Chenghua Gu - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
Nervous and Vascular System Development

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Wood CAP, Zhang J, Aydin D, Xu Y, Andreone BJ, Langen UH, Dror RO, Gu C, Feng L. Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A. Nature. PMID 34349262 DOI: 10.1038/s41586-021-03782-y  1
2020 Andaloussi Mäe M, He L, Nordling S, Vazquez-Liebanas E, Nahar K, Jung B, Li X, Tan BC, Foo JC, Cazenave Gassiot A, Wenk M, Zarb Y, Lavina B, Quaggin SE, Jeansson M, ... Gu C, et al. Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss. Circulation Research. PMID 33375813 DOI: 10.1161/CIRCRESAHA.120.317473  0.01
2020 Clark AR, Randall EC, Lopez BGC, Regan MS, Agar JN, Andreone BJ, Gu C, Agar NYR. Spatial Distribution of Transcytosis Relevant Phospholipids in Response to Omega-3 Dietary Deprivation. Acs Chemical Biology. PMID 33315366 DOI: 10.1021/acschembio.0c00779  1
2020 Kaplan L, Chow BW, Gu C. Neuronal regulation of the blood-brain barrier and neurovascular coupling. Nature Reviews. Neuroscience. PMID 32636528 DOI: 10.1038/S41583-020-0322-2  1
2020 Granger AJ, Wang W, Robertson K, El-Rifai M, Zanello AF, Bistrong K, Saunders A, Chow BW, Nuñez V, Turrero García M, Harwell CC, Gu C, Sabatini BL. Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target-and brain-region specific manner. Elife. 9. PMID 32613945 DOI: 10.7554/Elife.57749  1
2020 Chow BW, Nuñez V, Kaplan L, Granger AJ, Bistrong K, Zucker HL, Kumar P, Sabatini BL, Gu C. Caveolae in CNS arterioles mediate neurovascular coupling. Nature. PMID 32076269 DOI: 10.1038/S41586-020-2026-1  1
2020 Granger AJ, Wang W, Robertson K, El-Rifai M, Zanello AF, Bistrong K, Saunders A, Chow BW, Nuñez V, García MT, Harwell CC, Gu C, Sabatini BL. Author response: Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner Elife. DOI: 10.7554/Elife.57749.Sa2  1
2019 O'Brown NM, Megason SG, Gu C. Suppression of transcytosis regulates zebrafish blood-brain barrier function. Elife. 8. PMID 31429822 DOI: 10.7554/Elife.47326  0.01
2019 Langen UH, Ayloo S, Gu C. Development and Cell Biology of the Blood-Brain Barrier. Annual Review of Cell and Developmental Biology. PMID 31299172 DOI: 10.1146/annurev-cellbio-100617-062608  0.01
2019 Ayloo S, Gu C. Transcytosis at the blood-brain barrier. Current Opinion in Neurobiology. 57: 32-38. PMID 30708291 DOI: 10.1016/j.conb.2018.12.014  0.01
2019 Gu C, Betsholtz C. Decision letter: Hippocampal neural stem cells facilitate access from circulation via apical cytoplasmic processes Elife. DOI: 10.7554/Elife.52134.Sa1  0.01
2019 O'Brown NM, Megason SG, Gu C. Author response: Suppression of transcytosis regulates zebrafish blood-brain barrier function Elife. DOI: 10.7554/Elife.47326.036  0.01
2018 Sadeghian H, Lacoste B, Qin T, Toussay X, Rosa R, Oka F, Chung DY, Takizawa T, Gu C, Ayata C. Spreading depolarizations trigger caveolin-1-dependent endothelial transcytosis. Annals of Neurology. PMID 30014540 DOI: 10.1002/Ana.25298  1
2018 O'Brown NM, Pfau SJ, Gu C. Bridging barriers: a comparative look at the blood-brain barrier across organisms. Genes & Development. 32: 466-478. PMID 29692355 DOI: 10.1101/gad.309823.117  0.01
2017 Almasi S, Ben-Zvi A, Lacoste B, Gu C, Miller EL, Xu X. Joint volumetric extraction and enhancement of vasculature from low-SNR 3-D fluorescence microscopy images. Pattern Recognition. 63: 710-718. PMID 28566796 DOI: 10.1016/J.Patcog.2016.09.031  1
2017 Andreone BJ, Chow BW, Tata A, Lacoste B, Ben-Zvi A, Bullock K, Deik AA, Ginty DD, Clish CB, Gu C. Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis. Neuron. PMID 28416077 DOI: 10.1016/J.Neuron.2017.03.043  1
2017 Chow BW, Gu C. Gradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation. Neuron. 93: 1325-1333.e3. PMID 28334606 DOI: 10.1016/J.Neuron.2017.02.043  1
2016 Bosetti F, Galis ZS, Bynoe MS, Charette M, Cipolla MJ, Del Zoppo GJ, Gould D, Hatsukami TS, Jones TL, Koenig JI, Lutty GA, Maric-Bilkan C, Stevens T, Tolunay HE, Koroshetz W, et al. "Small Blood Vessels: Big Health Problems?": Scientific Recommendations of the National Institutes of Health Workshop. Journal of the American Heart Association. 5. PMID 27815267 DOI: 10.1161/Jaha.116.004389  0.01
