moreira PI, Björkqvist M. Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington's Disease. Scientific Reports. 8: 8961. PMID 29895889 DOI: 10.1038/s41598-018-27121-w  0.339
2018 Coimbra JRM, Marques DFF, Baptista SJ, Pereira CMF, Moreira PI, Dinis TCP, Santos AE, Salvador JAR. Highlights in BACE1 Inhibitors for Alzheimer's Disease Treatment. Frontiers in Chemistry. 6: 178. PMID 29881722 DOI: 10.3389/fchem.2018.00178  0.461
2018 Pinho TS, Verde DM, Correia SC, Cardoso SM, Moreira PI. O-GlcNAcylation and neuronal energy status: implications for Alzheimer's disease. Ageing Research Reviews. PMID 29787816 DOI: 10.1016/J.Arr.2018.05.003  0.711
2018 Perry G, Avila J, Moreira PI, Sorensen AA, Tabaton M. Preface. Journal of Alzheimer's Disease : Jad. PMID 29782320 DOI: 10.3233/JAD-179945  0.545
2018 Moreira PI. Sweet Mitochondria: A Shortcut to Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 62: 1391-1401. PMID 29562542 DOI: 10.3233/JAD-170931  0.486
2018 Mendes D, Oliveira MM, Moreira PI, Coutinho J, Nunes FM, Pereira DM, Valentão P, Andrade PB, Videira RA. Beneficial effects of white wine polyphenols-enriched diet on Alzheimer's disease-like pathology. The Journal of Nutritional Biochemistry. 55: 165-177. PMID 29525608 DOI: 10.1016/j.jnutbio.2018.02.001  0.441
2018 Duarte AI, Santos MS, Oliveira CR, Moreira PI. Brain insulin signalling, glucose metabolism and females' reproductive aging: A dangerous triad in Alzheimer's disease. Neuropharmacology. PMID 29471055 DOI: 10.1016/j.neuropharm.2018.01.044  0.442
2018 Marques-Aleixo I, Santos-Alves E, Oliveira PJ, Moreira PI, Magalhães J, Ascensão A. The beneficial role of exercise in mitigating doxorubicin-induced Mitochondrionopathy. Biochimica Et Biophysica Acta. PMID 29408395 DOI: 10.1016/j.bbcan.2018.01.002  0.331
2018 Duarte AI, Sjögren M, Mena D, Alves IN, Santos MS, Oliveira CR, Moreira PI, Björkqvist M. I11 Effects of dual administration of liraglutide and ghrelin on brain mitochondrial metabolism in the r6/2 mouse Journal of Neurology, Neurosurgery, and Psychiatry. 89. DOI: 10.1136/Jnnp-2018-Ehdn.247  0.357
2018 Pinho BR, Duarte AI, Almeida LM, Canas PM, Moreira PI, Murphy MP, Oliveira JM. I10 Effects of MITOQ on behavioural and biochemical phenotypes of a huntington’s disease mouse model Journal of Neurology, Neurosurgery, and Psychiatry. 89. DOI: 10.1136/Jnnp-2018-Ehdn.246  0.336
2017 Cardoso S, Seiça R, Moreira PI. Diabesity and Brain Energy Metabolism: The Case of Alzheimer's Disease. Advances in Neurobiology. 19: 117-150. PMID 28933063 DOI: 10.1007/978-3-319-63260-5_5  0.404
2017 Cardoso S, Seiça RM, Moreira PI. Uncoupling Protein 2 Inhibition Exacerbates Glucose Fluctuation-Mediated Neuronal Effects. Neurotoxicity Research. PMID 28875237 DOI: 10.1007/s12640-017-9805-y  0.382
2017 Candeias E, Sebastião I, Cardoso S, Carvalho C, Santos MS, Oliveira CR, Moreira PI, Duarte AI. Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats. Molecular Neurobiology. PMID 28573460 DOI: 10.1007/s12035-017-0622-3  0.383
2017 Bastos P, Ferreira R, Manadas B, Moreira PI, Vitorino R. Insights into the human brain proteome: Disclosing the biological meaning of protein networks in cerebrospinal fluid. Critical Reviews in Clinical Laboratory Sciences. 1-20. PMID 28393582 DOI: 10.1080/10408363.2017.1299682  0.383
2017 Cardoso SM, Correia SC, Carvalho C, Moreira PI. Mitochondria in Alzheimer's Disease and Diabetes-Associated Neurodegeneration: License to Heal! Handbook of Experimental Pharmacology. PMID 28251365 DOI: 10.1007/164_2017_3  0.728
2017 Neves AC, Chiquita S, Carecho R, Campos E, Moreira P, Baptista F, Ambrósio F. Alzheimer's disease: can the retina be a window to the brain? Acta Ophthalmologica. 95. DOI: 10.1111/J.1755-3768.2017.01564  0.447
2016 Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ, Perry G, Bellinger FP. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology. Journal of Alzheimer's Disease : Jad. PMID 27802219 DOI: 10.3233/JAD-151208  0.539
2016 Candeias E, Duarte AI, Sebastião I, Fernandes MA, Plácido AI, Carvalho C, Correia S, Santos RX, Seiça R, Santos MS, Oliveira CR, Moreira PI. Middle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology. Molecular Neurobiology. PMID 27730513 DOI: 10.1007/S12035-016-0155-1  0.8
2016 Correia SC, Perry G, Moreira PI. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks. Biochimica Et Biophysica Acta. PMID 27460705 DOI: 10.1016/J.Bbadis.2016.07.010  0.734
2016 Cardoso S, Seiça RM, Moreira PI. Mitochondria as a target for neuroprotection: implications for Alzheimer´s disease. Expert Review of Neurotherapeutics. PMID 27366815 DOI: 10.1080/14737175.2016.1205488  0.491
2016 Cardoso S, Carvalho C, Correia SC, Seiça RM, Moreira PI. Alzheimeŕs disease: From mitochondrial perturbations to mitochondrial medicine. Brain Pathology (Zurich, Switzerland). PMID 27327899 DOI: 10.1111/Bpa.12402  0.732
2016 Moreira P. Energy demand and energy supply in Alzheimer's Disease. An Introduction. Brain Pathology (Zurich, Switzerland). PMID 27327396 DOI: 10.1111/bpa.12398  0.342
2016 Plácido AI, Pereira CM, Correira SC, Carvalho C, Oliveira CR, Moreira PI. Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells. Molecular Neurobiology. PMID 26732598 DOI: 10.1007/s12035-015-9640-1  0.458
2016 Alves MG, Almeida S, Nunes AR, Sousa M, Moreira PI, Oliveira PF, Silva BM. Polyphenols As Protective Agents Against Neurotoxicity And Neurodegeneration: The Case Of Tea Polyphenols Journal of the International Society of Antioxidants in Nutrition & Health. 3. DOI: 10.18143/Jisanh_V3I4_1422  0.313
2015 Marques-Aleixo I, Santos-Alves E, Balça MM, Moreira PI, Oliveira PJ, Magalhães J, Ascensão A. Physical exercise mitigates doxorubicin-induced brain cortex and cerebellum mitochondrial alterations and cellular quality control signaling. Mitochondrion. 26: 43-57. PMID 26678157 DOI: 10.1016/j.mito.2015.12.002  0.441
2015 Candeias EM, Sebastião IC, Cardoso SM, Correia SC, Carvalho CI, Plácido AI, Santos MS, Oliveira CR, Moreira PI, Duarte AI. Gut-brain connection: The neuroprotective effects of the anti-diabetic drug liraglutide. World Journal of Diabetes. 6: 807-27. PMID 26131323 DOI: 10.4239/Wjd.V6.I6.807  0.685
2015 Marques-Aleixo I, Santos-Alves E, Balça MM, Rizo-Roca D, Moreira PI, Oliveira PJ, Magalhães J, Ascensão A. Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto(mito)phagy markers. Neuroscience. 301: 480-95. PMID 26116519 DOI: 10.1016/j.neuroscience.2015.06.027  0.419
2015 Carvalho C, Correia SC, Cardoso S, Plácido AI, Candeias E, Duarte AI, Moreira PI. The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases. Expert Review of Neurotherapeutics. 15: 867-84. PMID 26092668 DOI: 10.1586/14737175.2015.1058160  0.743
2015 Carvalho C, Santos MS, Oliveira CR, Moreira PI. Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers. Biochimica Et Biophysica Acta. 1852: 1665-75. PMID 25960150 DOI: 10.1016/j.bbadis.2015.05.001  0.442
2015 Placido AI, Pereira CM, Duarte AI, Candeias E, Correia SC, Carvalho C, Cardoso S, Oliveira CR, Moreira PI. Modulation of endoplasmic reticulum stress: an opportunity to prevent neurodegeneration? Cns & Neurological Disorders Drug Targets. 14: 518-33. PMID 25921746 DOI: 10.2174/1871527314666150429112353  0.706
2015 Nunes AR, Alves MG, Tomás GD, Conde VR, Cristóvão AC, Moreira PI, Oliveira PF, Silva BM. Daily consumption of white tea (Camellia sinensis (L.)) improves the cerebral cortex metabolic and oxidative profile in prediabetic Wistar rats. The British Journal of Nutrition. 113: 832-42. PMID 25716141 DOI: 10.1017/S0007114514004395  0.322
2015 Correia SC, Resende R, Moreira PI, Pereira CM. Alzheimer's disease-related misfolded proteins and dysfunctional organelles on autophagy menu. Dna and Cell Biology. 34: 261-73. PMID 25664381 DOI: 10.1089/dna.2014.2757  0.722
2015 Monteiro-Cardoso VF, Castro M, Oliveira MM, Moreira PI, Peixoto F, Videira RA. Age-dependent biochemical dysfunction in skeletal muscle of triple-transgenic mouse model of Alzheimer`s disease. Current Alzheimer Research. 12: 100-15. PMID 25654504 DOI: 10.2174/1567205012666150204124852  0.398
