Richard Firtel - Publications

Affiliations: 
Biological Sciences University of California, San Diego, La Jolla, CA 

204 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Álvarez-González B, Zhang S, Gómez-González M, Meili R, Firtel RA, Lasheras JC, Del Álamo JC. Two-Layer Elastographic 3-D Traction Force Microscopy. Scientific Reports. 7: 39315. PMID 28074837 DOI: 10.1038/srep39315  0.56
2016 Bastounis E, Álvarez-González B, Del Álamo JC, Lasheras JC, Firtel RA. Cooperative Cell Motility during Tandem Locomotion of Amoeboid Cells. Molecular Biology of the Cell. PMID 26912787 DOI: 10.1091/mbc.E15-12-0836  0.96
2015 Álvarez-González B, Meili R, Bastounis E, Firtel RA, Lasheras JC, Del Álamo JC. Three-dimensional balance of cortical tension and axial contractility enables fast amoeboid migration. Biophysical Journal. 108: 821-32. PMID 25692587 DOI: 10.1016/j.bpj.2014.11.3478  0.96
2014 Alvarez-González B, Meili R, Firtel R, Bastounis E, Del Álamo JC, Lasheras JC. Cytoskeletal Mechanics Regulating Amoeboid Cell Locomotion. Applied Mechanics Reviews. 66. PMID 25328163 DOI: 10.1115/1.4026249  0.96
2014 Bastounis E, Meili R, Álvarez-González B, Francois J, del Álamo JC, Firtel RA, Lasheras JC. Both contractile axial and lateral traction force dynamics drive amoeboid cell motility. The Journal of Cell Biology. 204: 1045-61. PMID 24637328 DOI: 10.1083/jcb.201307106  0.96
2014 Sumita K, Yoshino H, Sasaki M, Majd N, Kahoud ER, Takahashi H, Takeuchi K, Kuroda T, Lee S, Charest PG, Takeda K, Asara JM, Firtel RA, Anastasiou D, Sasaki AT. Degradation of activated K-Ras orthologue via K-Ras-specific lysine residues is required for cytokinesis. The Journal of Biological Chemistry. 289: 3950-9. PMID 24338482 DOI: 10.1074/jbc.M113.531178  0.96
2014 Alvarez-Gonzalez B, Bastounis E, Meili R, Del Alamo JC, Firtel R, Lasheras JC. Closure to discussion of 'cytoskeletal mechanics regulating amoeboid cell locomotion' (2014, ASME Appl. Mech. Rev., 66(5), p. 055502) Applied Mechanics Reviews. 66. DOI: 10.1115/1.4027404  0.96
2013 del Álamo JC, Meili R, Álvarez-González B, Alonso-Latorre B, Bastounis E, Firtel R, Lasheras JC. Three-dimensional quantification of cellular traction forces and mechanosensing of thin substrata by fourier traction force microscopy. Plos One. 8: e69850. PMID 24023712 DOI: 10.1371/journal.pone.0069850  0.96
2013 Kölsch V, Shen Z, Lee S, Plak K, Lotfi P, Chang J, Charest PG, Romero JL, Jeon TJ, Kortholt A, Briggs SP, Firtel RA. Daydreamer, a Ras effector and GSK-3 substrate, is important for directional sensing and cell motility. Molecular Biology of the Cell. 24: 100-14. PMID 23135995 DOI: 10.1091/mbc.E12-04-0271  0.96
2012 Rappel WJ, Firtel RA. Adaptation in a eukaryotic pathway: combining experiments with modeling. Cell Cycle (Georgetown, Tex.). 11: 1051-2. PMID 22391206 DOI: 10.4161/cc.11.6.19715  0.96
2012 Kee YS, Ren Y, Dorfman D, Iijima M, Firtel R, Iglesias PA, Robinson DN. A mechanosensory system governs myosin II accumulation in dividing cells. Molecular Biology of the Cell. 23: 1510-23. PMID 22379107 DOI: 10.1091/mbc.E11-07-0601  0.96
2012 Takeda K, Shao D, Adler M, Charest PG, Loomis WF, Levine H, Groisman A, Rappel WJ, Firtel RA. Incoherent feedforward control governs adaptation of activated ras in a eukaryotic chemotaxis pathway. Science Signaling. 5: ra2. PMID 22215733 DOI: 10.1126/scisignal.2002413  0.96
2011 Alonso-Latorre B, Del Álamo JC, Meili R, Firtel RA, Lasheras JC. An Oscillatory Contractile Pole-Force Component Dominates the Traction Forces Exerted by Migrating Amoeboid Cells. Cellular and Molecular Bioengineering. 4: 603-615. PMID 22207880 DOI: 10.1007/s12195-011-0184-9  0.96
2011 Bastounis E, Meili R, Alonso-Latorre B, del Álamo JC, Lasheras JC, Firtel RA. The SCAR/WAVE complex is necessary for proper regulation of traction stresses during amoeboid motility. Molecular Biology of the Cell. 22: 3995-4003. PMID 21900496 DOI: 10.1091/mbc.E11-03-0278  0.96
2011 Hecht I, Skoge ML, Charest PG, Ben-Jacob E, Firtel RA, Loomis WF, Levine H, Rappel WJ. Activated membrane patches guide chemotactic cell motility. Plos Computational Biology. 7: e1002044. PMID 21738453 DOI: 10.1371/journal.pcbi.1002044  0.96
2011 Kicka S, Shen Z, Annesley SJ, Fisher PR, Lee S, Briggs S, Firtel RA. The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton. Molecular Biology of the Cell. 22: 2198-211. PMID 21551065 DOI: 10.1091/mbc.E10-12-0937  0.64
2010 Charest PG, Firtel RA. "TORCing" neutrophil chemotaxis. Developmental Cell. 19: 795-6. PMID 21145496 DOI: 10.1016/j.devcel.2010.11.017  0.96
2010 Charest PG, Shen Z, Lakoduk A, Sasaki AT, Briggs SP, Firtel RA. A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration. Developmental Cell. 18: 737-49. PMID 20493808 DOI: 10.1016/j.devcel.2010.03.017  0.96
2010 Lee S, Shen Z, Robinson DN, Briggs S, Firtel RA. Involvement of the cytoskeleton in controlling leading-edge function during chemotaxis. Molecular Biology of the Cell. 21: 1810-24. PMID 20375144 DOI: 10.1091/mbc.E10-01-0009  0.96
2010 Meili R, Alonso-Latorre B, del Alamo JC, Firtel RA, Lasheras JC. Myosin II is essential for the spatiotemporal organization of traction forces during cell motility. Molecular Biology of the Cell. 21: 405-17. PMID 19955212 DOI: 10.1091/mbc.E09-08-0703  0.96
2009 Alonso-Latorre B, Meili R, Bastounis E, Del Alamo JC, Firtel R, Lasheras JC. Distribution of traction forces associated with shape changes during amoeboid cell migration. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 3346-9. PMID 19964075 DOI: 10.1109/IEMBS.2009.5333191  0.96
2009 Sasaki AT, Firtel RA. Spatiotemporal regulation of Ras-GTPases during chemotaxis. Methods in Molecular Biology (Clifton, N.J.). 571: 333-48. PMID 19763978 DOI: 10.1007/978-1-60761-198-1_23  0.96
