David C. S. Roberts - Publications

Affiliations: 
Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
Neurobiology of Drug Addiction
Website:
http://www1.wfubmc.edu/PhysPharm/faculty/dcsr/

151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Roberts DCS, Zimmer BA. Hold-down as an alternative to unit dose in cocaine self-administration experiments: Characterization using a progressive ratio schedule. Psychopharmacology. PMID 32468100 DOI: 10.1007/s00213-020-05565-1  1
2017 Allain F, Roberts DC, Lévesque D, Samaha AN. Intermittent intake of rapid cocaine injections promotes robust psychomotor sensitization, increased incentive motivation for the drug and mGlu2/3 receptor dysregulation. Neuropharmacology. PMID 28137451 DOI: 10.1016/j.neuropharm.2017.01.026  1
2015 Allain F, Minogianis EA, Roberts DC, Samaha AN. How fast and how often: The pharmacokinetics of drug use are decisive in addiction. Neuroscience and Biobehavioral Reviews. PMID 26116543 DOI: 10.1016/j.neubiorev.2015.06.012  1
2014 Young KA, Franklin TR, Roberts DC, Jagannathan K, Suh JJ, Wetherill RR, Wang Z, Kampman KM, O'Brien CP, Childress AR. Nipping cue reactivity in the bud: baclofen prevents limbic activation elicited by subliminal drug cues. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 5038-43. PMID 24695721 DOI: 10.1523/JNEUROSCI.4977-13.2014  1
2014 Zimmer BA, Chiodo KA, Roberts DC. Reduction of the reinforcing effectiveness of cocaine by continuous D-amphetamine treatment in rats: importance of active self-administration during treatment period. Psychopharmacology. 231: 949-54. PMID 24146137 DOI: 10.1007/s00213-013-3305-4  1
2014 Calipari ES, Ferris MJ, Melchior JR, Bermejo K, Salahpour A, Roberts DC, Jones SR. Methylphenidate and cocaine self-administration produce distinct dopamine terminal alterations. Addiction Biology. 19: 145-55. PMID 22458761 DOI: 10.1111/j.1369-1600.2012.00456.x  1
2013 Crawford JT, Roberts DC, Beveridge TJ. The group II metabotropic glutamate receptor agonist, LY379268, decreases methamphetamine self-administration in rats. Drug and Alcohol Dependence. 132: 414-9. PMID 23953655 DOI: 10.1016/j.drugalcdep.2013.07.024  0.04
2013 Ferris MJ, Calipari ES, Melchior JR, Roberts DC, España RA, Jones SR. Paradoxical tolerance to cocaine after initial supersensitivity in drug-use-prone animals. The European Journal of Neuroscience. 38: 2628-36. PMID 23725404 DOI: 10.1111/ejn.12266  1
2013 Calipari ES, Ferris MJ, Zimmer BA, Roberts DC, Jones SR. Temporal pattern of cocaine intake determines tolerance vs sensitization of cocaine effects at the dopamine transporter. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2385-92. PMID 23719505 DOI: 10.1038/npp.2013.136  1
2013 Roberts DC, Gabriele A, Zimmer BA. Conflation of cocaine seeking and cocaine taking responses in IV self-administration experiments in rats: methodological and interpretational considerations. Neuroscience and Biobehavioral Reviews. 37: 2026-36. PMID 23669047 DOI: 10.1016/j.neubiorev.2013.04.017  1
2013 Blume LC, Bass CE, Childers SR, Dalton GD, Roberts DC, Richardson JM, Xiao R, Selley DE, Howlett AC. Striatal CB1 and D2 receptors regulate expression of each other, CRIP1A and δ opioid systems. Journal of Neurochemistry. 124: 808-20. PMID 23286559 DOI: 10.1111/jnc.12139  1
2013 Zimmer BA, Dobrin CV, Roberts DC. Examination of behavioral strategies regulating cocaine intake in rats. Psychopharmacology. 225: 935-44. PMID 22993052 DOI: 10.1007/s00213-012-2877-8  1
2012 Zimmer BA, Oleson EB, Roberts DC. The motivation to self-administer is increased after a history of spiking brain levels of cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1901-10. PMID 22453139 DOI: 10.1038/npp.2012.37  1
2012 Ferris MJ, Calipari ES, Mateo Y, Melchior JR, Roberts DC, Jones SR. Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1708-16. PMID 22395730 DOI: 10.1038/npp.2012.17  1
2012 Oleson EB, Roberts DC. Cocaine self-administration in rats: threshold procedures. Methods in Molecular Biology (Clifton, N.J.). 829: 303-19. PMID 22231823 DOI: 10.1007/978-1-61779-458-2_20  1
