Year |
Citation |
Score |
2019 |
Gritsman K. FLT3-ITD gets by with a little help from PRMT1. Blood. 134: 498-500. PMID 31395582 DOI: 10.1182/Blood.2019001876 |
0.318 |
|
2019 |
Gurska LM, Ames K, Gritsman K. Signaling Pathways in Leukemic Stem Cells. Advances in Experimental Medicine and Biology. 1143: 1-39. PMID 31338813 DOI: 10.1007/978-981-13-7342-8_1 |
0.384 |
|
2019 |
Hemmati S, Sinclair T, Tong M, Bartholdy B, Okabe RO, Ames K, Ostrodka L, Haque T, Kaur I, Mills TS, Agarwal A, Pietras EM, Zhao JJ, Roberts TM, Gritsman K. PI3 kinase alpha and delta promote hematopoietic stem cell activation. Jci Insight. 5. PMID 31120863 DOI: 10.1172/Jci.Insight.125832 |
0.408 |
|
2018 |
Shah UA, Chung EY, Giricz O, Pradhan K, Kataoka K, Gordon-Mitchell S, Bhagat TD, Mai Y, Wei Y, Ishida E, Choudhary GS, Joseph A, Rice R, Gitego N, Parrish C, ... ... Gritsman K, et al. North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies. Blood. PMID 30104217 DOI: 10.1182/Blood-2018-01-824607 |
0.347 |
|
2018 |
Mitchell K, Barreyro L, Todorova TI, Taylor SJ, Antony-Debré I, Narayanagari SR, Carvajal LA, Leite J, Piperdi Z, Pendurti G, Mantzaris I, Paietta E, Verma A, Gritsman K, Steidl U. IL1RAP potentiates multiple oncogenic signaling pathways in AML. The Journal of Experimental Medicine. PMID 29773641 DOI: 10.1084/Jem.20180147 |
0.393 |
|
2018 |
Hemmati S, Sinclair T, Tong M, Bartholdy B, Okabe R, Ames K, Ostrodka L, Haque T, Kaur I, Agarwal A, Zhao J, Roberts T, Gritsman K. PI3Kinase Alpha and Delta Promote Hematopoietic Stem Activation Under Stress Blood. 132: 329-329. DOI: 10.1182/Blood-2018-99-114891 |
0.427 |
|
2017 |
Hemmati S, Haque T, Gritsman K. Inflammatory Signaling Pathways in Preleukemic and Leukemic Stem Cells. Frontiers in Oncology. 7: 265. PMID 29181334 DOI: 10.3389/Fonc.2017.00265 |
0.378 |
|
2017 |
Bhagat T, Chen S, Bartenstein M, Barlowe TS, von Ahrens D, Choudhary GS, Tivnan P, Amin E, Marcondes AM, Sanders MA, Hoogenboezem RM, Kambhampati S, Ramachandra N, Mantzaris I, Sukrithan V, ... ... Gritsman K, et al. Wnt/ß-catenin activation by epigenetically aberrant stroma drives myelodysplastic syndrome. Cancer Research. PMID 28684528 DOI: 10.1158/0008-5472.Can-17-0282 |
0.361 |
|
2017 |
Stanley RF, Piszczatowski RT, Bartholdy B, Mitchell K, McKimpson WM, Narayanagari S, Walter D, Todorova TI, Hirsch C, Makishima H, Will B, McMahon C, Gritsman K, Maciejewski JP, Kitsis RN, et al. A myeloid tumor suppressor role for NOL3. The Journal of Experimental Medicine. PMID 28232469 DOI: 10.1084/Jem.20162089 |
0.379 |
|
2016 |
Akula MK, Shi M, Jiang Z, Foster CE, Miao D, Li AS, Zhang X, Gavin RM, Forde SD, Germain G, Carpenter S, Rosadini CV, Gritsman K, Chae JJ, Hampton R, et al. Control of the innate immune response by the mevalonate pathway. Nature Immunology. PMID 27270400 DOI: 10.1038/Ni.3487 |
0.312 |
|
2016 |
Gritsman K, Hasserjian RP, Sinclair T, Weinstock DM, Will B, Steidl U, Ballen KK, Fathi AT, Verma A, Juric D, Amrein PC. Examination of Phosphoprotein Targets in Timed Samples from Patients with RAS-Mutated AML during Concurrent Treatment with Alpelisib and Binimetinib on the Phase Ib Clinical Trial CMEK162X2109 Blood. 128: 2749-2749. DOI: 10.1182/Blood.V128.22.2749.2749 |
0.38 |
|
2015 |
Yuzugullu H, Baitsch L, Von T, Steiner A, Tong H, Ni J, Clayton LK, Bronson R, Roberts TM, Gritsman K, Zhao JJ. A PI3K p110β-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis. Nature Communications. 6: 8501. PMID 26442967 DOI: 10.1038/Ncomms9501 |