2009 Ren Y, Effler JC, Norstrom M, Luo T, Firtel RA, Iglesias PA, Rock RS, Robinson DN. Mechanosensing through cooperative interactions between myosin II and the actin crosslinker cortexillin I. Current Biology : Cb. 19: 1421-8. PMID 19646871 DOI: 10.1016/j.cub.2009.07.018  0.96
2009 Jeon TJ, Lee S, Weeks G, Firtel RA. Regulation of Dictyostelium morphogenesis by RapGAP3. Developmental Biology. 328: 210-20. PMID 19284976 DOI: 10.1016/j.ydbio.2009.01.016  0.96
2009 Para A, Krischke M, Merlot S, Shen Z, Oberholzer M, Lee S, Briggs S, Firtel RA. Dictyostelium Dock180-related RacGEFs regulate the actin cytoskeleton during cell motility. Molecular Biology of the Cell. 20: 699-707. PMID 19037099 DOI: 10.1091/mbc.E08-09-0899  0.96
2008 Zhang S, Charest PG, Firtel RA. Spatiotemporal regulation of Ras activity provides directional sensing. Current Biology : Cb. 18: 1587-93. PMID 18948008 DOI: 10.1016/j.cub.2008.08.069  0.96
2008 Du F, Edwards K, Shen Z, Sun B, De Lozanne A, Briggs S, Firtel RA. Regulation of contractile vacuole formation and activity in Dictyostelium. The Embo Journal. 27: 2064-76. PMID 18636095 DOI: 10.1038/emboj.2008.131  0.96
2008 Janetopoulos C, Firtel RA. Directional sensing during chemotaxis. Febs Letters. 582: 2075-85. PMID 18452713 DOI: 10.1016/j.febslet.2008.04.035  0.96
2008 Araki T, Langenick J, Gamper M, Firtel RA, Williams JG. Evidence that DIF-1 and hyper-osmotic stress activate a Dictyostelium STAT by inhibiting a specific protein tyrosine phosphatase. Development (Cambridge, England). 135: 1347-53. PMID 18305004 DOI: 10.1242/dev.009936  0.96
2008 Kölsch V, Charest PG, Firtel RA. The regulation of cell motility and chemotaxis by phospholipid signaling. Journal of Cell Science. 121: 551-9. PMID 18287584 DOI: 10.1242/jcs.023333  0.96
2007 Jeon TJ, Lee DJ, Lee S, Weeks G, Firtel RA. Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells. The Journal of Cell Biology. 179: 833-43. PMID 18039932 DOI: 10.1083/jcb.200705068  0.96
2007 Del Alamo JC, Meili R, Alonso-Latorre B, Rodríguez-Rodríguez J, Aliseda A, Firtel RA, Lasheras JC. Spatio-temporal analysis of eukaryotic cell motility by improved force cytometry. Proceedings of the National Academy of Sciences of the United States of America. 104: 13343-8. PMID 17684097 DOI: 10.1073/pnas.0705815104  0.96
2007 Sasaki AT, Janetopoulos C, Lee S, Charest PG, Takeda K, Sundheimer LW, Meili R, Devreotes PN, Firtel RA. G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility. The Journal of Cell Biology. 178: 185-91. PMID 17635933 DOI: 10.1083/jcb.200611138  0.96
2007 Jeon TJ, Lee DJ, Merlot S, Weeks G, Firtel RA. Rap1 controls cell adhesion and cell motility through the regulation of myosin II. The Journal of Cell Biology. 176: 1021-33. PMID 17371831 DOI: 10.1083/jcb.200607072  0.96
2007 Mendoza MC, Booth EO, Shaulsky G, Firtel RA. MEK1 and protein phosphatase 4 coordinate Dictyostelium development and chemotaxis. Molecular and Cellular Biology. 27: 3817-27. PMID 17353263 DOI: 10.1128/MCB.02194-06  0.96
2007 Takeda K, Sasaki AT, Ha H, Seung HA, Firtel RA. Role of phosphatidylinositol 3-kinases in chemotaxis in Dictyostelium. The Journal of Biological Chemistry. 282: 11874-84. PMID 17331950 DOI: 10.1074/jbc.M610984200  0.96
2007 Charest PG, Firtel RA. Big roles for small GTPases in the control of directed cell movement. The Biochemical Journal. 401: 377-90. PMID 17173542 DOI: 10.1042/BJ20061432  0.96
2006 Mendoza MC, Firtel RA. Assaying chemotaxis of Dictyostelium cells. Methods in Molecular Biology (Clifton, N.J.). 346: 393-405. PMID 16957303 DOI: 10.1385/1-59745-144-4:393  0.96
2006 Charest PG, Firtel RA. Feedback signaling controls leading-edge formation during chemotaxis. Current Opinion in Genetics & Development. 16: 339-47. PMID 16806895 DOI: 10.1016/j.gde.2006.06.016  0.96
2006 Sasaki AT, Firtel RA. Regulation of chemotaxis by the orchestrated activation of Ras, PI3K, and TOR. European Journal of Cell Biology. 85: 873-95. PMID 16740339 DOI: 10.1016/j.ejcb.2006.04.007  0.96
2006 Firtel R, Zernicka-Goetz M. Pattern formation and developmental mechanisms Current Opinion in Genetics and Development. 16: 331-332. DOI: 10.1016/j.gde.2006.06.014  0.96
2005 Sasaki AT, Firtel RA. Finding the way: directional sensing and cell polarization through Ras signalling. Novartis Foundation Symposium. 269: 73-87; discussion 87. PMID 16355536  0.96
2005 Mendoza MC, Du F, Iranfar N, Tang N, Ma H, Loomis WF, Firtel RA. Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects. Molecular and Cellular Biology. 25: 7839-53. PMID 16107728 DOI: 10.1128/MCB.25.17.7839-7853.2005  0.96
2005 Lee S, Comer FI, Sasaki A, McLeod IX, Duong Y, Okumura K, Yates JR, Parent CA, Firtel RA. TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium. Molecular Biology of the Cell. 16: 4572-83. PMID 16079174 DOI: 10.1091/mbc.E05-04-0342  0.96
2005 Meili R, Sasaki AT, Firtel RA. Rho Rocks PTEN. Nature Cell Biology. 7: 334-5. PMID 15803130 DOI: 10.1038/ncb0405-334  0.96
2005 Myers SA, Han JW, Lee Y, Firtel RA, Chung CY. A Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxis. Molecular Biology of the Cell. 16: 2191-206. PMID 15728724 DOI: 10.1091/mbc.E04-09-0844  0.96
2005 Sheetz M, Firtel R, Titus MA, Borisy G, Alberts A, Peter M, Harden N, Nelson WJ. Discussion Novartis Foundation Symposium. 269: 87-91.  0.96
2005 Alberts A, Borisy G, Chang F, Humphries M, Firtel R, Kaibuchi K, Lane B, Lane D, Nelson WJ, Sheetz M. Final general discussion Novartis Foundation Symposium. 269: 223-230.  0.96