2012 Dobrin CV, Roberts DC. Cocaine self-administration in rats: discrete trials procedures. Methods in Molecular Biology (Clifton, N.J.). 829: 291-302. PMID 22231822 DOI: 10.1007/978-1-61779-458-2_19  1
2012 Zimmer BA, Roberts DC. Cocaine self-administration in rats: hold-down procedures. Methods in Molecular Biology (Clifton, N.J.). 829: 279-90. PMID 22231821 DOI: 10.1007/978-1-61779-458-2_18  1
2012 Czoty PW, Roberts DC. Thinking outside the synapse: pharmacokinetic-based medications for cocaine addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1079-80. PMID 22071873 DOI: 10.1038/npp.2011.269  1
2011 Zimmer BA, Dobrin CV, Roberts DC. Brain-cocaine concentrations determine the dose self-administered by rats on a novel behaviorally dependent dosing schedule. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2741-9. PMID 21849981 DOI: 10.1038/npp.2011.165  1
2011 Oleson EB, Richardson JM, Roberts DC. A novel IV cocaine self-administration procedure in rats: differential effects of dopamine, serotonin, and GABA drug pre-treatments on cocaine consumption and maximal price paid. Psychopharmacology. 214: 567-77. PMID 21110008 DOI: 10.1007/s00213-010-2058-6  1
2011 España RA, Melchior JR, Roberts DC, Jones SR. Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration. Psychopharmacology. 214: 415-26. PMID 20959967 DOI: 10.1007/s00213-010-2048-8  1
2011 Ferris MJ, Mateo Y, Roberts DC, Jones SR. Cocaine-insensitive dopamine transporters with intact substrate transport produced by self-administration. Biological Psychiatry. 69: 201-7. PMID 20801429 DOI: 10.1016/j.biopsych.2010.06.026  1
2010 Bass CE, Jansen HT, Roberts DC. Free-running rhythms of cocaine self-administration in rats held under constant lighting conditions. Chronobiology International. 27: 535-48. PMID 20524799 DOI: 10.3109/07420521003664221  1
2010 Freeman WM, Lull ME, Patel KM, Brucklacher RM, Morgan D, Roberts DC, Vrana KE. Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration. Bmc Neuroscience. 11: 29. PMID 20187946 DOI: 10.1186/1471-2202-11-29  1
2010 España RA, Oleson EB, Locke JL, Brookshire BR, Roberts DC, Jones SR. The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system. The European Journal of Neuroscience. 31: 336-48. PMID 20039943 DOI: 10.1111/j.1460-9568.2009.07065.x  1
2009 Lull ME, Erwin MS, Morgan D, Roberts DC, Vrana KE, Freeman WM. Persistent proteomic alterations in the medial prefrontal cortex with abstinence from cocaine self-administration. Proteomics. Clinical Applications. 3: 462-472. PMID 20161123 DOI: 10.1002/prca.200800055  1
2009 Chiodo KA, Roberts DC. Decreased reinforcing effects of cocaine following 2 weeks of continuous D-amphetamine treatment in rats. Psychopharmacology. 206: 447-56. PMID 19652955 DOI: 10.1007/s00213-009-1622-4  1
2009 Oleson EB, Roberts DC. Behavioral economic assessment of price and cocaine consumption following self-administration histories that produce escalation of either final ratios or intake. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 796-804. PMID 18971927 DOI: 10.1038/npp.2008.195  1
2009 Oleson EB, Talluri S, Childers SR, Smith JE, Roberts DC, Bonin KD, Budygin EA. Dopamine uptake changes associated with cocaine self-administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1174-84. PMID 18923398 DOI: 10.1038/npp.2008.186  1
2009 Morgan D, Liu Y, Oleson EB, Roberts DC. Cocaine self-administration on a hold-down schedule of reinforcement in rats. Psychopharmacology. 201: 601-9. PMID 18797847 DOI: 10.1007/s00213-008-1328-z  1
2008 Oleson EB, Roberts DC. Parsing the Addiction Phenomenon: Self-Administration Procedures Modeling Enhanced Motivation for Drug and Escalation of Drug Intake. Drug Discovery Today. Disease Models. 5: 217-226. PMID 20216935 DOI: 10.1016/j.ddmod.2009.04.001  1
2008 Chiodo KA, Läck CM, Roberts DC. Cocaine self-administration reinforced on a progressive ratio schedule decreases with continuous D-amphetamine treatment in rats. Psychopharmacology. 200: 465-73. PMID 18604521 DOI: 10.1007/s00213-008-1222-8  1
2008 España RA, Roberts DC, Jones SR. Short-acting cocaine and long-acting GBR-12909 both elicit rapid dopamine uptake inhibition following intravenous delivery. Neuroscience. 155: 250-7. PMID 18597947 DOI: 10.1016/j.neuroscience.2008.05.022  1