2015 Carvalho C, Correia SC, Perry G, Castellani RJ, Moreira PI. Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview. Journal of Neural Transmission (Vienna, Austria : 1996). PMID 25608860 DOI: 10.1007/S00702-015-1367-7  0.811
2015 Sena CM, Pereira AM, Carvalho C, Fernandes R, Seiça RM, Oliveira CR, Moreira PI. Type 2 diabetes aggravates Alzheimer's disease-associated vascular alterations of the aorta in mice. Journal of Alzheimer's Disease : Jad. 45: 127-38. PMID 25471187 DOI: 10.3233/JAD-141008  0.412
2015 Cardoso S, Correia S, Carvalho C, Candeias E, Plácido AI, Duarte AI, Seiça RM, Moreira PI. Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection. Journal of Bioenergetics and Biomembranes. 47: 119-31. PMID 25217852 DOI: 10.1007/S10863-014-9580-X  0.714
2015 Monteiro-Cardoso VF, Oliveira MM, Melo T, Domingues MR, Moreira PI, Ferreiro E, Peixoto F, Videira RA. Cardiolipin profile changes are associated to the early synaptic mitochondrial dysfunction in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 43: 1375-92. PMID 25182746 DOI: 10.3233/JAD-141002  0.443
2015 Plácido AI, Oliveira CR, Moreira PI, Pereira CM. Enhanced amyloidogenic processing of amyloid precursor protein and cell death under prolonged endoplasmic reticulum stress in brain endothelial cells. Molecular Neurobiology. 51: 571-90. PMID 25128025 DOI: 10.1007/s12035-014-8819-1  0.451
2015 Fonseca AC, Moreira PI, Oliveira CR, Cardoso SM, Pinton P, Pereira CF. Amyloid-beta disrupts calcium and redox homeostasis in brain endothelial cells. Molecular Neurobiology. 51: 610-22. PMID 24833600 DOI: 10.1007/S12035-014-8740-7  0.466
2015 Carvalho C, Correia SC, Cardoso S, Plácido AI, Candeias E, Duarte AI, Moreira PI. The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases Expert Review of Neurotherapeutics. 15: 867-884. DOI: 10.1586/14737175.2015.1058160  0.727
2015 Silva B, Alves M, Nunes A, Dias T, Moreira P, Oliveira P. White tea (Camellia sinensis) consumption improves heart and brain glycolytic and oxidative profiles in prediabetic rats Planta Medica. 81. DOI: 10.1055/S-0035-1565707  0.353
2015 Perry G, Perry EA, Moreira PI, Correia SS, Castellani RJ, Wang X, Lee H, Zhu X. P3-029: Oxidative damage is correlated with mitochondrial autophagy Alzheimer's & Dementia. 11: P630-P630. DOI: 10.1016/J.Jalz.2015.06.895  0.641
2015 Correia SC, Moreira PI, Perry G. Autophagy in alzheimer’s disease: A cleaning service out-of-order? Toxicity and Autophagy in Neurodegenerative Disorders. 123-142. DOI: 10.1007/978-3-319-13939-5_7  0.748
2014 Nunes AR, Alves MG, Moreira PI, Oliveira PF, Silva BM. Can Tea Consumption be a Safe and Effective Therapy Against Diabetes Mellitus-Induced Neurodegeneration? Current Neuropharmacology. 12: 475-89. PMID 25977676 DOI: 10.2174/1570159X13666141204220539  0.442
2014 Moreira PI. Metformin in the diabetic brain: friend or foe? Annals of Translational Medicine. 2: 54. PMID 25333029 DOI: 10.3978/j.issn.2305-5839.2014.06.10  0.322
2014 Carvalho C, Correia SC, Santos MS, Baldeiras I, Oliveira CR, Seica R, Moreira PI. Vascular, oxidative, and synaptosomal abnormalities during aging and the progression of type 2 diabetes. Current Neurovascular Research. 11: 330-9. PMID 25182811 DOI: 10.2174/1567202611666140903122801  0.667
2014 Sebastião I, Candeias E, Santos MS, de Oliveira CR, Moreira PI, Duarte AI. Insulin as a Bridge between Type 2 Diabetes and Alzheimer Disease - How Anti-Diabetics Could be a Solution for Dementia. Frontiers in Endocrinology. 5: 110. PMID 25071725 DOI: 10.3389/fendo.2014.00110  0.72
2014 Santos RX, Correia SC, Alves MG, Oliveira PF, Cardoso S, Carvalho C, Seiça R, Santos MS, Moreira PI. Mitochondrial quality control systems sustain brain mitochondrial bioenergetics in early stages of type 2 diabetes. Molecular and Cellular Biochemistry. 394: 13-22. PMID 24833464 DOI: 10.1007/S11010-014-2076-5  0.802
2014 Plácido AI, Pereira CM, Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, Oliveira CR, Moreira PI. The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: implications for Alzheimer's disease. Biochimica Et Biophysica Acta. 1842: 1444-53. PMID 24832819 DOI: 10.1016/J.Bbadis.2014.05.003  0.808
2014 Cardoso S, Carvalho C, Marinho R, Simões A, Sena CM, Matafome P, Santos MS, Seiça RM, Moreira PI. Effects of methylglyoxal and pyridoxamine in rat brain mitochondria bioenergetics and oxidative status. Journal of Bioenergetics and Biomembranes. 46: 347-55. PMID 24831520 DOI: 10.1007/s10863-014-9551-2  0.405
2014 Santos RX, Correia SC, Alves MG, Oliveira PF, Cardoso S, Carvalho C, Duarte AI, Santos MS, Moreira PI. Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats. Biochimica Et Biophysica Acta. 1842: 1154-66. PMID 24747740 DOI: 10.1016/J.Bbadis.2014.04.011  0.781
2014 Rato L, Duarte AI, Tomás GD, Santos MS, Moreira PI, Socorro S, Cavaco JE, Alves MG, Oliveira PF. Pre-diabetes alters testicular PGC1-α/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress. Biochimica Et Biophysica Acta. 1837: 335-44. PMID 24361842 DOI: 10.1016/j.bbabio.2013.12.008  0.424
2014 Carvalho C, Katz PS, Dutta S, Katakam PV, Moreira PI, Busija DW. Increased susceptibility to amyloid-β toxicity in rat brain microvascular endothelial cells under hyperglycemic conditions. Journal of Alzheimer's Disease : Jad. 38: 75-83. PMID 23948922 DOI: 10.3233/JAD-130464  0.402
2014 Correia SC, Santos MS, Moreira PI. S2.P5Adaptive reprogramming of brain mitochondrial biology during preconditioning prevents the sporadic Alzheimer's disease-like phenotype Biochimica Et Biophysica Acta. 1837. DOI: 10.1016/J.Bbabio.2014.05.293  0.744
2014 Rato L, Duarte AI, Tomás GD, Santos MS, Moreira PI, Socorro S, Cavaco JE, Alves MG, Oliveira PF. Pre-diabetes disrupts testicular PGC1-α/SIRT3 axis prompting oxidative stress Biochimica Et Biophysica Acta. 1837. DOI: 10.1016/J.Bbabio.2014.05.243  0.301
2014 Moreira PI. Mitochondria take center stage in Alzheimer's disease Biochimica Et Biophysica Acta. 1837. DOI: 10.1016/J.Bbabio.2014.05.134  0.461
2014 Castellani RJ, Zhu X, Perry G, Moreira PI. Alzheimer's Disease: An Overview Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.04491-3  0.67
2014 Castellani RJ, Moreira PI, Zhu X, Perry G. Alzheimer's Disease: Pathology and Pathogenesis Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00160-4  0.681
2014 Santos RX, Moreira PI. Mtor is a potential therapeutic target for alzheimer's disease Advances in Cognitive and Behavioral Sciences. 183-207.  0.698
2013 Correia SC, Perry G, Castellani R, Moreira PI. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease? Journal of Neurochemistry. 127: 4-6. PMID 24074055 DOI: 10.1111/Jnc.12406  0.745
2013 Mondragón-Rodríguez S, Perry G, Zhu X, Moreira PI, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease. Oxidative Medicine and Cellular Longevity. 2013: 940603. PMID 23936615 DOI: 10.1155/2013/940603  0.623
2013 González-Burgos E, Duarte AI, Carretero ME, Moreira PI, Gómez-Serranillos MP. Mitochondrial-targeted protective properties of isolated diterpenoids from sideritis spp. in response to the deleterious changes induced by H2O2. Journal of Natural Products. 76: 933-8. PMID 23675610 DOI: 10.1021/np400118d  0.45
2013 Moreira PI. High-sugar diets, type 2 diabetes and Alzheimer's disease. Current Opinion in Clinical Nutrition and Metabolic Care. 16: 440-5. PMID 23657152 DOI: 10.1097/MCO.0b013e328361c7d1  0.436
2013 Perry EA, Castellani RJ, Moreira PI, Nunomura A, Lui Q, Harris PL, Sayre LM, Szweda PA, Szweda LI, Zhu X, Smith MA, Perry G. Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links. Free Radical Research. 47: 507-10. PMID 23566300 DOI: 10.3109/10715762.2013.794265  0.77
2013 Correia SC, Carvalho C, Cardoso S, Santos RX, Plácido AI, Candeias E, Duarte AI, Moreira PI. Defective HIF signaling pathway and brain response to hypoxia in neurodegenerative diseases: not an "iffy" question! Current Pharmaceutical Design. 19: 6809-22. PMID 23530518 DOI: 10.2174/1381612811319380013  0.802
