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Jiqiang Ling, Ph.D. - Publications

Affiliations: 
University of Texas Health Science Center at Houston, Houston, TX, United States 
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44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Zhang H, Wu J, Lyu Z, Ling J. Impact of alanyl-tRNA synthetase editing deficiency in yeast. Nucleic Acids Research. PMID 34500470 DOI: 10.1093/nar/gkab766  0.32
2020 Zhang H, Lyu Z, Fan Y, Evans CR, Barber KW, Banerjee K, Igoshin OA, Rinehart J, Ling J. Metabolic stress promotes stop-codon readthrough and phenotypic heterogeneity. Proceedings of the National Academy of Sciences of the United States of America. PMID 32839318 DOI: 10.1073/Pnas.2013543117  0.599
2019 Evans CR, Fan Y, Ling J. Increased Mistranslation Protects E. coli from Protein Misfolding Stress due to Activation of a RpoS-dependent Heat Shock Response. Febs Letters. PMID 31419308 DOI: 10.1002/1873-3468.13578  0.343
2019 Fan Y, Thompson L, Lyu Z, Cameron TA, De Lay NR, Krachler AM, Ling J. Optimal translational fidelity is critical for Salmonella virulence and host interactions. Nucleic Acids Research. PMID 30941426 DOI: 10.1093/Nar/Gkz229  0.344
2018 O'Donoghue P, Ling J, Söll D. Transfer RNA function and evolution. Rna Biology. 15: 423-426. PMID 30099966 DOI: 10.1080/15476286.2018.1478942  0.442
2017 Evans CR, Ling J. Visualizing translational errors: one cell at a time. Current Genetics. PMID 29159424 DOI: 10.1007/S00294-017-0784-6  0.305
2017 Fan Y, Evans CR, Barber KW, Banerjee K, Weiss KJ, Margolin W, Igoshin OA, Rinehart J, Ling J. Heterogeneity of Stop Codon Readthrough in Single Bacterial Cells and Implications for Population Fitness. Molecular Cell. PMID 28781237 DOI: 10.1016/J.Molcel.2017.07.010  0.536
2017 Leshinsky-Silver E, Ling J, Wu J, Vinkler C, Yosovich K, Bahar S, Yanoov-Sharav M, Lerman-Sagie T, Lev D. Severe growth deficiency, microcephaly, intellectual disability, and characteristic facial features are due to a homozygous QARS mutation. Neurogenetics. PMID 28620870 DOI: 10.1007/S10048-017-0516-6  0.311
2017 Nakayama T, Wu J, Galvin-Parton P, Weiss J, Andriola MR, Hill RS, Vaughan D, El-Quessny M, Barry BJ, Partlow JN, Barkovich AJ, Ling J, Mochida GH. Deficient activity of alanyl-tRNA synthetase underlies an autosomal recessive syndrome of progressive microcephaly, hypomyelination, and epileptic encephalopathy. Human Mutation. PMID 28493438 DOI: 10.1002/Humu.23250  0.41
2017 Mohler K, Aerni HR, Gassaway B, Ling J, Ibba M, Rinehart J. MS-READ: Quantitative Measurement of Amino Acid Incorporation. Biochimica Et Biophysica Acta. PMID 28130155 DOI: 10.1016/J.Bbagen.2017.01.025  0.601
2017 Fan Y, Evans CR, Ling J. Rewiring Protein Synthesis: From Natural to Synthetic Amino Acids. Biochimica Et Biophysica Acta. PMID 28095316 DOI: 10.1016/J.Bbagen.2017.01.014  0.418
2016 Fan Y, Evans CR, Ling J. Reduced Protein Synthesis Fidelity Inhibits Flagellar Biosynthesis and Motility. Scientific Reports. 6: 30960. PMID 27468805 DOI: 10.1038/Srep30960  0.366
2016 Ognjenović J, Wu J, Matthies D, Baxa U, Subramaniam S, Ling J, Simonović M. The crystal structure of human GlnRS provides basis for the development of neurological disorders. Nucleic Acids Research. PMID 26869582 DOI: 10.1093/Nar/Gkw082  0.34
2016 Ho JM, Reynolds NM, Rivera K, Connolly M, Guo LT, Ling J, Pappin DJ, Church GM, Söll D. Efficient Reassignment of a Frequent Serine Codon in Wild-Type Escherichia coli. Acs Synthetic Biology. 5: 163-71. PMID 26544153 DOI: 10.1021/Acssynbio.5B00197  0.555