2008 Fuxe K, Marcellino D, Rivera A, Diaz-Cabiale Z, Filip M, Gago B, Roberts DC, Langel U, Genedani S, Ferraro L, de la Calle A, Narvaez J, Tanganelli S, Woods A, Agnati LF. Receptor-receptor interactions within receptor mosaics. Impact on neuropsychopharmacology. Brain Research Reviews. 58: 415-52. PMID 18222544 DOI: 10.1016/j.brainresrev.2007.11.007  1
2008 Smith MA, Ward SJ, Roberts DC. Lesions of the dorsomedial frontal cortex block sensitization to the positive-reinforcing effects of cocaine. Pharmacology, Biochemistry, and Behavior. 88: 238-46. PMID 17904623 DOI: 10.1016/j.pbb.2007.08.007  1
2008 Lack CM, Jones SR, Roberts DC. Increased breakpoints on a progressive ratio schedule reinforced by IV cocaine are associated with reduced locomotor activation and reduced dopamine efflux in nucleus accumbens shell in rats. Psychopharmacology. 195: 517-25. PMID 17879088 DOI: 10.1007/s00213-007-0919-4  1
2008 Freeman WM, Patel KM, Brucklacher RM, Lull ME, Erwin M, Morgan D, Roberts DC, Vrana KE. Persistent alterations in mesolimbic gene expression with abstinence from cocaine self-administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1807-17. PMID 17851536 DOI: 10.1038/sj.npp.1301577  1
2007 Burkhardt JM, Constantinidis C, Anstrom KK, Roberts DC, Woodward DJ. Synchronous oscillations and phase reorganization in the basal ganglia during akinesia induced by high-dose haloperidol. The European Journal of Neuroscience. 26: 1912-24. PMID 17897397 DOI: 10.1111/j.1460-9568.2007.05813.x  1
2007 Roberts DC, Morgan D, Liu Y. How to make a rat addicted to cocaine. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 31: 1614-24. PMID 17888555 DOI: 10.1016/j.pnpbp.2007.08.028  1
2007 Liu Y, Morgan D, Roberts DC. Cross-sensitization of the reinforcing effects of cocaine and amphetamine in rats. Psychopharmacology. 195: 369-75. PMID 17710385 DOI: 10.1007/s00213-007-0909-6  1
2007 Ward SJ, Roberts DC. Microinjection of the delta-opioid receptor selective antagonist naltrindole 5'-isothiocyanate site specifically affects cocaine self-administration in rats responding under a progressive ratio schedule of reinforcement. Behavioural Brain Research. 182: 140-4. PMID 17572514 DOI: 10.1016/j.bbr.2007.05.003  1
2007 Anstrom KK, Schallert T, Woodlee MT, Shattuck A, Roberts DC. Repetitive vibrissae-elicited forelimb placing before and immediately after unilateral 6-hydroxydopamine improves outcome in a model of Parkinson's disease. Behavioural Brain Research. 179: 183-91. PMID 17374405 DOI: 10.1016/j.bbr.2007.01.028  1
2007 Marcellino D, Roberts DC, Navarro G, Filip M, Agnati L, Lluís C, Franco R, Fuxe K. Increase in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal. Brain Research. 1143: 208-20. PMID 17320828 DOI: 10.1016/j.brainres.2007.01.079  1
2006 McCracken CB, Roberts DC. A single evoked afterdischarge produces rapid time-dependent changes in connexin36 protein expression in adult rat dorsal hippocampus. Neuroscience Letters. 405: 84-8. PMID 16859830 DOI: 10.1016/j.neulet.2006.06.025  1
2006 Wojnicki FH, Roberts DC, Corwin RL. Effects of baclofen on operant performance for food pellets and vegetable shortening after a history of binge-type behavior in non-food deprived rats. Pharmacology, Biochemistry, and Behavior. 84: 197-206. PMID 16782181 DOI: 10.1016/j.pbb.2006.04.015  0.01
2006 McCracken CB, Roberts DC. Neuronal gap junctions: expression, function, and implications for behavior. International Review of Neurobiology. 73: 125-51. PMID 16737903 DOI: 10.1016/S0074-7742(06)73004-5  1
2006 Filip M, Frankowska M, Zaniewska M, PrzegaliÅ„ski E, Muller CE, Agnati L, Franco R, Roberts DC, Fuxe K. Involvement of adenosine A2A and dopamine receptors in the locomotor and sensitizing effects of cocaine. Brain Research. 1077: 67-80. PMID 16516871 DOI: 10.1016/j.brainres.2006.01.038  1
2006 Ward SJ, Läck C, Morgan D, Roberts DC. Discrete-trials heroin self-administration produces sensitization to the reinforcing effects of cocaine in rats. Psychopharmacology. 185: 150-9. PMID 16416157 DOI: 10.1007/s00213-005-0288-9  1