2005 Firtel R, Alberts A, Nelson WJ, Mostov K, Lane D, Sheetz M, Takenawa T, Yap A. General discussion I Novartis Foundation Symposium. 269: 30-34.  0.96
2005 Sheetz M, Firtel R, Titus MA, Borisy G, Alberts A, Peter M, Harden N, Nelson WJ. Discussion Novartis Foundation Symposium. 269: 87-91.  0.96
2005 Vallee R, Drubin D, Borisy G, Firtel R, Gundersen G, Chang F, Sheetz M, Cai M, Alberts A, Peter M. Discussion Novartis Foundation Symposium. 269: 43-46.  0.96
2005 Sheetz M, Firtel R, Titus MA, Borisy G, Alberts A, Peter M, Harden N, Nelson WJ. Discussion Novartis Foundation Symposium. 269: 87-91.  0.96
2005 Vallee R, Drubin D, Borisy G, Firtel R, Gundersen G, Chang F, Sheetz M, Cai M, Alberts A, Peter M. Discussion Novartis Foundation Symposium. 269: 43-46.  0.96
2005 Vallee R, Drubin D, Borisy G, Firtel R, Gundersen G, Chang F, Sheetz M, Cai M, Alberts A, Peter M. Discussion Novartis Foundation Symposium. 269: 43-46.  0.96
2004 Sasaki AT, Chun C, Takeda K, Firtel RA. Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. The Journal of Cell Biology. 167: 505-18. PMID 15534002 DOI: 10.1083/jcb.200406177  0.96
2004 Lee S, Rivero F, Park KC, Huang E, Funamoto S, Firtel RA. Dictyostelium PAKc is required for proper chemotaxis. Molecular Biology of the Cell. 15: 5456-69. PMID 15483055 DOI: 10.1091/mbc.E04-04-0323  0.96
2004 Park KC, Rivero F, Meili R, Lee S, Apone F, Firtel RA. Rac regulation of chemotaxis and morphogenesis in Dictyostelium. The Embo Journal. 23: 4177-89. PMID 15470506 DOI: 10.1038/sj.emboj.7600368  0.96
2004 Kimmel AR, Firtel RA. Breaking symmetries: regulation of Dictyostelium development through chemoattractant and morphogen signal-response. Current Opinion in Genetics & Development. 14: 540-9. PMID 15380246 DOI: 10.1016/j.gde.2004.08.001  0.96
2004 Chisholm RL, Firtel RA. Insights into morphogenesis from a simple developmental system. Nature Reviews. Molecular Cell Biology. 5: 531-41. PMID 15232571 DOI: 10.1038/nrm1427  0.96
2003 Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. Cell migration: integrating signals from front to back. Science (New York, N.Y.). 302: 1704-9. PMID 14657486 DOI: 10.1126/science.1092053  0.96
2003 Aubry L, Lee S, Ravanel K, Firtel RA. The novel ankyrin-repeat containing kinase ARCK-1 acts as a suppressor of the Spalten signaling pathway during Dictyostelium development. Developmental Biology. 263: 308-22. PMID 14597204 DOI: 10.1016/j.ydbio.2003.07.012  0.96
2003 Sun B, Ma H, Firtel RA. Dictyostelium stress-activated protein kinase alpha, a novel stress-activated mitogen-activated protein kinase kinase kinase-like kinase, is important for the proper regulation of the cytoskeleton. Molecular Biology of the Cell. 14: 4526-40. PMID 14593072 DOI: 10.1091/mbc.E03-01-0039  0.96
2003 Merlot S, Firtel RA. Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways. Journal of Cell Science. 116: 3471-8. PMID 12893811 DOI: 10.1242/jcs.00703  0.96
2003 Meili R, Firtel RA. Two poles and a compass. Cell. 114: 153-6. PMID 12887916 DOI: 10.1016/S0092-8674(03)00553-1  0.96
2003 Merlot S, Meili R, Pagliarini DJ, Maehama T, Dixon JE, Firtel RA. A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. The Journal of Biological Chemistry. 278: 39866-73. PMID 12878591 DOI: 10.1074/jbc.M306318200  0.96
2003 Huang YE, Iijima M, Parent CA, Funamoto S, Firtel RA, Devreotes P. Receptor-mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells. Molecular Biology of the Cell. 14: 1913-22. PMID 12802064 DOI: 10.1091/mbc.E02-10-0703  0.96
2003 Sun B, Firtel RA. A regulator of G protein signaling-containing kinase is important for chemotaxis and multicellular development in dictyostelium. Molecular Biology of the Cell. 14: 1727-43. PMID 12686622 DOI: 10.1091/mbc.E02-08-0550  0.96
2003 Meili R, Firtel RA. Follow the leader. Developmental Cell. 4: 291-3. PMID 12636911 DOI: 10.1016/S1534-5807(03)00064-9  0.96
2003 Firtel RA, Meili R. The Role of PI3 Kinase in Directional Sensing during Chemotaxis in Dictyostelium, a Model for Chemotaxis of Neutrophils and Macrophages Handbook of Cell Signaling. 2: 217-223. DOI: 10.1016/B978-012124546-7/50518-0  0.56
2002 Chung CY, Firtel RA. Signaling pathways at the leading edge of chemotaxing cells. Journal of Muscle Research and Cell Motility. 23: 773-9. PMID 12952075 DOI: 10.1023/A:1024479728970  0.96
2002 Han YH, Chung CY, Wessels D, Stephens S, Titus MA, Soll DR, Firtel RA. Requirement of a vasodilator-stimulated phosphoprotein family member for cell adhesion, the formation of filopodia, and chemotaxis in dictyostelium. The Journal of Biological Chemistry. 277: 49877-87. PMID 12388544 DOI: 10.1074/jbc.M209107200  0.96
2002 Meili R, Firtel RA. Leading the way. Nature Cell Biology. 4: E171. PMID 12105427 DOI: 10.1038/ncb0702-e171  0.96
2002 Funamoto S, Meili R, Lee S, Parry L, Firtel RA. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell. 109: 611-23. PMID 12062104 DOI: 10.1016/S0092-8674(02)00755-9  0.96
2002 Sobko A, Ma H, Firtel RA. Regulated SUMOylation and ubiquitination of DdMEK1 is required for proper chemotaxis. Developmental Cell. 2: 745-56. PMID 12062087 DOI: 10.1016/S1534-5807(02)00186-7  0.96
2002 Firtel R, Kimmel A. The leading edge: PI3K is essential for macropinosome formation Trends in Cell Biology. 12: 11.  0.96
2001 Chung CY, Funamoto S, Firtel RA. Signaling pathways controlling cell polarity and chemotaxis. Trends in Biochemical Sciences. 26: 557-66. PMID 11551793 DOI: 10.1016/S0968-0004(01)01934-X  0.96
2001 Brown JM, Firtel RA. Functional and regulatory analysis of the dictyostelium G-box binding factor. Developmental Biology. 234: 521-34. PMID 11397018 DOI: 10.1006/dbio.2001.0276  0.96