2015 Holman KM, Wu J, Ling J, Simonović M. The crystal structure of yeast mitochondrial ThrRS in complex with the canonical threonine tRNA. Nucleic Acids Research. PMID 26704982 DOI: 10.1093/Nar/Gkv1501  0.355
2015 Ling J, O'Donoghue P, Söll D. Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology. Nature Reviews. Microbiology. 13: 707-21. PMID 26411296 DOI: 10.1038/Nrmicro3568  0.509
2015 Fan Y, Wu J, Ung MH, De Lay N, Cheng C, Ling J. Protein mistranslation protects bacteria against oxidative stress. Nucleic Acids Research. 43: 1740-8. PMID 25578967 DOI: 10.1093/Nar/Gku1404  0.352
2014 Wu J, Fan Y, Ling J. Mechanism of oxidant-induced mistranslation by threonyl-tRNA synthetase. Nucleic Acids Research. 42: 6523-31. PMID 24744241 DOI: 10.1093/Nar/Gku271  0.327
2014 Zhang X, Ling J, Barcia G, Jing L, Wu J, Barry BJ, Mochida GH, Hill RS, Weimer JM, Stein Q, Poduri A, Partlow JN, Ville D, Dulac O, Yu TW, et al. Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures. American Journal of Human Genetics. 94: 547-58. PMID 24656866 DOI: 10.1016/J.Ajhg.2014.03.003  0.513
2014 Krishnakumar R, Ling J. Experimental challenges of sense codon reassignment: an innovative approach to genetic code expansion. Febs Letters. 588: 383-8. PMID 24333334 DOI: 10.1016/J.Febslet.2013.11.039  0.423
2014 Ling J, Daoud R, Lajoie MJ, Church GM, Söll D, Lang BF. Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria. Nucleic Acids Research. 42: 499-508. PMID 24049072 DOI: 10.1093/Nar/Gkt842  0.584
2013 O'Donoghue P, Ling J, Wang YS, Söll D. Upgrading protein synthesis for synthetic biology. Nature Chemical Biology. 9: 594-8. PMID 24045798 DOI: 10.1038/Nchembio.1339  0.703
2013 Englert M, Moses S, Hohn M, Ling J, O'Donoghue P, Söll D. Aminoacylation of tRNA 2'- or 3'-hydroxyl by phosphoseryl- and pyrrolysyl-tRNA synthetases. Febs Letters. 587: 3360-4. PMID 24021645 DOI: 10.1016/J.Febslet.2013.08.037  0.513
2013 Krishnakumar R, Prat L, Aerni HR, Ling J, Merryman C, Glass JI, Rinehart J, Söll D. Transfer RNA misidentification scrambles sense codon recoding. Chembiochem : a European Journal of Chemical Biology. 14: 1967-72. PMID 24000185 DOI: 10.1002/Cbic.201300444  0.682
2012 Ling J, Cho C, Guo LT, Aerni HR, Rinehart J, Söll D. Protein aggregation caused by aminoglycoside action is prevented by a hydrogen peroxide scavenger. Molecular Cell. 48: 713-22. PMID 23122414 DOI: 10.1016/J.Molcel.2012.10.001  0.627
2012 O'Donoghue P, Prat L, Heinemann IU, Ling J, Odoi K, Liu WR, Söll D. Near-cognate suppression of amber, opal and quadruplet codons competes with aminoacyl-tRNAPyl for genetic code expansion. Febs Letters. 586: 3931-7. PMID 23036644 DOI: 10.1016/J.Febslet.2012.09.033  0.593
2012 Ling J, Peterson KM, Simonovic I, Söll D, Simonovic M. The mechanism of pre-transfer editing in yeast mitochondrial threonyl-tRNA synthetase. The Journal of Biological Chemistry. 287: 28518-25. PMID 22773845 DOI: 10.1074/Jbc.M112.372920  0.544
2012 Guo LT, Helgadóttir S, Söll D, Ling J. Rational design and directed evolution of a bacterial-type glutaminyl-tRNA synthetase precursor. Nucleic Acids Research. 40: 7967-74. PMID 22661575 DOI: 10.1093/Nar/Gks507  0.563
2012 Ling J, Peterson KM, Simonović I, Cho C, Söll D, Simonović M. Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment. Proceedings of the National Academy of Sciences of the United States of America. 109: 3281-6. PMID 22343532 DOI: 10.1073/Pnas.1200109109  0.581
