Maiken Nedergaard - Publications

Affiliations: 
University of Rochester Medical Center, Rochester, NY, United States 

87/419 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hussain R, Tithof J, Wang W, Cheetham-West A, Song W, Peng W, Sigurdsson B, Kim D, Sun Q, Peng S, Plá V, Kelley DH, Hirase H, Castorena-Gonzalez JA, Weikop P, ... ... Nedergaard M, et al. Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema. Nature. PMID 37968397 DOI: 10.1038/s41586-023-06737-7  0.458
2023 Dietz AG, Weikop P, Hauglund N, Andersen M, Petersen NC, Rose L, Hirase H, Nedergaard M. Local extracellular K in cortex regulates norepinephrine levels, network state, and behavioral output. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305071120. PMID 37774097 DOI: 10.1073/pnas.2305071120  0.586
2023 Holstein-Rønsbo S, Gan Y, Giannetto MJ, Rasmussen MK, Sigurdsson B, Beinlich FRM, Rose L, Untiet V, Hablitz LM, Kelley DH, Nedergaard M. Publisher Correction: Glymphatic influx and clearance are accelerated by neurovascular coupling. Nature Neuroscience. PMID 37667041 DOI: 10.1038/s41593-023-01441-1  0.732
2023 Holstein-Rønsbo S, Gan Y, Giannetto MJ, Rasmussen MK, Sigurdsson B, Beinlich FRM, Rose L, Untiet V, Hablitz LM, Kelley DH, Nedergaard M. Glymphatic influx and clearance are accelerated by neurovascular coupling. Nature Neuroscience. 26: 1042-1053. PMID 37264158 DOI: 10.1038/s41593-023-01327-2  0.763
2023 Untiet V, Beinlich FRM, Kusk P, Kang N, Ladrón-de-Guevara A, Song W, Kjaerby C, Andersen M, Hauglund N, Bojarowska Z, Sigurdsson B, Deng S, Hirase H, Petersen NC, Verkhratsky A, ... Nedergaard M, et al. Astrocytic chloride is brain state dependent and modulates inhibitory neurotransmission in mice. Nature Communications. 14: 1871. PMID 37015909 DOI: 10.1038/s41467-023-37433-9  0.657
2023 Gomolka RS, Hablitz LM, Mestre H, Giannetto M, Du T, Hauglund NL, Xie L, Peng W, Martinez PM, Nedergaard M, Mori Y. Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation. Elife. 12. PMID 36757363 DOI: 10.7554/eLife.82232  0.781
2022 Wang X, Delle C, Asiminas A, Akther S, Vittani M, Brøgger P, Kusk P, Vo CT, Radovanovic T, Konno A, Hirai H, Fukuda M, Weikop P, Goldman SA, Nedergaard M, et al. Liver-secreted fluorescent blood plasma markers enable chronic imaging of the microcirculation. Cell Reports Methods. 2: 100302. PMID 36313804 DOI: 10.1016/j.crmeth.2022.100302  0.407
2022 Carlsen EMM, Nedergaard M, Rasmussen RN. Versatile treadmill system for measuring locomotion and neural activity in head-fixed mice. Star Protocols. 3: 101701. PMID 36107745 DOI: 10.1016/j.xpro.2022.101701  0.424
2022 Plá V, Bork P, Harnpramukkul A, Olveda G, Ladrón-de-Guevara A, Giannetto MJ, Hussain R, Wang W, Kelley DH, Hablitz LM, Nedergaard M. A real-time in vivo clearance assay for quantification of glymphatic efflux. Cell Reports. 40: 111320. PMID 36103828 DOI: 10.1016/j.celrep.2022.111320  0.771
2021 Hablitz LM, Nedergaard M. The glymphatic system. Current Biology : Cb. 31: R1371-R1375. PMID 34699796 DOI: 10.1016/j.cub.2021.08.026  0.742
2021 Hablitz LM, Nedergaard M. The Glymphatic System: A Novel Component of Fundamental Neurobiology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 41: 7698-7711. PMID 34526407 DOI: 10.1523/JNEUROSCI.0619-21.2021  0.776
2021 Rasmussen MK, Mestre H, Nedergaard M. Fluid Transport in the Brain. Physiological Reviews. PMID 33949874 DOI: 10.1152/physrev.00031.2020  0.318
2020 Goldman N, Hablitz LM, Mori Y, Nedergaard M. The Glymphatic System and Pain. Medical Acupuncture. 32: 373-376. PMID 33362890 DOI: 10.1089/acu.2020.1489  0.742
2020 Nedergaard M, Goldman SA. Glymphatic failure as a final common pathway to dementia. Science (New York, N.Y.). 370: 50-56. PMID 33004510 DOI: 10.1126/science.abb8739  0.408
2020 Giannetto M, Xia M, Stæger FF, Metcalfe T, Vinitsky HS, Dang JAML, Xavier ALR, Kress BT, Nedergaard M, Hablitz LM. Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice. Scientific Reports. 10: 16073. PMID 32999319 DOI: 10.1038/s41598-020-72621-3  0.766
2020 Hablitz LM, Plá V, Giannetto M, Vinitsky HS, Stæger FF, Metcalfe T, Nguyen R, Benrais A, Nedergaard M. Circadian control of brain glymphatic and lymphatic fluid flow. Nature Communications. 11: 4411. PMID 32879313 DOI: 10.1038/s41467-020-18115-2  0.773
2020 Windrem MS, Schanz SJ, Zou L, Chandler-Militello D, Kuypers NJ, Nedergaard M, Lu Y, Mariani JN, Goldman SA. Human Glial Progenitor Cells Effectively Remyelinate the Demyelinated Adult Brain. Cell Reports. 31: 107658. PMID 32433967 DOI: 10.1016/J.Celrep.2020.107658  0.441
2020 Rasmussen R, O'Donnell J, Ding F, Nedergaard M. Interstitial ions: A key regulator of state-dependent neural activity? Progress in Neurobiology. 101802. PMID 32413398 DOI: 10.1016/J.Pneurobio.2020.101802  0.424
2020 Wang X, Lou N, Eberhardt A, Yang Y, Kusk P, Xu Q, Förstera B, Peng S, Shi M, Ladrón-de-Guevara A, Delle C, Sigurdsson B, Xavier ALR, Ertürk A, Libby RT, ... ... Nedergaard M, et al. An ocular glymphatic clearance system removes β-amyloid from the rodent eye. Science Translational Medicine. 12. PMID 32213628 DOI: 10.1126/Scitranslmed.Aaw3210  0.355
2019 Dietz AG, Goldman SA, Nedergaard M. Glial cells in schizophrenia: a unified hypothesis. The Lancet. Psychiatry. PMID 31704113 DOI: 10.1016/S2215-0366(19)30302-5  0.416
2019 Sweeney AM, Plá V, Du T, Liu G, Sun Q, Peng S, Plog BA, Kress BT, Wang X, Mestre H, Nedergaard M. In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy. Journal of Visualized Experiments : Jove. PMID 31403617 DOI: 10.3791/59774  0.377
2019 Rasmussen R, Nicholas E, Petersen NC, Dietz AG, Xu Q, Sun Q, Nedergaard M. Cortex-wide Changes in Extracellular Potassium Ions Parallel Brain State Transitions in Awake Behaving Mice. Cell Reports. 28: 1182-1194.e4. PMID 31365863 DOI: 10.1016/J.Celrep.2019.06.082  0.663
2019 Wang M, Qin C, Luo X, Wang J, Wang X, Xie M, Hu J, Cao J, Hu T, Goldman SA, Nedergaard M, Wang W. Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease. Theranostics. 9: 4474-4493. PMID 31285774 DOI: 10.7150/thno.31942  0.431
2019 Smith NA, Bekar LK, Nedergaard M. Astrocytic Endocannabinoids Mediate Hippocampal Transient Heterosynaptic Depression. Neurochemical Research. PMID 31254249 DOI: 10.1007/S11064-019-02834-0  0.481
2019 Liu Z, Osipovitch M, Benraiss A, Huynh NPT, Foti R, Bates J, Chandler-Militello D, Findling RL, Tesar PJ, Nedergaard M, Windrem MS, Goldman SA. Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling. Cell Reports. 27: 3832-3843.e6. PMID 31242417 DOI: 10.1016/j.celrep.2019.05.088  0.421
2019 Hablitz LM, Vinitsky HS, Sun Q, Stæger FF, Sigurdsson B, Mortensen KN, Lilius TO, Nedergaard M. Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia. Science Advances. 5: eaav5447. PMID 30820460 DOI: 10.1126/sciadv.aav5447  0.768
2018 Mestre H, Hablitz LM, Xavier AL, Feng W, Zou W, Pu T, Monai H, Murlidharan G, Castellanos Rivera RM, Simon MJ, Pike MM, Plá V, Du T, Kress BT, Wang X, ... ... Nedergaard M, et al. Aquaporin-4-dependent glymphatic solute transport in the rodent brain. Elife. 7. PMID 30561329 DOI: 10.7554/Elife.40070  0.779
2018 Obara-Michlewska M, Ding F, Popek M, Verkhratsky A, Nedergaard M, Zielinska M, Albrecht J. Interstitial ion homeostasis and acid-base balance are maintained in oedematous brain of mice with acute toxic liver failure. Neurochemistry International. PMID 29772253 DOI: 10.1016/j.neuint.2018.05.007  0.304
2018 Smith NA, Kress BT, Lu Y, Chandler-Militello D, Benraiss A, Nedergaard M. Fluorescent Ca2+ indicators directly inhibit the Na,K-ATPase and disrupt cellular functions. Science Signaling. 11. PMID 29382785 DOI: 10.1126/Scisignal.Aal2039  0.454
2017 Holstein-Rathlou SV, Petersen NC, Nedergaard M. Voluntary running enhances glymphatic influx in awake behaving, young mice. Neuroscience Letters. PMID 29079431 DOI: 10.1016/J.Neulet.2017.10.035  0.629
2017 Windrem MS, Osipovitch M, Liu Z, Bates J, Chandler-Militello D, Zou L, Munir J, Schanz S, McCoy K, Miller RH, Wang S, Nedergaard M, Findling RL, Tesar PJ, Goldman SA. Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia. Cell Stem Cell. PMID 28736215 DOI: 10.1016/J.Stem.2017.06.012  0.465
2017 Sun W, Cornwell A, Li J, Peng S, Osorio MJ, Su Wanga NA, Benraiss A, Lou N, Goldman SA, Nedergaard M. SOX9 is an astrocyte-specific nuclear marker in the adult brain outside the neurogenic regions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28336567 DOI: 10.1523/JNEUROSCI.3199-16.2017  0.485
2017 Kjaerby C, Rasmussen R, Andersen M, Nedergaard M. Does Global Astrocytic Calcium Signaling Participate in Awake Brain State Transitions and Neuronal Circuit Function? Neurochemical Research. PMID 28210958 DOI: 10.1007/s11064-017-2195-y  0.464
2016 Wang F, Wang X, Shapiro LA, Cotrina ML, Liu W, Wang EW, Gu S, Wang W, He X, Nedergaard M, Huang JH. NKCC1 up-regulation contributes to early post-traumatic seizures and increased post-traumatic seizure susceptibility. Brain Structure & Function. PMID 27586142 DOI: 10.1007/S00429-016-1292-Z  0.317
2016 Rasmussen R, Nedergaard M, Petersen NC. Sulforhodamine 101, a widely used astrocyte marker, can induce cortical seizure-like activity at concentrations commonly used. Scientific Reports. 6: 30433. PMID 27457281 DOI: 10.1038/Srep30433  0.665
2016 Benraiss A, Wang S, Herrlinger S, Li X, Chandler-Militello D, Mauceri J, Burm HB, Toner M, Osipovitch M, Jim Xu Q, Ding F, Wang F, Kang N, Kang J, Curtin PC, ... ... Nedergaard M, et al. Human glia can both induce and rescue aspects of disease phenotype in Huntington disease. Nature Communications. 7: 11758. PMID 27273432 DOI: 10.1038/ncomms11758  0.455
2016 Nedergaard M, Goldman SA. BRAIN DRAIN. Scientific American. 314: 44-9. PMID 27066643  0.459
2016 Lou N, Takano T, Pei Y, Xavier AL, Goldman SA, Nedergaard M. Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier. Proceedings of the National Academy of Sciences of the United States of America. PMID 26755608 DOI: 10.1073/pnas.1520398113  0.471
2015 Iliff JJ, Goldman SA, Nedergaard M. Implications of the discovery of brain lymphatic pathways. The Lancet. Neurology. 14: 977-9. PMID 26376966 DOI: 10.1016/S1474-4422(15)00221-5  0.481
2015 Ribeiro Xavier AL, Kress BT, Goldman SA, Lacerda de Menezes JR, Nedergaard M. A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11848-61. PMID 26311768 DOI: 10.1523/JNEUROSCI.1217-15.2015  0.47
2015 Goldman SA, Nedergaard M, Windrem MS. Modeling cognition and disease using human glial chimeric mice. Glia. 63: 1483-93. PMID 26010831 DOI: 10.1002/glia.22862  0.465
2014 Fujita T, Chen MJ, Li B, Smith NA, Peng W, Sun W, Toner MJ, Kress BT, Wang L, Benraiss A, Takano T, Wang S, Nedergaard M. Neuronal transgene expression in dominant-negative SNARE mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16594-604. PMID 25505312 DOI: 10.1523/Jneurosci.2585-14.2014  0.514
2014 Xavier AL, Menezes JR, Goldman SA, Nedergaard M. Fine-tuning the central nervous system: microglial modelling of cells and synapses. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130593. PMID 25225087 DOI: 10.1098/rstb.2013.0593  0.453
2014 Tong J, Ren Y, Wang X, Dimopoulos VG, Kesler HN, Liu W, He X, Nedergaard M, Huang JH. Assessment of Nogo-66 receptor 1 function in vivo after spinal cord injury. Neurosurgery. 75: 51-60. PMID 24594926 DOI: 10.1227/NEU.0000000000000337  0.316
2013 Rangroo Thrane V, Thrane AS, Wang F, Cotrina ML, Smith NA, Chen M, Xu Q, Kang N, Fujita T, Nagelhus EA, Nedergaard M. Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering. Nature Medicine. 19: 1643-8. PMID 24240184 DOI: 10.1038/Nm.3400  0.539
2013 Wang F, Smith NA, Xu Q, Goldman S, Peng W, Huang JH, Takano T, Nedergaard M. Photolysis of caged Ca2+ but not receptor-mediated Ca2+ signaling triggers astrocytic glutamate release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17404-12. PMID 24174673 DOI: 10.1523/Jneurosci.2178-13.2013  0.47
2013 Benraiss A, Toner MJ, Xu Q, Bruel-Jungerman E, Rogers EH, Wang F, Economides AN, Davidson BL, Kageyama R, Nedergaard M, Goldman SA. Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease. Cell Stem Cell. 12: 787-99. PMID 23746982 DOI: 10.1016/J.Stem.2013.04.014  0.446
2013 Han X, Chen M, Wang F, Windrem M, Wang S, Shanz S, Xu Q, Oberheim NA, Bekar L, Betstadt S, Silva AJ, Takano T, Goldman SA, Nedergaard M. Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice. Cell Stem Cell. 12: 342-53. PMID 23472873 DOI: 10.1016/j.stem.2012.12.015  0.461
2012 Goldman SA, Nedergaard M, Windrem MS. Glial progenitor cell-based treatment and modeling of neurological disease. Science (New York, N.Y.). 338: 491-5. PMID 23112326 DOI: 10.1126/science.1218071  0.426
2012 Iliff JJ, Wang M, Liao Y, Plogg BA, Peng W, Gundersen GA, Benveniste H, Vates GE, Deane R, Goldman SA, Nagelhus EA, Nedergaard M. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β. Science Translational Medicine. 4: 147ra111. PMID 22896675 DOI: 10.1126/Scitranslmed.3003748  0.529