2006 Morgan D, Liu Y, Roberts DC. Rapid and persistent sensitization to the reinforcing effects of cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 121-8. PMID 15920502 DOI: 10.1038/sj.npp.1300773  1
2005 McCracken CB, Hamby SM, Patel KM, Morgan D, Vrana KE, Roberts DC. Extended cocaine self-administration and deprivation produces region-specific and time-dependent changes in connexin36 expression in rat brain. Synapse (New York, N.Y.). 58: 141-50. PMID 16138316 DOI: 10.1002/syn.20194  1
2005 Roberts DC. Preclinical evidence for GABAB agonists as a pharmacotherapy for cocaine addiction. Physiology & Behavior. 86: 18-20. PMID 16061264 DOI: 10.1016/j.physbeh.2005.06.017  0.01
2005 Liu Y, Roberts DC, Morgan D. Sensitization of the reinforcing effects of self-administered cocaine in rats: effects of dose and intravenous injection speed. The European Journal of Neuroscience. 22: 195-200. PMID 16029209 DOI: 10.1111/j.1460-9568.2005.04195.x  1
2005 Mateo Y, Lack CM, Morgan D, Roberts DC, Jones SR. Reduced dopamine terminal function and insensitivity to cocaine following cocaine binge self-administration and deprivation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1455-63. PMID 15702135 DOI: 10.1038/sj.npp.1300687  1
2005 McCracken CB, Patel KM, Vrana KE, Paul DL, Roberts DC. Amphetamine withdrawal produces region-specific and time-dependent changes in connexin36 expression in rat brain. Synapse (New York, N.Y.). 56: 39-44. PMID 15700285 DOI: 10.1002/syn.20127  1
2005 Liu Y, Roberts DC, Morgan D. Effects of extended-access self-administration and deprivation on breakpoints maintained by cocaine in rats. Psychopharmacology. 179: 644-51. PMID 15650844 DOI: 10.1007/s00213-004-2089-y  1
2005 Ward SJ, Morgan D, Roberts DC. Comparison of the reinforcing effects of cocaine and cocaine/heroin combinations under progressive ratio and choice schedules in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 286-95. PMID 15578009 DOI: 10.1038/sj.npp.1300560  1
2005 Morgan D, Smith MA, Roberts DC. Binge self-administration and deprivation produces sensitization to the reinforcing effects of cocaine in rats. Psychopharmacology. 178: 309-16. PMID 15322729 DOI: 10.1007/s00213-004-1992-6  1
2004 Mateo Y, Budygin EA, Morgan D, Roberts DC, Jones SR. Fast onset of dopamine uptake inhibition by intravenous cocaine. The European Journal of Neuroscience. 20: 2838-42. PMID 15548229 DOI: 10.1111/j.1460-9568.2004.03736.x  1
2004 Morgan D, Roberts DC. Sensitization to the reinforcing effects of cocaine following binge-abstinent self-administration. Neuroscience and Biobehavioral Reviews. 27: 803-12. PMID 15019429 DOI: 10.1016/j.neubiorev.2003.11.004  1
2004 Smith MA, Yancey DL, Morgan D, Liu Y, Froestl W, Roberts DC. Effects of positive allosteric modulators of the GABAB receptor on cocaine self-administration in rats. Psychopharmacology. 173: 105-11. PMID 14712341 DOI: 10.1007/s00213-003-1706-5  1
2004 Lynch WJ, Roberts DC. Effects of cocaine self-administration on food-reinforced responding using a discrete trial procedure in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 669-75. PMID 14694351 DOI: 10.1038/sj.npp.1300363  1
2003 Ward SJ, Martin TJ, Roberts DC. Beta-funaltrexamine affects cocaine self-administration in rats responding on a progressive ratio schedule of reinforcement. Pharmacology, Biochemistry, and Behavior. 75: 301-7. PMID 12873620 DOI: 10.1016/S0091-3057(03)00087-X  1
2003 Roberts DC, Jungersmith KR, Phelan R, Gregg TM, Davies HM. Effect of HD-23, a potent long acting cocaine-analog, on cocaine self-administration in rats. Psychopharmacology. 167: 386-92. PMID 12669183 DOI: 10.1007/s00213-003-1424-z  1
2003 Bennett SA, Roberts DC. Analysis of protein expression in brain tissue by ELISA. Methods in Molecular Medicine. 79: 283-95. PMID 12506704  1
2002 Freeman WM, Brebner K, Patel KM, Lynch WJ, Roberts DC, Vrana KE. Repeated cocaine self-administration causes multiple changes in rat frontal cortex gene expression. Neurochemical Research. 27: 1181-92. PMID 12462416 DOI: 10.1023/A:1020929526688  1