2013 Cardoso S, Santos MS, Moreno A, Moreira PI. UCP2 and ANT differently modulate proton-leak in brain mitochondria of long-term hyperglycemic and recurrent hypoglycemic rats. Journal of Bioenergetics and Biomembranes. 45: 397-407. PMID 23504111 DOI: 10.1007/s10863-013-9503-2  0.358
2013 Carvalho C, Machado N, Mota PC, Correia SC, Cardoso S, Santos RX, Santos MS, Oliveira CR, Moreira PI. Type 2 diabetic and Alzheimer's disease mice present similar behavioral, cognitive, and vascular anomalies. Journal of Alzheimer's Disease : Jad. 35: 623-35. PMID 23478310 DOI: 10.3233/Jad-130005  0.788
2013 Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, Plácido A, Santos MS, Oliveira CR, Moreira PI. Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration. Biochimica Et Biophysica Acta. 1832: 527-41. PMID 23314196 DOI: 10.1016/J.Bbadis.2013.01.008  0.803
2013 Moreno AJ, Moreira PI, Custódio JB, Santos MS. Mechanism of inhibition of mitochondrial ATP synthase by 17β-estradiol. Journal of Bioenergetics and Biomembranes. 45: 261-70. PMID 23274738 DOI: 10.1007/s10863-012-9497-1  0.307
2013 Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxidants & Redox Signaling. 18: 2444-57. PMID 23216311 DOI: 10.1089/Ars.2012.5039  0.838
2013 Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. Current Alzheimer Research. 10: 406-19. PMID 23061885 DOI: 10.2174/1567205011310040006  0.822
2013 Cardoso S, Santos RX, Correia SC, Carvalho C, Santos MS, Baldeiras I, Oliveira CR, Moreira PI. Insulin-induced recurrent hypoglycemia exacerbates diabetic brain mitochondrial dysfunction and oxidative imbalance. Neurobiology of Disease. 49: 1-12. PMID 22940631 DOI: 10.1016/J.Nbd.2012.08.008  0.8
2013 Cardoso S, Correia SC, Santos RX, Carvalho C, Candeias E, Duarte AI, Plácido AI, Santos MS, Moreira PI. Hyperglycemia, hypoglycemia and dementia: role of mitochondria and uncoupling proteins. Current Molecular Medicine. 13: 586-601. PMID 22934852 DOI: 10.2174/1566524011313040010  0.824
2013 Carvalho C, Santos RX, Cardoso S, Correia SC, Moreira PI. Chronic hypoxia, type 2 diabetes and Alzheimer's disease: A dangerous triad Hypoxia: Causes, Types and Management. 21-34.  0.777
2012 Candeias E, Duarte AI, Carvalho C, Correia SC, Cardoso S, Santos RX, Plácido AI, Perry G, Moreira PI. The impairment of insulin signaling in Alzheimer's disease. Iubmb Life. 64: 951-7. PMID 23129399 DOI: 10.1002/Iub.1098  0.811
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Moreira PI, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.567
2012 Marques-Aleixo I, Oliveira PJ, Moreira PI, Magalhães J, Ascensão A. Physical exercise as a possible strategy for brain protection: evidence from mitochondrial-mediated mechanisms. Progress in Neurobiology. 99: 149-62. PMID 22940590 DOI: 10.1016/j.pneurobio.2012.08.002  0.441
2012 Alves MG, Oliveira PF, Socorro S, Moreira PI. Impact of diabetes in blood-testis and blood-brain barriers: resemblances and differences. Current Diabetes Reviews. 8: 401-12. PMID 22934551 DOI: 10.2174/157339912803529896  0.307
2012 Correia SC, Santos RX, Cardoso S, Carvalho C, Candeias E, Duarte AI, Plácido AI, Santos MS, Moreira PI. Alzheimer disease as a vascular disorder: where do mitochondria fit? Experimental Gerontology. 47: 878-86. PMID 22824543 DOI: 10.1016/J.Exger.2012.07.006  0.832
2012 Mondragón-Rodríguez S, Perry G, Zhu X, Moreira PI, Williams S. Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target? International Journal of Alzheimer's Disease. 2012: 276803. PMID 22779025 DOI: 10.1155/2012/276803  0.796
2012 Nunomura A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in aging and neurodegenerative disorders. Neurotoxicity Research. 22: 231-48. PMID 22669748 DOI: 10.1007/s12640-012-9331-x  0.78
2012 Duarte AI, Moreira PI, Oliveira CR. Insulin in central nervous system: more than just a peripheral hormone. Journal of Aging Research. 2012: 384017. PMID 22500228 DOI: 10.1155/2012/384017  0.378
2012 Castellani RJ, Moreira PI, Perry G, Zhu X. The role of iron as a mediator of oxidative stress in Alzheimer disease. Biofactors (Oxford, England). 38: 133-8. PMID 22447715 DOI: 10.1002/biof.1010  0.686
2012 Carvalho C, Cardoso S, Correia SC, Santos RX, Santos MS, Baldeiras I, Oliveira CR, Moreira PI. Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities. Diabetes. 61: 1234-42. PMID 22427376 DOI: 10.2337/Db11-1186  0.825
2012 Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases. Advances in Experimental Medicine and Biology. 724: 205-21. PMID 22411245 DOI: 10.1007/978-1-4614-0653-2_16  0.843
2012 Correia SC, Santos RX, Carvalho C, Cardoso S, Candeias E, Santos MS, Oliveira CR, Moreira PI. Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation. Brain Research. 1441: 64-78. PMID 22290178 DOI: 10.1016/J.Brainres.2011.12.063  0.812
2012 Moreira PI. Alzheimer's disease and diabetes: an integrative view of the role of mitochondria, oxidative stress, and insulin. Journal of Alzheimer's Disease : Jad. 30: S199-215. PMID 22269163 DOI: 10.3233/JAD-2011-111127  0.461
2012 Santos RX, Correia SC, Zhu X, Lee HG, Petersen RB, Nunomura A, Smith MA, Perry G, Moreira PI. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease. Free Radical Research. 46: 565-76. PMID 22149654 DOI: 10.3109/10715762.2011.648188  0.833
2012 Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PL, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radical Biology & Medicine. 52: 699-704. PMID 22137893 DOI: 10.1016/J.Freeradbiomed.2011.11.004  0.823
2012 Correia SC, Santos RX, Cardoso SM, Santos MS, Oliveira CR, Moreira PI. Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α. Neurobiology of Disease. 45: 206-18. PMID 21854848 DOI: 10.1016/J.Nbd.2011.08.005  0.796
2012 Perry EA, Castellani R, Moreira P, GeorgePerry. A New Age in Metabolism Metabolomics. 2. DOI: 10.4172/2153-0769.1000E118  0.502
2011 Liu Q, Xie F, Alvarado-Diaz A, Smith MA, Moreira PI, Zhu X, Perry G. Neurofilamentopathy in neurodegenerative diseases. The Open Neurology Journal. 5: 58-62. PMID 21915226 DOI: 10.2174/1874205X01105010058  0.721
2011 Correia SC, Cardoso S, Santos RX, Carvalho C, Santos MS, Perry G, Smith MA, Moreira PI. New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection. Current Pharmaceutical Design. 17: 3381-9. PMID 21902670 DOI: 10.2174/138161211798072490  0.819
2011 Moreira PI, Oliveira CR. Mitochondria as potential targets in antidiabetic therapy. Handbook of Experimental Pharmacology. 331-56. PMID 21484578 DOI: 10.1007/978-3-642-17214-4_14  0.384
2011 Santos RX, Correia SC, Cardoso S, Carvalho C, Santos MS, Moreira PI. Effects of rapamycin and TOR on aging and memory: implications for Alzheimer's disease. Journal of Neurochemistry. 117: 927-36. PMID 21447003 DOI: 10.1111/J.1471-4159.2011.07262.X  0.782
2011 Santos RX, Correia SC, Carvalho C, Cardoso S, Santos MS, Moreira PI. Mitophagy in neurodegeneration: an opportunity for therapy? Current Drug Targets. 12: 790-9. PMID 21269269 DOI: 10.2174/138945011795528813  0.831
2011 Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? Ageing Research Reviews. 10: 264-73. PMID 21262392 DOI: 10.1016/J.Arr.2011.01.001  0.808
2011 Moreira PI, Custódio JB, Nunes E, Oliveira PJ, Moreno A, Seiça R, Oliveira CR, Santos MS. Mitochondria from distinct tissues are differently affected by 17β-estradiol and tamoxifen. The Journal of Steroid Biochemistry and Molecular Biology. 123: 8-16. PMID 20932907 DOI: 10.1016/j.jsbmb.2010.09.004  0.326
2011 Cardoso S, Carvalho C, Santos R, Correia S, Santos MS, Seiça R, Oliveira CR, Moreira PI. Impact of STZ-induced hyperglycemia and insulin-induced hypoglycemia in plasma amino acids and cortical synaptosomal neurotransmitters. Synapse (New York, N.Y.). 65: 457-66. PMID 20853444 DOI: 10.1002/Syn.20863  0.748
2011 Cardoso S, Santos RX, Carvalho C, Correia S, Santos MS, Moreira PI. Mitochondrial Uncoupling Proteins and Oxidative Stress: Implications for Diabetes and Neurodegeneration Free Radicals and Antioxidants. 1: 4-14. DOI: 10.5530/Ax.2011.2.3  0.823
2011 Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Zhu X, Smith MA, Perry G. Association of mitochondrial signaling in Alzheimer's disease and hypoxia Molecular Aspects of Neurodegeneration and Neuroprotection. 50-61. DOI: 10.2174/978160805092511101010050  0.827