2001 Mohanty S, Lee S, Yadava N, Dealy MJ, Johnson RS, Firtel RA. Regulated protein degradation controls PKA function and cell-type differentiation in Dictyostelium. Genes & Development. 15: 1435-48. PMID 11390363 DOI: 10.1101/gad.871101  0.96
2001 Chung CY, Potikyan G, Firtel RA. Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa. Molecular Cell. 7: 937-47. PMID 11389841 DOI: 10.1016/S1097-2765(01)00247-7  0.96
2001 Funamoto S, Milan K, Meili R, Firtel RA. Role of phosphatidylinositol 3' kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium. The Journal of Cell Biology. 153: 795-810. PMID 11352940 DOI: 10.1083/jcb.153.4.795  0.96
2001 Briscoe C, Moniakis J, Kim JY, Brown JM, Hereld D, Devreotes PN, Firtel RA. The phosphorylated C-terminus of cAR1 plays a role in cell-type-specific gene expression and STATa tyrosine phosphorylation. Developmental Biology. 233: 225-36. PMID 11319871 DOI: 10.1006/dbio.2001.0217  0.96
2001 Moniakis J, Funamoto S, Fukuzawa M, Meisenhelder J, Araki T, Abe T, Meili R, Hunter T, Williams J, Firtel RA. An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway. Genes & Development. 15: 687-98. PMID 11274054 DOI: 10.1101/gad.871001  0.96
2001 Early A, Gamper M, Moniakis J, Kim E, Hunter T, Williams JG, Firtel RA. Protein tyrosine phosphatase PTP1 negatively regulates Dictyostelium STATa and is required for proper cell-type proportioning. Developmental Biology. 232: 233-45. PMID 11254360 DOI: 10.1006/dbio.2001.0171  0.96
2001 Firtel RA. STATs as regulators of cell fate in Dictyostelium Trends in Genetics. 17: 314.  0.96
2000 Williams JG, Firtel RA. HAPPY days for the Dictyostelium genome project. Genome Research. 10: 1658-9. PMID 11076849 DOI: 10.1101/gr.166100  0.96
2000 Wang J, Hou L, Awrey D, Loomis WF, Firtel RA, Siu CH. The membrane glycoprotein gp150 is encoded by the lagC gene and mediates cell-cell adhesion by heterophilic binding during Dictyostelium development. Developmental Biology. 227: 734-45. PMID 11071787 DOI: 10.1006/dbio.2000.9881  0.96
2000 Firtel RA. Shedding light on phototaxis Trends in Genetics : Tig. 16: 440. PMID 11050327  0.96
2000 Nelson MK, Clark A, Abe T, Nomura A, Yadava N, Funair CJ, Jermyn KA, Mohanty S, Firtel RA, Williams JG. An F-Box/WD40 repeat-containing protein important for Dictyostelium cell-type proportioning, slug behaviour, and culmination. Developmental Biology. 224: 42-59. PMID 10898960 DOI: 10.1006/dbio.2000.9793  0.96
2000 Firtel RA, Meili R. Dictyostelium: a model for regulated cell movement during morphogenesis. Current Opinion in Genetics & Development. 10: 421-7. PMID 10889066 DOI: 10.1016/S0959-437X(00)00107-6  0.96
2000 Firtel RA, Chung CY. The molecular genetics of chemotaxis: sensing and responding to chemoattractant gradients. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 22: 603-15. PMID 10878573 DOI: 10.1002/1521-1878(200007)22:7<603::AID-BIES3>3.0.CO;2-#  0.96
2000 Meili R, Ellsworth C, Firtel RA. A novel Akt/PKB-related kinase is essential for morphogenesis in Dictyostelium. Current Biology : Cb. 10: 708-17. PMID 10873800 DOI: 10.1016/S0960-9822(00)00536-4  0.96
2000 Chung CY, Lee S, Briscoe C, Ellsworth C, Firtel RA. Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 5225-30. PMID 10805781 DOI: 10.1073/pnas.97.10.5225  0.96
2000 Brown JM, Firtel RA. Just the right size: cell counting in Dictyostelium. Trends in Genetics : Tig. 16: 191-3. PMID 10782107 DOI: 10.1016/S0168-9525(00)01977-6  0.96
2000 Chien S, Chung CY, Sukumaran S, Osborne N, Lee S, Ellsworth C, McNally JG, Firtel RA. The Dictyostelium LIM domain-containing protein LIM2 is essential for proper chemotaxis and morphogenesis. Molecular Biology of the Cell. 11: 1275-91. PMID 10749929  0.96
2000 Firtel RA, Ish-Horowicz D. Differentiation and gene regulation - A rich developmental stew: Editorial overview Current Opinion in Genetics and Development. 10: 469-470. DOI: 10.1016/S0959-437X(00)00114-3  0.96
2000 Firtel RA. Regulation of GSK3 Trends in Genetics. 16: 116.  0.96
1999 Mohanty S, Firtel RA. Control of spatial patterning and cell-type proportioning in Dictyostelium. Seminars in Cell & Developmental Biology. 10: 597-607. PMID 10706824 DOI: 10.1006/scdb.1999.0343  0.96
1999 Brown JM, Firtel RA. Regulation of cell-fate determination in Dictyostelium. Developmental Biology. 216: 426-41. PMID 10642783 DOI: 10.1006/dbio.1999.9485  0.96
1999 Aubry L, Firtel R. Integration of signaling networks that regulate Dictyostelium differentiation. Annual Review of Cell and Developmental Biology. 15: 469-517. PMID 10611970 DOI: 10.1146/annurev.cellbio.15.1.469  0.96
1999 Chung CY, Firtel RA. PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. The Journal of Cell Biology. 147: 559-76. PMID 10545500 DOI: 10.1083/jcb.147.3.559  0.96
1999 Lee S, Parent CA, Insall R, Firtel RA. A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium. Molecular Biology of the Cell. 10: 2829-45. PMID 10473630  0.96
1999 Mohanty S, Jermyn KA, Early A, Kawata T, Aubry L, Ceccarelli A, Schaap P, Williams JG, Firtel RA. Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis. Development (Cambridge, England). 126: 3391-405. PMID 10393118  0.96
1999 Gamper M, Kim E, Howard PK, Ma H, Hunter T, Firtel RA. Regulation of Dictyostelium protein-tyrosine phosphatase-3 (PTP3) through osmotic shock and stress stimulation and identification of pp130 as a PTP3 substrate. The Journal of Biological Chemistry. 274: 12129-38. PMID 10207040 DOI: 10.1074/jbc.274.17.12129  0.96
1999 Meili R, Ellsworth C, Lee S, Reddy TB, Ma H, Firtel RA. Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. The Embo Journal. 18: 2092-105. PMID 10205164 DOI: 10.1093/emboj/18.8.2092  0.96
1998 Chung CY, Reddy TB, Zhou K, Firtel RA. A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation. Genes & Development. 12: 3564-78. PMID 9832508  0.96