2002 Morgan D, Brebner K, Lynch WJ, Roberts DC. Increases in the reinforcing efficacy of cocaine after particular histories of reinforcement. Behavioural Pharmacology. 13: 389-96. PMID 12394415  1
2002 Brebner K, Childress AR, Roberts DC. A potential role for GABA(B) agonists in the treatment of psychostimulant addiction. Alcohol and Alcoholism (Oxford, Oxfordshire). 37: 478-84. PMID 12217943  1
2002 Roberts DC, Brebner K, Vincler M, Lynch WJ. Patterns of cocaine self-administration in rats produced by various access conditions under a discrete trials procedure. Drug and Alcohol Dependence. 67: 291-9. PMID 12127200 DOI: 10.1016/S0376-8716(02)00083-2  1
2002 Freeman WM, Brebner K, Lynch WJ, Patel KM, Robertson DJ, Roberts DC, Vrana KE. Changes in rat frontal cortex gene expression following chronic cocaine. Brain Research. Molecular Brain Research. 104: 11-20. PMID 12117546 DOI: 10.1016/S0169-328X(02)00197-3  1
2002 Brebner K, Froestl W, Roberts DC. The GABA(B) antagonist CGP56433A attenuates the effect of baclofen on cocaine but not heroin self-administration in the rat. Psychopharmacology. 160: 49-55. PMID 11862373 DOI: 10.1007/s00213-001-0952-7  1
2002 Cousins MS, Roberts DC, de Wit H. GABA(B) receptor agonists for the treatment of drug addiction: a review of recent findings. Drug and Alcohol Dependence. 65: 209-20. PMID 11841892 DOI: 10.1016/S0376-8716(01)00163-6  1
2001 Freeman WM, Brebner K, Lynch WJ, Robertson DJ, Roberts DC, Vrana KE. Cocaine-responsive gene expression changes in rat hippocampus. Neuroscience. 108: 371-80. PMID 11738252 DOI: 10.1016/S0306-4522(01)00432-8  1
2001 Brennan K, Roberts DC, Anisman H, Merali Z. Individual differences in sucrose consumption in the rat: motivational and neurochemical correlates of hedonia. Psychopharmacology. 157: 269-76. PMID 11605082 DOI: 10.1007/s002130100805  1
2000 Brebner K, Phelan R, Roberts DC. Intra-VTA baclofen attenuates cocaine self-administration on a progressive ratio schedule of reinforcement. Pharmacology, Biochemistry, and Behavior. 66: 857-62. PMID 10973526 DOI: 10.1016/S0091-3057(00)00286-0  1
2000 Roberts DC, Brebner K. GABA modulation of cocaine self-administration. Annals of the New York Academy of Sciences. 909: 145-58. PMID 10911928  1
2000 Brebner K, Phelan R, Roberts DC. Effect of baclofen on cocaine self-administration in rats reinforced under fixed-ratio 1 and progressive-ratio schedules. Psychopharmacology. 148: 314-21. PMID 10755745  1
1999 Brebner K, Froestl W, Andrews M, Phelan R, Roberts DC. The GABA(B) agonist CGP 44532 decreases cocaine self-administration in rats: demonstration using a progressive ratio and a discrete trials procedure. Neuropharmacology. 38: 1797-804. PMID 10587095 DOI: 10.1016/S0028-3908(99)00094-5  1
1999 Bennett SA, Arnold JM, Chen J, Stenger J, Paul DL, Roberts DC. Long-term changes in connexin32 gap junction protein and mRNA expression following cocaine self-administration in rats. The European Journal of Neuroscience. 11: 3329-38. PMID 10510198 DOI: 10.1046/j.1460-9568.1999.00752.x  1
1999 Roberts DC, Phelan R, Hodges LM, Hodges MM, Bennett B, Childers S, Davies H. Self-administration of cocaine analogs by rats. Psychopharmacology. 144: 389-97. PMID 10435412 DOI: 10.1007/s002130051022  1
1998 Bennett SA, Chen J, Pappas BA, Roberts DC, Tenniswood M. Platelet activating factor receptor expression is associated with neuronal apoptosis in an in vivo model of excitotoxicity. Cell Death and Differentiation. 5: 867-75. PMID 10203694 DOI: 10.1038/sj.cdd.4400434  1
1997 Arnold JM, Roberts DC. A critique of fixed and progressive ratio schedules used to examine the neural substrates of drug reinforcement. Pharmacology, Biochemistry, and Behavior. 57: 441-7. PMID 9218268  1
1997 Roberts DC, Andrews MM. Baclofen suppression of cocaine self-administration: demonstration using a discrete trials procedure. Psychopharmacology. 131: 271-7. PMID 9203238 DOI: 10.1007/s002130050293  1
1996 Ranaldi R, Roberts DC. Initiation, maintenance and extinction of cocaine self-administration with and without conditioned reward. Psychopharmacology. 128: 89-96. PMID 8944411 DOI: 10.1007/s002130050114  1