2012 Wang F, Smith NA, Xu Q, Fujita T, Baba A, Matsuda T, Takano T, Bekar L, Nedergaard M. Astrocytes modulate neural network activity by Ca²+-dependent uptake of extracellular K+. Science Signaling. 5: ra26. PMID 22472648 DOI: 10.1126/Scisignal.2002334  0.479
2012 Lovatt D, Xu Q, Liu W, Takano T, Smith NA, Schnermann J, Tieu K, Nedergaard M. Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 6265-70. PMID 22421436 DOI: 10.1073/Pnas.1120997109  0.461
2012 Oberheim NA, Goldman SA, Nedergaard M. Heterogeneity of astrocytic form and function. Methods in Molecular Biology (Clifton, N.J.). 814: 23-45. PMID 22144298 DOI: 10.1007/978-1-61779-452-0_3  0.478
2012 Fujita T, Williams EK, Jensen TK, Smith NA, Takano T, Tieu K, Nedergaard M. Cultured astrocytes do not release adenosine during hypoxic conditions. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: e1-7. PMID 21989480 DOI: 10.1038/Jcbfm.2011.142  0.437
2010 Zhang S, Li B, Lovatt D, Xu J, Song D, Goldman SA, Nedergaard M, Hertz L, Peng L. 5-HT2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional 'serotonin-specific reuptake inhibitors'. Neuron Glia Biology. 6: 113-25. PMID 20846463 DOI: 10.1017/S1740925X10000141  0.429
2010 Hertz L, Lovatt D, Goldman SA, Nedergaard M. Adrenoceptors in brain: cellular gene expression and effects on astrocytic metabolism and [Ca(2+)]i. Neurochemistry International. 57: 411-20. PMID 20380860 DOI: 10.1016/j.neuint.2010.03.019  0.454
2009 Peng W, Cotrina ML, Han X, Yu H, Bekar L, Blum L, Takano T, Tian GF, Goldman SA, Nedergaard M. Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury. Proceedings of the National Academy of Sciences of the United States of America. 106: 12489-93. PMID 19666625 DOI: 10.1073/pnas.0902531106  0.405
2009 Oberheim NA, Takano T, Han X, He W, Lin JH, Wang F, Xu Q, Wyatt JD, Pilcher W, Ojemann JG, Ransom BR, Goldman SA, Nedergaard M. Uniquely hominid features of adult human astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3276-87. PMID 19279265 DOI: 10.1523/Jneurosci.4707-08.2009  0.465
2008 Windrem MS, Schanz SJ, Guo M, Tian GF, Washco V, Stanwood N, Rasband M, Roy NS, Nedergaard M, Havton LA, Wang S, Goldman SA. Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse. Cell Stem Cell. 2: 553-65. PMID 18522848 DOI: 10.1016/J.Stem.2008.03.020  0.446
2007 Lovatt D, Sonnewald U, Waagepetersen HS, Schousboe A, He W, Lin JH, Han X, Takano T, Wang S, Sim FJ, Goldman SA, Nedergaard M. The transcriptome and metabolic gene signature of protoplasmic astrocytes in the adult murine cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12255-66. PMID 17989291 DOI: 10.1523/JNEUROSCI.3404-07.2007  0.495
2007 Ballabh P, Xu H, Hu F, Braun A, Smith K, Rivera A, Lou N, Ungvari Z, Goldman SA, Csiszar A, Nedergaard M. Angiogenic inhibition reduces germinal matrix hemorrhage. Nature Medicine. 13: 477-85. PMID 17401377 DOI: 10.1038/nm1558  0.364
2007 Lin JH, Takano T, Arcuino G, Wang X, Hu F, Darzynkiewicz Z, Nunes M, Goldman SA, Nedergaard M. Purinergic signaling regulates neural progenitor cell expansion and neurogenesis. Developmental Biology. 302: 356-66. PMID 17188262 DOI: 10.1016/J.Ydbio.2006.09.017  0.446
2006 Oberheim NA, Wang X, Goldman S, Nedergaard M. Astrocytic complexity distinguishes the human brain. Trends in Neurosciences. 29: 547-53. PMID 16938356 DOI: 10.1016/j.tins.2006.08.004  0.456
2005 Singh Roy N, Nakano T, Xuing L, Kang J, Nedergaard M, Goldman SA. Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells. Experimental Neurology. 196: 224-34. PMID 16198339 DOI: 10.1016/j.expneurol.2005.06.021  0.424
2004 Wang X, Arcuino G, Takano T, Lin J, Peng WG, Wan P, Li P, Xu Q, Liu QS, Goldman SA, Nedergaard M. P2X7 receptor inhibition improves recovery after spinal cord injury. Nature Medicine. 10: 821-7. PMID 15258577 DOI: 10.1038/nm1082  0.4
2004 Roy NS, Nakano T, Keyoung HM, Windrem M, Rashbaum WK, Alonso ML, Kang J, Peng W, Carpenter MK, Lin J, Nedergaard M, Goldman SA. Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord. Nature Biotechnology. 22: 297-305. PMID 14990951 DOI: 10.1038/nbt944  0.436
2003 Nedergaard M, Ransom B, Goldman SA. New roles for astrocytes: redefining the functional architecture of the brain. Trends in Neurosciences. 26: 523-30. PMID 14522144 DOI: 10.1016/j.tins.2003.08.008  0.507
2003 Nunes MC, Roy NS, Keyoung HM, Goodman RR, McKhann G, Jiang L, Kang J, Nedergaard M, Goldman SA. Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain. Nature Medicine. 9: 439-47. PMID 12627226 DOI: 10.1038/nm837  0.461
2002 Goldman SA, Nedergaard M. Erythropoietin strikes a new cord. Nature Medicine. 8: 785-7. PMID 12152030 DOI: 10.1038/nm0802-785  0.361
2002 Lin JH, Takano T, Cotrina ML, Arcuino G, Kang J, Liu S, Gao Q, Jiang L, Li F, Lichtenberg-Frate H, Haubrich S, Willecke K, Goldman SA, Nedergaard M. Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4302-11. PMID 12040035 DOI: 10.1523/Jneurosci.22-11-04302.2002  0.448
2000 Roy NS, Wang S, Jiang L, Kang J, Benraiss A, Harrison-Restelli C, Fraser RA, Couldwell WT, Kawaguchi A, Okano H, Nedergaard M, Goldman SA. In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus. Nature Medicine. 6: 271-7. PMID 10700228 DOI: 10.1038/73119  0.421
2000 Roy NS, Benraiss A, Wang S, Fraser RA, Goodman R, Couldwell WT, Nedergaard M, Kawaguchi A, Okano H, Goldman SA. Promoter-targeted selection and isolation of neural progenitor cells from the adult human ventricular zone. Journal of Neuroscience Research. 59: 321-31. PMID 10679767 DOI: 10.1002/(Sici)1097-4547(20000201)59:3<321::Aid-Jnr5>3.0.Co;2-9  0.439
2000 Grafstein B, Liu S, Cotrina ML, Goldman SA, Nedergaard M. Meningeal cells can communicate with astrocytes by calcium signaling. Annals of Neurology. 47: 18-25. PMID 10632097 DOI: 10.1002/1531-8249(200001)47:1<18::Aid-Ana6>3.0.Co;2-N  0.403
1999 Simard M, Couldwell WT, Zhang W, Song H, Liu S, Cotrina ML, Goldman S, Nedergaard M. Glucocorticoids-potent modulators of astrocytic calcium signaling. Glia. 28: 1-12. PMID 10498817 DOI: 10.1002/(SICI)1098-1136(199910)28:1<1::AID-GLIA1>3.0.CO;2-4  0.455
1999 Williams S, Leventhal C, Lemmon V, Nedergaard M, Goldman SA. Estrogen promotes the initial migration and inception of NgCAM-dependent calcium-signaling by new neurons of the adult songbird brain. Molecular and Cellular Neurosciences. 13: 41-55. PMID 10049530 DOI: 10.1006/mcne.1998.0729  0.417
1998 Kang J, Jiang L, Goldman SA, Nedergaard M. Astrocyte-mediated potentiation of inhibitory synaptic transmission. Nature Neuroscience. 1: 683-92. PMID 10196584 DOI: 10.1038/3684  0.41
1998 Lin JH, Weigel H, Cotrina ML, Liu S, Bueno E, Hansen AJ, Hansen TW, Goldman S, Nedergaard M. Gap-junction-mediated propagation and amplification of cell injury. Nature Neuroscience. 1: 494-500. PMID 10196547 DOI: 10.1038/2210  0.414
1998 Pincus DW, Keyoung HM, Harrison-Restelli C, Goodman RR, Fraser RA, Edgar M, Sakakibara S, Okano H, Nedergaard M, Goldman SA. Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells. Annals of Neurology. 43: 576-85. PMID 9585351 DOI: 10.1002/Ana.410430505  0.449
1998 Pincus DW, Goodman RR, Fraser RA, Nedergaard M, Goldman SA. Neural stem and progenitor cells: a strategy for gene therapy and brain repair. Neurosurgery. 42: 858-67; discussion 8. PMID 9574651 DOI: 10.1097/00006123-199804000-00103  0.477
1997 Pincus DW, Harrison-Restelli C, Barry J, Goodman RR, Fraser RA, Nedergaard M, Goldman SA. In vitro neurogenesis by adult human epileptic temporal neocortex. Clinical Neurosurgery. 44: 17-25. PMID 10079997  0.377
1997 Goldman SA, Nedergaard M, Crystal RG, Fraser RA, Goodman R, Harrison-Restelli C, Jiang J, Keyoung HM, Leventhal C, Pincus DW, Shahar A, Wang S. Neural precursors and neuronal production in the adult mammalian forebrain. Annals of the New York Academy of Sciences. 835: 30-55. PMID 9616760 DOI: 10.1111/J.1749-6632.1997.Tb48616.X  0.405
1996 Goldman SA, Williams S, Barami K, Lemmon V, Nedergaard M. Transient coupling of Ng-CAM expression to NgCAM-dependent calcium signaling during migration of new neurons in the adult songbird brain. Molecular and Cellular Neurosciences. 7: 29-45. PMID 8812057 DOI: 10.1006/mcne.1996.0003  0.437
1995 Nedergaard M, Cooper AJ, Goldman SA. Gap junctions are required for the propagation of spreading depression. Journal of Neurobiology. 28: 433-44. PMID 8592104 DOI: 10.1002/neu.480280404  0.432
1994 Kirschenbaum B, Nedergaard M, Preuss A, Barami K, Fraser RA, Goldman SA. In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain. Cerebral Cortex (New York, N.Y. : 1991). 4: 576-89. PMID 7703685 DOI: 10.1093/Cercor/4.6.576  0.442
1993 Nedergaard M, Goldman SA. Carrier-mediated transport of lactic acid in cultured neurons and astrocytes. The American Journal of Physiology. 265: R282-9. PMID 8368382 DOI: 10.1152/Ajpregu.1993.265.2.R282  0.436
1992 Goldman SA, Nedergaard M. Newly generated neurons of the adult songbird brain become functionally active in long-term culture. Brain Research. Developmental Brain Research. 68: 217-23. PMID 1394968 DOI: 10.1016/0165-3806(92)90063-3  0.436
1991 Nedergaard M, Goldman SA, Desai S, Pulsinelli WA. Acid-induced death in neurons and glia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2489-97. PMID 1869926 DOI: 10.1523/Jneurosci.11-08-02489.1991  0.391
Low-probability matches (unlikely to be authored by this person)
2020 Rangroo Thrane V, Hynnekleiv L, Wang X, Thrane AS, Krohn J, Nedergaard M. Twists and turns of ocular glymphatic clearance - new study reveals surprising findings in glaucoma. Acta Ophthalmologica. PMID 32706172 DOI: 10.1111/aos.14524  0.294
2023 Miyakoshi LM, Stæger FF, Li Q, Pan C, Xie L, Kang H, Pavan C, Dang J, Sun Q, Ertürk A, Nedergaard M. The state of brain activity modulates cerebrospinal fluid transport. Progress in Neurobiology. 102512. PMID 37482196 DOI: 10.1016/j.pneurobio.2023.102512  0.291
2013 Yang L, Kress BT, Weber HJ, Thiyagarajan M, Wang B, Deane R, Benveniste H, Iliff JJ, Nedergaard M. Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer. Journal of Translational Medicine. 11: 107. PMID 23635358 DOI: 10.1186/1479-5876-11-107  0.286
2021 Mogensen FL, Delle C, Nedergaard M. The Glymphatic System (En)during Inflammation. International Journal of Molecular Sciences. 22. PMID 34299111 DOI: 10.3390/ijms22147491  0.284
2021 Du T, Mestre H, Kress BT, Liu G, Sweeney AM, Samson AJ, Rasmussen MK, Mortensen KN, Bork PAR, Peng W, Olveda GE, Bashford L, Toro ER, Tithof J, Kelley DH, ... ... Nedergaard M, et al. Cerebrospinal fluid is a significant fluid source for anoxic cerebral oedema. Brain : a Journal of Neurology. PMID 34581781 DOI: 10.1093/brain/awab293  0.282
2022 Mestre H, Verma N, Greene TD, Lin LA, Ladron-de-Guevara A, Sweeney AM, Liu G, Thomas VK, Galloway CA, de Mesy Bentley KL, Nedergaard M, Mehta RI. Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer's disease. Nature Communications. 13: 3897. PMID 35794106 DOI: 10.1038/s41467-022-31257-9  0.28
2018 Rasmussen MK, Mestre H, Nedergaard M. The glymphatic pathway in neurological disorders. The Lancet. Neurology. 17: 1016-1024. PMID 30353860 DOI: 10.1016/S1474-4422(18)30318-1  0.279
2019 Plog BA, Lou N, Pierre CA, Cove A, Kenney HM, Hitomi E, Kang H, Iliff JJ, Zeppenfeld DM, Nedergaard M, Vates GE. When the air hits your brain: decreased arterial pulsatility after craniectomy leading to impaired glymphatic flow. Journal of Neurosurgery. 1-14. PMID 31100725 DOI: 10.3171/2019.2.JNS182675  0.279
2017 Plog BA, Nedergaard M. The Glymphatic System in Central Nervous System Health and Disease: Past, Present, and Future. Annual Review of Pathology. PMID 29195051 DOI: 10.1146/annurev-pathol-051217-111018  0.271
2004 Simard M, Nedergaard M. The neurobiology of glia in the context of water and ion homeostasis. Neuroscience. 129: 877-96. PMID 15561405 DOI: 10.1016/j.neuroscience.2004.09.053  0.27
2016 Achariyar TM, Li B, Peng W, Verghese PB, Shi Y, McConnell E, Benraiss A, Kasper T, Song W, Takana T, Holtzman DM, Nedergaard M, Deane R. Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation. Molecular Neurodegeneration. 11: 74. PMID 27931262 DOI: 10.1186/S13024-016-0138-8  0.27
2013 Iliff JJ, Lee H, Yu M, Feng T, Logan J, Nedergaard M, Benveniste H. Brain-wide pathway for waste clearance captured by contrast-enhanced MRI. The Journal of Clinical Investigation. 123: 1299-309. PMID 23434588 DOI: 10.1172/Jci67677  0.269
2012 Rangroo Thrane V, Thrane AS, Chang J, Chanag J, Alleluia V, Nagelhus EA, Nedergaard M. Real-time analysis of microglial activation and motility in hepatic and hyperammonemic encephalopathy. Neuroscience. 220: 247-55. PMID 22728097 DOI: 10.1016/j.neuroscience.2012.06.022  0.267
2017 Ratner V, Gao Y, Lee H, Elkin R, Nedergaard M, Benveniste H, Tannenbaum A. Cerebrospinal and Interstitial Fluid Transport via the Glymphatic Pathway Modeled by Optimal Mass Transport. Neuroimage. PMID 28323163 DOI: 10.1016/j.neuroimage.2017.03.021  0.267