2011 Correia S, Casadesus G, LaManna J, Perry G, Zhu X, Smith M, Moreira P. P3-290: Neuroprotective effects of hypoxic preconditioning on streptozotocin-induced animal model of sporadic Alzheimer's disease Alzheimer's & Dementia. 7: S609-S609. DOI: 10.1016/J.Jalz.2011.05.1732  0.768
2011 Correia S, Perry G, Zhu X, Smith M, Moreira P. P3-146: Decline in mitochondrial bioenergetics underlies central insulin resistance in streptozocin-induced model of sporadic Alzheimer's disease Alzheimer's & Dementia. 7: S562-S562. DOI: 10.1016/J.Jalz.2011.05.1586  0.788
2011 Collins GH, Mondragón-Rodríguez S, Nunomura A, Zhu X, Moreira PI, Smith MA. Oxidative Stress and Balance in Neurodegenerative Diseases Neurodegeneration: the Molecular Pathology of Dementia and Movement Disorders: Second Edition. 10-12. DOI: 10.1002/9781444341256.ch3  0.825
2011 Carvalho C, Correia SC, Santos RX, Cardoso S, Santos MS, Moreira PI. Diabetes, mitochondria and brain endothelium dysfunction: A dangerous triad for neurodegeneration? Mitochondria: Structure, Functions and Dysfunctions. 553-577.  0.762
2011 Cardoso S, Carvalho C, Correia S, Santos RX, Santos MS, Moreira PI. Mitochondrial uncoupling proteins - therapeutic targets in neurodegeneration? Neurodegeneration: Theory, Disorders and Treatments. 107-124.  0.771
2010 Carvalho C, Santos MS, Baldeiras I, Oliveira CR, Seiça R, Moreira PI. Chronic hypoxia potentiates age-related oxidative imbalance in brain vessels and synaptosomes. Current Neurovascular Research. 7: 288-300. PMID 20854250 DOI: 10.2174/156720210793180765  0.361
2010 Correia SC, Carvalho C, Cardoso S, Santos RX, Santos MS, Oliveira CR, Perry G, Zhu X, Smith MA, Moreira PI. Mitochondrial preconditioning: a potential neuroprotective strategy. Frontiers in Aging Neuroscience. 2. PMID 20838473 DOI: 10.3389/Fnagi.2010.00138  0.834
2010 Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. Alzheimer's disease: diverse aspects of mitochondrial malfunctioning. International Journal of Clinical and Experimental Pathology. 3: 570-81. PMID 20661404  0.849
2010 Cardoso S, Santos MS, Seiça R, Moreira PI. Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. Biochimica Et Biophysica Acta. 1802: 942-51. PMID 20620209 DOI: 10.1016/j.bbadis.2010.07.001  0.349
2010 Moreira PI, Santos RX, Zhu X, Lee HG, Smith MA, Casadesus G, Perry G. Autophagy in Alzheimer's disease. Expert Review of Neurotherapeutics. 10: 1209-18. PMID 20586699 DOI: 10.1586/Ern.10.84  0.852
2010 Santos RX, Cardoso S, Correia S, Carvalho C, Santos MS, Moreira PI. Targeting autophagy in the brain: a promising approach? Central Nervous System Agents in Medicinal Chemistry. 10: 158-68. PMID 20518730 DOI: 10.2174/187152410791196350  0.812
2010 Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondria: the missing link between preconditioning and neuroprotection. Journal of Alzheimer's Disease : Jad. 20: S475-85. PMID 20463394 DOI: 10.3233/Jad-2010-100669  0.817
2010 Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 20: S401-12. PMID 20463393 DOI: 10.3233/Jad-2010-100666  0.849
2010 Correia SC, Santos RX, Cardoso S, Carvalho C, Santos MS, Oliveira CR, Moreira PI. Effects of estrogen in the brain: is it a neuroprotective agent in Alzheimer's disease? Current Aging Science. 3: 113-26. PMID 20167003 DOI: 10.2174/1874609811003020113  0.803
2010 Moreira PI, Sayre LM, Zhu X, Nunomura A, Smith MA, Perry G. Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease. Methods in Molecular Biology (Clifton, N.J.). 610: 419-34. PMID 20013193 DOI: 10.1007/978-1-60327-029-8_25  0.744
2010 Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochimica Et Biophysica Acta. 1802: 2-10. PMID 19853658 DOI: 10.1016/j.bbadis.2009.10.006  0.729
2010 Moreira PI, Zhu X, Wang X, Lee HG, Nunomura A, Petersen RB, Perry G, Smith MA. Mitochondria: a therapeutic target in neurodegeneration. Biochimica Et Biophysica Acta. 1802: 212-20. PMID 19853657 DOI: 10.1016/J.Bbadis.2009.10.007  0.818
2010 Correia SC, Moreira PI. Hypoxia-inducible factor 1: a new hope to counteract neurodegeneration? Journal of Neurochemistry. 112: 1-12. PMID 19845827 DOI: 10.1111/J.1471-4159.2009.06443.X  0.701
2010 Cardoso SM, Pereira CF, Moreira PI, Arduino DM, Esteves AR, Oliveira CR. Mitochondrial control of autophagic lysosomal pathway in Alzheimer's disease. Experimental Neurology. 223: 294-8. PMID 19559703 DOI: 10.1016/J.Expneurol.2009.06.008  0.541
2010 Moreira PI. Mitochondrial dysfunction and oxidative stress in Alzheimer's disease European Neurological Review. 5: 17-21. DOI: 10.17925/Enr.2010.05.01.17  0.459
2010 Castellani R, Moreira P, Aliev G, Shenk J, Siedlak S, Harris P, Sayre L, Szweda L, Zhu X, Smith M, Perry G, Szweda P. Hydroxynonenal-Generated Crosslinking Fluorophore and Mitochondria-derived Lipoic Acid Accumulation in Alzheimer Disease Reveal a Dichotomy of Protein Turnover Microscopy and Microanalysis. 16: 1014-1015. DOI: 10.1017/S1431927610059350  0.82
2010 Shenk JC, Smith MA, Castellani RJ, Moreira P, Aliev G, Siedlak SL, Harris PL, Sayre L, Szweda PA, Szweda LI, Perry G. P1-196: Lipid peroxidation markers are associated with granulovacuolar degeneration but not lipofuscin formation Alzheimer's & Dementia. 6: S230-S230. DOI: 10.1016/J.Jalz.2010.05.746  0.764
2010 Correia SC, Santos RX, Santos MS, Moreira PI. Mitochondrial reactive oxygen species preconditioning protects brain cells against hyperglycemia Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1901  0.784
2010 Cardoso S, Carvalho C, Santos MS, Oliveira CR, Moreira PI. Mitochondrial dysfunction and oxidative status impairment: A comparative study between male and female 3xTg-AD mice Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1306  0.394
2010 Carvalho C, Santos MS, Oliveira C, Moreira P. Insulin resistance induced by sucrose intake exacerbates brain mitochondrial dysfunction in a mouse model of Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1303  0.467
2009 Cardoso S, Santos R, Correia S, Carvalho C, Zhu X, Lee HG, Casadesus G, Smith MA, Perry G, Moreira PI. Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets. Pharmaceuticals (Basel, Switzerland). 2: 250-286. PMID 27713238 DOI: 10.3390/Ph2030250  0.804
2009 Perry G, Moreira PI, Siedlak SL, Nunomura A, Zhu X, Smith MA. Natural oxidant balance in Parkinson disease. Archives of Neurology. 66: 1445. PMID 20008647 DOI: 10.1001/Archneurol.2009.261  0.755
2009 Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Clark TA, Zhu X, Smith MA, Perry G. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia. Journal of Bioenergetics and Biomembranes. 41: 433-40. PMID 19830532 DOI: 10.1007/S10863-009-9247-1  0.848
2009 Moreira PI, Cardoso SM, Pereira CM, Santos MS, Oliveira CR. Mitochondria as a therapeutic target in Alzheimer's disease and diabetes. Cns & Neurological Disorders Drug Targets. 8: 492-511. PMID 19702564 DOI: 10.2174/187152709789824651  0.472
2009 Carvalho C, Santos RX, Cardoso S, Correia S, Oliveira PJ, Santos MS, Moreira PI. Doxorubicin: the good, the bad and the ugly effect. Current Medicinal Chemistry. 16: 3267-85. PMID 19548866 DOI: 10.2174/092986709788803312  0.748
2009 Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA, Zhu X, Moreira PI. Insulin is a two-edged knife on the brain. Journal of Alzheimer's Disease : Jad. 18: 483-507. PMID 19542630 DOI: 10.3233/Jad-2009-1155  0.792
2009 Moreira PI, Duarte AI, Santos MS, Rego AC, Oliveira CR. An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 16: 741-61. PMID 19387110 DOI: 10.3233/JAD-2009-0972  0.528
2009 Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathologica. 118: 151-66. PMID 19271225 DOI: 10.1007/s00401-009-0508-1  0.778
2009 Perry G, Zhu X, Moreira PI, Smith MA. Altered redox balance in disease: can we change the new equilibria? Annals of Neurology. 65: 121-3. PMID 19259960 DOI: 10.1002/ana.21608  0.627
2009 Santos RX, Cardoso S, Silva S, Correia S, Carvalho C, Crisóstomo J, Rodrigues L, Amaral C, Louro T, Matafome P, Santos MS, Proença T, Duarte AI, Seiça R, Moreira PI. Food deprivation promotes oxidative imbalance in rat brain. Journal of Food Science. 74: H8-H14. PMID 19200099 DOI: 10.1111/J.1750-3841.2008.00982.X  0.765
