Year |
Citation |
Score |
2020 |
Corcoran EB, McMullen JP, Lévesque F, Wismer MK, Naber JR. Use of Photon Equivalents as a Parameter for Scaling Photoredox Reactions in Flow: the translation of a photocatalytic C-N cross-coupling from lab scale to multikilogram scale. Angewandte Chemie (International Ed. in English). PMID 32243016 DOI: 10.1002/Anie.201915412 |
0.453 |
|
2019 |
Christensen M, Adedeji F, Grosser S, Zawatzky K, Ji Y, Liu J, Jurica JA, Naber JR, Hein JE. Development of an automated kinetic profiling system with online HPLC for reaction optimization Reaction Chemistry & Engineering. 4: 1555-1558. DOI: 10.1039/C9Re00086K |
0.437 |
|
2019 |
SalehiMarzijarani N, Snead DR, McMullen JP, Lévesque F, Weisel M, Varsolona RJ, Lam Y, Liu Z, Naber JR. One-Step Synthesis of 2‑Fluoroadenine UsingHydrogen Fluoride Pyridine in a Continuous Flow Operation Organic Process Research & Development. 23: 1522-1528. DOI: 10.1021/Acs.Oprd.9B00178 |
0.43 |
|
2019 |
Snead DR, Lévesque F, Morris WJ, Naber JR. An improved Balz-Schiemann reaction enabled by ionic liquids and continuous processing Tetrahedron. 75: 4261-4265. DOI: 10.1016/J.Tet.2019.05.020 |
0.376 |
|
2018 |
Thaisrivongs DA, Morris WJ, Tan L, Song ZJ, Lyons TW, Waldman JH, Naber JR, Chen W, Chen L, Zhang B, Yang J. A Next Generation Synthesis of BACE1 Inhibitor Verubecestat (MK-8931). Organic Letters. PMID 29481097 DOI: 10.1021/Acs.Orglett.8B00259 |
0.407 |
|
2018 |
Lévesque F, Rogus NJ, Spencer G, Grigorov P, McMullen JP, Thaisrivongs DA, Davies IW, Naber JR. Advancing Flow Chemistry Portability: A Simplified Approach to Scaling Up Flow Chemistry Organic Process Research & Development. 22: 1015-1021. DOI: 10.1021/Acs.Oprd.8B00063 |
0.37 |
|
2018 |
Thaisrivongs DA, Naber JR, Rogus NJ, Spencer G. Development of an Organometallic Flow Chemistry Reaction at Pilot-Plant Scale for the Manufacture of Verubecestat Organic Process Research & Development. 22: 403-408. DOI: 10.1021/Acs.Oprd.7B00385 |
0.372 |
|
2016 |
Thaisrivongs DA, Naber JR, McMullen JP. Using Flow To Outpace Fast Proton Transfer in an Organometallic Reaction for the Manufacture of Verubecestat (MK-8931) Organic Process Research & Development. 20: 1997-2004. DOI: 10.1021/Acs.Oprd.6B00247 |
0.409 |
|
2011 |
Noël T, Naber JR, Hartman RL, Mcmullen JP, Jensen KF, Buchwald SL. Palladium-catalyzed amination reactions in flow: Overcoming the challenges of clogging via acoustic irradiation Chemical Science. 2: 287-290. DOI: 10.1039/C0Sc00524J |
0.617 |
|
2010 |
Naber JR, Fors BP, Wu X, Gunn J, Buchwald SL. STILLE CROSS-COUPLING REACTIONS OF ARYL MESYLATES AND TOSYLATES USING A BIARYLPHOSPHINE BASED CATALYST SYSTEM. Heterocycles. 80: 1215-1226. PMID 23596345 DOI: 10.3987/Com-09-S(S)105 |
0.608 |
|
2010 |
Naber JR, Buchwald SL. Packed-bed reactors for continuous-flow C-N cross-coupling. Angewandte Chemie (International Ed. in English). 49: 9469-74. PMID 21038337 DOI: 10.1002/Anie.201004425 |
0.486 |
|
2010 |
Hartman RL, Naber JR, Buchwald SL, Jensen KF. Multistep microchemical synthesis enabled by microfluidic distillation. Angewandte Chemie (International Ed. in English). 49: 899-903. PMID 20025004 DOI: 10.1002/Anie.200904634 |
0.456 |
|
2010 |
Hartman RL, Naber JR, Zaborenko N, Buchwald SL, Jensen KF. Overcoming the challenges of solid bridging and constriction during Pd-catalyzed C-N bond formation in microreactors Organic Process Research and Development. 14: 1347-1357. DOI: 10.1021/Op100154D |
0.541 |
|
2008 |
Naber JR, Buchwald SL. Palladium-catalyzed Stille cross-coupling reaction of aryl chlorides using a pre-milled palladium acetate and XPhos catalyst system Advanced Synthesis and Catalysis. 350: 957-961. DOI: 10.1002/Adsc.200800032 |
0.605 |
|
2007 |
Hughes G, Devine PN, Naber JR, O'shea PD, Foster BS, McKay DJ, Volante RP. Diastereoselective reductive amination of aryl trifluoromethyl ketones and alpha-amino esters. Angewandte Chemie (International Ed. in English). 46: 1839-42. PMID 17450610 DOI: 10.1002/Anie.200603745 |
0.305 |
|
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