2017 Wang M, Ding F, Deng S, Guo X, Wang W, Iliff JJ, Nedergaard M. Focal solute trapping and global glymphatic pathway impairment in a murine model of multiple microinfarcts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28188218 DOI: 10.1523/JNEUROSCI.2112-16.2017  0.264
2020 Mestre H, Mori Y, Nedergaard M. The Brain's Glymphatic System: Current Controversies. Trends in Neurosciences. PMID 32423764 DOI: 10.1016/j.tins.2020.04.003  0.264
2023 Kim D, Gan Y, Nedergaard M, Kelley DH, Tithof J. Image Analysis Techniques for In Vivo Quantification of Cerebrospinal Fluid Flow. Biorxiv : the Preprint Server For Biology. PMID 37546970 DOI: 10.1101/2023.07.20.549937  0.263
2015 Lee H, Xie L, Yu M, Kang H, Feng T, Deane R, Logan J, Nedergaard M, Benveniste H. The Effect of Body Posture on Brain Glymphatic Transport. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11034-44. PMID 26245965 DOI: 10.1523/Jneurosci.1625-15.2015  0.261
2023 Agarwal N, Lewis LD, Hirschler L, Rivera LR, Naganawa S, Levendovszky SR, Ringstad G, Klarica M, Wardlaw J, Iadecola C, Hawkes C, Carare RO, Wells J, Bakker ENTP, Kurtcuoglu V, ... ... Nedergaard M, et al. Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 "ISMRM Imaging Neurofluids Study group" Workshop in Rome. Journal of Magnetic Resonance Imaging : Jmri. PMID 37141288 DOI: 10.1002/jmri.28759  0.261
2016 Lundgaard I, Lu ML, Yang E, Peng W, Mestre H, Hitomi E, Deane R, Nedergaard M. Glymphatic clearance controls state-dependent changes in brain lactate concentration. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27481936 DOI: 10.1177/0271678X16661202  0.26
2015 Ratner V, Zhu L, Kolesov I, Nedergaard M, Benveniste H, Tannenbaum A. Optimal-mass-transfer-based estimation of glymphatic transport in living brain. Proceedings of Spie--the International Society For Optical Engineering. 9413. PMID 26877579 DOI: 10.1117/12.2076289  0.259
2012 O'Donnell J, Zeppenfeld D, McConnell E, Pena S, Nedergaard M. Norepinephrine: a neuromodulator that boosts the function of multiple cell types to optimize CNS performance. Neurochemical Research. 37: 2496-512. PMID 22717696 DOI: 10.1007/s11064-012-0818-x  0.258
2014 Kress BT, Iliff JJ, Xia M, Wang M, Wei HS, Zeppenfeld D, Xie L, Kang H, Xu Q, Liew JA, Plog BA, Ding F, Deane R, Nedergaard M. Impairment of paravascular clearance pathways in the aging brain. Annals of Neurology. 76: 845-61. PMID 25204284 DOI: 10.1002/ana.24271  0.258
2014 Thrane AS, Rangroo Thrane V, Nedergaard M. Drowning stars: reassessing the role of astrocytes in brain edema. Trends in Neurosciences. 37: 620-8. PMID 25236348 DOI: 10.1016/j.tins.2014.08.010  0.256
2019 Ramos M, Burdon Bechet N, Battistella R, Pavan C, Xavier ALR, Nedergaard M, Lundgaard I. Cisterna Magna Injection in Rats to Study Glymphatic Function. Methods in Molecular Biology (Clifton, N.J.). 1938: 97-104. PMID 30617975 DOI: 10.1007/978-1-4939-9068-9_7  0.254
2017 Benveniste H, Lee H, Ding F, Sun Q, Al-Bizri E, Makaryus R, Probst S, Nedergaard M, Stein EA, Lu H. Anesthesia with Dexmedetomidine and Low-dose Isoflurane Increases Solute Transport via the Glymphatic Pathway in Rat Brain When Compared with High-dose Isoflurane. Anesthesiology. PMID 28938276 DOI: 10.1097/Aln.0000000000001888  0.253
2015 Verkhratsky A, Nedergaard M, Hertz L. Why are astrocytes important? Neurochemical Research. 40: 389-401. PMID 25113122 DOI: 10.1007/s11064-014-1403-2  0.253
2007 Iadecola C, Nedergaard M. Glial regulation of the cerebral microvasculature. Nature Neuroscience. 10: 1369-76. PMID 17965657 DOI: 10.1038/Nn2003  0.253
2023 Raicevic N, Forer JM, Ladrón-de-Guevara A, Du T, Nedergaard M, Kelley DH, Boster K. Sizes and shapes of perivascular spaces surrounding murine pial arteries. Fluids and Barriers of the Cns. 20: 56. PMID 37461047 DOI: 10.1186/s12987-023-00454-z  0.252
2018 Xavier ALR, Hauglund NL, von Holstein-Rathlou S, Li Q, Sanggaard S, Lou N, Lundgaard I, Nedergaard M. Cannula Implantation into the Cisterna Magna of Rodents. Journal of Visualized Experiments : Jove. PMID 29889209 DOI: 10.3791/57378  0.252
2020 Reeves BC, Karimy JK, Kundishora AJ, Mestre H, Cerci HM, Matouk C, Alper SL, Lundgaard I, Nedergaard M, Kahle KT. Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus. Trends in Molecular Medicine. PMID 31959516 DOI: 10.1016/j.molmed.2019.11.008  0.252
2019 Munk AS, Wang W, Bèchet NB, Eltanahy AM, Cheng AX, Sigurdsson B, Benraiss A, Mäe MA, Kress BT, Kelley DH, Betsholtz C, Møllgård K, Meissner A, Nedergaard M, Lundgaard I. PDGF-B Is Required for Development of the Glymphatic System. Cell Reports. 26: 2955-2969.e3. PMID 30865886 DOI: 10.1016/J.Celrep.2019.02.050  0.251
2006 Takano T, Tian GF, Peng W, Lou N, Libionka W, Han X, Nedergaard M. Astrocyte-mediated control of cerebral blood flow. Nature Neuroscience. 9: 260-7. PMID 16388306 DOI: 10.1038/nn1623  0.249
2018 Brown R, Benveniste H, Black SE, Charpak S, Dichgans M, Joutel A, Nedergaard M, Smith KJ, Zlokovic BV, Wardlaw JM. Understanding the role of the perivascular space in cerebral small vessel disease. Cardiovascular Research. PMID 29726891 DOI: 10.1093/Cvr/Cvy113  0.249
2021 Benveniste H, Nedergaard M. Cerebral small vessel disease: A glymphopathy? Current Opinion in Neurobiology. 72: 15-21. PMID 34407477 DOI: 10.1016/j.conb.2021.07.006  0.246
2023 Ge GR, Rolland JP, Song W, Nedergaard M, Parker KJ. Fluid compartments influence elastography of the aging mouse brain. Physics in Medicine and Biology. PMID 36996842 DOI: 10.1088/1361-6560/acc922  0.245
2013 Rangroo Thrane V, Thrane AS, Plog BA, Thiyagarajan M, Iliff JJ, Deane R, Nagelhus EA, Nedergaard M. Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain. Scientific Reports. 3: 2582. PMID 24002448 DOI: 10.1038/srep02582  0.242
2022 Lohela TJ, Lilius TO, Nedergaard M. The glymphatic system: implications for drugs for central nervous system diseases. Nature Reviews. Drug Discovery. PMID 35948785 DOI: 10.1038/s41573-022-00500-9  0.241
2023 Gan Y, Holstein-Rønsbo S, Nedergaard M, Boster KAS, Thomas JH, Kelley DH. Perivascular pumping of cerebrospinal fluid in the brain with a valve mechanism. Journal of the Royal Society, Interface. 20: 20230288. PMID 37727070 DOI: 10.1098/rsif.2023.0288  0.241
2001 Cotrina ML, Gao Q, Lin JH, Nedergaard M. Expression and function of astrocytic gap junctions in aging. Brain Research. 901: 55-61. PMID 11368950 DOI: 10.1016/S0006-8993(01)02258-2  0.241
2003 Simard M, Arcuino G, Takano T, Liu QS, Nedergaard M. Signaling at the gliovascular interface. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9254-62. PMID 14534260  0.241
2023 Møllgård K, Beinlich FRM, Kusk P, Miyakoshi LM, Delle C, Plá V, Hauglund NL, Esmail T, Rasmussen MK, Gomolka RS, Mori Y, Nedergaard M. A mesothelium divides the subarachnoid space into functional compartments. Science (New York, N.Y.). 379: 84-88. PMID 36603070 DOI: 10.1126/science.adc8810  0.24
2004 Ballabh P, Braun A, Nedergaard M. The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiology of Disease. 16: 1-13. PMID 15207256 DOI: 10.1016/j.nbd.2003.12.016  0.239
2018 Plog BA, Mestre H, Olveda GE, Sweeney AM, Kenney HM, Cove A, Dholakia KY, Tithof J, Nevins TD, Lundgaard I, Du T, Kelley DH, Nedergaard M. Transcranial optical imaging reveals a pathway for optimizing the delivery of immunotherapeutics to the brain. Jci Insight. 3. PMID 30333324 DOI: 10.1172/Jci.Insight.120922  0.239
2006 Tian GF, Takano T, Lin JH, Wang X, Bekar L, Nedergaard M. Imaging of cortical astrocytes using 2-photon laser scanning microscopy in the intact mouse brain. Advanced Drug Delivery Reviews. 58: 773-87. PMID 17045697 DOI: 10.1016/j.addr.2006.07.001  0.239
2019 Tithof J, Kelley DH, Mestre H, Nedergaard M, Thomas JH. Hydraulic resistance of periarterial spaces in the brain. Fluids and Barriers of the Cns. 16: 19. PMID 31217012 DOI: 10.1186/S12987-019-0140-Y  0.237
2014 Iliff JJ, Chen MJ, Plog BA, Zeppenfeld DM, Soltero M, Yang L, Singh I, Deane R, Nedergaard M. Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16180-93. PMID 25471560 DOI: 10.1523/JNEUROSCI.3020-14.2014  0.236
2015 O'Donnell J, Ding F, Nedergaard M. Distinct functional states of astrocytes during sleep and wakefulness: Is norepinephrine the master regulator? Current Sleep Medicine Reports. 1: 1-8. PMID 26618103 DOI: 10.1007/s40675-014-0004-6  0.236
2020 Wardlaw JM, Benveniste H, Nedergaard M, Zlokovic BV, Mestre H, Lee H, Doubal FN, Brown R, Ramirez J, MacIntosh BJ, Tannenbaum A, Ballerini L, Rungta RL, Boido D, Sweeney M, et al. Perivascular spaces in the brain: anatomy, physiology and pathology. Nature Reviews. Neurology. PMID 32094487 DOI: 10.1038/S41582-020-0312-Z  0.235
2014 Petraglia AL, Plog BA, Dayawansa S, Dashnaw ML, Czerniecka K, Walker CT, Chen M, Hyrien O, Iliff JJ, Deane R, Huang JH, Nedergaard M. The pathophysiology underlying repetitive mild traumatic brain injury in a novel mouse model of chronic traumatic encephalopathy. Surgical Neurology International. 5: 184. PMID 25593768 DOI: 10.4103/2152-7806.147566  0.235
2017 Oberheim Bush NA, Nedergaard M. Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain? Neurochemical Research. PMID 28822066 DOI: 10.1007/s11064-017-2363-0  0.235
2015 Jessen NA, Munk AS, Lundgaard I, Nedergaard M. The Glymphatic System: A Beginner's Guide. Neurochemical Research. PMID 25947369 DOI: 10.1007/s11064-015-1581-6  0.235
2023 Lilius TO, Mortensen KN, Deville C, Lohela TJ, Stæger FF, Sigurdsson B, Fiordaliso EM, Rosenholm M, Kamphuis C, Beekman FJ, Jensen AI, Nedergaard M. Glymphatic-assisted perivascular brain delivery of intrathecal small gold nanoparticles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 355: 135-148. PMID 36731802 DOI: 10.1016/j.jconrel.2023.01.054  0.234
2023 Mathiesen BK, Miyakoshi LM, Cederroth CR, Tserga E, Versteegh C, Bork PAR, Hauglund NL, Gomolka RS, Mori Y, Edvall NK, Rouse S, Møllgård K, Holt JR, Nedergaard M, Canlon B. Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice. Science Translational Medicine. 15: eabq3916. PMID 37379370 DOI: 10.1126/scitranslmed.abq3916  0.233
2022 Liu G, Ladrón-de-Guevara A, Izhiman Y, Nedergaard M, Du T. Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies. Fluids and Barriers of the Cns. 19: 101. PMID 36522656 DOI: 10.1186/s12987-022-00382-4  0.231
2017 Lee H, Mortensen K, Sanggaard S, Koch P, Brunner H, Quistorff B, Nedergaard M, Benveniste H. Quantitative Gd-DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA-SPGR at 9.4T. Magnetic Resonance in Medicine. PMID 28627037 DOI: 10.1002/mrm.26779  0.231
2022 Ge GR, Song W, Nedergaard M, Rolland JP, Parker KJ. Theory of sleep/wake cycles affecting brain elastography. Physics in Medicine and Biology. PMID 36317278 DOI: 10.1088/1361-6560/ac9e40  0.231
2020 Liu G, Mestre H, Sweeney AM, Sun Q, Weikop P, Du T, Nedergaard M. Direct Measurement of Cerebrospinal Fluid Production in Mice. Cell Reports. 33: 108524. PMID 33357428 DOI: 10.1016/j.celrep.2020.108524  0.231
2005 Nedergaard M, Dirnagl U. Role of glial cells in cerebral ischemia. Glia. 50: 281-6. PMID 15846807 DOI: 10.1002/Glia.20205  0.23
2015 Plog BA, Dashnaw ML, Hitomi E, Peng W, Liao Y, Lou N, Deane R, Nedergaard M. Biomarkers of traumatic injury are transported from brain to blood via the glymphatic system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 518-26. PMID 25589747 DOI: 10.1523/JNEUROSCI.3742-14.2015  0.227
1994 Makar TK, Nedergaard M, Preuss A, Hertz L, Cooper AJ. Glutamine transaminase K and omega-amidase activities in primary cultures of astrocytes and neurons and in embryonic chick forebrain: marked induction of brain glutamine transaminase K at time of hatching. Journal of Neurochemistry. 62: 1983-8. PMID 8158144  0.224
1994 Nedergaard M. Direct signaling from astrocytes to neurons in cultures of mammalian brain cells. Science (New York, N.Y.). 263: 1768-71. PMID 8134839  0.223
2014 Takano T, He W, Han X, Wang F, Xu Q, Wang X, Oberheim Bush NA, Cruz N, Dienel GA, Nedergaard M. Rapid manifestation of reactive astrogliosis in acute hippocampal brain slices. Glia. 62: 78-95. PMID 24272704 DOI: 10.1002/glia.22588  0.222
2003 Ransom B, Behar T, Nedergaard M. New roles for astrocytes (stars at last). Trends in Neurosciences. 26: 520-2. PMID 14522143 DOI: 10.1016/j.tins.2003.08.006  0.22
2022 Lopes van den Broek S, Shalgunov V, García Vázquez R, Beschorner N, Bidesi NSR, Nedergaard M, Knudsen GM, Sehlin D, Syvänen S, Herth MM. Pretargeted Imaging beyond the Blood-Brain Barrier-Utopia or Feasible? Pharmaceuticals (Basel, Switzerland). 15. PMID 36297303 DOI: 10.3390/ph15101191  0.219
2022 Bohr T, Hjorth PG, Holst SC, Hrabětová S, Kiviniemi V, Lilius T, Lundgaard I, Mardal KA, Martens EA, Mori Y, Nägerl UV, Nicholson C, Tannenbaum A, Thomas JH, Tithof J, ... ... Nedergaard M, et al. The glymphatic system: Current understanding and modeling. Iscience. 25: 104987. PMID 36093063 DOI: 10.1016/j.isci.2022.104987  0.219
2022 Tithof J, Boster KAS, Bork PAR, Nedergaard M, Thomas JH, Kelley DH. A network model of glymphatic flow under different experimentally-motivated parametric scenarios. Iscience. 25: 104258. PMID 35521514 DOI: 10.1016/j.isci.2022.104258  0.219