2009 Friedlich AL, Smith MA, Zhu X, Takeda A, Nunomura A, Moreira PI, Perry G. Oxidative Stress in Parkinson`s Disease The Open Pathology Journal. 3: 38-42. DOI: 10.2174/1874375700903010038  0.825
2009 Moreira PI, Santos MS, Seiça R, Oliveira CR. Diabetes is a risk factor for Alzheimer disease: The role of mitochondria Journal of the Neurological Sciences. 283: 271. DOI: 10.1016/J.Jns.2009.02.123  0.404
2009 Shenk JC, Castellani RJ, Moreira P, Aliev G, Siedlak SL, Harris PL, Sayre L, Szweda PA, Smith MA, Perry G. P2-186: Hydroxynonenal generated crosslinking fluorophores accumulate in Alzheimer's disease Alzheimer's & Dementia. 5: P315-P315. DOI: 10.1016/J.Jalz.2009.04.498  0.822
2009 Nunomura A, Takeda A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Neurofibrillary tangle formation as a protective response to oxidative stress in Alzheimer's disease Current Hypotheses and Research Milestones in Alzheimer's Disease. 103-113. DOI: 10.1007/978-0-387-87995-6_9  0.769
2009 Marlatt MW, Moreira PI, Lee Hg, Casadesus G, Castellani RJ, Takeda A, Nunomura A, Zhu X, Perry G, Smith MA. Therapeutic opportunities in Alzheimer disease: Current concepts Frontiers in Medicinal Chemistry. 4: 767-788.  0.787
2008 Castellani RJ, Nunomura A, Rolston RK, Moreira PI, Takeda A, Perry G, Smith MA. Sublethal RNA oxidation as a mechanism for neurodegenerative disease. International Journal of Molecular Sciences. 9: 789-806. PMID 19325784 DOI: 10.3390/Ijms9050789  0.792
2008 Su B, Wang X, Nunomura A, Moreira PI, Lee HG, Perry G, Smith MA, Zhu X. Oxidative stress signaling in Alzheimer's disease. Current Alzheimer Research. 5: 525-32. PMID 19075578 DOI: 10.2174/156720508786898451  0.808
2008 Wang X, Su B, Siedlak SL, Moreira PI, Fujioka H, Wang Y, Casadesus G, Zhu X. Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proceedings of the National Academy of Sciences of the United States of America. 105: 19318-23. PMID 19050078 DOI: 10.1073/Pnas.0804871105  0.726
2008 Aliev G, Obrenovich ME, Reddy VP, Shenk JC, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Reviews in Medicinal Chemistry. 8: 1395-406. PMID 18991755 DOI: 10.2174/138955708786369582  0.831
2008 Correia S, Carvalho C, Santos MS, Seiça R, Oliveira CR, Moreira PI. Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview. Mini Reviews in Medicinal Chemistry. 8: 1343-54. PMID 18991752 DOI: 10.2174/138955708786369546  0.617
2008 Perry G, Castellani RJ, Moreira PI, Lee HG, Zhu X, Smith MA. Pathology's new role: defining disease process and protective responses. International Journal of Clinical and Experimental Pathology. 1: 1-4. PMID 18784818  0.707
2008 Cardoso S, Santos RX, Carvalho C, Correia S, Pereira GC, Pereira SS, Oliveira PJ, Santos MS, Proença T, Moreira PI. Doxorubicin increases the susceptibility of brain mitochondria to Ca(2+)-induced permeability transition and oxidative damage. Free Radical Biology & Medicine. 45: 1395-402. PMID 18775776 DOI: 10.1016/J.Freeradbiomed.2008.08.008  0.799
2008 Correia S, Carvalho C, Santos MS, Proença T, Nunes E, Duarte AI, Monteiro P, Seiça R, Oliveira CR, Moreira PI. Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes. Medicinal Chemistry (ShäRiqah (United Arab Emirates)). 4: 358-64. PMID 18673148 DOI: 10.2174/157340608784872299  0.661
2008 Resende R, Moreira PI, Proença T, Deshpande A, Busciglio J, Pereira C, Oliveira CR. Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease. Free Radical Biology & Medicine. 44: 2051-7. PMID 18423383 DOI: 10.1016/J.Freeradbiomed.2008.03.012  0.503
2008 Moreira PI, Santos MS, Oliveira CR, Shenk JC, Nunomura A, Smith MA, Zhu X, Perry G. Alzheimer disease and the role of free radicals in the pathogenesis of the disease. Cns & Neurological Disorders Drug Targets. 7: 3-10. PMID 18289026 DOI: 10.2174/187152708783885156  0.855
2008 Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G. Nucleic acid oxidation in Alzheimer disease. Free Radical Biology & Medicine. 44: 1493-505. PMID 18258207 DOI: 10.1016/J.Freeradbiomed.2008.01.002  0.839
2008 Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, ... ... Moreira PI, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 4: 151-75. PMID 18188003 DOI: 10.4161/Auto.5338  0.636
2008 Carvalho C, Correia S, Santos MS, Seiça R, Oliveira CR, Moreira PI. Metformin promotes isolated rat liver mitochondria impairment. Molecular and Cellular Biochemistry. 308: 75-83. PMID 17909944 DOI: 10.1007/S11010-007-9614-3  0.681
2008 Moreira PI, Santos MS, Siedlak SL, Harris P, Smith MA, Aliev G, Perry G, Oliveira CR. P4-185: Mitochondrial dysfunction in Alzheimer's disease Alzheimer's & Dementia. 4: T725-T725. DOI: 10.1016/J.Jalz.2008.05.2252  0.759
2008 Resende R, Moreira PI, Deshpande A, Busciglio J, Pereira C, Oliveira CR. P4-183: Increased oxidative stress is an early pathological feature in 3xTg-AD mice Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.2250  0.383
2007 Nunomura A, Moreira PI, Lee HG, Zhu X, Castellani RJ, Smith MA, Perry G. Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. Cns & Neurological Disorders Drug Targets. 6: 411-23. PMID 18220780 DOI: 10.2174/187152707783399201  0.818
2007 Nunomura A, Moreira PI, Takeda A, Smith MA, Perry G. Oxidative RNA damage and neurodegeneration. Current Medicinal Chemistry. 14: 2968-75. PMID 18220733 DOI: 10.2174/092986707782794078  0.736
2007 Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA, Perry G. Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. Journal of Alzheimer's Disease : Jad. 12: 195-206. PMID 17917164 DOI: 10.3233/Jad-2007-12210  0.673
2007 Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy. 3: 614-5. PMID 17786024 DOI: 10.4161/Auto.4872  0.863
2007 Moreira PI, Santos MS, Oliveira CR. Alzheimer's disease: a lesson from mitochondrial dysfunction. Antioxidants & Redox Signaling. 9: 1621-30. PMID 17678440 DOI: 10.1089/ars.2007.1703  0.554
2007 Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Autophagocytosis of mitochondria is prominent in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 66: 525-32. PMID 17549012 DOI: 10.1016/J.Jns.2009.02.162  0.848
2007 Castellani RJ, Moreira PI, Liu G, Dobson J, Perry G, Smith MA, Zhu X. Iron: the Redox-active center of oxidative stress in Alzheimer disease. Neurochemical Research. 32: 1640-5. PMID 17508283 DOI: 10.1007/S11064-007-9360-7  0.762
2007 Castellani RJ, Zhu X, Lee HG, Moreira PI, Perry G, Smith MA. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees? Expert Review of Neurotherapeutics. 7: 473-85. PMID 17492899 DOI: 10.1586/14737175.7.5.473  0.728
2007 Moreira PI, Custódio JB, Nunes E, Moreno A, Seiça R, Oliveira CR, Santos MS. Estradiol affects liver mitochondrial function in ovariectomized and tamoxifen-treated ovariectomized female rats. Toxicology and Applied Pharmacology. 221: 102-10. PMID 17397887 DOI: 10.1016/j.taap.2007.02.006  0.38
2007 Casadesus G, Moreira PI, Nunomura A, Siedlak SL, Bligh-Glover W, Balraj E, Petot G, Smith MA, Perry G. Indices of metabolic dysfunction and oxidative stress. Neurochemical Research. 32: 717-22. PMID 17342408 DOI: 10.1007/S11064-007-9296-Y  0.828
2007 Zhu X, Smith MA, Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. Journal of the Neurological Sciences. 257: 240-6. PMID 17337008 DOI: 10.1016/J.Jns.2007.01.039  0.847
2007 Moreira PI, Santos MS, Seiça R, Oliveira CR. Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes. Journal of the Neurological Sciences. 257: 206-14. PMID 17316694 DOI: 10.1016/j.jns.2007.01.017  0.534
2007 Liu Q, Xie F, Rolston R, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Prevention and treatment of Alzheimer disease and aging: antioxidants. Mini Reviews in Medicinal Chemistry. 7: 171-80. PMID 17305591 DOI: 10.2174/138955707779802552  0.803
2007 Perry G, Moreira PI, Siedlak SL, Santos MS, Oliveira CR, Fujioka H, Tabaton M, Nunomura A, Aliev G, Szweda LI, Smith MA. Mitochondrial autophagocytosis in Alzheimer disease Journal of Neuropathology and Experimental Neurology. 66: 434. DOI: 10.1097/01.Jnen.0000268871.37441.1B  0.848