2016 Kur E, Kim J, Tata A, Comin CH, Harrington KI, Costa LD, Bentley K, Gu C. Temporal modulation of collective cell behavior controls vascular network topology. Elife. 5. PMID 26910011 DOI: 10.7554/Elife.13212  1
2016 Kur E, Kim J, Tata A, Comin CH, Harrington KI, Costa LdF, Bentley K, Gu C. Author response: Temporal modulation of collective cell behavior controls vascular network topology Elife. DOI: 10.7554/Elife.13212.023  1
2015 Chow BW, Gu C. The Molecular Constituents of the Blood-Brain Barrier. Trends in Neurosciences. 38: 598-608. PMID 26442694 DOI: 10.1016/J.Tins.2015.08.003  1
2015 Lacoste B, Gu C. Control of cerebrovascular patterning by neural activity during postnatal development. Mechanisms of Development. PMID 26116138 DOI: 10.1016/J.Mod.2015.06.003  1
2015 Andreone BJ, Lacoste B, Gu C. Neuronal and Vascular Interactions. Annual Review of Neuroscience. 38: 25-46. PMID 25782970 DOI: 10.1146/Annurev-Neuro-071714-033835  1
2015 Keskin D, Kim J, Cooke VG, Wu CC, Sugimoto H, Gu C, De Palma M, Kalluri R, LeBleu VS. Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2. Cell Reports. 10: 1066-81. PMID 25704811 DOI: 10.1016/j.celrep.2015.01.035  1
2015 Tang W, Huan X, Zhang Y, Mahapatra T, Li J, Liu X, Mahapatra S, Yan H, Fu G, Zhao J, Gu C, Detels R. Factors associated with loss-to-follow-up during behavioral interventions and HIV testing cohort among men who have sex with men in Nanjing, China. Plos One. 10: e115691. PMID 25559678 DOI: 10.1371/Journal.Pone.0115691  1
2015 Almasi S, Xu X, Ben-Zvi A, Lacoste B, Gu C, Miller EL. A novel method for identifying a graph-based representation of 3-D microvascular networks from fluorescence microscopy image stacks. Medical Image Analysis. 20: 208-23. PMID 25515433 DOI: 10.1016/J.Media.2014.11.007  1
2014 Gelfand MV, Hagan N, Tata A, Oh WJ, Lacoste B, Kang KT, Kopycinska J, Bischoff J, Wang JH, Gu C. Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding. Elife. 3: e03720. PMID 25244320 DOI: 10.7554/Elife.03720  1
2014 Lacoste B, Comin CH, Ben-Zvi A, Kaeser PS, Xu X, Costa Lda F, Gu C. Sensory-related neural activity regulates the structure of vascular networks in the cerebral cortex. Neuron. 83: 1117-30. PMID 25155955 DOI: 10.1016/J.Neuron.2014.07.034  1
2014 Straub C, Tritsch NX, Hagan NA, Gu C, Sabatini BL. Multiphasic modulation of cholinergic interneurons by nigrostriatal afferents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8557-69. PMID 24948810 DOI: 10.1523/Jneurosci.0589-14.2014  1
2014 Tritsch NX, Oh WJ, Gu C, Sabatini BL. Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis. Elife. 3: e01936. PMID 24843012 DOI: 10.7554/Elife.01936  1
2014 Tata A, Stoppel DC, Hong S, Ben-Zvi A, Xie T, Gu C. An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling. The Journal of Cell Biology. 205: 573-90. PMID 24841563 DOI: 10.1083/jcb.201309004  1
2014 Ben-Zvi A, Lacoste B, Kur E, Andreone BJ, Mayshar Y, Yan H, Gu C. Mfsd2a is critical for the formation and function of the blood-brain barrier. Nature. 509: 507-11. PMID 24828040 DOI: 10.1038/Nature13324  1
2014 Gelfand MV, Hagan N, Tata A, Oh W, Lacoste B, Kang K, Kopycinska J, Bischoff J, Wang J, Gu C. Author response: Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding Elife. DOI: 10.7554/Elife.03720.019  1
2014 Tritsch NX, Oh W, Gu C, Sabatini BL. Author response: Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis Elife. DOI: 10.7554/Elife.01936.017  1
2013 Oh WJ, Gu C. Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism. Neuron. 80: 458-69. PMID 24139045 DOI: 10.1016/j.neuron.2013.09.005  1
2013 Gu C, Giraudo E. The role of semaphorins and their receptors in vascular development and cancer. Experimental Cell Research. 319: 1306-16. PMID 23422037 DOI: 10.1016/j.yexcr.2013.02.003  1
2013 Oh WJ, Gu C. The role and mechanism-of-action of Sema3E and Plexin-D1 in vascular and neural development. Seminars in Cell & Developmental Biology. 24: 156-62. PMID 23270617 DOI: 10.1016/j.semcdb.2012.12.001  1