2017 DiNuzzo M, Nedergaard M. Brain energetics during the sleep-wake cycle. Current Opinion in Neurobiology. 47: 65-72. PMID 29024871 DOI: 10.1016/j.conb.2017.09.010  0.218
2019 Nygaard Mortensen K, Sanggaard S, Mestre H, Lee H, Kostrikov S, Xavier ALR, Gjedde A, Benveniste H, Nedergaard M. Impaired Glymphatic Transport in Spontaneously Hypertensive Rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31209176 DOI: 10.1523/JNEUROSCI.1974-18.2019  0.218
1999 Zhang W, Couldwell WT, Simard MF, Song H, Lin JH, Nedergaard M. Direct gap junction communication between malignant glioma cells and astrocytes. Cancer Research. 59: 1994-2003. PMID 10213512  0.216
2022 Persson NDÅ, Uusalo P, Nedergaard M, Lohela TJ, Lilius TO. Could dexmedetomidine be repurposed as a glymphatic enhancer? Trends in Pharmacological Sciences. 43: 1030-1040. PMID 36280451 DOI: 10.1016/j.tips.2022.09.007  0.216
2012 Verkhratsky A, Sofroniew MV, Messing A, deLanerolle NC, Rempe D, Rodríguez JJ, Nedergaard M. Neurological diseases as primary gliopathies: a reassessment of neurocentrism. Asn Neuro. 4. PMID 22339481 DOI: 10.1042/An20120010  0.215
2011 Thrane AS, Rappold PM, Fujita T, Torres A, Bekar LK, Takano T, Peng W, Wang F, Rangroo Thrane V, Enger R, Haj-Yasein NN, Skare Ø, Holen T, Klungland A, Ottersen OP, ... Nedergaard M, et al. Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema. Proceedings of the National Academy of Sciences of the United States of America. 108: 846-51. PMID 21187412 DOI: 10.1073/pnas.1015217108  0.214
2015 Kiviniemi V, Wang X, Korhonen V, Keinänen T, Tuovinen T, Autio J, LeVan P, Keilholz S, Zang YF, Hennig J, Nedergaard M. Ultra-fast magnetic resonance encephalography of physiological brain activity - Glymphatic pulsation mechanisms? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26690495 DOI: 10.1177/0271678X15622047  0.214
2013 Sun W, McConnell E, Pare JF, Xu Q, Chen M, Peng W, Lovatt D, Han X, Smith Y, Nedergaard M. Glutamate-dependent neuroglial calcium signaling differs between young and adult brain. Science (New York, N.Y.). 339: 197-200. PMID 23307741 DOI: 10.1126/science.1226740  0.214
2021 Stanton EH, Persson NDÅ, Gomolka RS, Lilius T, Sigurðsson B, Lee H, Xavier ALR, Benveniste H, Nedergaard M, Mori Y. Mapping of CSF transport using high spatiotemporal resolution dynamic contrast-enhanced MRI in mice: Effect of anesthesia. Magnetic Resonance in Medicine. PMID 33426699 DOI: 10.1002/mrm.28645  0.213
2020 Kananen J, Helakari H, Korhonen V, Huotari N, Järvelä M, Raitamaa L, Raatikainen V, Rajna Z, Tuovinen T, Nedergaard M, Jacobs J, LeVan P, Ansakorpi H, Kiviniemi V. Respiratory-related brain pulsations are increased in epilepsy-a two-centre functional MRI study. Brain Communications. 2: fcaa076. PMID 32954328 DOI: 10.1093/braincomms/fcaa076  0.211
2008 Oberheim NA, Tian GF, Han X, Peng W, Takano T, Ransom B, Nedergaard M. Loss of astrocytic domain organization in the epileptic brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3264-76. PMID 18367594 DOI: 10.1523/JNEUROSCI.4980-07.2008  0.211
2018 Verkhratsky A, Nedergaard M. Physiology of Astroglia. Physiological Reviews. 98: 239-389. PMID 29351512 DOI: 10.1152/physrev.00042.2016  0.21
1998 Cotrina ML, Kang J, Lin JH, Bueno E, Hansen TW, He L, Liu Y, Nedergaard M. Astrocytic gap junctions remain open during ischemic conditions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2520-37. PMID 9502812  0.21
2020 Li Q, Aalling NN, Förstera B, Ertürk A, Nedergaard M, Møllgård K, Xavier ALR. Aquaporin 1 and the Na/K/2Cl cotransporter 1 are present in the leptomeningeal vasculature of the adult rodent central nervous system. Fluids and Barriers of the Cns. 17: 15. PMID 32046744 DOI: 10.1186/S12987-020-0176-Z  0.209
2008 Neuwelt E, Abbott NJ, Abrey L, Banks WA, Blakley B, Davis T, Engelhardt B, Grammas P, Nedergaard M, Nutt J, Pardridge W, Rosenberg GA, Smith Q, Drewes LR. Strategies to advance translational research into brain barriers. The Lancet. Neurology. 7: 84-96. PMID 18093565 DOI: 10.1016/S1474-4422(07)70326-5  0.207
2016 Peng W, Achariyar TM, Li B, Liao Y, Mestre H, Hitomi E, Regan S, Kasper T, Peng S, Ding F, Benveniste H, Nedergaard M, Deane R. Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease. Neurobiology of Disease. PMID 27234656 DOI: 10.1016/J.Nbd.2016.05.015  0.207
2012 Nedergaard M, Verkhratsky A. Artifact versus reality--how astrocytes contribute to synaptic events. Glia. 60: 1013-23. PMID 22228580 DOI: 10.1002/glia.22288  0.207
2013 Nedergaard M. Neuroscience. Garbage truck of the brain. Science (New York, N.Y.). 340: 1529-30. PMID 23812703 DOI: 10.1126/science.1240514  0.207
2019 DiNuzzo M, Walls AB, Öz G, Seaquist ER, Waagepetersen HS, Bak LK, Nedergaard M, Schousboe A. State-Dependent Changes in Brain Glycogen Metabolism. Advances in Neurobiology. 23: 269-309. PMID 31667812 DOI: 10.1007/978-3-030-27480-1_9  0.206
2002 Cotrina ML, Nedergaard M. Astrocytes in the aging brain. Journal of Neuroscience Research. 67: 1-10. PMID 11754075 DOI: 10.1002/jnr.10121  0.205
2023 Wang X, Delle C, Peng W, Plá V, Giannetto M, Kusk P, Sigurdsson B, Sakurai S, Sweeney A, Sun Q, Du T, Libby RT, Nedergaard M. Age- and glaucoma-induced changes to the ocular glymphatic system. Neurobiology of Disease. 188: 106322. PMID 37832797 DOI: 10.1016/j.nbd.2023.106322  0.205
1984 Nedergaard M, Astrup J, Klinken L. Cell density and cortex thickness in the border zone surrounding old infarcts in the human brain. Stroke; a Journal of Cerebral Circulation. 15: 1033-9. PMID 6209831  0.205
2015 Makaryus R, Lee H, Feng T, Park JH, Nedergaard M, Jacob Z, Enikolopov G, Benveniste H. Brain Maturation in Neonatal Rodents Is Impeded by Sevoflurane Anesthesia. Anesthesiology. PMID 26181336 DOI: 10.1097/Aln.0000000000000762  0.205
2017 Louveau A, Plog BA, Antila S, Alitalo K, Nedergaard M, Kipnis J. Understanding the functions and relationships of the glymphatic system and meningeal lymphatics. The Journal of Clinical Investigation. 127: 3210-3219. PMID 28862640 DOI: 10.1172/Jci90603  0.205
2019 Lilius TO, Blomqvist K, Hauglund NL, Liu G, Stæger FF, Bærentzen S, Du T, Ahlström F, Backman JT, Kalso EA, Rauhala PV, Nedergaard M. Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31067483 DOI: 10.1016/j.jconrel.2019.05.005  0.205
2022 Kananen J, Järvelä M, Korhonen V, Tuovinen T, Huotari N, Raitamaa L, Helakari H, Väyrynen T, Raatikainen V, Nedergaard M, Ansakorpi H, Jacobs J, LeVan P, Kiviniemi V. Increased interictal synchronicity of respiratory related brain pulsations in epilepsy. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X221099703. PMID 35570730 DOI: 10.1177/0271678X221099703  0.203
2023 Sigurdsson B, Hauglund NL, Lilius TO, Mogensen FL, Mortensen KN, Beschorner N, Klinger L, Bærentzen SL, Rosenholm MP, Shalgunov V, Herth M, Mori Y, Nedergaard M. A SPECT-based method for dynamic imaging of the glymphatic system in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X231156982. PMID 36809165 DOI: 10.1177/0271678X231156982  0.203
2013 Iliff JJ, Wang M, Zeppenfeld DM, Venkataraman A, Plog BA, Liao Y, Deane R, Nedergaard M. Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18190-9. PMID 24227727 DOI: 10.1523/JNEUROSCI.1592-13.2013  0.203
2015 Lundgaard I, Li B, Xie L, Kang H, Sanggaard S, Haswell JD, Sun W, Goldman S, Blekot S, Nielsen M, Takano T, Deane R, Nedergaard M. Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism. Nature Communications. 6: 6807. PMID 25904018 DOI: 10.1038/ncomms7807  0.202
2019 Grutzendler J, Nedergaard M. Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas. Trends in Neurosciences. PMID 31255380 DOI: 10.1016/j.tins.2019.05.009  0.2
2021 Raghunandan A, Ladron-de-Guevara A, Tithof J, Mestre H, Du T, Nedergaard M, Thomas JH, Kelley DH. Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection. Elife. 10. PMID 33687330 DOI: 10.7554/eLife.65958  0.2
2022 Ladrón-de-Guevara A, Shang JK, Nedergaard M, Kelley DH. Perivascular pumping in the mouse brain: Improved boundary conditions reconcile theory, simulation, and experiment. Journal of Theoretical Biology. 542: 111103. PMID 35339513 DOI: 10.1016/j.jtbi.2022.111103  0.2
2010 Kimelberg HK, Nedergaard M. Functions of astrocytes and their potential as therapeutic targets. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 7: 338-53. PMID 20880499 DOI: 10.1016/j.nurt.2010.07.006  0.2
2018 Cai R, Pan C, Ghasemigharagoz A, Todorov MI, Förstera B, Zhao S, Bhatia HS, Parra-Damas A, Mrowka L, Theodorou D, Rempfler M, Xavier ALR, Kress BT, Benakis C, Steinke H, ... ... Nedergaard M, et al. Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections. Nature Neuroscience. PMID 30598527 DOI: 10.1038/S41593-018-0301-3  0.199
2020 Stæger FF, Mortensen KN, Nielsen MSN, Sigurdsson B, Kaufmann LK, Hirase H, Nedergaard M. A three-dimensional, population-based average of the C57BL/6 mouse brain from DAPI-stained coronal slices. Scientific Data. 7: 235. PMID 32661243 DOI: 10.1038/s41597-020-0570-z  0.199
2021 Monai H, Koketsu S, Shinohara Y, Ueki T, Kusk P, Hauglund NL, Samson AJ, Nedergaard M, Hirase H. Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization. Scientific Reports. 11: 8150. PMID 33854148 DOI: 10.1038/s41598-021-87609-w  0.198
2023 Plá V, Bitsika S, Giannetto M, Ladron-de-Guevara A, Gahn-Martinez D, Mori Y, Nedergaard M, Møllgård K. Structural characterization of SLYM - a 4 meningeal membrane. Biorxiv : the Preprint Server For Biology. PMID 37961461 DOI: 10.1101/2023.10.20.563351  0.198
2022 Helakari H, Korhonen V, Holst SC, Piispala J, Kallio M, Väyrynen T, Huotari N, Raitamaa L, Tuunanen J, Kananen J, Järvelä M, Tuovinen T, Raatikainen V, Borchardt V, Kinnunen H, ... Nedergaard M, et al. Human NREM Sleep Promotes Brain-Wide Vasomotor and Respiratory Pulsations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35135852 DOI: 10.1523/JNEUROSCI.0934-21.2022  0.197
2020 Ulv Larsen SM, Landolt HP, Berger W, Nedergaard M, Knudsen GM, Holst SC. Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep. Plos Biology. 18: e3000623. PMID 32369477 DOI: 10.1371/journal.pbio.3000623  0.196
2023 Ozawa K, Nagao M, Konno A, Iwai Y, Vittani M, Kusk P, Mishima T, Hirai H, Nedergaard M, Hirase H. Astrocytic GPCR-Induced Ca Signaling Is Not Causally Related to Local Cerebral Blood Flow Changes. International Journal of Molecular Sciences. 24. PMID 37686396 DOI: 10.3390/ijms241713590  0.196
2008 Lin JH, Lou N, Kang N, Takano T, Hu F, Han X, Xu Q, Lovatt D, Torres A, Willecke K, Yang J, Kang J, Nedergaard M. A central role of connexin 43 in hypoxic preconditioning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 681-95. PMID 18199768 DOI: 10.1523/JNEUROSCI.3827-07.2008  0.195
2019 Zhou S, Giannetto M, DeCourcey J, Kang H, Kang N, Li Y, Zheng S, Zhao H, Simmons WR, Wei HS, Bodine DM, Low PS, Nedergaard M, Wan J. Oxygen tension-mediated erythrocyte membrane interactions regulate cerebral capillary hyperemia. Science Advances. 5: eaaw4466. PMID 31149638 DOI: 10.1126/Sciadv.Aaw4466  0.195
2020 Kounda S, Elkin R, Nadeem S, Xue Y, Constantinou S, Sanggaard S, Liu X, Monte B, Xu F, Van Nostrand W, Nedergaard M, Lee H, Wardlaw J, Benveniste H, Tannenbaum A. Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System. Scientific Reports. 10: 1990. PMID 32029859 DOI: 10.1038/S41598-020-59045-9  0.194
1988 Hansen AJ, Nedergaard M. Brain ion homeostasis in cerebral ischemia. Neurochemical Pathology. 9: 195-209. PMID 3247069 DOI: 10.1007/BF03160362  0.193
2020 Karimy JK, Reeves BC, Damisah E, Duy PQ, Antwi P, David W, Wang K, Schiff SJ, Limbrick DD, Alper SL, Warf BC, Nedergaard M, Simard JM, Kahle KT. Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets. Nature Reviews. Neurology. PMID 32152460 DOI: 10.1038/S41582-020-0321-Y  0.192
2023 Bork PAR, Ladrón-de-Guevara A, Christensen AH, Jensen KH, Nedergaard M, Bohr T. Astrocyte endfeet may theoretically act as valves to convert pressure oscillations to glymphatic flow. Journal of the Royal Society, Interface. 20: 20230050. PMID 37434503 DOI: 10.1098/rsif.2023.0050  0.192
2022 Wostyn P, Mader TH, Gibson CR, Nedergaard M. Does Long-Duration Exposure to Microgravity Lead to Dysregulation of the Brain and Ocular Glymphatic Systems? Eye and Brain. 14: 49-58. PMID 35546965 DOI: 10.2147/EB.S354710  0.191
2012 Bekar LK, Wei HS, Nedergaard M. The locus coeruleus-norepinephrine network optimizes coupling of cerebral blood volume with oxygen demand. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 2135-45. PMID 22872230 DOI: 10.1038/jcbfm.2012.115  0.191
2009 Wang X, Takano T, Nedergaard M. Astrocytic calcium signaling: mechanism and implications for functional brain imaging. Methods in Molecular Biology (Clifton, N.J.). 489: 93-109. PMID 18839089 DOI: 10.1007/978-1-59745-543-5_5  0.19