2007 Perry G, Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA. Lipoic acid and N-acetyl cysteine protect against mitochondrial-related oxidative stress in fibroblasts from Alzheimer disease patients Journal of Neuropathology and Experimental Neurology. 66: 434. DOI: 10.1097/01.Jnen.0000268870.37441.52  0.694
2007 Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Erratum: Autophagocytosis of mitochondria is prominent in Alzheimer disease (Journal of Neuropathology and Experimental Neurology (2007) 66, (525-532)) Journal of Neuropathology and Experimental Neurology. 66. DOI: 10.1097/01.Jnen.0000263876.99435.Cb  0.826
2007 Moreira PI, Nunomura A, Honda K, Aliev G, Casadesus G, Zhu X, Smith MA, Perry G. The key role of oxidative stress in alzheimer's disease Oxidative Stress and Neurodegenerative Disorders. 267-281. DOI: 10.1016/B978-044452809-4/50153-8  0.837
2007 Moreira PI, Smith MA, Zhu X, Nunomura A, Perry G. The potential application of antioxidant agents in Alzheimer disease therapeutics Pharmacological Mechanisms in Alzheimer's Therapeutics. 194-211. DOI: 10.1007/978-0-387-71522-3_12  0.736
2006 Franco S, Blasco MA, Siedlak SL, Harris PL, Moreira PI, Perry G, Smith MA. Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2: 164-8. PMID 19595878 DOI: 10.1016/J.Jalz.2006.03.001  0.67
2006 Moreira PI, Rolo AP, Sena C, Seiça R, Oliveira CR, Santos MS. Insulin attenuates diabetes-related mitochondrial alterations: a comparative study. Medicinal Chemistry (ShäRiqah (United Arab Emirates)). 2: 299-308. PMID 16948477 DOI: 10.2174/157340606776930754  0.394
2006 Zhu X, Perry G, Moreira PI, Aliev G, Cash AD, Hirai K, Smith MA. Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease. Journal of Alzheimer's Disease : Jad. 9: 147-53. PMID 16873962 DOI: 10.3233/JAD-2006-9207  0.838
2006 Moreira PI, Cardoso SM, Santos MS, Oliveira CR. The key role of mitochondria in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 9: 101-10. PMID 16873957  0.432
2006 Nunomura A, Castellani RJ, Zhu X, Moreira PI, Perry G, Smith MA. Involvement of oxidative stress in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 631-41. PMID 16825950 DOI: 10.1097/01.jnen.0000228136.58062.bf  0.822
2006 Moreira PI, Zhu X, Nunomura A, Smith MA, Perry G. Therapeutic options in Alzheimer's disease. Expert Review of Neurotherapeutics. 6: 897-910. PMID 16784412 DOI: 10.1586/14737175.6.6.897  0.763
2006 Nunomura A, Castellani RJ, Lee HG, Moreira PI, Zhu X, Perry G, Smith MA. Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream. Science of Aging Knowledge Environment : Sage Ke. 2006: pe10. PMID 16672726 DOI: 10.1126/sageke.2006.8.pe10  0.825
2006 Moreira PI, Zhu X, Liu Q, Honda K, Siedlak SL, Harris PL, Smith MA, Perry G. Compensatory responses induced by oxidative stress in Alzheimer disease. Biological Research. 39: 7-13. PMID 16629160 DOI: 10.4067/S0716-97602006000100002  0.828
2006 Zhu X, Lee HG, Moreira PI, Smith MA, Perry G. Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice". Free Radical Biology & Medicine. 40: 737-9. PMID 16520226 DOI: 10.1016/j.freeradbiomed.2005.12.028  0.626
2006 Moreira PI, Zhu X, Lee HG, Honda K, Smith MA, Perry G. The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease. Mechanisms of Ageing and Development. 127: 501-6. PMID 16516950 DOI: 10.1016/j.mad.2006.01.024  0.799
2006 Moreira PI, Honda K, Zhu X, Nunomura A, Casadesus G, Smith MA, Perry G. Brain and brawn: parallels in oxidative strength. Neurology. 66: S97-101. PMID 16432155 DOI: 10.1212/01.wnl.0000192307.15103.83  0.835
2006 Moreira PI, Custódio J, Moreno A, Oliveira CR, Santos MS. Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure. The Journal of Biological Chemistry. 281: 10143-52. PMID 16410252 DOI: 10.1074/jbc.M510249200  0.319
2006 Moreira PI, Oliveira C. Foreword: Mitochondria in Alzheimer disease Journal of Alzheimer's Disease. 9: 99. DOI: 10.3233/Jad-2006-9201  0.53
2006 Moreira PI, Zhu X, Lee H, Nunomura A, Smith MA, Perry G. Therapeutic potential of oxidative stress reduction in Alzheimer's disease Future Neurology. 1: 1-4. DOI: 10.2217/14796708.1.1.1  0.7
2006 Smith MA, Moreira PI, Castellani RJ, Perry G. Symposium Brain Pathology. 14: 425-425. DOI: 10.1111/j.1750-3639.2004.tb00086.x  0.497
2006 Moreira PI, Siedlak SL, Santos MS, Oliveira CR, Fujioka H, Tabaton M, Nunomura A, Aliev G, Szweda LI, Zhu X, Smith MA, Perry G. O4-02-08: Mitochondrial autophagocytosis in Alzheimer disease Alzheimer's & Dementia. 2: S79-S79. DOI: 10.1016/J.Jalz.2006.05.307  0.829
2006 Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA, Perry G. P3-375: Lipoic acid and N -acetyl cysteine protect against mitochondrial-related oxidative stress in fibroblasts from Alzheimer disease patients Alzheimer's & Dementia. 2: S486-S486. DOI: 10.1016/J.Jalz.2006.05.1645  0.689
2005 Moreira PI, Honda K, Liu Q, Santos MS, Oliveira CR, Aliev G, Nunomura A, Zhu X, Smith MA, Perry G. Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Current Alzheimer Research. 2: 403-8. PMID 16248845 DOI: 10.2174/156720505774330537  0.844
2005 Sayre LM, Moreira PI, Smith MA, Perry G. Metal ions and oxidative protein modification in neurological disease. Annali Dell'Istituto Superiore Di Sanitã . 41: 143-64. PMID 16244388  0.667
2005 Moreira PI, Oliveira CR, Santos MS, Nunomura A, Honda K, Zhu X, Smith MA, Perry G. A second look into the oxidant mechanisms in Alzheimer's disease. Current Neurovascular Research. 2: 179-84. PMID 16181112 DOI: 10.2174/1567202053586758  0.844
2005 Moreira PI, Santos MS, Sena C, Nunes E, Seiça R, Oliveira CR. CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats. Experimental Neurology. 196: 112-9. PMID 16126199 DOI: 10.1016/j.expneurol.2005.07.012  0.436
2005 Cardoso SM, Moreira PI, Agostinho P, Pereira C, Oliveira CR. Neurodegenerative pathways in Parkinson's disease: therapeutic strategies. Current Drug Targets. Cns and Neurological Disorders. 4: 405-19. PMID 16101557 DOI: 10.2174/1568007054546072  0.379
2005 Pereira C, Agostinho P, Moreira PI, Cardoso SM, Oliveira CR. Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies. Current Drug Targets. Cns and Neurological Disorders. 4: 383-403. PMID 16101556 DOI: 10.2174/1568007054546117  0.45
2005 Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, et al. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathologica. 110: 232-8. PMID 16096758 DOI: 10.1007/S00401-005-1034-4  0.84
2005 Zhu X, Moreira PI, Smith MA, Perry G. Alzheimer's disease: an intracellular movement disorder? Trends in Molecular Medicine. 11: 391-3. PMID 16087404 DOI: 10.1016/j.molmed.2005.07.002  0.617
2005 Moreira PI, Smith MA, Zhu X, Nunomura A, Castellani RJ, Perry G. Oxidative stress and neurodegeneration. Annals of the New York Academy of Sciences. 1043: 545-52. PMID 16037277 DOI: 10.1196/annals.1333.062  0.818
2005 Marlatt MW, Webber KM, Moreira PI, Lee HG, Casadesus G, Honda K, Zhu X, Perry G, Smith MA. Therapeutic opportunities in Alzheimer disease: one for all or all for one? Current Medicinal Chemistry. 12: 1137-47. PMID 15892629 DOI: 10.2174/0929867053764644  0.828
2005 Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA. Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends in Molecular Medicine. 11: 164-9. PMID 15823754 DOI: 10.1016/J.Molmed.2005.02.008  0.802
2005 Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, et al. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. The Journal of Biological Chemistry. 280: 20978-86. PMID 15767256 DOI: 10.1074/Jbc.M500526200  0.797
2005 Moreira PI, Santos MS, Sena C, Seiça R, Oliveira CR. Insulin protects against amyloid beta-peptide toxicity in brain mitochondria of diabetic rats. Neurobiology of Disease. 18: 628-37. PMID 15755688 DOI: 10.1016/j.nbd.2004.10.017  0.406
2005 Moreira PI, Smith MA, Zhu X, Honda K, Lee HG, Aliev G, Perry G. Oxidative damage and Alzheimer's disease: are antioxidant therapies useful? Drug News & Perspectives. 18: 13-9. PMID 15753972 DOI: 10.1358/Dnp.2005.18.1.877164  0.825