2012 Helgadóttir S, Sinapah S, Söll D, Ling J. Mutational analysis of Sep-tRNA:Cys-tRNA synthase reveals critical residues for tRNA-dependent cysteine formation. Febs Letters. 586: 60-3. PMID 22166682 DOI: 10.1016/J.Febslet.2011.11.024  0.54
2012 Ling J, Söll D. The genetic code: Yesterday, today, and tomorrow Resonance. 17: 1136-1142. DOI: 10.1007/S12045-012-0130-8  0.483
2011 Su D, Lieberman A, Lang BF, Simonovic M, Söll D, Ling J. An unusual tRNAThr derived from tRNAHis reassigns in yeast mitochondria the CUN codons to threonine. Nucleic Acids Research. 39: 4866-74. PMID 21321019 DOI: 10.1093/Nar/Gkr073  0.567
2010 Reynolds NM, Ling J, Roy H, Banerjee R, Repasky SE, Hamel P, Ibba M. Cell-specific differences in the requirements for translation quality control. Proceedings of the National Academy of Sciences of the United States of America. 107: 4063-8. PMID 20160120 DOI: 10.1073/Pnas.0909640107  0.449
2010 Ling J, Söll D. Severe oxidative stress induces protein mistranslation through impairment of an aminoacyl-tRNA synthetase editing site. Proceedings of the National Academy of Sciences of the United States of America. 107: 4028-33. PMID 20160114 DOI: 10.1073/Pnas.1000315107  0.579
2009 Ling J, Reynolds N, Ibba M. Aminoacyl-tRNA synthesis and translational quality control. Annual Review of Microbiology. 63: 61-78. PMID 19379069 DOI: 10.1146/Annurev.Micro.091208.073210  0.484
2009 Ling J, So BR, Yadavalli SS, Roy H, Shoji S, Fredrick K, Musier-Forsyth K, Ibba M. Resampling and editing of mischarged tRNA prior to translation elongation. Molecular Cell. 33: 654-60. PMID 19285947 DOI: 10.1016/J.Molcel.2009.01.031  0.491
2007 Ling J, Roy H, Qin D, Rubio MA, Alfonzo JD, Fredrick K, Ibba M. Pathogenic mechanism of a human mitochondrial tRNAPhe mutation associated with myoclonic epilepsy with ragged red fibers syndrome. Proceedings of the National Academy of Sciences of the United States of America. 104: 15299-304. PMID 17878308 DOI: 10.1073/Pnas.0704441104  0.37
2007 Ling J, Yadavalli SS, Ibba M. Phenylalanyl-tRNA synthetase editing defects result in efficient mistranslation of phenylalanine codons as tyrosine. Rna (New York, N.Y.). 13: 1881-6. PMID 17804641 DOI: 10.1261/Rna.684107  0.436
2007 Hausmann CD, Ling J, Ibba M. The unnatural culture of amino acids. Nature Methods. 4: 205-6. PMID 17327846 DOI: 10.1038/Nmeth0307-205  0.375
2007 Ling J, Roy H, Ibba M. Mechanism of tRNA-dependent editing in translational quality control. Proceedings of the National Academy of Sciences of the United States of America. 104: 72-7. PMID 17185419 DOI: 10.1073/Pnas.0606272104  0.489
2005 Roy H, Ling J, Alfonzo J, Ibba M. Loss of editing activity during the evolution of mitochondrial phenylalanyl-tRNA synthetase. The Journal of Biological Chemistry. 280: 38186-92. PMID 16162501 DOI: 10.1074/Jbc.M508281200  0.442
2004 Roy H, Ling J, Irnov M, Ibba M. Post-transfer editing in vitro and in vivo by the beta subunit of phenylalanyl-tRNA synthetase. The Embo Journal. 23: 4639-48. PMID 15526031 DOI: 10.1038/Sj.Emboj.7600474  0.456
2003 Di Y, Li J, Zhang Y, He X, Lu H, Xu D, Ling J, Huo K, Wan D, Li YY, Gu J. HCC-associated protein HCAP1, a variant of GEMIN4, interacts with zinc-finger proteins. Journal of Biochemistry. 133: 713-8. PMID 12869526 DOI: 10.1093/Jb/Mvg091  0.36
2003 Di Y, Li J, Fang J, Xu Z, He X, Zhang F, Ling J, Li X, Xu D, Li L, Li YY, Huo K. Cloning and characterization of a novel gene which encodes a protein interacting with the mitosis-associated kinase-like protein NTKL. Journal of Human Genetics. 48: 315-21. PMID 12783284 DOI: 10.1007/S10038-003-0031-5  0.362
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