0.403 |
|
2015 |
Pandolfi A, Stanley RF, Yu Y, Bartholdy B, Pendurti G, Gritsman K, Boultwood J, Chernoff J, Verma A, Steidl U. PAK1 is a therapeutic target in acute myeloid leukemia and myelodysplastic syndrome. Blood. PMID 26170031 DOI: 10.1182/Blood-2014-12-618801 |
0.365 |
|
2015 |
Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, Weigert O, Kopp N, Wu SC, Kim SS, Liu H, Tivey T, Christie AL, Elpek KG, Card J, ... Gritsman K, et al. Mutations in G protein β subunits promote transformation and kinase inhibitor resistance. Nature Medicine. 21: 71-5. PMID 25485910 DOI: 10.1038/Nm.3751 |
0.39 |
|
2015 |
Gritsman K, Kaur I, Sinclair T. The Class IA PI3 Kinase Isoforms Have Distinct but Overlapping Roles in Adult Hematopoiesis Blood. 126: 3587-3587. DOI: 10.1182/Blood.V126.23.3587.3587 |
0.393 |
|
2014 |
Gritsman K, Yuzugullu H, Von T, Yan H, Clayton L, Fritsch C, Maira SM, Hollingworth G, Choi C, Khandan T, Paktinat M, Okabe RO, Roberts TM, Zhao JJ. Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α. The Journal of Clinical Investigation. 124: 1794-809. PMID 24569456 DOI: 10.1172/Jci69927 |
0.358 |
|
2014 |
Yoda A, Adelmant G, Tamburini J, Chapuy B, Shindoh N, Yoda Y, Weigert O, Kopp N, Wu S, Kim SS, Liu H, Tivey T, Christie AL, Elpek KG, Card J, ... Gritsman K, et al. GNB1 Activating Mutations Promote Myeloid and Lymphoid Neoplasms Targetable By Combined PI3K/mTOR Inhibition Blood. 124: 3567-3567. DOI: 10.1182/Blood.V124.21.3567.3567 |
0.449 |
|
2014 |
Yuzugullu H, Baitsch L, Steiner A, Clayton LK, Gritsman K, Zhao JJ. Abstract 4775: PI3K-p110β is required for leukemic transformation and HSC depletion in the absence of Pten Cancer Research. 74: 4775-4775. DOI: 10.1158/1538-7445.Am2014-4775 |
0.421 |
|
2012 |
Gritsman K, Clayton L, Gilliland DG, Roberts TM, Zhao J. The p110alpha and p110delta Isoforms of PI3 Kinase Are Dispensable for Hematopoietic Stem Cell Self-Renewal but Have Redundant Roles in B Cell Differentiation. Blood. 120: 2322-2322. DOI: 10.1182/Blood.V120.21.2322.2322 |
0.401 |
|
2010 |
Kharas MG, Gritsman K. Akt: a double-edged sword for hematopoietic stem cells. Cell Cycle (Georgetown, Tex.). 9: 1223-4. PMID 20234178 DOI: 10.4161/Cc.9.7.11362 |
0.367 |
|
2010 |
Kharas MG, Okabe R, Ganis JJ, Gozo M, Khandan T, Paktinat M, Gilliland DG, Gritsman K. Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice. Blood. 115: 1406-15. PMID 20008787 DOI: 10.1182/Blood-2009-06-229443 |
0.429 |
|
2000 |
Gritsman K, Talbot WS, Schier AF. Nodal signaling patterns the organizer. Development (Cambridge, England). 127: 921-32. PMID 10662632 |
0.537 |
|
1999 |
Yan YT, Gritsman K, Ding J, Burdine RD, Corrales JD, Price SM, Talbot WS, Schier AF, Shen MM. Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation. Genes & Development. 13: 2527-37. PMID 10521397 DOI: 10.1101/Gad.13.19.2527 |
0.603 |
|
1999 |
Meno C, Gritsman K, Ohishi S, Ohfuji Y, Heckscher E, Mochida K, Shimono A, Kondoh H, Talbot WS, Robertson EJ, Schier AF, Hamada H. Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation. Molecular Cell. 4: 287-98. PMID 10518210 DOI: 10.1016/S1097-2765(00)80331-7 |
0.575 |
|
1999 |
Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, Schier AF. The EGF-CFC protein one-eyed pinhead is essential for nodal signaling. Cell. 97: 121-32. PMID 10199408 DOI: 10.1016/S0092-8674(00)80720-5 |
0.629 |
|
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