2005 Liu Q, Smith MA, Avilá J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, et al. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radical Biology & Medicine. 38: 746-54. PMID 15721985 DOI: 10.1016/J.Freeradbiomed.2004.11.005  0.814
2005 Moreira PI, Custódio JB, Oliveira CR, Santos MS. Brain mitochondrial injury induced by oxidative stress-related events is prevented by tamoxifen. Neuropharmacology. 48: 435-47. PMID 15721176 DOI: 10.1016/j.neuropharm.2004.10.012  0.459
2005 Smith MA, Nunomura A, Lee HG, Zhu X, Moreira PI, Avila J, Perry G. Chronological primacy of oxidative stress in Alzheimer disease. Neurobiology of Aging. 26: 579-80. PMID 15708430 DOI: 10.1016/j.neurobiolaging.2004.09.021  0.773
2005 Webber KM, Smith MA, Lee HG, Harris PL, Moreira P, Perry G, Zhu X. Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease. Journal of Neuroscience Research. 79: 554-60. PMID 15635602 DOI: 10.1002/jnr.20380  0.651
2005 Moreira PI, Siedlak SL, Aliev G, Zhu X, Cash AD, Smith MA, Perry G. Oxidative stress mechanisms and potential therapeutics in Alzheimer disease. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 921-32. PMID 15583960 DOI: 10.1007/S00702-004-0242-8  0.825
2005 Baykal A, arigul FS, Suleymanla G, Moreira PI, Perry G, Smith MA, Aliciguzel Y. Ciprofloxacin Does Not Exert Nephrotoxicity in Rats American Journal of Infectious Diseases. 1: 145-148. DOI: 10.3844/Ajidsp.2005.145.148  0.542
2005 Honda K, Moreira PI, Liu Q, Siedlak SL, Zhu X, Smith MA, Perry G. Redox active iron at the center of oxidative stress in Alzheimer disease Letters in Drug Design and Discovery. 2: 479-482. DOI: 10.2174/1570180054771545  0.792
2005 Moreira P, Honda K, Liu Q, Aliev G, Oliveira C, Santos M, Zhu X, Smith M, Perry G. Alzheimers Disease and Oxidative Stress: The Old Problem Remains Unsolved Current Medicinal Chemistry-Central Nervous System Agents. 5: 51-62. DOI: 10.2174/1568015053202714  0.824
2004 Moreira PI, Smith MA, Zhu X, Santos MS, Oliveira CR, Perry G. Therapeutic potential of oxidant mechanisms in Alzheimer's disease. Expert Review of Neurotherapeutics. 4: 995-1004. PMID 15853526 DOI: 10.1586/14737175.4.6.995  0.735
2004 Liu Q, Xie F, Siedlak SL, Nunomura A, Honda K, Moreira PI, Zhua X, Smith MA, Perry G. Neurofilament proteins in neurodegenerative diseases. Cellular and Molecular Life Sciences : Cmls. 61: 3057-75. PMID 15583867 DOI: 10.1007/S00018-004-4268-8  0.823
2004 Lee HG, Moreira PI, Zhu X, Smith MA, Perry G. Staying connected: synapses in Alzheimer disease. The American Journal of Pathology. 165: 1461-4. PMID 15509517 DOI: 10.1016/S0002-9440(10)63404-9  0.612
2004 Moreira PI, Liu Q, Honda K, Smith MA, Santos MS, Oliveira CR. Is intraneuronal amyloid beta-peptide accumulation the trigger of Alzheimer's disease pathophysiology? Journal of Alzheimer's Disease : Jad. 6: 433-4; discussion 44. PMID 15495345 DOI: 10.3233/Jad-2004-6411  0.79
2004 Moreira PI, Custódio JB, Oliveira CR, Santos MS. Hydroxytamoxifen protects against oxidative stress in brain mitochondria. Biochemical Pharmacology. 68: 195-204. PMID 15183131 DOI: 10.1016/j.bcp.2004.03.019  0.443
2004 Moreira PI, Santos MS, Moreno AM, Proença T, Seiça R, Oliveira CR. Effect of streptozotocin-induced diabetes on rat brain mitochondria. Journal of Neuroendocrinology. 16: 32-8. PMID 14962073 DOI: 10.1111/j.1365-2826.2004.01107.x  0.404
2003 Pereira C, Agostinho P, Moreira PI, Duarte AI, Santos MS, Oliveira CR. [Neuroprotection strategies: effect of vinpocetine in vitro oxidative stress models]. Acta Mã©Dica Portuguesa. 16: 401-6. PMID 15631851 DOI: 10.20344/Amp.1220  0.485
2003 Moreira PI, Santos MS, Moreno AM, Seiça R, Oliveira CR. Increased vulnerability of brain mitochondria in diabetic (Goto-Kakizaki) rats with aging and amyloid-beta exposure. Diabetes. 52: 1449-56. PMID 12765956 DOI: 10.2337/diabetes.52.6.1449  0.362
2002 Moreira PI, Santos MS, Moreno A, Rego AC, Oliveira C. Effect of amyloid beta-peptide on permeability transition pore: a comparative study. Journal of Neuroscience Research. 69: 257-67. PMID 12111807 DOI: 10.1002/jnr.10282  0.311
2001 Moreira PI, Santos MS, Moreno A, Oliveira C. Amyloid beta-peptide promotes permeability transition pore in brain mitochondria. Bioscience Reports. 21: 789-800. PMID 12166828 DOI: 10.1023/A:1015536808304  0.347
2000 Moreira P, Pereira C, Santos MS, Oliveira C. Effect of zinc ions on the cytotoxicity induced by the amyloid beta-peptide. Antioxidants & Redox Signaling. 2: 317-325. PMID 11229535 DOI: 10.1089/Ars.2000.2.2-317  0.385
2000 Santos MS, Duarte AI, Moreira PI, Oliveira CR. Synaptosomal response to oxidative stress: effect of vinpocetine. Free Radical Research. 32: 57-66. PMID 10625217 DOI: 10.1080/10715760000300061  0.377
Low-probability matches (unlikely to be authored by this person)
2000 Pereira C, Moreira P, Seiça R, Santos MS, Oliveira CR. Susceptibility to β-Amyloid-Induced Toxicity Is Decreased in Goto-Kakizaki Diabetic Rats: Involvement of Oxidative Stress Experimental Neurology. 161: 383-391. PMID 10683303 DOI: 10.1006/Exnr.1999.7270  0.298
2015 Rato L, Alves MG, Duarte AI, Santos MS, Moreira PI, Cavaco JE, Oliveira PF. Testosterone deficiency induced by progressive stages of diabetes mellitus impairs glucose metabolism and favors glycogenesis in mature rat Sertoli cells. The International Journal of Biochemistry & Cell Biology. 66: 1-10. PMID 26148570 DOI: 10.1016/j.biocel.2015.07.001  0.297
2024 Fernandes T, Melo T, Conde T, Neves B, Domingues P, Resende R, Pereira CF, Moreira PI, Domingues MR. Mapping the lipidome in mitochondria-associated membranes (MAMs) in an in vitro model of Alzheimer's disease. Journal of Neurochemistry. PMID 38327008 DOI: 10.1111/jnc.16072  0.296
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Moreira PI, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.291
2011 Finley LW, Carracedo A, Lee J, Souza A, Egia A, Zhang J, Teruya-Feldstein J, Moreira PI, Cardoso SM, Clish CB, Pandolfi PP, Haigis MC. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization. Cancer Cell. 19: 416-28. PMID 21397863 DOI: 10.1016/J.Ccr.2011.02.014  0.282
2021 Cardoso S, Moreira PI. Insulin-Induced Recurrent Hypoglycemia Up-Regulates Glucose Metabolism in the Brain Cortex of Chemically Induced Diabetic Rats. International Journal of Molecular Sciences. 22. PMID 34948265 DOI: 10.3390/ijms222413470  0.278
2014 Alves MG, Martins AD, Vaz CV, Correia S, Moreira PI, Oliveira PF, Socorro S. Metformin and male reproduction: effects on Sertoli cell metabolism. British Journal of Pharmacology. 171: 1033-42. PMID 24261663 DOI: 10.1111/bph.12522  0.277
2017 Cabral Pinto MM, Marinho-Reis AP, Almeida A, Ordens CM, Silva MM, Freitas S, Simões MR, Moreira PI, Dinis PA, Diniz ML, Ferreira da Silva EA, Condesso de Melo MT. Human predisposition to cognitive impairment and its relation with environmental exposure to potentially toxic elements. Environmental Geochemistry and Health. PMID 28281140 DOI: 10.1007/s10653-017-9928-3  0.274
2022 Diniz A, Alves MG, Candeias E, Duarte AI, Moreira PI, Silva BM, Oliveira PF, Rato L. Type 2 Diabetes Induces a Pro-Oxidative Environment in Rat Epididymis by Disrupting SIRT1/PGC-1α/SIRT3 Pathway. International Journal of Molecular Sciences. 23. PMID 36012191 DOI: 10.3390/ijms23168912  0.274
2012 Vaz CV, Alves MG, Marques R, Moreira PI, Oliveira PF, Maia CJ, Socorro S. Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile. The International Journal of Biochemistry & Cell Biology. 44: 2077-84. PMID 22964025 DOI: 10.1016/j.biocel.2012.08.013  0.274
2021 Cardoso S, López IP, Piñeiro-Hermida S, Pichel JG, Moreira PI. IGF1R Deficiency Modulates Brain Signaling Pathways and Disturbs Mitochondria and Redox Homeostasis. Biomedicines. 9. PMID 33562061 DOI: 10.3390/biomedicines9020158  0.272
2013 Alves MG, Martins AD, Rato L, Moreira PI, Socorro S, Oliveira PF. Molecular mechanisms beyond glucose transport in diabetes-related male infertility. Biochimica Et Biophysica Acta. 1832: 626-35. PMID 23348098 DOI: 10.1016/j.bbadis.2013.01.011  0.272
2015 Alves MG, Martins AD, Moreira PI, Carvalho RA, Sousa M, Barros A, Silva J, Pinto S, Simões T, Oliveira PF. Metabolic fingerprints in testicular biopsies from type 1 diabetic patients. Cell and Tissue Research. PMID 26051285 DOI: 10.1007/S00441-015-2217-5  0.271