1998 Brown JM, Firtel RA. Phosphorelay signalling: new tricks for an ancient pathway. Current Biology : Cb. 8: R662-5. PMID 9740798  0.96
1998 Sukumaran S, Brown JM, Firtel RA, McNally JG. lagC-null and gbf-null cells define key steps in the morphogenesis of Dictyostelium mounds. Developmental Biology. 200: 16-26. PMID 9698452 DOI: 10.1006/dbio.1998.8934  0.96
1998 Araki T, Gamper M, Early A, Fukuzawa M, Abe T, Kawata T, Kim E, Firtel RA, Williams JG. Developmentally and spatially regulated activation of a Dictyostelium STAT protein by a serpentine receptor. The Embo Journal. 17: 4018-28. PMID 9670017 DOI: 10.1093/emboj/17.14.4018  0.96
1998 Yasukawa H, Mohanty S, Firtel RA. Identification and analysis of a gene that is essential for morphogenesis and prespore cell differentiation in Dictyostelium. Development (Cambridge, England). 125: 2565-76. PMID 9636072  0.96
1998 Aubry L, Firtel RA. Spalten, a protein containing Galpha-protein-like and PP2C domains, is essential for cell-type differentiation in Dictyostelium. Genes & Development. 12: 1525-38. PMID 9585512  0.96
1998 Cubitt AB, Reddy I, Lee S, McNally JG, Firtel RA. Coexpression of a constitutively active plasma membrane calcium pump with GFP identifies roles for intracellular calcium in controlling cell sorting during morphogenesis in Dictyostelium. Developmental Biology. 196: 77-94. PMID 9527882 DOI: 10.1006/dbio.1997.8831  0.96
1998 Han Z, Firtel RA. The homeobox-containing gene Wariai regulates anterior-posterior patterning and cell-type homeostasis in Dictyostelium. Development (Cambridge, England). 125: 313-25. PMID 9486804  0.96
1997 Clark A, Nomura A, Mohanty S, Firtel RA. A ubiquitin-conjugating enzyme is essential for developmental transitions in Dictyostelium. Molecular Biology of the Cell. 8: 1989-2002. PMID 9348538  0.96
1997 Maeda M, Firtel RA. Activation of the mitogen-activated protein kinase ERK2 by the chemoattractant folic acid in Dictyostelium. The Journal of Biological Chemistry. 272: 23690-5. PMID 9295311 DOI: 10.1074/jbc.272.38.23690  0.96
1997 Ma H, Gamper M, Parent C, Firtel RA. The Dictyostelium MAP kinase kinase DdMEK1 regulates chemotaxis and is essential for chemoattractant-mediated activation of guanylyl cyclase. The Embo Journal. 16: 4317-32. PMID 9250676 DOI: 10.1093/emboj/16.14.4317  0.96
1997 Mann SK, Brown JM, Briscoe C, Parent C, Pitt G, Devreotes PN, Firtel RA. Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium. Developmental Biology. 183: 208-21. PMID 9126295 DOI: 10.1006/dbio.1996.8499  0.96
1997 Buczynski G, Grove B, Nomura A, Kleve M, Bush J, Firtel RA, Cardelli J. Inactivation of two Dictyostelium discoideum genes, DdPIK1 and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, and actin cytoskeleton organization. The Journal of Cell Biology. 136: 1271-86. PMID 9087443 DOI: 10.1083/jcb.136.6.1271  0.96
1997 Lee S, Escalante R, Firtel RA. A Ras GAP is essential for cytokinesis and spatial patterning in Dictyostelium. Development (Cambridge, England). 124: 983-96. PMID 9056774  0.96
1997 Aubry L, Maeda M, Insall R, Devreotes PN, Firtel RA. The Dictyostelium mitogen-activated protein kinase ERK2 is regulated by Ras and cAMP-dependent protein kinase (PKA) and mediates PKA function. The Journal of Biological Chemistry. 272: 3883-6. PMID 9020088 DOI: 10.1074/jbc.272.7.3883  0.96
1997 Rietdorf J, Siegert F, Dharmawardhane S, Firtel RA, Weijer CJ. Analysis of cell movement and signalling during ring formation in an activated G alpha1 mutant of Dictyostelium discoideum that is defective in prestalk zone formation. Developmental Biology. 181: 79-90. PMID 9015266 DOI: 10.1006/dbio.1996.8447  0.96
1996 Firtel RA. Interacting signaling pathways controlling multicellular development in Dictyostelium. Current Opinion in Genetics & Development. 6: 545-54. PMID 8939724 DOI: 10.1016/S0959-437X(96)80082-7  0.96
1996 Maeda M, Aubry L, Insall R, Gaskins C, Devreotes PN, Firtel RA. Seven helix chemoattractant receptors transiently stimulate mitogen-activated protein kinase in Dictyostelium. Role of heterotrimeric G proteins. The Journal of Biological Chemistry. 271: 3351-4. PMID 8631932  0.96
1996 Gamper M, Howard PK, Hunter T, Firtel RA. Multiple roles of the novel protein tyrosine phosphatase PTP3 during Dictyostelium growth and development. Molecular and Cellular Biology. 16: 2431-44. PMID 8628311  0.96
1996 Hadwiger JA, Natarajan K, Firtel RA. Mutations in the Dictyostelium heterotrimeric G protein alpha subunit G alpha5 alter the kinetics of tip morphogenesis. Development (Cambridge, England). 122: 1215-24. PMID 8620848  0.96
1996 Gaskins C, Clark AM, Aubry L, Segall JE, Firtel RA. The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways. Genes & Development. 10: 118-28. PMID 8557190  0.96
1995 Cao JG, Firtel RA. Growth and developmental functions of a human immunodeficiency virus Tat- binding protein/26S protease subunit homolog from Dictyostelium discoideum Molecular and Cellular Biology. 15: 1725-1736. PMID 7862164  0.96
1995 Segall JE, Kuspa A, Shaulsky G, Ecke M, Maeda M, Gaskins C, Firtel RA, Loomis WF. A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium. The Journal of Cell Biology. 128: 405-13. PMID 7844154 DOI: 10.1083/jcb.128.3.405  0.96
1995 Briscoe C, Firtel RA. Intercellular signaling. A kinase for cell-fate determination? Current Biology : Cb. 5: 228-31. PMID 7780726 DOI: 10.1016/S0960-9822(95)00045-5  0.96
1995 Schnitzler GR, Briscoe C, Brown JM, Firtel RA. Serpentine cAMP receptors may act through a G protein-independent pathway to induce postaggregative development in Dictyostelium. Cell. 81: 737-45. PMID 7774015 DOI: 10.1016/0092-8674(95)90535-9  0.96