2012 Kwon HB, Kozorovitskiy Y, Oh WJ, Peixoto RT, Akhtar N, Saulnier JL, Gu C, Sabatini BL. Neuroligin-1-dependent competition regulates cortical synaptogenesis and synapse number. Nature Neuroscience. 15: 1667-74. PMID 23143522 DOI: 10.1038/Nn.3256  1
2012 Ding JB, Oh WJ, Sabatini BL, Gu C. Semaphorin 3E-Plexin-D1 signaling controls pathway-specific synapse formation in the striatum. Nature Neuroscience. 15: 215-23. PMID 22179111 DOI: 10.1038/nn.3003  1
2011 Kim J, Oh WJ, Gaiano N, Yoshida Y, Gu C. Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism. Genes & Development. 25: 1399-411. PMID 21724832 DOI: 10.1101/Gad.2042011  1
2009 Piper M, Plachez C, Zalucki O, Fothergill T, Goudreau G, Erzurumlu R, Gu C, Richards LJ. Neuropilin 1-Sema signaling regulates crossing of cingulate pioneering axons during development of the corpus callosum. Cerebral Cortex (New York, N.Y. : 1991). 19: i11-21. PMID 19357391 DOI: 10.1093/Cercor/Bhp027  1
2009 Gelfand MV, Hong S, Gu C. Guidance from above: common cues direct distinct signaling outcomes in vascular and neural patterning. Trends in Cell Biology. 19: 99-110. PMID 19200729 DOI: 10.1016/j.tcb.2009.01.001  1
2006 Gammill LS, Gonzalez C, Gu C, Bronner-Fraser M. Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signaling. Development (Cambridge, England). 133: 99-106. PMID 16319111 DOI: 10.1242/Dev.02187  1
2005 Huber AB, Kania A, Tran TS, Gu C, De Marco Garcia N, Lieberam I, Johnson D, Jessell TM, Ginty DD, Kolodkin AL. Distinct roles for secreted semaphorin signaling in spinal motor axon guidance. Neuron. 48: 949-64. PMID 16364899 DOI: 10.1016/J.NEURON.2005.12.003  1
2005 Mukouyama YS, Gerber HP, Ferrara N, Gu C, Anderson DJ. Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback. Development (Cambridge, England). 132: 941-52. PMID 15673567 DOI: 10.1242/dev.01675  1
2005 Gu C, Yoshida Y, Livet J, Reimert DV, Mann F, Merte J, Henderson CE, Jessell TM, Kolodkin AL, Ginty DD. Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science (New York, N.Y.). 307: 265-8. PMID 15550623 DOI: 10.1126/Science.1105416  1
2004 Schwarz Q, Gu C, Fujisawa H, Sabelko K, Gertsenstein M, Nagy A, Taniguchi M, Kolodkin AL, Ginty DD, Shima DT, Ruhrberg C. Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve. Genes & Development. 18: 2822-34. PMID 15545635 DOI: 10.1101/Gad.322904  1
2003 Gu C, Rodriguez ER, Reimert DV, Shu T, Fritzsch B, Richards LJ, Kolodkin AL, Ginty DD. Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development. Developmental Cell. 5: 45-57. PMID 12852851 DOI: 10.1016/S1534-5807(03)00169-2  1
2002 Gu C, Limberg BJ, Whitaker GB, Perman B, Leahy DJ, Rosenbaum JS, Ginty DD, Kolodkin AL. Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165. The Journal of Biological Chemistry. 277: 18069-76. PMID 11886873 DOI: 10.1074/Jbc.M201681200  1
2000 Gu C, Ma YC, Benjamin J, Littman D, Chao MV, Huang XY. Apoptotic signaling through the beta -adrenergic receptor. A new Gs effector pathway. The Journal of Biological Chemistry. 275: 20726-33. PMID 10767282 DOI: 10.1074/Jbc.M000152200  1
1999 Casaccia-Bonnefil P, Gu C, Chao MV. Neurotrophins in cell survival/death decisions. Advances in Experimental Medicine and Biology. 468: 275-82. PMID 10635036 DOI: 10.1007/978-1-4615-4685-6_22  1
1999 Casaccia-Bonnefil P, Gu C, Khursigara G, Chao MV. p75 neurotrophin receptor as a modulator of survival and death decisions. Microscopy Research and Technique. 45: 217-24. PMID 10383114 DOI: 10.1002/(Sici)1097-0029(19990515/01)45:4/5<217::Aid-Jemt5>3.0.Co;2-5  1
1999 Gu C, Casaccia-Bonnefil P, Srinivasan A, Chao MV. Oligodendrocyte apoptosis mediated by caspase activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 3043-9. PMID 10191321 DOI: 10.1523/Jneurosci.19-08-03043.1999  1
1998 Gu C, Castellino A, Chan JY, Chao MV. BRE: a modulator of TNF-alpha action. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1101-8. PMID 9737713 DOI: 10.1096/Fasebj.12.12.1101  1
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