2013 Martins AD, Alves MG, Simões VL, Dias TR, Rato L, Moreira PI, Socorro S, Cavaco JE, Oliveira PF. Control of Sertoli cell metabolism by sex steroid hormones is mediated through modulation in glycolysis-related transporters and enzymes. Cell and Tissue Research. 354: 861-8. PMID 24057877 DOI: 10.1007/s00441-013-1722-7  0.268
2015 Monteiro-Cardoso VF, Castro M, Oliveira MM, Moreira PI, Peixoto F, Videira RA. Age-dependent biochemical dysfunction in skeletal muscle of triple-transgenic mouse model of Alzheimer's disease Current Alzheimer Research. 12: 100-115.  0.258
2007 Nunes E, Peixoto F, Louro T, Sena CM, Santos MS, Matafome P, Moreira PI, Seiça R. Soybean oil treatment impairs glucose-stimulated insulin secretion and changes fatty acid composition of normal and diabetic islets. Acta Diabetologica. 44: 121-30. PMID 17721750 DOI: 10.1007/s00592-007-0252-8  0.258
2022 Pereira AC, De Pascale J, Resende R, Cardoso S, Ferreira I, Neves BM, Carrascal MA, Zuzarte M, Madeira N, Morais S, Macedo A, do Carmo A, Moreira PI, Cruz MT, Pereira CF. ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system. Cellular and Molecular Life Sciences : Cmls. 79: 213. PMID 35344105 DOI: 10.1007/s00018-022-04211-7  0.257
2020 Gerardo B, Cabral Pinto M, Nogueira J, Pinto P, Almeida A, Pinto E, Marinho-Reis P, Diniz L, Moreira PI, Simões MR, Freitas S. Associations between Trace Elements and Cognitive Decline: An Exploratory 5-Year Follow-Up Study of an Elderly Cohort. International Journal of Environmental Research and Public Health. 17. PMID 32825289 DOI: 10.3390/ijerph17176051  0.255
2019 Cabral Pinto MMS, Marinho-Reis P, Almeida A, Pinto E, Neves O, Inácio M, Gerardo B, Freitas S, Simões MR, Dinis PA, Diniz L, Ferreira da Silva E, Moreira PI. Links between Cognitive Status and Trace Element Levels in Hair for an Environmentally Exposed Population: A Case Study in the Surroundings of the Estarreja Industrial Area. International Journal of Environmental Research and Public Health. 16. PMID 31752166 DOI: 10.3390/ijerph16224560  0.253
2017 Carvalho C, Moreira PI. Isolation of Rodent Brain Vessels. Bio-Protocol. 7: e2535. PMID 34541191 DOI: 10.21769/BioProtoc.2535  0.252
2013 Alves MG, Rato L, Carvalho RA, Moreira PI, Socorro S, Oliveira PF. Hormonal control of Sertoli cell metabolism regulates spermatogenesis. Cellular and Molecular Life Sciences : Cmls. 70: 777-93. PMID 23011766 DOI: 10.1007/S00018-012-1079-1  0.251
2016 Duarte AI, Sjögren M, Santos MS, Oliveira CR, Moreira PI, Björkqvist M. L23 Effects of peripheral (co-)administration of liraglutide and ghrelin in the R6/2 mouse brain function Journal of Neurology, Neurosurgery, and Psychiatry. 87. DOI: 10.1136/Jnnp-2016-314597.278  0.24
2023 Fernandes T, Domingues MR, Moreira PI, Pereira CF. A Perspective on the Link between Mitochondria-Associated Membranes (MAMs) and Lipid Droplets Metabolism in Neurodegenerative Diseases. Biology. 12. PMID 36979106 DOI: 10.3390/biology12030414  0.238
2024 Magro F, Fernandes S, Patita M, Arroja B, Lago P, Rosa I, de Sousa HT, Ministro P, Mocanu I, Vieira A, Castela J, Moleiro J, Roseira J, Cancela E, Sousa P, ... ... Moreira P, et al. The influence of subclinical active inflammation on IFX pharmacokinetic modeling and disease progression assessment: findings from a prospective real-world study in inflammatory bowel disease patients. Journal of Crohn's & Colitis. PMID 38243908 DOI: 10.1093/ecco-jcc/jjae014  0.234
2013 Alves MG, Neuhaus-Oliveira A, Moreira PI, Socorro S, Oliveira PF. Exposure to 2,4-dichlorophenoxyacetic acid alters glucose metabolism in immature rat Sertoli cells. Reproductive Toxicology (Elmsford, N.Y.). 38: 81-8. PMID 23538319 DOI: 10.1016/j.reprotox.2013.03.005  0.233
2015 González-Burgos E, Duarte AI, Carretero ME, Moreira PI, Gómez-Serranillos MP. Kaurane diterpenes as mitochondrial alterations preventive agents under experimental oxidative stress conditions. Pharmaceutical Biology. 1-7. PMID 26427521 DOI: 10.3109/13880209.2015.1072829  0.226
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Moreira PI, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886  0.225
2022 Ferreira H, Serranho P, Guimarães P, Trindade R, Martins J, Moreira PI, Ambrósio AF, Castelo-Branco M, Bernardes R. Stage-independent biomarkers for Alzheimer's disease from the living retina: an animal study. Scientific Reports. 12: 13667. PMID 35953633 DOI: 10.1038/s41598-022-18113-y  0.217
2020 Coimbra JRM, Baptista SJ, Dinis TCP, Silva MMC, Moreira PI, Santos AE, Salvador JAR. Combining Virtual Screening Protocol and In Vitro Evaluation towards the Discovery of BACE1 Inhibitors. Biomolecules. 10. PMID 32244832 DOI: 10.3390/biom10040535  0.203
2022 Roseira J, Santiago M, Estevinho MM, Moreira P, Alves C, Danese S, Peyrin-Biroulet L, Dignass A, Feakins R, Magro F. Impact of Crohn's Disease Therapies on Histology in Randomized Controlled Trials: Systematic Review With Meta-analysis. Inflammatory Bowel Diseases. PMID 36250778 DOI: 10.1093/ibd/izac203  0.196
2022 Guimarães P, Serranho P, Martins J, Moreira PI, Ambrósio AF, Castelo-Branco M, Bernardes R. Retinal Aging in 3× Tg-AD Mice Model of Alzheimer's Disease. Frontiers in Aging Neuroscience. 14: 832195. PMID 35783138 DOI: 10.3389/fnagi.2022.832195  0.191
2011 Moreira PI. Mark A. Smith – A Tribute Free Radicals and Antioxidants. 1: 4-5. DOI: 10.5530/Ax.2011.1.2  0.19
2021 Ferreira H, Martins J, Moreira PI, Ambrósio AF, Castelo-Branco M, Serranho P, Bernardes R. Longitudinal normative OCT retinal thickness data for wild-type mice, and characterization of changes in the 3×Tg-AD mice model of Alzheimer's disease. Aging. 13. PMID 33799308 DOI: 10.18632/aging.202916  0.188
2023 Magro F, Estevinho MM, Catalano G, Patita M, Arroja B, Lago P, Rosa I, Tavares de Sousa H, Ministro P, Mocanu I, Vieira A, Castela J, Moleiro J, Roseira J, Cancela E, ... ... Moreira P, et al. How many biomarker measurements are needed to predict prognosis in Crohn's disease patients under infliximab?-A prospective study. United European Gastroenterology Journal. PMID 37318072 DOI: 10.1002/ueg2.12420  0.161
2023 Coimbra JRM, Moreira PI, Santos AE, Salvador JAR. Therapeutic potential of glutaminyl cyclases: current status and emerging trends. Drug Discovery Today. 103644. PMID 37244566 DOI: 10.1016/j.drudis.2023.103644  0.148
2007 Moreira P, Filho PM, Silva EA, Weksler C, Drable SG, Tura BR, Fonseca Mda G, Cunha AB, Fischer RG. Effect of periodontal treatment on oral anticoagulation in patients with heart disease. Revista Portuguesa De Cardiologia : OrgãO Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : An Official Journal of the Portuguese Society of Cardiology. 26: 977-89. PMID 18232621  0.145
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Moreira PI, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.131
2023 Batista A, Guimarães P, Martins J, Moreira PI, Ambrósio AF, Castelo-Branco M, Serranho P, Bernardes R. Normative mice retinal thickness: 16-month longitudinal characterization of wild-type mice and changes in a model of Alzheimer's disease. Frontiers in Aging Neuroscience. 15: 1161847. PMID 37091517 DOI: 10.3389/fnagi.2023.1161847  0.126
2021 Magro F, Alves C, Santiago M, Ministro P, Lago P, Correia L, Gonçalves R, Carvalho D, Portela F, Dias CC, Dignass A, Danese S, Peyrin-Biroulet L, Estevinho MM, Moreira P, et al. Composite outcomes in observational studies of ulcerative colitis: A systematic review and meta-analysis. United European Gastroenterology Journal. PMID 34907660 DOI: 10.1002/ueg2.12183  0.05
2014 Burrows B, Moreira P, Murphy C, Sadi J, Walton DM. Scaphoid fractures: a higher order analysis of clinical tests and application of clinical reasoning strategies. Manual Therapy. 19: 372-8. PMID 24993797 DOI: 10.1016/j.math.2014.05.007  0.013
2023 Moreira PI. Rosalind Franklin Society Proudly Announces the 2022 Award Recipient for . Antioxidants & Redox Signaling. 39: 1. PMID 37459563 DOI: 10.1089/ars.2023.29202.rfs2022  0.01
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