| Year |
Citation |
Score |
| 2015 |
Cheng Y, Brown J, Judd TC, Lopez P, Qian W, Powers TS, Chen JJ, Bartberger MD, Chen K, Dunn RT, Epstein O, Fremeau RT, Harried S, Hickman D, Hitchcock SA, ... ... White RD, et al. An Orally Available BACE1 Inhibitor That Affords Robust CNS Aβ Reduction without Cardiovascular Liabilities. Acs Medicinal Chemistry Letters. 6: 210-5. PMID 25699151 DOI: 10.1021/ml500458t |
0.453 |
|
| 2015 |
Chen JJ, Liu Q, Yuan C, Gore V, Lopez P, Ma V, Amegadzie A, Qian W, Judd TC, Minatti AE, Brown J, Cheng Y, Xue M, Zhong W, Dineen TA, ... ... White RD, et al. Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer's disease. Bioorganic & Medicinal Chemistry Letters. 25: 767-74. PMID 25613679 DOI: 10.1016/J.Bmcl.2014.12.092 |
0.423 |
|
| 2014 |
Epstein O, Bryan MC, Cheng AC, Derakhchan K, Dineen TA, Hickman D, Hua Z, Human JB, Kreiman C, Marx IE, Weiss MM, Wahl RC, Wen PH, Whittington DA, Wood S, ... ... White RD, et al. Lead optimization and modulation of hERG activity in a series of aminooxazoline xanthene β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. Journal of Medicinal Chemistry. 57: 9796-810. PMID 25389560 DOI: 10.1021/Jm501266W |
0.462 |
|
| 2014 |
Dineen TA, Chen K, Cheng AC, Derakhchan K, Epstein O, Esmay J, Hickman D, Kreiman CE, Marx IE, Wahl RC, Wen PH, Weiss MM, Whittington DA, Wood S, Fremeau RT, ... White RD, et al. Inhibitors of β-site amyloid precursor protein cleaving enzyme (BACE1): identification of (S)-7-(2-fluoropyridin-3-yl)-3-((3-methyloxetan-3-yl)ethynyl)-5'H-spiro[chromeno[2,3-b]pyridine-5,4'-oxazol]-2'-amine (AMG-8718). Journal of Medicinal Chemistry. 57: 9811-31. PMID 25363711 DOI: 10.1021/Jm5012676 |
0.476 |
|
| 2010 |
Tamaki K, Shotwell JB, White RD, Drutu I, Petsch DT, Nheu TV, He H, Hirokawa Y, Maruta H, Wood JL. ChemInform Abstract: Efficient Syntheses of Novel C2′-Alkylated (.+-.)-K252a Analogues. Cheminform. 32: no-no. DOI: 10.1002/chin.200138214 |
0.664 |
|
| 2008 |
Harmange JC, Weiss MM, Germain J, Polverino AJ, Borg G, Bready J, Chen D, Choquette D, Coxon A, DeMelfi T, DiPietro L, Doerr N, Estrada J, Flynn J, Graceffa RF, ... ... White RD, et al. Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation. Journal of Medicinal Chemistry. 51: 1649-67. PMID 18324761 DOI: 10.1021/jm701097z |
0.444 |
|
| 2007 |
Martin MW, Newcomb J, Nunes JJ, Bemis JE, McGowan DC, White RD, Buchanan JL, DiMauro EF, Boucher C, Faust T, Hsieh F, Huang X, Lee JH, Schneider S, Turci SM, et al. Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties. Bioorganic & Medicinal Chemistry Letters. 17: 2299-304. PMID 17276681 DOI: 10.1016/J.Bmcl.2007.01.048 |
0.302 |
|
| 2004 |
White RD, Keaney GF, Slown CD, Wood JL. Total synthesis of (+/-)-kalihinol C. Organic Letters. 6: 1123-6. PMID 15040738 DOI: 10.1021/Ol049918B |
0.652 |
|
| 2001 |
White RD, Wood JL. Progress toward the total synthesis of kalihinane diterpenoids. Organic Letters. 3: 1825-7. PMID 11405721 DOI: 10.1021/Ol015828K |
0.558 |
|
| 2001 |
Tamaki K, Shotwell JB, White RD, Drutu I, Petsch DT, Nheu TV, He H, Hirokawa Y, Maruta H, Wood JL. Efficient syntheses of novel C2'-alkylated (+/-)-K252a analogues. Organic Letters. 3: 1689-92. PMID 11405687 DOI: 10.1021/Ol015894M |
0.567 |
|
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