2006 El-Khoury N, Braun A, Hu F, Pandey M, Nedergaard M, Lagamma EF, Ballabh P. Astrocyte end-feet in germinal matrix, cerebral cortex, and white matter in developing infants. Pediatric Research. 59: 673-9. PMID 16627880 DOI: 10.1203/01.pdr.0000214975.85311.9c  0.19
2023 Plá V, Bitsika S, Giannetto MJ, Ladron-de-Guevara A, Gahn-Martinez D, Mori Y, Nedergaard M, Møllgård K. Structural characterization of SLYM-a 4th meningeal membrane. Fluids and Barriers of the Cns. 20: 93. PMID 38098084 DOI: 10.1186/s12987-023-00500-w  0.19
2023 Plá V, Bitsika S, Giannetto M, Ladron-de-Guevara A, Gahn-Martinez D, Mori Y, Nedergaard M, Møllgård K. Structural characterization of SLYM - a 4th meningeal membrane. Research Square. PMID 37961391 DOI: 10.21203/rs.3.rs-3500436/v1  0.19
2003 Anderson CM, Nedergaard M. Astrocyte-mediated control of cerebral microcirculation. Trends in Neurosciences. 26: 340-4; author reply . PMID 12850427 DOI: 10.1016/S0166-2236(03)00141-3  0.189
2014 Petraglia AL, Plog BA, Dayawansa S, Chen M, Dashnaw ML, Czerniecka K, Walker CT, Viterise T, Hyrien O, Iliff JJ, Deane R, Nedergaard M, Huang JH. The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: a novel mouse model of chronic traumatic encephalopathy. Journal of Neurotrauma. 31: 1211-24. PMID 24766454 DOI: 10.1089/Neu.2013.3255  0.189
2023 Parka A, Degel C, Dreyer J, Richter U, Hall B, Bastlund JF, Laursen B, Nedergaard M, Sotty F, Botta P. Early impairments of visually-driven neuronal ensemble dynamics in the rTg4510 tauopathy mouse model. Neurobiology of Disease. 178: 106012. PMID 36696792 DOI: 10.1016/j.nbd.2023.106012  0.189
2015 Xavier AL, Lima FR, Nedergaard M, Menezes JR. Ontogeny of CX3CR1-EGFP expressing cells unveil microglia as an integral component of the postnatal subventricular zone. Frontiers in Cellular Neuroscience. 9: 37. PMID 25741237 DOI: 10.3389/fncel.2015.00037  0.189
2019 Koundal S, Liu X, Sanggaard S, Mortensen K, Wardlaw J, Nedergaard M, Benveniste H, Lee H. Brain morphometry and longitudinal relaxation time of spontaneously hypertensive rats (SHR) in early and intermediate stages of hypertension investigated by 3D VFA-SPGR MRI. Neuroscience. PMID 30690138 DOI: 10.1016/j.neuroscience.2019.01.030  0.189
2012 Enger R, Gundersen GA, Haj-Yasein NN, Eilert-Olsen M, Thoren AE, Vindedal GF, Petersen PH, Skare Ø, Nedergaard M, Ottersen OP, Nagelhus EA. Molecular scaffolds underpinning macroglial polarization: an analysis of retinal Müller cells and brain astrocytes in mouse. Glia. 60: 2018-26. PMID 22987438 DOI: 10.1002/Glia.22416  0.188
2017 Achariyar TM, Li B, Peng W, Verghese PB, Shi Y, McConnell E, Benraiss A, Kasper T, Song W, Takano T, Holtzman DM, Nedergaard M, Deane R. Erratum to: Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation. Molecular Neurodegeneration. 12: 3. PMID 28081701 DOI: 10.1186/s13024-016-0147-7  0.188
2013 Ding F, O'Donnell J, Thrane AS, Zeppenfeld D, Kang H, Xie L, Wang F, Nedergaard M. α1-Adrenergic receptors mediate coordinated Ca2+ signaling of cortical astrocytes in awake, behaving mice. Cell Calcium. 54: 387-94. PMID 24138901 DOI: 10.1016/j.ceca.2013.09.001  0.187
2008 Bekar LK, He W, Nedergaard M. Locus coeruleus alpha-adrenergic-mediated activation of cortical astrocytes in vivo. Cerebral Cortex (New York, N.Y. : 1991). 18: 2789-95. PMID 18372288 DOI: 10.1093/cercor/bhn040  0.187
2014 Cotrina ML, Chen M, Han X, Iliff J, Ren Z, Sun W, Hagemann T, Goldman J, Messing A, Nedergaard M. Effects of traumatic brain injury on reactive astrogliosis and seizures in mouse models of Alexander disease. Brain Research. 1582: 211-9. PMID 25069089 DOI: 10.1016/J.Brainres.2014.07.029  0.187
2022 Wostyn P, Mader TH, Gibson CR, Nedergaard M. The effect of long-duration spaceflight on perivascular spaces within the brain. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207724119. PMID 35858378 DOI: 10.1073/pnas.2207724119  0.187
2020 Hauglund NL, Kusk P, Kornum BR, Nedergaard M. Meningeal lymphangiogenesis and enhanced glymphatic activity in mice with chronically implanted EEG electrodes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32047056 DOI: 10.1523/JNEUROSCI.2223-19.2020  0.186
2006 Wang X, Lou N, Xu Q, Tian GF, Peng WG, Han X, Kang J, Takano T, Nedergaard M. Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo. Nature Neuroscience. 9: 816-23. PMID 16699507 DOI: 10.1038/nn1703  0.186
2007 Takano T, Han X, Deane R, Zlokovic B, Nedergaard M. Two-photon imaging of astrocytic Ca2+ signaling and the microvasculature in experimental mice models of Alzheimer's disease. Annals of the New York Academy of Sciences. 1097: 40-50. PMID 17413008 DOI: 10.1196/Annals.1379.004  0.185
2012 Wang F, Xu Q, Wang W, Takano T, Nedergaard M. Bergmann glia modulate cerebellar Purkinje cell bistability via Ca2+-dependent K+ uptake. Proceedings of the National Academy of Sciences of the United States of America. 109: 7911-6. PMID 22547829 DOI: 10.1073/pnas.1120380109  0.185
2007 Dermietzel R, Spray DC, Nedergaard M. Introduction: The Blood-Brain Barrier: An Integrated Concept Blood-Brain Barriers: From Ontogeny to Artificial Interfaces. 1: 1-8. DOI: 10.1002/9783527611225.ch  0.182
2015 McConnell ED, Wei HS, Reitz KM, Kang H, Takano T, Vates GE, Nedergaard M. Cerebral microcirculatory failure after subarachnoid hemorrhage is reversed by hyaluronidase. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661183 DOI: 10.1177/0271678X15608389  0.181
2013 Ren Z, Iliff JJ, Yang L, Yang J, Chen X, Chen MJ, Giese RN, Wang B, Shi X, Nedergaard M. 'Hit & Run' model of closed-skull traumatic brain injury (TBI) reveals complex patterns of post-traumatic AQP4 dysregulation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 834-45. PMID 23443171 DOI: 10.1038/jcbfm.2013.30  0.18
2020 Min Rivas F, Liu J, Martell BC, Du T, Mestre H, Nedergaard M, Tithof J, Thomas JH, Kelley DH. Surface periarterial spaces of the mouse brain are open, not porous. Journal of the Royal Society, Interface. 17: 20200593. PMID 33171075 DOI: 10.1098/rsif.2020.0593  0.18
2012 Bennett MV, Garré JM, Orellana JA, Bukauskas FF, Nedergaard M, Sáez JC. Connexin and pannexin hemichannels in inflammatory responses of glia and neurons. Brain Research. 1487: 3-15. PMID 22975435 DOI: 10.1016/J.Brainres.2012.08.042  0.179
2010 Nedergaard M, Rodríguez JJ, Verkhratsky A. Glial calcium and diseases of the nervous system. Cell Calcium. 47: 140-9. PMID 20045186 DOI: 10.1016/j.ceca.2009.11.010  0.177
2012 Thrane AS, Rangroo Thrane V, Zeppenfeld D, Lou N, Xu Q, Nagelhus EA, Nedergaard M. General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex. Proceedings of the National Academy of Sciences of the United States of America. 109: 18974-9. PMID 23112168 DOI: 10.1073/pnas.1209448109  0.176
2016 Wei HS, Kang H, Rasheed ID, Zhou S, Lou N, Gershteyn A, McConnell ED, Wang Y, Richardson KE, Palmer AF, Xu C, Wan J, Nedergaard M. Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation. Neuron. PMID 27499087 DOI: 10.1016/J.Neuron.2016.07.016  0.176
2012 Cotrina ML, Nedergaard M. Brain connexins in demyelinating diseases: therapeutic potential of glial targets. Brain Research. 1487: 61-8. PMID 22789906 DOI: 10.1016/j.brainres.2012.07.003  0.176
2013 Xie L, Kang H, Xu Q, Chen MJ, Liao Y, Thiyagarajan M, O'Donnell J, Christensen DJ, Nicholson C, Iliff JJ, Takano T, Deane R, Nedergaard M. Sleep drives metabolite clearance from the adult brain. Science (New York, N.Y.). 342: 373-7. PMID 24136970 DOI: 10.1126/science.1241224  0.175
2018 Mestre H, Tithof J, Du T, Song W, Peng W, Sweeney AM, Olveda G, Thomas JH, Nedergaard M, Kelley DH. Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension. Nature Communications. 9: 4878. PMID 30451853 DOI: 10.1038/S41467-018-07318-3  0.174
1986 Nedergaard M, Vorstrup S, Astrup J. Cell density in the border zone around old small human brain infarcts. Stroke; a Journal of Cerebral Circulation. 17: 1129-37. PMID 3810711  0.174
2023 Helakari H, Järvelä M, Väyrynen T, Tuunanen J, Piispala J, Kallio M, Ebrahimi SM, Poltojainen V, Kananen J, Elabasy A, Huotari N, Raitamaa L, Tuovinen T, Korhonen V, Nedergaard M, et al. Effect of sleep deprivation and NREM sleep stage on physiological brain pulsations. Frontiers in Neuroscience. 17: 1275184. PMID 38105924 DOI: 10.3389/fnins.2023.1275184  0.173
2023 Vittani M, Knak PAG, Fukuda M, Nagao M, Wang X, Kjaerby C, Konno A, Hirai H, Nedergaard M, Hirase H. Virally induced CRISPR/Cas9-based knock-in of fluorescent albumin allows long-term visualization of cerebral circulation in infant and adult mice. Biorxiv : the Preprint Server For Biology. PMID 37503027 DOI: 10.1101/2023.07.10.548084  0.173
1988 Nedergaard M. Mechanisms of brain damage in focal cerebral ischemia. Acta Neurologica Scandinavica. 77: 81-101. PMID 3284272  0.172
2018 Kananen J, Tuovinen T, Ansakorpi H, Rytky S, Helakari H, Huotari N, Raitamaa L, Raatikainen V, Rasila A, Borchardt V, Korhonen V, LeVan P, Nedergaard M, Kiviniemi V. Altered physiological brain variation in drug-resistant epilepsy. Brain and Behavior. e01090. PMID 30112813 DOI: 10.1002/brb3.1090  0.17
2012 Chen MJ, Kress B, Han X, Moll K, Peng W, Ji RR, Nedergaard M. Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury. Glia. 60: 1660-70. PMID 22951907 DOI: 10.1002/glia.22384  0.17
1994 Makar TK, Nedergaard M, Preuss A, Gelbard AS, Perumal AS, Cooper AJ. Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain. Journal of Neurochemistry. 62: 45-53. PMID 7903354  0.17
2005 Tian GF, Azmi H, Takano T, Xu Q, Peng W, Lin J, Oberheim N, Lou N, Wang X, Zielke HR, Kang J, Nedergaard M. An astrocytic basis of epilepsy. Nature Medicine. 11: 973-81. PMID 16116433 DOI: 10.1038/nm1277  0.17
2013 Bekar LK, Nedergaard M. Is potassium a ubiquitous mediator of vasodilation in the central nervous system? Biophysical Journal. 105: 2238-9. PMID 24268135 DOI: 10.1016/j.bpj.2013.09.056  0.169
2012 Torres A, Wang F, Xu Q, Fujita T, Dobrowolski R, Willecke K, Takano T, Nedergaard M. Extracellular Ca²⁺ acts as a mediator of communication from neurons to glia. Science Signaling. 5: ra8. PMID 22275221 DOI: 10.1126/scisignal.2002160  0.168
2005 Takano T, Kang J, Jaiswal JK, Simon SM, Lin JH, Yu Y, Li Y, Yang J, Dienel G, Zielke HR, Nedergaard M. Receptor-mediated glutamate release from volume sensitive channels in astrocytes. Proceedings of the National Academy of Sciences of the United States of America. 102: 16466-71. PMID 16254051 DOI: 10.1073/Pnas.0506382102  0.167
2016 Verkhratsky A, Nedergaard M. The homeostatic astroglia emerges from evolutionary specialization of neural cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 371. PMID 27377722 DOI: 10.1098/rstb.2015.0428  0.166
2021 Rajna Z, Mattila H, Huotari N, Tuovinen T, Krüger J, Holst SC, Korhonen V, Remes AM, Seppänen T, Hennig J, Nedergaard M, Kiviniemi V. Cardiovascular brain impulses in Alzheimer's disease. Brain : a Journal of Neurology. PMID 33787890 DOI: 10.1093/brain/awab144  0.164
2005 Kang N, Xu J, Xu Q, Nedergaard M, Kang J. Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons. Journal of Neurophysiology. 94: 4121-30. PMID 16162834 DOI: 10.1152/Jn.00448.2005  0.164
2022 Shalgunov V, Lopes van den Broek S, Vang Andersen I, García Vázquez R, Raval NR, Palner M, Mori Y, Schäfer G, Herrmann B, Mikula H, Beschorner N, Nedergaard M, Syvänen S, Barz M, Moos Knudsen G, et al. Pretargeted imaging beyond the blood-brain barrier. Rsc Medicinal Chemistry. 14: 444-453. PMID 36970152 DOI: 10.1039/d2md00360k  0.163
2009 Takano T, Nedergaard M. Deciphering migraine. The Journal of Clinical Investigation. 119: 16-9. PMID 19104145 DOI: 10.1172/JCI38051  0.163
2000 Martins-Ferreira H, Nedergaard M, Nicholson C. Perspectives on spreading depression. Brain Research. Brain Research Reviews. 32: 215-34. PMID 10751672 DOI: 10.1016/S0165-0173(99)00083-1  0.163
2020 Tuovinen T, Kananen J, Rajna Z, Lieslehto J, Korhonen V, Rytty R, Mattila H, Huotari N, Raitamaa L, Helakari H, Elseoud AA, Krüger J, LeVan P, Tervonen O, Hennig J, ... ... Nedergaard M, et al. The variability of functional MRI brain signal increases in Alzheimer's disease at cardiorespiratory frequencies. Scientific Reports. 10: 21559. PMID 33298996 DOI: 10.1038/s41598-020-77984-1  0.162
2012 Takano T, Chen X, Luo F, Fujita T, Ren Z, Goldman N, Zhao Y, Markman JD, Nedergaard M. Traditional acupuncture triggers a local increase in adenosine in human subjects. The Journal of Pain : Official Journal of the American Pain Society. 13: 1215-23. PMID 23182227 DOI: 10.1016/j.jpain.2012.09.012  0.162
2008 Bekar L, Libionka W, Tian GF, Xu Q, Torres A, Wang X, Lovatt D, Williams E, Takano T, Schnermann J, Bakos R, Nedergaard M. Adenosine is crucial for deep brain stimulation-mediated attenuation of tremor. Nature Medicine. 14: 75-80. PMID 18157140 DOI: 10.1038/Nm1693  0.162
2023 Delle C, Cankar N, Digebjerg Holgersson C, Hvorup Knudsen H, Schiøler Nielsen E, Kjaerby C, Mori Y, Nedergaard M, Weikop P. Long-term high-fat diet increases glymphatic activity in the hypothalamus in mice. Scientific Reports. 13: 4137. PMID 36914703 DOI: 10.1038/s41598-023-30630-y  0.16