1995 Cubitt AB, Firtel RA, Fischer G, Jaffe LF, Miller AL. Patterns of free calcium in multicellular stages of Dictyostelium expressing jellyfish apoaequorin. Development (Cambridge, England). 121: 2291-301. PMID 7671796  0.96
1995 Firtel RA. Integration of signaling information in controlling cell-fate decisions in Dictyostelium Genes and Development. 9: 1427-1444. PMID 7601348  0.96
1995 Zhou K, Takegawa K, Emr SD, Firtel RA. A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: Biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development Molecular and Cellular Biology. 15: 5645-5656. PMID 7565716  0.96
1994 Carrel F, Dharmawardhane S, Clark AM, Powell-Coffman JA, Firtel RA. Spatial and temporal expression of the Dictyostelium discoideum G alpha protein subunit G alpha 2: expression of a dominant negative protein inhibits proper prestalk to stalk differentiation. Molecular Biology of the Cell. 5: 7-16. PMID 8186466  0.96
1994 Schnitzler GR, Fischer WH, Firtel RA. Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium Genes and Development. 8: 502-514. PMID 8125261  0.96
1994 Powell-Coffman JA, Schnitzler GR, Firtel RA. A GBF-binding site and a novel AT element define the minimal sequences sufficient to direct prespore-specific expression in Dictyostelium discoideum. Molecular and Cellular Biology. 14: 5840-9. PMID 8065317  0.96
1994 Powell-Coffman JA, Firtel RA. Characterization of a novel Dictyostelium discoideum prespore-specific gene, PspB, reveals conserved regulatory sequences. Development (Cambridge, England). 120: 1601-11. PMID 8050366  0.96
1994 Wu L, Gaskins C, Zhou K, Firtel RA, Devreotes PN. Cloning and targeted mutations of G alpha 7 and G alpha 8, two developmentally regulated G protein alpha-subunit genes in Dictyostelium. Molecular Biology of the Cell. 5: 691-702. PMID 7949425  0.96
1994 Hadwiger JA, Lee S, Firtel RA. The G alpha subunit G alpha 4 couples to pterin receptors and identifies a signaling pathway that is essential for multicellular development in Dictyostelium. Proceedings of the National Academy of Sciences of the United States of America. 91: 10566-70. PMID 7937994  0.96
1994 Mann SKO, Richardson DL, Lee S, Kimmel AR, Firtel RA. Expression of cAMP-dependent protein kinase in prespore cells is sufficient to induce spore cell differentiation in Dictyostelium Proceedings of the National Academy of Sciences of the United States of America. 91: 10561-10565. PMID 7937993 DOI: 10.1073/pnas.91.22.10561  0.96
1994 Gaskins C, Maeda M, Firtel RA. Identification and functional analysis of a developmentally regulated extracellular signal-regulated kinase gene in Dictyostelium discoideum. Molecular and Cellular Biology. 14: 6996-7012. PMID 7935416  0.96
1994 Dynes JL, Clark AM, Shaulsky G, Kuspa A, Loomis WF, Firtel RA. LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium Genes and Development. 8: 948-958. PMID 7926779  0.96
1994 Dharmawardhane S, Cubitt AB, Clark AM, Firtel RA. Regulatory role of the Gα1 subunit in controlling cellular morphogenesis in Dictyostelium Development. 120: 3549-3561. PMID 7821221  0.96
1994 Hori R, Firtel RA. Identification and characterization of multiple A/T-rich cis-acting elements that control expression from Dictyostelium actin promoters: The Dictyostelium actin upstream activating sequence confers growth phase expression and has enhancer-like properties Nucleic Acids Research. 22: 5099-5111. PMID 7800506  0.96
1994 Howard PK, Gamper M, Hunter T, Firtel RA. Regulation by protein-tyrosine phosphatase PTP2 is distinct from that by PTP1 during Dictyostelium growth and development Molecular and Cellular Biology. 14: 5154-5164. PMID 7518559  0.96
1993 Cubitt AB, Dharmawardhane S, Firtel RA. Developmentally regulated changes in 1,2-diacylglycerol in Dictyostelium. Regulation by light and G proteins Journal of Biological Chemistry. 268: 17431-17439. PMID 8394342  0.96
1993 Schaap P, Van Ments-Cohen M, Soede RDM, Brandt R, Firtel RA, Dostmann W, Genieser HG, Jastorff B, Van Haastert PJM. Cell-permeable non-hydrolyzable cAMP derivatives as tools for analysis of signaling pathways controlling gene regulation in Dictyostelium Journal of Biological Chemistry. 268: 6323-6331. PMID 8384208  0.96
1993 Schatzle J, Bush J, Dharmawardhane S, Firtel RA, Gomer RH, Cardelli J. Characterization of the signal transduction pathways and cis-acting DNA sequence responsible for the transcriptional induction during growth and development of the lysosomal α-mannosidase gene in Dictyostelium discoideum Journal of Biological Chemistry. 268: 19632-19639. PMID 8366107  0.96
1993 Mann SKO, Firtel RA. cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development Development. 119: 135-146. PMID 8275851  0.96
1993 Howard PK, Sefton BM, Firtel RA. Tyrosine phosphorylation of actin in Dictyostelium associated with cell-shape changes. Science (New York, N.Y.). 259: 241-4. PMID 7678470  0.96
1993 Powell-Coffman JA, Firtel RA. Cellular dedifferentiation and spore germination in dictyostellum may utilize similar regulatory pathways Bioessays. 15: 131-133.  0.96
1992 Hadwiger JA, Firtel RA. Analysis of G alpha 4, a G-protein subunit required for multicellular development in Dictyostelium. Genes & Development. 6: 38-49. PMID 1730409  0.96
1992 Stober-Grasser U, Brydolf B, Bin X, Grasser F, Firtel RA, Lipsick JS. The myb DNA-binding domain is highly conserved in Dictyostelium discoideum Oncogene. 7: 589-596. PMID 1549373  0.96
1992 Kikkawa U, Mann SKO, Firtel RA, Hunter T. Molecular cloning of casein kinase II α subunit from Dictyostelium discoideum and its expression in the life cycle Molecular and Cellular Biology. 12: 5711-5723. PMID 1448100  0.96