1996 Ranaldi R, French E, Roberts DC. Systemic pretreatment with MK-801 (dizocilpine) increases breaking points for self-administration of cocaine on a progressive-ratio schedule in rats. Psychopharmacology. 128: 83-8. PMID 8944410 DOI: 10.1007/s002130050113  1
1996 Roberts DC, Andrews MM, Vickers GJ. Baclofen attenuates the reinforcing effects of cocaine in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 417-23. PMID 8887996 DOI: 10.1016/0893-133X(96)00002-4  1
1996 McGregor A, Baker G, Roberts DC. Effect of 6-hydroxydopamine lesions of the medial prefrontal cortex on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement. Pharmacology, Biochemistry, and Behavior. 53: 5-9. PMID 8848459  1
1996 Richardson NR, Roberts DC. Progressive ratio schedules in drug self-administration studies in rats: a method to evaluate reinforcing efficacy. Journal of Neuroscience Methods. 66: 1-11. PMID 8794935 DOI: 10.1016/0165-0270(95)00153-0  1
1995 French ED, Lopez M, Peper S, Kamenka JM, Roberts DC. A comparison of the reinforcing efficacy of PCP, the PCP derivatives TCP and BTCP, and cocaine using a progressive ratio schedule in the rat. Behavioural Pharmacology. 6: 223-228. PMID 11224330  0.04
1995 Smith A, Roberts DC. Oral self-administration of sweetened nicotine solutions by rats. Psychopharmacology. 120: 341-6. PMID 8524982 DOI: 10.1007/BF02311182  1
1995 McGregor A, Roberts DC. Effect of medial prefrontal cortex injections of SCH 23390 on intravenous cocaine self-administration under both a fixed and progressive ratio schedule of reinforcement. Behavioural Brain Research. 67: 75-80. PMID 7748503  1
1995 Bennett SA, Stevenson B, Staines WA, Roberts DC. Periodic acid-Schiff (PAS)-positive deposits in brain following kainic acid-induced seizures: relationships to fos induction, neuronal necrosis, reactive gliosis, and blood-brain barrier breakdown. Acta Neuropathologica. 89: 126-38. PMID 7732785 DOI: 10.1007/BF00296356  1
1995 Daunais JB, Roberts DC, McGinty JF. Short-term cocaine self administration alters striatal gene expression. Brain Research Bulletin. 37: 523-7. PMID 7633900 DOI: 10.1016/0361-9230(95)00049-K  1
1995 Smith A, Piercey M, Roberts DC. Effect of (-)-DS 121 and (+)-UH 232 on cocaine self-administration in rats. Psychopharmacology. 120: 93-8. PMID 7480540 DOI: 10.1007/BF02246149  1
1994 McGregor A, Baker G, Roberts DC. Effect of 6-hydroxydopamine lesions of the amygdala on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement. Brain Research. 646: 273-8. PMID 8069674  1
1994 Richardson NR, Smith AM, Roberts DC. A single injection of either flupenthixol decanoate or haloperidol decanoate produces long-term changes in cocaine self-administration in rats. Drug and Alcohol Dependence. 36: 23-5. PMID 7988355 DOI: 10.1016/0376-8716(94)90005-1  1
1994 Nader K, Bechara A, Roberts DC, van der Kooy D. Neuroleptics block high- but not low-dose heroin place preferences: further evidence for a two-system model of motivation. Behavioral Neuroscience. 108: 1128-38. PMID 7893405 DOI: 10.1037/0735-7044.108.6.1128  1
1994 Roberts DC, Loh EA, Baker GB, Vickers G. Lesions of central serotonin systems affect responding on a progressive ratio schedule reinforced either by intravenous cocaine or by food. Pharmacology, Biochemistry, and Behavior. 49: 177-82. PMID 7816870 DOI: 10.1016/0091-3057(94)90473-1  1
1993 Loh EA, Smith AM, Roberts DC. Evaluation of response perseveration of rats in the radial arm maze following reinforcing and nonreinforcing drugs. Pharmacology, Biochemistry, and Behavior. 44: 735-40. PMID 8451275 DOI: 10.1016/0091-3057(93)90192-V  1
1993 McGregor A, Lacosta S, Roberts DC. L-tryptophan decreases the breaking point under a progressive ratio schedule of intravenous cocaine reinforcement in the rat. Pharmacology, Biochemistry, and Behavior. 44: 651-5. PMID 8451268  1
1993 Lacosta S, Roberts DC. MDL 72222, ketanserin, and methysergide pretreatments fail to alter breaking points on a progressive ratio schedule reinforced by intravenous cocaine. Pharmacology, Biochemistry, and Behavior. 44: 161-5. PMID 8430119  1