1987 Nedergaard M, Gjedde A, Diemer NH. Hyperglycaemia protects against neuronal injury around experimental brain infarcts. Neurological Research. 9: 241-4. PMID 2895900 DOI: 10.1080/01616412.1987.11739802  0.16
2008 Kang J, Kang N, Lovatt D, Torres A, Zhao Z, Lin J, Nedergaard M. Connexin 43 hemichannels are permeable to ATP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4702-11. PMID 18448647 DOI: 10.1523/JNEUROSCI.5048-07.2008  0.159
2015 Sreetama SC, Takano T, Nedergaard M, Simon SM, Jaiswal JK. Injured astrocytes are repaired by Synaptotagmin XI-regulated lysosome exocytosis. Cell Death and Differentiation. PMID 26450452 DOI: 10.1038/cdd.2015.124  0.159
2012 Wang M, Iliff JJ, Liao Y, Chen MJ, Shinseki MS, Venkataraman A, Cheung J, Wang W, Nedergaard M. Cognitive deficits and delayed neuronal loss in a mouse model of multiple microinfarcts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17948-60. PMID 23238711 DOI: 10.1523/JNEUROSCI.1860-12.2012  0.157
2022 Lilius TO, Rosenholm M, Klinger L, Mortensen KN, Sigurdsson B, Mogensen FL, Hauglund NL, Nielsen MSN, Rantamäki T, Nedergaard M. SPECT/CT imaging reveals CNS-wide modulation of glymphatic cerebrospinal fluid flow by systemic hypertonic saline. Iscience. 25: 105250. PMID 36274948 DOI: 10.1016/j.isci.2022.105250  0.156
2020 Mestre H, Du T, Sweeney AM, Liu G, Samson AJ, Peng W, Mortensen KN, Stæger FF, Bork PAR, Bashford L, Toro ER, Tithof J, Kelley DH, Thomas JH, Hjorth PG, ... ... Nedergaard M, et al. Cerebrospinal fluid influx drives acute ischemic tissue swelling. Science (New York, N.Y.). PMID 32001524 DOI: 10.1126/Science.Aax7171  0.156
2017 de Leon MJ, Li Y, Okamura N, Tsui WH, Saint Louis LA, Glodzik L, Osorio RS, Fortea J, Butler T, Pirraglia E, Fossati S, Kim HJ, Carare RO, Nedergaard M, Benveniste H, et al. CSF clearance in Alzheimer Disease measured with dynamic PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 28302766 DOI: 10.2967/Jnumed.116.187211  0.155
2015 Benveniste H, Hof PR, Nedergaard M, Bechter K. Modern cerebrospinal fluid flow research and Heinrich Quincke's seminal 1872 article on the distribution of cinnabar in freely moving animals. The Journal of Comparative Neurology. 523: 1748-55. PMID 25684428 DOI: 10.1002/Cne.23758  0.155
2016 Ding F, O'Donnell J, Xu Q, Kang N, Goldman N, Nedergaard M. Changes in the composition of brain interstitial ions control the sleep-wake cycle. Science (New York, N.Y.). 352: 550-5. PMID 27126038 DOI: 10.1126/science.aad4821  0.155
2014 Fields RD, Araque A, Johansen-Berg H, Lim SS, Lynch G, Nave KA, Nedergaard M, Perez R, Sejnowski T, Wake H. Glial biology in learning and cognition. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 20: 426-31. PMID 24122821 DOI: 10.1177/1073858413504465  0.154
2017 Mestre H, Kostrikov S, Mehta RI, Nedergaard M. Perivascular spaces, glymphatic dysfunction, and small vessel disease. Clinical Science (London, England : 1979). 131: 2257-2274. PMID 28798076 DOI: 10.1042/CS20160381  0.154
2015 Haydon PG, Nedergaard M. How do astrocytes participate in neural plasticity? Cold Spring Harbor Perspectives in Biology. 7: a020438. PMID 25502516 DOI: 10.1101/cshperspect.a020438  0.154
2023 Raicevic N, Forer JM, Ladron-de-Guevara A, Du T, Nedergaard M, Kelley DH, Boster KAS. Sizes and Shapes of Perivascular Spaces Surrounding Murine Pial Arteries. Research Square. PMID 36824982 DOI: 10.21203/rs.3.rs-2587250/v1  0.153
2014 Chen G, Park CK, Xie RG, Berta T, Nedergaard M, Ji RR. Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice. Brain : a Journal of Neurology. 137: 2193-209. PMID 24919967 DOI: 10.1093/Brain/Awu140  0.152
2021 Pavan C, Xavier AL, Ramos M, Fisher J, Kritsilis M, Linder A, Bentzer P, Nedergaard M, Lundgaard I. DNase treatment prevents CSF block in early experimental pneumococcal meningitis. Annals of Neurology. PMID 34397111 DOI: 10.1002/ana.26186  0.152
2013 Ji RR, Berta T, Nedergaard M. Glia and pain: is chronic pain a gliopathy? Pain. 154: S10-28. PMID 23792284 DOI: 10.1016/j.pain.2013.06.022  0.152
2012 Verkhratsky A, Pankratov Y, Lalo U, Nedergaard M. P2X receptors in neuroglia. Wiley Interdisciplinary Reviews. Membrane Transport and Signaling. 1. PMID 24349942 DOI: 10.1002/wmts.12  0.15
1988 Nedergaard M, Hansen AJ. Spreading depression is not associated with neuronal injury in the normal brain. Brain Research. 449: 395-8. PMID 3395856 DOI: 10.1016/0006-8993(88)91062-1  0.149
2015 Plog BA, Nedergaard M. Why have we not yet developed a simple blood test for TBI? Expert Review of Neurotherapeutics. 15: 465-8. PMID 25821902 DOI: 10.1586/14737175.2015.1031112  0.148
2001 Takano T, Lin JH, Arcuino G, Gao Q, Yang J, Nedergaard M. Glutamate release promotes growth of malignant gliomas. Nature Medicine. 7: 1010-5. PMID 11533703 DOI: 10.1038/nm0901-1010  0.148
2006 Anderson CM, Nedergaard M. Emerging challenges of assigning P2X7 receptor function and immunoreactivity in neurons. Trends in Neurosciences. 29: 257-62. PMID 16564580 DOI: 10.1016/j.tins.2006.03.003  0.147
2012 Nedergaard M, Mikoshiba K, VanHook AM. Science Signaling Podcast: 10 April 2012 Science Signaling. 5: pc8-pc8. DOI: 10.1126/Scisignal.2003064  0.147
2018 Aalling NN, Nedergaard M, DiNuzzo M. Cerebral Metabolic Changes During Sleep. Current Neurology and Neuroscience Reports. 18: 57. PMID 30014344 DOI: 10.1007/s11910-018-0868-9  0.147
2023 Boster KAS, Cai S, Ladrón-de-Guevara A, Sun J, Zheng X, Du T, Thomas JH, Nedergaard M, Karniadakis GE, Kelley DH. Artificial intelligence velocimetry reveals in vivo flow rates, pressure gradients, and shear stresses in murine perivascular flows. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217744120. PMID 36989300 DOI: 10.1073/pnas.2217744120  0.147
1990 Jakobsen J, Nedergaard M, Aarslew-Jensen M, Diemer NH. Regional brain glucose metabolism and blood flow in streptozocin-induced diabetic rats. Diabetes. 39: 437-40. PMID 2318347  0.147
2000 Cotrina ML, Lin JH, López-García JC, Naus CC, Nedergaard M. ATP-mediated glia signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2835-44. PMID 10751435  0.147
1983 Nedergaard M, Klinken L, Paulson OB. Secondary brain stem hemorrhage in stroke. Stroke; a Journal of Cerebral Circulation. 14: 501-5. PMID 6658922 DOI: 10.1161/01.Str.14.4.501  0.146
1995 Nedergaard M. Intracellular Ca2+ transients evoked by lactic acid in cultured mammalian neurons. The American Journal of Physiology. 268: R506-13. PMID 7864248  0.146
2005 Ballabh P, Hu F, Kumarasiri M, Braun A, Nedergaard M. Development of tight junction molecules in blood vessels of germinal matrix, cerebral cortex, and white matter. Pediatric Research. 58: 791-8. PMID 16189211 DOI: 10.1203/01.PDR.0000180535.14093.FB  0.145
2009 Takano T, Oberheim N, Cotrina ML, Nedergaard M. Astrocytes and ischemic injury. Stroke; a Journal of Cerebral Circulation. 40: S8-12. PMID 19064795 DOI: 10.1161/STROKEAHA.108.533166  0.145
2013 Thrane AS, Takano T, Rangroo Thrane V, Wang F, Peng W, Ottersen OP, Nedergaard M, Nagelhus EA. In vivo NADH fluorescence imaging indicates effect of aquaporin-4 deletion on oxygen microdistribution in cortical spreading depression. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 996-9. PMID 23611872 DOI: 10.1038/jcbfm.2013.63  0.145
2019 Ji RR, Donnelly CR, Nedergaard M. Astrocytes in chronic pain and itch. Nature Reviews. Neuroscience. PMID 31537912 DOI: 10.1038/S41583-019-0218-1  0.145
1998 Cotrina ML, Lin JH, Alves-Rodrigues A, Liu S, Li J, Azmi-Ghadimi H, Kang J, Naus CC, Nedergaard M. Connexins regulate calcium signaling by controlling ATP release. Proceedings of the National Academy of Sciences of the United States of America. 95: 15735-40. PMID 9861039 DOI: 10.1073/pnas.95.26.15735  0.144
2023 Ge GR, Song W, Nedergaard M, Rolland JP, Parker KJ. Corrigendum: Theory of sleep/wake cycles affecting brain elastography (2022225013). Physics in Medicine and Biology. 68. PMID 37917188 DOI: 10.1088/1361-6560/ad051f  0.143
2022 Newell DW, Nedergaard M, Aaslid R. Physiological Mechanisms and Significance of Intracranial B Waves. Frontiers in Neurology. 13: 872701. PMID 35651339 DOI: 10.3389/fneur.2022.872701  0.142
2024 Eisen A, Nedergaard M, Gray E, Kiernan MC. THE GLYMPHATIC SYSTEM AND AMYOTROPHIC LATERAL SCLEROSIS. Progress in Neurobiology. 102571. PMID 38266701 DOI: 10.1016/j.pneurobio.2024.102571  0.142
2012 Huang C, Han X, Li X, Lam E, Peng W, Lou N, Torres A, Yang M, Garre JM, Tian GF, Bennett MV, Nedergaard M, Takano T. Critical role of connexin 43 in secondary expansion of traumatic spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3333-8. PMID 22399755 DOI: 10.1523/Jneurosci.1216-11.2012  0.142
2021 Battistella R, Kritsilis M, Matuskova H, Haswell D, Cheng AX, Meissner A, Nedergaard M, Lundgaard I. Not All Lectins Are Equally Suitable for Labeling Rodent Vasculature. International Journal of Molecular Sciences. 22. PMID 34768985 DOI: 10.3390/ijms222111554  0.141
2014 Kristoffersen K, Nedergaard MK, Villingshøj M, Borup R, Broholm H, Kjær A, Poulsen HS, Stockhausen MT. Inhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signature. Cancer Biology & Therapy. 15: 862-77. PMID 24755988 DOI: 10.4161/cbt.28876  0.14
1982 Kromann H, Christy M, Lernmark A, Nedergaard M, Nerup J. The low dose streptozotocin murine model of type 1 (insulin-dependent) diabetes mellitus: studies in vivo and in vitro of the modulating effect of sex hormones. Diabetologia. 22: 194-8. PMID 6210590 DOI: 10.1007/Bf00283752  0.139
2022 Beaman EE, Bonde AN, Ulv Larsen SM, Ozenne B, Lohela TJ, Nedergaard M, Gíslason GH, Knudsen GM, Holst SC. Blood-brain barrier permeable β-blockers linked to lower risk of Alzheimer's disease in hypertension. Brain : a Journal of Neurology. PMID 35196379 DOI: 10.1093/brain/awac076  0.139
2002 Nedergaard M, Takano T, Hansen AJ. Beyond the role of glutamate as a neurotransmitter. Nature Reviews. Neuroscience. 3: 748-55. PMID 12209123 DOI: 10.1038/nrn916  0.138
2012 Christensen DJ, Nedergaard M. Random access multiphoton (RAMP) microscopy for investigation of cerebral blood flow regulation mechanisms. Proceedings of Spie--the International Society For Optical Engineering. 8226. PMID 34267415 DOI: 10.1117/12.907141  0.138
2015 Thrane AS, Rangroo Thrane V, Plog BA, Nedergaard M. Filtering the muddied waters of brain edema. Trends in Neurosciences. 38: 333-5. PMID 26008121 DOI: 10.1016/j.tins.2015.04.009  0.136
2009 Cotrina ML, Nedergaard M. Physiological and pathological functions of P2X7 receptor in the spinal cord. Purinergic Signalling. 5: 223-32. PMID 19205927 DOI: 10.1007/s11302-009-9138-2  0.136
2014 Larsen BR, Assentoft M, Cotrina ML, Hua SZ, Nedergaard M, Kaila K, Voipio J, MacAulay N. Contributions of the Na⁺/K⁺-ATPase, NKCC1, and Kir4.1 to hippocampal K⁺ clearance and volume responses. Glia. 62: 608-22. PMID 24482245 DOI: 10.1002/Glia.22629  0.136
2004 Liu QS, Xu Q, Arcuino G, Kang J, Nedergaard M. Astrocyte-mediated activation of neuronal kainate receptors. Proceedings of the National Academy of Sciences of the United States of America. 101: 3172-7. PMID 14766987 DOI: 10.1073/pnas.0306731101  0.135
2007 Braun A, Xu H, Hu F, Kocherlakota P, Siegel D, Chander P, Ungvari Z, Csiszar A, Nedergaard M, Ballabh P. Paucity of pericytes in germinal matrix vasculature of premature infants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12012-24. PMID 17978043 DOI: 10.1523/JNEUROSCI.3281-07.2007  0.134
1988 Nedergaard M, Diemer NH. Experimental cerebral ischemia: barbiturate resistant increase in regional glucose utilization. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 8: 763-6. PMID 3417802 DOI: 10.1038/jcbfm.1988.125  0.134
2003 Lin JH, Yang J, Liu S, Takano T, Wang X, Gao Q, Willecke K, Nedergaard M. Connexin mediates gap junction-independent resistance to cellular injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 430-41. PMID 12533603 DOI: 10.1523/Jneurosci.23-02-00430.2003  0.134
1987 Nedergaard M, Diemer NH. Focal ischemia of the rat brain, with special reference to the influence of plasma glucose concentration. Acta Neuropathologica. 73: 131-7. PMID 3604580  0.133
2021 Wardlaw JM, Benveniste H, Nedergaard M, Zlokovic BV, Charpak S, Smith KJ, Black SE. Reply to: Rethink the classical view of cerebrospinal fluid production. Nature Reviews. Neurology. PMID 34253900 DOI: 10.1038/s41582-021-00539-z  0.132
2015 Liu X, Wang C, Fujita T, Malmstrom HS, Nedergaard M, Ren YF, Dirksen RT. External Dentin Stimulation Induces ATP Release in Human Teeth. Journal of Dental Research. 94: 1259-66. PMID 26130258 DOI: 10.1177/0022034515592858  0.131
2023 Hirase H, Nedergaard M. Locomotion Induces Fundamentally Different Patterns of Ca Signaling in Astrocytes and Neurons. Function (Oxford, England). 4: zqad028. PMID 37361194 DOI: 10.1093/function/zqad028  0.131