1992 Howard PK, Sefton BM, Firtel RA. Analysis of a spatially regulated phosphotyrosine phosphatase identifies tyrosine phosphorylation as a key regulatory pathway in Dictyostelium. Cell. 71: 637-47. PMID 1423620 DOI: 10.1016/0092-8674(92)90597-6  0.96
1992 Okaichi K, Cubitt AB, Pitt GS, Firtel RA. Amino acid substitutions in the Dictyostelium Gα subunit Gα2 produce dominant negative phenotypes and inhibit the activation of adenylyl cyclase, guanylyl cyclase, and phospholipase C Molecular Biology of the Cell. 3: 735-747. PMID 1355376  0.96
1992 Cubitt AB, Carrel F, Dharmawardhane S, Gaskins C, Hadwiger J, Howard P, Mann SK, Okaichi K, Zhou K, Firtel RA. Molecular genetic analysis of signal transduction pathways controlling multicellular development in Dictyostelium. Cold Spring Harbor Symposia On Quantitative Biology. 57: 177-92. PMID 1339658  0.96
1992 Mann SKO, Yonemoto WM, Taylor SS, Firtel RA. DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase Proceedings of the National Academy of Sciences of the United States of America. 89: 10701-10705. PMID 1332055 DOI: 10.1073/pnas.89.22.10701  0.96
1992 Ceccarelli A, Mahbubani HJ, Insall R, Schnitzler G, Firtel RA, Williams JG. A G-rich sequence element common to Dictyostelium genes which differ radically in their patterns of expression Developmental Biology. 152: 188-193. PMID 1321061 DOI: 10.1016/0012-1606(92)90169-H  0.96
1992 Powell JA, Galindo J, Firtel RA. A negative transcriptional control region of a developmentally-regulated gene co-localizes with the origin of replication of an endogenous plasmid in Dictyostelium Nucleic Acids Research. 20: 2795-2802. PMID 1319575 DOI: 10.1093/nar/20.11.2795  0.96
1992 Cubitt AB, Firtel RA. Characterization of phospholipase activity in Dictyostelium discoideum. Identification of a Ca2+-dependent polyphosphoinositidase-specific phospholipase C Biochemical Journal. 283: 371-378. PMID 1315514  0.96
1992 Keith Esch R, Howard PK, Firtel RA. Regulation of the dictyostelium camp-induced, prestalk-specific ddrasD gene: Identification of cis-acting elements Nucleic Acids Research. 20: 1325. DOI: 10.1093/nar/20.6.1325  0.96
1991 Hadwiger JA, Wilkie TM, Strathmann M, Firtel RA. Identification of Dictyostelium G alpha genes expressed during multicellular development. Proceedings of the National Academy of Sciences of the United States of America. 88: 8213-7. PMID 1910174  0.96
1991 Mann SKO, Firtel RA. A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium Mechanisms of Development. 35: 89-101. PMID 1836954 DOI: 10.1016/0925-4773(91)90060-J  0.96
1991 Esch RK, Firtel RA. cAMP and cell sorting control the spatial expression of a developmentally essential cell-type-specific ras gene in Dictyostelium Genes and Development. 5: 9-21. PMID 1703508  0.96
1991 Kumagai A, Hadwiger JA, Pupillo M, Firtel RA. Molecular genetic analysis of two G alpha protein subunits in Dictyostelium. The Journal of Biological Chemistry. 266: 1220-8. PMID 1670774  0.96
1991 Kimmel AR, Firtel RA. cAMP signal transduction pathways regulating development of Dictyostelium discoideum Current Opinion in Genetics and Development. 1: 383-390. PMID 1668648 DOI: 10.1016/S0959-437X(05)80304-1  0.96
1991 Haberstroh L, Galindo J, Firtel RA. Developmental and spatial regulation of a Dictyostelium prespore gene: cis-acting elements and a cAMP-induced, developmentally regulated DNA binding activity Development. 113: 947-958. PMID 1668278  0.96
1991 Firtel RA. Signal transduction pathways controlling multicellular development in Dictyostelium Trends in Genetics. 7: 381-388. PMID 1668191 DOI: 10.1016/0168-9525(91)90260-W  0.96
1991 Gomer RH, Yuen IS, Firtel RA. A secreted 80×103 Mr protein mediates sensing of cell density and the onset of development in Dictyostelium Development. 112: 269-278. PMID 1663029  0.96
1991 Firtel RA. Putting the G in development Current Biology. 1: 91-93. DOI: 10.1016/0960-9822(91)90287-7  0.96
1991 Blackburn E, Firtel RA, Shapiro L. Molecular genetics of simple developmental systems Current Opinion in Genetics and Development. 1: 305-306.  0.96
1990 Haberstroh L, Firtel RA. A spatial gradient of expression of a cAMP-regulated prespore cell-type gene in Dictyostelium Genes and Development. 4: 596-612. PMID 2163344  0.96
1990 Hjorth AL, Pears C, Williams JG, Firtel RA. A developmentally regulated trans-acting factor recognizes dissimilar G/C-rich elements controlling a class of cAMP-inducible Dictyostelium genes Genes and Development. 4: 419-432. PMID 2159939  0.96
1990 Firtel RA, Chapman AL. A role for cAMP-dependent protein kinase A in early Dictyostelium development. Genes & Development. 4: 18-28. PMID 1968413  0.96
1989 Rubino S, Mann SKO, Hori RT, Pinko C, Firtel RA. Molecular analysis of a developmentally regulated gene required for dictyostelium aggregation Developmental Biology. 131: 27-36. PMID 2909407 DOI: 10.1016/S0012-1606(89)80035-1  0.96
1989 Dynes JL, Firtel RA. Molecular complementation of a genetic marker in Dictyostelium using a genomic DNA library Proceedings of the National Academy of Sciences of the United States of America. 86: 7966-7970. PMID 2813371  0.96
1989 Armstrong DJ, Firtel RA. Cytokinin oxidase activity in the cellular slime mold, Dictyostelium discoideum Developmental Biology. 136: 491-499. PMID 2555236 DOI: 10.1016/0012-1606(89)90274-1  0.96
1989 Van Lookeren Campagne MM, Aerts RJ, Spek W, Firtel RA, Schaap P. Cyclic-AMP-induced elevation of intracellular pH precedes, but does not mediate, the induction of prespore differentiation in Dictyostelium discoideum Development. 105: 401-406. PMID 2553386  0.96