1993 Richardson NR, Piercey MF, Svensson K, Collins RJ, Myers JE, Roberts DC. Antagonism of cocaine self-administration by the preferential dopamine autoreceptor antagonist, (+)-AJ 76. Brain Research. 619: 15-21. PMID 8374772 DOI: 10.1016/0006-8993(93)91591-F  1
1993 Fitch TE, Roberts DC. The effects of dose and access restrictions on the periodicity of cocaine self-administration in the rat. Drug and Alcohol Dependence. 33: 119-28. PMID 8261876  0.01
1993 McGregor A, Roberts DC. Dopaminergic antagonism within the nucleus accumbens or the amygdala produces differential effects on intravenous cocaine self-administration under fixed and progressive ratio schedules of reinforcement. Brain Research. 624: 245-52. PMID 8252397  1
1993 Daunais JB, Roberts DC, McGinty JF. Cocaine self-administration increases preprodynorphin, but not c-fos, mRNA in rat striatum. Neuroreport. 4: 543-6. PMID 8099817  1
1993 Roberts DC, Bennett SA. Heroin self-administration in rats under a progressive ratio schedule of reinforcement. Psychopharmacology. 111: 215-8. PMID 7870955  1
1993 Roberts DC. Self-administration of GBR 12909 on a fixed ratio and progressive ratio schedule in rats. Psychopharmacology. 111: 202-6. PMID 7870953  0.01
1992 Loh EA, Fitch T, Vickers G, Roberts DC. Clozapine increases breaking points on a progressive-ratio schedule reinforced by intravenous cocaine. Pharmacology, Biochemistry, and Behavior. 42: 559-62. PMID 1409791  1
1991 Richardson NR, Roberts DC. Fluoxetine pretreatment reduces breaking points on a progressive ratio schedule reinforced by intravenous cocaine self-administration in the rat. Life Sciences. 49: 833-40. PMID 1875791 DOI: 10.1016/0024-3205(91)90248-A  1
1991 Markert LE, Roberts DC. 3,4-Methylenedioxyamphetamine (MDA) self-administration and neurotoxicity. Pharmacology, Biochemistry, and Behavior. 39: 569-74. PMID 1784586  0.01
1990 Loh EA, Roberts DC. Break-points on a progressive ratio schedule reinforced by intravenous cocaine increase following depletion of forebrain serotonin. Psychopharmacology. 101: 262-6. PMID 2349367  1
1989 Bialik RJ, Smythe JW, Sardelis M, Roberts DC. Adrenal demedullation blocks and brain norepinephrine depletion potentiates the hyperglycemic response to a variety of stressors. Brain Research. 502: 88-98. PMID 2819460  1
1989 Roberts DC, Bennett SA, Vickers GJ. The estrous cycle affects cocaine self-administration on a progressive ratio schedule in rats. Psychopharmacology. 98: 408-11. PMID 2501818  1
1989 Roberts DC. Breaking points on a progressive ratio schedule reinforced by intravenous apomorphine increase daily following 6-hydroxydopamine lesions of the nucleus accumbens. Pharmacology, Biochemistry, and Behavior. 32: 43-7. PMID 2499893  0.01
1989 Roberts DC, Loh EA, Vickers G. Self-administration of cocaine on a progressive ratio schedule in rats: dose-response relationship and effect of haloperidol pretreatment. Psychopharmacology. 97: 535-8. PMID 2498950  1
1988 Bialik RJ, Smythe JW, Roberts DC. Alpha 2-adrenergic receptors mediate the increase in blood glucose levels induced by epinephrine and brief footshock stress. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 12: 307-14. PMID 2838868  1
1987 Roberts DC, Dalton JC, Vickers GJ. Increased self-administration of cocaine following haloperidol: effect of ovariectomy, estrogen replacement, and estrous cycle. Pharmacology, Biochemistry, and Behavior. 26: 37-43. PMID 3562496  1
1987 Roberts DC, Vickers G. The effect of haloperidol on cocaine self-administration is augmented with repeated administrations. Psychopharmacology. 93: 526-8. PMID 3124187  1
1986 Dalton JC, Vickers GJ, Roberts DC. Increased self-administration of cocaine following haloperidol: sex-dependent effects of the antiestrogen tamoxifen. Pharmacology, Biochemistry, and Behavior. 25: 497-501. PMID 3774817  1
1985 Zito KA, Vickers G, Roberts DC. Disruption of cocaine and heroin self-administration following kainic acid lesions of the nucleus accumbens. Pharmacology, Biochemistry, and Behavior. 23: 1029-36. PMID 3936058 DOI: 10.1016/0091-3057(85)90110-8  1