2002 Arcuino G, Lin JH, Takano T, Liu C, Jiang L, Gao Q, Kang J, Nedergaard M. Intercellular calcium signaling mediated by point-source burst release of ATP. Proceedings of the National Academy of Sciences of the United States of America. 99: 9840-5. PMID 12097649 DOI: 10.1073/pnas.152588599  0.131
2014 Lundgaard I, Osório MJ, Kress BT, Sanggaard S, Nedergaard M. White matter astrocytes in health and disease. Neuroscience. 276: 161-73. PMID 24231735 DOI: 10.1016/j.neuroscience.2013.10.050  0.13
2000 Cotrina ML, Nedergaard M. ATP as a messenger in astrocyte-neuronal communication Neuroscientist. 6: 120-126.  0.129
2019 Monai H, Wang X, Yahagi K, Lou N, Mestre H, Xu Q, Abe Y, Yasui M, Iwai Y, Nedergaard M, Hirase H. Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke. Proceedings of the National Academy of Sciences of the United States of America. PMID 31097598 DOI: 10.1073/Pnas.1817347116  0.128
1986 Nedergaard M, Gjedde A, Diemer NH. Focal ischemia of the rat brain: autoradiographic determination of cerebral glucose utilization, glucose content, and blood flow. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 6: 414-24. PMID 3733901 DOI: 10.1038/jcbfm.1986.74  0.128
2004 Liu QS, Xu Q, Kang J, Nedergaard M. Astrocyte activation of presynaptic metabotropic glutamate receptors modulates hippocampal inhibitory synaptic transmission. Neuron Glia Biology. 1: 307-16. PMID 16755304 DOI: 10.1017/S1740925X05000190  0.127
2018 Plog BA, Mestre H, Olveda GE, Sweeney AM, Kenney HM, Cove A, Dholakia KY, Tithof J, Nevins TD, Lundgaard I, Du T, Kelley DH, Nedergaard M. Transcranial optical imaging reveals a pathway for optimizing the delivery of immunotherapeutics to the brain. Jci Insight. 3. PMID 30518698 DOI: 10.1172/jci.insight.126138  0.127
2008 Cotrina ML, Lin JH, Nedergaard M. Adhesive properties of connexin hemichannels. Glia. 56: 1791-8. PMID 18649405 DOI: 10.1002/glia.20728  0.127
2004 Ballabh P, Braun A, Nedergaard M. Anatomic analysis of blood vessels in germinal matrix, cerebral cortex, and white matter in developing infants. Pediatric Research. 56: 117-24. PMID 15128918 DOI: 10.1203/01.PDR.0000130472.30874.FF  0.125
2010 Kang J, Kang N, Yu Y, Zhang J, Petersen N, Tian GF, Nedergaard M. Sulforhodamine 101 induces long-term potentiation of intrinsic excitability and synaptic efficacy in hippocampal CA1 pyramidal neurons. Neuroscience. 169: 1601-9. PMID 20600669 DOI: 10.1016/j.neuroscience.2010.06.020  0.124
2019 Sweeney MD, Montagne A, Sagare AP, Nation DA, Schneider LS, Chui HC, Harrington MG, Pa J, Law M, Wang DJJ, Jacobs RE, Doubal FN, Ramirez J, Black SE, Nedergaard M, et al. Vascular dysfunction-The disregarded partner of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 15: 158-167. PMID 30642436 DOI: 10.1016/J.Jalz.2018.07.222  0.123
1996 Nedergaard M. Spreading depression as a contributor to ischemic brain damage. Advances in Neurology. 71: 75-83; discussion 83. PMID 8790792  0.122
2023 Esmail T, Nedergaard M, Beinlich FRM. Protocol to study molecule exchange between venous blood and CSF in live mice using transcranial bioluminescence imaging. Star Protocols. 4: 102652. PMID 37883226 DOI: 10.1016/j.xpro.2023.102652  0.122
2023 Andersen M, Tsopanidou A, Radovanovic T, Compere VN, Hauglund N, Nedergaard M, Kjaerby C. Using Fiber Photometry in Mice to Estimate Fluorescent Biosensor Levels During Sleep. Bio-Protocol. 13: e4734. PMID 37575397 DOI: 10.21769/BioProtoc.4734  0.12
2024 Hablitz L, Nedergaard M. Synchronized neuronal activity drives waste fluid flow. Nature. PMID 38418726 DOI: 10.1038/d41586-024-00422-z  0.12
2024 Giannetto MJ, Gomolka RS, Gahn-Martinez D, Newbold EJ, Bork PAR, Chang E, Gresser M, Thompson T, Mori Y, Nedergaard M. Glymphatic fluid transport is suppressed by the aquaporin-4 inhibitor AER-271. Glia. PMID 38363040 DOI: 10.1002/glia.24515  0.12
2024 Beschorner N, Nedergaard M. Glymphatic system dysfunction in neurodegenerative diseases. Current Opinion in Neurology. PMID 38345416 DOI: 10.1097/WCO.0000000000001252  0.12
2024 Hussain R, Nedergaard M. Managing noradrenaline after traumatic brain injury. Clinical and Translational Medicine. 14: e1562. PMID 38279839 DOI: 10.1002/ctm2.1562  0.12
2013 Goldman N, Chandler-Militello D, Langevin HM, Nedergaard M, Takano T. Purine receptor mediated actin cytoskeleton remodeling of human fibroblasts. Cell Calcium. 53: 297-301. PMID 23462235 DOI: 10.1016/j.ceca.2013.01.004  0.119
2005 Xu J, Kang N, Jiang L, Nedergaard M, Kang J. Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1750-60. PMID 15716411 DOI: 10.1523/Jneurosci.4217-04.2005  0.118
2020 Ng Kee Kwong KC, Mehta AR, Nedergaard M, Chandran S. Defining novel functions for cerebrospinal fluid in ALS pathophysiology. Acta Neuropathologica Communications. 8: 140. PMID 32819425 DOI: 10.1186/s40478-020-01018-0  0.118
2013 Langevin HM, Fujita T, Bouffard NA, Takano T, Koptiuch C, Badger GJ, Nedergaard M. Fibroblast cytoskeletal remodeling induced by tissue stretch involves ATP signaling. Journal of Cellular Physiology. 228: 1922-6. PMID 23460361 DOI: 10.1002/jcp.24356  0.117
2001 Jiang L, Xu J, Nedergaard M, Kang J. A kainate receptor increases the efficacy of GABAergic synapses. Neuron. 30: 503-13. PMID 11395010 DOI: 10.1016/S0896-6273(01)00298-7  0.116
2014 Verkhratsky A, Nedergaard M. Astroglial cradle in the life of the synapse. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130595. PMID 25225089 DOI: 10.1098/rstb.2013.0595  0.116
2022 Feng W, Zhang Y, Ding S, Chen S, Wang T, Wang Z, Zou Y, Sheng C, Chen Y, Pang Y, Marshall C, Shi J, Nedergaard M, Li Q, Xiao M. B lymphocytes ameliorate Alzheimer's disease-like neuropathology via interleukin-35. Brain, Behavior, and Immunity. 108: 16-31. PMID 36427805 DOI: 10.1016/j.bbi.2022.11.012  0.115
2020 Viggiano D, Wagner CA, Martino G, Nedergaard M, Zoccali C, Unwin R, Capasso G. Mechanisms of cognitive dysfunction in CKD. Nature Reviews. Nephrology. PMID 32235904 DOI: 10.1038/s41581-020-0266-9  0.115
2019 Yoon C, Qi Y, Mestre H, Canavesi C, Marola OJ, Cogliati A, Nedergaard M, Libby RT, Rolland JP. Gabor domain optical coherence microscopy combined with laser scanning confocal fluorescence microscopy. Biomedical Optics Express. 10: 6242-6257. PMID 31853397 DOI: 10.1364/Boe.10.006242  0.115
2009 Rempe DA, Takano T, Nedergaard M. TR(I)Pping towards treatment for ischemia. Nature Neuroscience. 12: 1215-6. PMID 19783978 DOI: 10.1038/Nn1009-1215  0.113
2015 Benveniste H, Hof PR, Nedergaard M, Bechter K. Modern cerebrospinal fluid flow research and Heinrich Quincke's seminal 1872 article on the distribution of cinnabar in freely moving animals. The Journal of Comparative Neurology. 523: 2017-2018. PMID 26190199 DOI: 10.1002/cne.23850  0.113
2007 Takano T, Tian GF, Peng W, Lou N, Lovatt D, Hansen AJ, Kasischke KA, Nedergaard M. Cortical spreading depression causes and coincides with tissue hypoxia. Nature Neuroscience. 10: 754-62. PMID 17468748 DOI: 10.1038/nn1902  0.113
2013 Langevin HM, Nedergaard M, Howe AK. Cellular control of connective tissue matrix tension. Journal of Cellular Biochemistry. 114: 1714-9. PMID 23444198 DOI: 10.1002/jcb.24521  0.11
2012 Kulik T, Nedergaard M, Winn R. Changes in Extracellur Potassium Concentrations within the Physiological Range Affect Extracellular Adenosine Levels and Dynamics in Astrocytic Cultures (P01.029) Neurology. 78: P01.029-P01.029. DOI: 10.1212/WNL.78.1_MEETINGABSTRACTS.P01.029  0.109
2013 Ren Z, Chen X, Yang J, Kress BT, Tong J, Liu H, Takano T, Zhao Y, Nedergaard M. Improved axonal regeneration after spinal cord injury in mice with conditional deletion of ephrin B2 under the GFAP promoter. Neuroscience. 241: 89-99. PMID 23518227 DOI: 10.1016/j.neuroscience.2013.03.010  0.109
1986 Nedergaard M, Astrup J. Infarct rim: effect of hyperglycemia on direct current potential and [14C]2-deoxyglucose phosphorylation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 6: 607-15. PMID 3760045 DOI: 10.1038/jcbfm.1986.108  0.109
2007 Jaiswal JK, Fix M, Takano T, Nedergaard M, Simon SM. Resolving vesicle fusion from lysis to monitor calcium-triggered lysosomal exocytosis in astrocytes. Proceedings of the National Academy of Sciences of the United States of America. 104: 14151-6. PMID 17715060 DOI: 10.1073/pnas.0704935104  0.108
2012 Christensen DJ, Nedergaard M. Random access multiphoton (RAMP) microscopy for investigation of cerebral blood flow regulation mechanisms Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8226. DOI: 10.1117/12.907141  0.107
2020 Yuste R, Hawrylycz M, Aalling N, Aguilar-Valles A, Arendt D, Arnedillo RA, Ascoli GA, Bielza C, Bokharaie V, Bergmann TB, Bystron I, Capogna M, Chang Y, Clemens A, de Kock CPJ, ... ... Nedergaard M, et al. A community-based transcriptomics classification and nomenclature of neocortical cell types. Nature Neuroscience. PMID 32839617 DOI: 10.1038/S41593-020-0685-8  0.107
2016 Cotrina ML, Lou N, Tome-Garcia J, Goldman J, Nedergaard M. Direct comparison of microglial dynamics and inflammatory profile in photothrombotic and arterial occlusion evoked stroke. Neuroscience. PMID 28003156 DOI: 10.1016/j.neuroscience.2016.12.012  0.107
2019 Zvietcovich F, Ge GR, Mestre H, Giannetto M, Nedergaard M, Rolland JP, Parker KJ. Longitudinal shear waves for elastic characterization of tissues in optical coherence elastography. Biomedical Optics Express. 10: 3699-3718. PMID 31360610 DOI: 10.1364/Boe.10.003699  0.107
2011 Kasischke KA, Lambert EM, Panepento B, Sun A, Gelbard HA, Burgess RW, Foster TH, Nedergaard M. Two-photon NADH imaging exposes boundaries of oxygen diffusion in cortical vascular supply regions. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 68-81. PMID 20859293 DOI: 10.1038/Jcbfm.2010.158  0.107
1988 Nedergaard M, Jakobsen J, Diemer NH. Autoradiographic determination of cerebral glucose content, blood flow, and glucose utilization in focal ischemia of the rat brain: influence of the plasma glucose concentration. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 8: 100-8. PMID 3339100 DOI: 10.1038/jcbfm.1988.13  0.107
2012 Christensen DJ, Nedergaard M. Random access multiphoton (RAMP) microscopy for investigation of capillary-level cerebral blood flow mechanisms Frontiers in Optics, Fio 2012 0.104
2016 Jiang Q, Zhang L, Ding G, Davoodi-Bojd E, Li Q, Li L, Sadry N, Nedergaard M, Chopp M, Zhang Z. Impairment of the glymphatic system after diabetes. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27306755 DOI: 10.1177/0271678X16654702  0.102
2004 Kang N, Jiang L, He W, Xu J, Nedergaard M, Kang J. Presynaptic inactivation of action potentials and postsynaptic inhibition of GABAA currents contribute to KA-induced disinhibition in CA1 pyramidal neurons. Journal of Neurophysiology. 92: 873-82. PMID 14999044 DOI: 10.1152/Jn.01231.2003  0.101
2021 Martikainen MV, Aakko-Saksa P, van den Broek L, Cassee FR, Carare RO, Chew S, Dinnyes A, Giugno R, Kanninen KM, Malm T, Muala A, Nedergaard M, Oudin A, Oyola P, Pfeiffer TV, et al. TUBE Project: Transport-Derived Ultrafines and the Brain Effects. International Journal of Environmental Research and Public Health. 19. PMID 35010571 DOI: 10.3390/ijerph19010311  0.1
2010 Goldman N, Chen M, Fujita T, Xu Q, Peng W, Liu W, Jensen TK, Pei Y, Wang F, Han X, Chen JF, Schnermann J, Takano T, Bekar L, Tieu K, ... Nedergaard M, et al. Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture. Nature Neuroscience. 13: 883-8. PMID 20512135 DOI: 10.1038/Nn.2562  0.1
2020 Koundal S, Elkin R, Nadeem S, Xue Y, Constantinou S, Sanggaard S, Liu X, Monte B, Xu F, Nostrand WV, Nedergaard M, Lee H, Wardlaw J, Benveniste H, Tannenbaum A. Publisher Correction: Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System. Scientific Reports. 10: 3934. PMID 32107453 DOI: 10.1038/S41598-020-60586-2  0.1
1998 Cotrina ML, Lin JH, Nedergaard M. Cytoskeletal assembly and ATP release regulate astrocytic calcium signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 8794-804. PMID 9786986  0.1
2014 Plog BA, Moll KM, Kang H, Iliff JJ, Dashnaw ML, Nedergaard M, Vates GE. A novel technique for morphometric quantification of subarachnoid hemorrhage-induced microglia activation. Journal of Neuroscience Methods. 229: 44-52. PMID 24735531 DOI: 10.1016/j.jneumeth.2014.04.001  0.099
1993 Nedergaard M, Hansen AJ. Characterization of cortical depolarizations evoked in focal cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 13: 568-74. PMID 8314912 DOI: 10.1038/jcbfm.1993.74  0.099
1997 Wang Z, Tymianski M, Jones OT, Nedergaard M. Impact of cytoplasmic calcium buffering on the spatial and temporal characteristics of intercellular calcium signals in astrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7359-71. PMID 9295382 DOI: 10.1523/Jneurosci.17-19-07359.1997  0.098
1983 Nedergaard M, Egeberg J, Kromann H. Irradiation protects against pancreatic islet degeneration and hyperglycaemia following streptozotocin treatment of mice. Diabetologia. 24: 382-6. PMID 6347786  0.097
1991 Nedergaard M, Kraig RP, Tanabe J, Pulsinelli WA. Dynamics of interstitial and intracellular pH in evolving brain infarct. The American Journal of Physiology. 260: R581-8. PMID 2001008 DOI: 10.1152/Ajpregu.1991.260.3.R581  0.094