1989 Firtel RA, van Haastert PJM, Kimmel AR, Devreotes PN. G protein linked signal transduction pathways in development: Dictyostelium as an experimental system Cell. 58: 235-239. PMID 2546676 DOI: 10.1016/0092-8674(89)90837-4  0.96
1989 Hjorth AL, Khanna NC, Firtel RA. A trans-acting factor required for cAMP-induced gene expression in Dictyostelium is regulated developmentally and induced by cAMP Genes & Development. 3: 747-759. PMID 2545528  0.96
1989 Kumagai A, Pupillo M, Gundersen R, Miake-Lye R, Devreotes PN, Firtel RA. Regulation and function of Gα protein subunits in Dictyostelium Cell. 57: 265-275. PMID 2539262 DOI: 10.1016/0092-8674(89)90964-1  0.96
1989 Mann SK, Firtel RA. Two-phase regulatory pathway controls cAMP receptor-mediated expression of early genes in Dictyostelium Proceedings of the National Academy of Sciences of the United States of America. 86: 1924-1928. PMID 2538821  0.96
1989 Pupillo M, Kumagai A, Pitt GS, Firtel RA, Devreotes PN. Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium Proceedings of the National Academy of Sciences of the United States of America. 86: 4892-4896. PMID 2500658  0.96
1988 Ahem KG, Howard PK, Firtel RA. Identification of regions essential for extrachromosomal replication and maintenance of an endogenous plasmid in Diclyosrelium Nucleic Acids Research. 16: 6825-6837. PMID 3405751 DOI: 10.1093/nar/16.14.6825  0.96
1988 Kumagai A, Mann SKO, Pupillo M, Pitt G, Devreotes PN, Firtel RA. A molecular analysis of G proteins and control of early gene expression by the cell-surface cAMP receptor in Dictyostelium Cold Spring Harbor Symposia On Quantitative Biology. 53: 675-685. PMID 3151182  0.96
1988 Pupillo M, Klein P, Vaughan R, Pitt G, Lilly P, Sun T, Devreotes P, Kumagai A, Firtel R. cAMP receptor and G-protein interactions control development in Dictyostelium Cold Spring Harbor Symposia On Quantitative Biology. 53: 657-665. PMID 3151181  0.96
1988 Hjorth A, Datta S, Khanna NC, Firtel RA. Analysis of cis and trans elements involved in cAMP-inducible gene expression in Dictyostelium discoideum Developmental Genetics. 9: 435-454. PMID 2907423  0.96
1988 Datta S, Firtel RA. An 80-bp cis-acting regulatory region controls cAMP and development regulation of a prestalk gene in Dictyostelium Genes & Development. 2: 294-304. PMID 2897942  0.96
1988 Mann SKO, Pinko C, Firtel RA. Control of early gene expression in Dictyostelium Developmental Genetics. 9: 337-350. PMID 2854022  0.96
1988 Mann SKO, Pinko C, Firtel RA. Regulation of Dictyostelium early gene expression in cAMP bypass mutants Developmental Biology. 130: 406-410. PMID 2846389 DOI: 10.1016/0012-1606(88)90447-2  0.96
1988 Mann SKO, Pinko C, Firtel RA. cAMP regulation of early gene expression in signal transduction mutants of Dictyostelium Developmental Biology. 130: 294-303. PMID 2846388 DOI: 10.1016/0012-1606(88)90435-6  0.96
1988 Europe-Finner GN, Ludérus ME, Small NV, Van Driel R, Reymond CD, Firtel RA, Newell PC. Mutant ras gene induces elevated levels of inositol tris- and hexakisphosphates in Dictyostelium Journal of Cell Science. 89: Pt 1/-. PMID 2843553  0.96
1988 Howard PK, Ahern KG, Firtel RA. Establishment of a transient expression system for Dictyostelium discoideum Nucleic Acids Research. 16: 2613-2623. DOI: 10.1093/nar/16.6.2613  0.96
1987 Nellen W, Datta S, Reymond C, Sivertsen A, Mann S, Crowley T, Firtel RA. Chapter 4 Molecular Biology in Dictyostelium: Tools and Applications Methods in Cell Biology. 28: 67-100. PMID 3600419 DOI: 10.1016/S0091-679X(08)61637-4  0.96
1987 Van Haastert PJ, Kesbeke F, Reymond CD, Firtel RA, Luderus E, Van Driel R. Aberrant transmembrane signal transduction in Dictyostelium cells expressing a mutated ras gene Proceedings of the National Academy of Sciences of the United States of America. 84: 4905-4909. PMID 2885843  0.96
1975 Jacobson A, Firtel R, Lodish HF. The synthesis of messenger RNA in the cellular slime mold Dictyosteilum discoideum. Brookhaven Symposia in Biology. 307-19. PMID 1238151  0.96
1974 Jacobson A, Firtel RA, Lodish HF. Synthesis of messenger and ribosomal RNA precursors in isolated nuclei of the cellular slime mold Dictyostelium discoideum. Journal of Molecular Biology. 82: 213-30. PMID 4856245  0.96
1974 Lodish HF, Jacobson A, Firtel R, Alton T, Tuchman J. Synthesis of messenger RNA and chromosome structure in the cellular slime mold. Proceedings of the National Academy of Sciences of the United States of America. 71: 5103-8. PMID 4531041  0.96
1974 Lodish HF, Firtel RA, Jacobson A. Transcription and structure of the genome of the cellular slime mold Dictyostelium discoideum. Cold Spring Harbor Symposia On Quantitative Biology. 38: 899-914. PMID 4524794  0.96
1974 Firtel RA, Jacobson A, Tuchman J, Lodish HF. Gene activity during development of the cellular slime mold Dictyostelium discoideum. Genetics. 78: 355-72. PMID 4474971  0.96
1974 Verma IM, Firtel RA, Lodish HF, Baltimore D. Synthesis of DNA complementary to cellular slime mold messenger RNA by reverse transcriptase. Biochemistry. 13: 3917-22. PMID 4137959  0.96
1973 Firtel RA, Baxter L, Lodish HF. Actinomycin D and the regulation of enzyme biosynthesis during development of Dictyostelium discoideum. Journal of Molecular Biology. 79: 315-27. PMID 4796770  0.96
1973 Firtel RA, Lodish HF. A small nuclear precursor of messenger RNA in the cellular slime mold Dictyostelium discoideum. Journal of Molecular Biology. 79: 295-314. PMID 4796769  0.96
1972 Firtel RA, Jacobson A, Lodish HF. Isolation and hybridization kinetics of messenger RNA from Dictyostelium discoideum. Nature: New Biology. 239: 225-8. PMID 4507801  0.96
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