2014 Nedergaard MK, Kristoffersen K, Michaelsen SR, Madsen J, Poulsen HS, Stockhausen MT, Lassen U, Kjaer A. The use of longitudinal 18F-FET MicroPET imaging to evaluate response to irinotecan in orthotopic human glioblastoma multiforme xenografts. Plos One. 9: e100009. PMID 24918622 DOI: 10.1371/journal.pone.0100009  0.093
2023 Hussain R, Graham U, Elder A, Nedergaard M. Air pollution, glymphatic impairment, and Alzheimer's disease. Trends in Neurosciences. 46: 901-911. PMID 37777345 DOI: 10.1016/j.tins.2023.08.010  0.092
2023 Untiet V, Nedergaard M, Verkhratsky A. Astrocyte chloride, excitatory-inhibitory balance and epilepsy. Neural Regeneration Research. 19: 1887. PMID 38227511 DOI: 10.4103/1673-5374.390981  0.092
2022 Wu SY, Wen Y, Serre NBC, Laursen CCH, Dietz AG, Taylor BR, Drobizhev M, Molina RS, Aggarwal A, Rancic V, Becker M, Ballanyi K, Podgorski K, Hirase H, Nedergaard M, et al. A sensitive and specific genetically-encoded potassium ion biosensor for in vivo applications across the tree of life. Plos Biology. 20: e3001772. PMID 36067248 DOI: 10.1371/journal.pbio.3001772  0.092
1997 Rawanduzy A, Hansen A, Hansen TW, Nedergaard M. Effective reduction of infarct volume by gap junction blockade in a rodent model of stroke. Journal of Neurosurgery. 87: 916-20. PMID 9384404 DOI: 10.3171/jns.1997.87.6.0916  0.091
2022 Kjaerby C, Andersen M, Hauglund N, Untiet V, Dall C, Sigurdsson B, Ding F, Feng J, Li Y, Weikop P, Hirase H, Nedergaard M. Memory-enhancing properties of sleep depend on the oscillatory amplitude of norepinephrine. Nature Neuroscience. 25: 1059-1070. PMID 35798980 DOI: 10.1038/s41593-022-01102-9  0.091
2018 Lundgaard I, Wang W, Eberhardt A, Vinitsky HS, Reeves BC, Peng S, Lou N, Hussain R, Nedergaard M. Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function. Scientific Reports. 8: 2246. PMID 29396480 DOI: 10.1038/s41598-018-20424-y  0.09
1997 Rawanduzy A, Hansen A, Hansen TW, Nedergaard M. Effective reduction of infarct volume by gap junction blockade in a rodent model of stroke. Neurosurgical Focus. 2: E1; discussion 1 p f. PMID 15096002  0.09
2022 Monai H, Koketsu S, Shinohara Y, Ueki T, Kusk P, Hauglund NL, Samson AJ, Nedergaard M, Hirase H. Author Correction: Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization. Scientific Reports. 12: 4741. PMID 35304562 DOI: 10.1038/s41598-022-08615-0  0.089
2000 Jiang L, Sun S, Nedergaard M, Kang J. Paired-pulse modulation at individual GABAergic synapses in rat hippocampus. The Journal of Physiology. 523: 425-39. PMID 10699086  0.088
2000 Zhang W, Couldwell WT, Song H, Takano T, Lin JH, Nedergaard M. Tamoxifen-induced enhancement of calcium signaling in glioma and MCF-7 breast cancer cells. Cancer Research. 60: 5395-400. PMID 11034078  0.085
2013 Iliff JJ, Nedergaard M. Is there a cerebral lymphatic system? Stroke; a Journal of Cerebral Circulation. 44: S93-5. PMID 23709744 DOI: 10.1161/STROKEAHA.112.678698  0.084
2013 Iliff JJ, Nedergaard M. A link between glial Ca2+ signaling and hypoxia in aging? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 170. PMID 23211967 DOI: 10.1038/jcbfm.2012.182  0.083
2008 Xu H, Hu F, Sado Y, Ninomiya Y, Borza DB, Ungvari Z, Lagamma EF, Csiszar A, Nedergaard M, Ballabh P. Maturational changes in laminin, fibronectin, collagen IV, and perlecan in germinal matrix, cortex, and white matter and effect of betamethasone. Journal of Neuroscience Research. 86: 1482-500. PMID 18214989 DOI: 10.1002/jnr.21618  0.082
1987 Nedergaard M. Neuronal injury in the infarct border: a neuropathological study in the rat. Acta Neuropathologica. 73: 267-74. PMID 3618118  0.081
2009 Hedley-Whyte ET, Goldman JE, Nedergaard M, Friedman A, Han X, Schmidt RE, Powers JM. Hyaline protoplasmic astrocytopathy of neocortex. Journal of Neuropathology and Experimental Neurology. 68: 136-47. PMID 19151628 DOI: 10.1097/Nen.0B013E318195203  0.08
2023 Parka A, Volbracht C, Hall B, Bastlund JF, Nedergaard M, Laursen B, Botta P, Sotty F. Visual Evoked Potentials as an Early-Stage Biomarker in the rTg4510 Tauopathy Mouse Model. Journal of Alzheimer's Disease : Jad. PMID 37005884 DOI: 10.3233/JAD-220964  0.078
2018 Horsburgh K, Wardlaw JM, van Agtmael T, Allan SM, Ashford MLJ, Bath PM, Brown R, Berwick J, Cader MZ, Carare RO, Davis JB, Duncombe J, Farr TD, Fowler JH, Goense J, ... ... Nedergaard M, et al. Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. Clinical Science (London, England : 1979). 132: 851-868. PMID 29712883 DOI: 10.1042/Cs20171620  0.077
2007 Takano T, Nedergaard M. DM-nitrophen provides physiologically significant increases of intracellular [Ca2+] in the presence of Mg2+. Cell Calcium. 41: 503-4. PMID 17055047 DOI: 10.1016/j.ceca.2006.09.004  0.076
2015 Persson M, Nedergaard M, Brandt-Larsen M, Skovgaard D, Jørgensen JT, Michaelsen SR, Madsen J, Lassen U, Poulsen HS, Kjaer A. uPAR is a Promising New Imaging Biomarker in Glioblastoma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26429955 DOI: 10.2967/jnumed.115.161703  0.076
2023 Kjaerby C, Andersen M, Hauglund N, Untiet V, Dall C, Ding F, Hirase H, Nedergaard M. Reply to: 'Do all norepinephrine surges disrupt sleep?'. Nature Neuroscience. PMID 37081298 DOI: 10.1038/s41593-023-01314-7  0.076
2023 Nasu Y, Aggarwal A, Le GNT, Vo CT, Kambe Y, Wang X, Beinlich FRM, Lee AB, Ram TR, Wang F, Gorzo KA, Kamijo Y, Boisvert M, Nishinami S, Kawamura G, ... ... Nedergaard M, et al. Lactate biosensors for spectrally and spatially multiplexed fluorescence imaging. Nature Communications. 14: 6598. PMID 37891202 DOI: 10.1038/s41467-023-42230-5  0.075
2023 Staudt M, Shalgunov V, Nedergaard M, Herth MM. Development of C-labeled CRANAD-102 for positron emission tomography imaging of soluble Aβ-species. Journal of Labelled Compounds & Radiopharmaceuticals. 66: 393-399. PMID 37653688 DOI: 10.1002/jlcr.4060  0.069
1987 Nedergaard M. Transient focal ischemia in hyperglycemic rats is associated with increased cerebral infarction. Brain Research. 408: 79-85. PMID 3594232  0.068
2013 Rangroo Thrane V, Thrane AS, Chang J, Alleluia V, Nagelhus EA, Nedergaard M. Corrigendum to "Real-time analysis of microglial activation and motility in hepatic and hyperammonemic encephalopathy" [Neuroscience 220 (2012) 247-255] Neuroscience. 233: 184. DOI: 10.1016/j.neuroscience.2012.12.037  0.068
1988 Sillesen H, Nedergaard M, Schroeder T, Buchardt Hansen HJ. Middle cerebral artery occlusion in presence of low perfusion pressure increases infarct size in rats. Neurological Research. 10: 61-3. PMID 2899857  0.065
2011 Christensen DJ, Nedergaard M. Two-photon in vivo imaging of cells. Pediatric Nephrology (Berlin, Germany). 26: 1483-9. PMID 21404099 DOI: 10.1007/s00467-011-1818-9  0.063
2012 Verkhratsky A, Nedergaard M. Supporting the cell, supporting the science: An editorial essay Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 1: 1-2. DOI: 10.1002/wmts.31  0.061
1990 Nedergaard M, Desai S, Pulsinelli W. Dicarboxy-dichlorofluorescein: a new fluorescent probe for measuring acidic intracellular pH. Analytical Biochemistry. 187: 109-14. PMID 2372106  0.061
2015 Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, et al. Vascular contributions to cognitive impairment and dementia including Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 710-717. PMID 25510382 DOI: 10.1016/J.Jalz.2014.10.008  0.06
2020 Yuste R, Hawrylycz M, Aalling N, Aguilar-Valles A, Arendt D, Arnedillo RA, Ascoli GA, Bielza C, Bokharaie V, Bergmann TB, Bystron I, Capogna M, Chang Y, Clemens A, de Kock CPJ, ... ... Nedergaard M, et al. Publisher Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types. Nature Neuroscience. PMID 33277642 DOI: 10.1038/s41593-020-00768-3  0.06
2019 Verkhratsky A, Nedergaard M, Steardo L, Li B. Editorial: Sleep and Mood Disorders. Frontiers in Psychiatry. 10: 981. PMID 32010001 DOI: 10.3389/fpsyt.2019.00981  0.059
2021 Yuste R, Hawrylycz M, Aalling N, Aguilar-Valles A, Arendt D, Armañanzas R, Ascoli GA, Bielza C, Bokharaie V, Bergmann TB, Bystron I, Capogna M, Chang Y, Clemens A, de Kock CPJ, ... ... Nedergaard M, et al. Author Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types. Nature Neuroscience. PMID 33742182 DOI: 10.1038/s41593-020-00779-0  0.055
2013 Cotrina ML, Nedergaard M. Intracellular Calcium Control Mechanisms in Glia Neuroglia. DOI: 10.1093/acprof:oso/9780195152227.003.0017  0.054
2010 Nedergaard M, Verkhratsky A. Calcium dyshomeostasis and pathological calcium signalling in neurological diseases. Cell Calcium. 47: 101-2. PMID 20079921 DOI: 10.1016/j.ceca.2009.12.011  0.051
2010 Rempe DA, Nedergaard M. Targeting glia for treatment of neurological disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 7: 335-7. PMID 20880498 DOI: 10.1016/J.Nurt.2010.08.003  0.048
2016 Xie L, Kang H, Nedergaard M. A Novel Model of Transient Occlusion of the Middle Cerebral Artery in Awake Mice. Journal of Nature and Science. 2. PMID 27774515  0.047
2023 Raizen DM, Mullington J, Anaclet C, Clarke G, Critchley H, Dantzer R, Davis R, Drew KL, Fessel J, Fuller PM, Gibson EM, Harrington M, Lipkin WI, Klerman EB, Klimas N, ... ... Nedergaard M, et al. Beyond the Symptom: The Biology of Fatigue. Sleep. PMID 37224457 DOI: 10.1093/sleep/zsad069  0.044
2015 Nedergaard MK, Michaelsen SR, Urup T, Broholm H, El Ali H, Poulsen HS, Stockhausen MT, Kjaer A, Lassen U. 18F-FET microPET and microMRI for anti-VEGF and anti-PlGF response assessment in an orthotopic murine model of human glioblastoma. Plos One. 10: e0115315. PMID 25680186 DOI: 10.1371/journal.pone.0115315  0.038
2012 Nedergaard MK, Hedegaard CJ, Poulsen HS. Targeting the epidermal growth factor receptor in solid tumor malignancies. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. 26: 83-99. PMID 22385404 DOI: 10.2165/11599760-000000000-00000  0.034
1972 Nedergaard M, Norn MS, Sjontoft F. [Single-dose eye drops]. Ugeskrift For Laeger. 134: 2271-3. PMID 4634649  0.033
2010 Cotrina ML, Nedergaard M. Calcium Waves: Purinergic Regulation Encyclopedia of Neuroscience. 575-579. DOI: 10.1016/B978-008045046-9.01724-1  0.029
2007 Takano T, Tian G, Hansen AJ, Nedergaard M. The two-photon microscopic analysis of cortical spreading depression Neuroscience Research. 58: S29. DOI: 10.1016/j.neures.2007.06.168  0.028
1975 Nedergaard M. Pharmacy in Scandinavia: a corner of the Old World. Hospital Formulary. 10: 348, 351, 354-5. PMID 10237846  0.025
2012 Messing A, Brenner M, Feany MB, Nedergaard M, Goldman JE. Alexander disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5017-23. PMID 22496548 DOI: 10.1523/JNEUROSCI.5384-11.2012  0.023
1967 Nedergaard M. [Investigations on colour reaction between guinol-sulphuric acid and diethylstibestrol and related compounds]. Dansk Tidsskrift For Farmaci. 41: 125-36. PMID 5594484  0.019
1968 Nedergaard M. Colorimetric determination of dienoestrol: quinol-sulphuric acid IV. Bollettino Chimico Farmaceutico. 107: 570-3. PMID 5737048  0.019
1967 Nedergaard M. [Hydroquinone-sulfuric acid reagents. 3. Colorimetric determination of diethylstilbestrol]. Journal De Pharmacie De Belgique. 22: 323-8. PMID 5608932  0.017
1977 Nedergaard M. [Not Available]. Revue D'Histoire De La Pharmacie. 24: 167-72. PMID 11627441  0.013
1966 Amdrup E, Bonfils K, Christensen P, Nedergaard M. [The use of karaya-gum powder and aluminum hydroxide gel in cases of external gastrointestinal fistula or stoma]. Nordisk Medicin. 75: 598-9. PMID 5934733  0.012
2010 Vates GE, Takano T, Zlokovic B, Nedergaard M. Pericyte constriction after stroke: the jury is still out. Nature Medicine. 16: 959; author reply 96. PMID 20823870 DOI: 10.1038/Nm0910-959  0.011
2013 Nedergaard M, Verkhratsky A. The birth of the journal: The first anniversary of WIREs MTS Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 2: 105-105. DOI: 10.1002/wmts.81  0.01
2007 Dermietzel R, Spray DC, Nedergaard M. Preface Blood-Brain Barriers: From Ontogeny to Artificial Interfaces. 1: xxiii. DOI: 10.1002/9783527611225  0.01
1987 Nedergaard M, Gjedde A, Diemer NH. To the Editor Journal of Cerebral Blood Flow & Metabolism. 7: 132-134. DOI: 10.1038/jcbfm.1987.21  0.01
1977 Nedergaard M. Health care and hospital pharmacy in Denmark. American Journal of Hospital Pharmacy. 34: 595-600. PMID 879180  0.01
1972 Mackeprang B, Nedergaard M. [Discussion of a "home-pharmacy"]. Ugeskrift For Laeger. 134: 2038-43. PMID 5077736  0.01
1970 Nedergaard M. Analytical study of L-dopa (substance and tablets). Pharmaceutica Acta Helvetiae. 45: 373-8. PMID 5426101  0.01
1969 Nedergaard M, Collado Mdel C. [On the stability of phenoxybenzamine in parental solution. 2]. Pharmaceutica Acta Helvetiae. 44: 541-6. PMID 5821944  0.01
1968 Collado Mdel C, Nedergaard M. [On the stability of phenoxybenzamine hydrochloride in solution]. Annales Pharmaceutiques Franã§Aises. 26: 409-12. PMID 5708743  0.01
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