1985 Dalton JC, Roberts DC, McIntyre DC. Supersensitivity to the anticonvulsant and proconvulsant activity of clonidine following noradrenaline depletion induced by 6-hydroxydopamine. Psychopharmacology. 85: 319-22. PMID 3923518 DOI: 10.1007/BF00428195  1
1985 Hrdina PD, Pappas BA, Roberts DC, Bialik RJ, Ryan CL. Relationship between levels and uptake of serotonin and high affinity [3H]imipramine recognition sites in the rat brain. Canadian Journal of Physiology and Pharmacology. 63: 1239-44. PMID 3000552  1
1985 van der Kooy D, Zito KA, Roberts DC. Evidence on the retrograde neurotoxicity of doxorubicin. Neuroscience Letters. 53: 215-9. PMID 2580250 DOI: 10.1016/0304-3940(85)90188-0  1
1984 Koob GF, Thatcher-Britton K, Britton DR, Roberts DC, Bloom FE. Destruction of the locus coeruleus or the dorsal NE bundle does not alter the release of punished responding by ethanol and chlordiazepoxide. Physiology & Behavior. 33: 479-85. PMID 6542682  1
1984 Zito KA, Vickers G, Telford L, Roberts DC. Experimentally induced glucose intolerance increases oral ethanol intake in rats. Alcohol (Fayetteville, N.Y.). 1: 257-61. PMID 6536290 DOI: 10.1016/0741-8329(84)90046-6  1
1984 Roberts VJ, Singhal RL, Roberts DC. Corticosterone prevents the increase in noradrenaline-stimulated adenyl cyclase activity in rat hippocampus following adrenalectomy or metopirone. European Journal of Pharmacology. 103: 235-40. PMID 6489443  0.01
1984 Bialik RJ, Pappas BA, Roberts DC. Deficits in conditioned avoidance responding following adrenalectomy and central norepinephrine depletion are dependent on postsurgical recovery period and phase of the diurnal cycle. Behavioral Neuroscience. 98: 847-57. PMID 6487418 DOI: 10.1037//0735-7044.98.5.847  1
1984 Bialik RJ, Pappas BA, Roberts DC. Neonatal 6-hydroxydopamine prevents adaptation to chemical disruption of the pituitary-adrenal system in the rat. Hormones and Behavior. 18: 12-21. PMID 6323301 DOI: 10.1016/0018-506X(84)90046-1  1
1984 Roberts DC, Vickers G. Atypical neuroleptics increase self-administration of cocaine: an evaluation of a behavioural screen for antipsychotic activity. Psychopharmacology. 82: 135-9. PMID 6141584  1
1983 Kelly PH, Roberts DC. Effects of amphetamine and apomorphine on locomotor activity after 6-OHDA and electrolytic lesions of the nucleus accumbens septi. Pharmacology, Biochemistry, and Behavior. 19: 137-43. PMID 6413984  0.01
1983 Tombaugh TN, Pappas BA, Roberts DC, Vickers GJ, Szostak C. Failure to replicate the dorsal bundle extinction effect: telencephalic norepinephrine depletion does not reliably increase resistance to extinction but does augment gustatory neophobia. Brain Research. 261: 231-42. PMID 6403201 DOI: 10.1016/0006-8993(83)90626-1  1
1983 Robbins TW, Roberts DC, Koob GF. Effects of d-amphetamine and apomorphine upon operant behavior and schedule-induced licking in rats with 6-hydroxydopamine-induced lesions of the nucleus accumbens. The Journal of Pharmacology and Experimental Therapeutics. 224: 662-73. PMID 6402587  1
1983 McIntyre DC, Roberts DC. Long-term reduction in beta-adrenergic receptor binding after amygdala kindling in rats. Experimental Neurology. 82: 17-24. PMID 6313421 DOI: 10.1016/0014-4886(83)90239-X  1
1982 Roberts DC, Koob GF. Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats. Pharmacology, Biochemistry, and Behavior. 17: 901-4. PMID 6817350 DOI: 10.1016/0091-3057(82)90469-5  1
1982 Strecker RE, Roberts DC, Koob GF. Apomorphine-induced facilitation of intracranial self-stimulation following dopamine denervation of the nucleus accumbens. Pharmacology, Biochemistry, and Behavior. 17: 1015-8. PMID 6817349 DOI: 10.1016/0091-3057(82)90487-7  1
1981 Arnsten AF, Segal DS, Loughlin SE, Roberts DC. Evidence for an interaction of opioid and noradrenergic locus coeruleus systems in the regulation of environmental stimulus-directed behavior. Brain Research. 222: 351-63. PMID 7284783 DOI: 10.1016/0006-8993(81)91038-6  1
1981 Roberts DC, Bloom FE. Adrenal steroid-induced changes in beta-adrenergic receptor binding in rat hippocampus. European Journal of Pharmacology. 74: 37-41. PMID 6274649  1
1980 Roberts DC, Koob GF, Klonoff P, Fibiger HC. Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens. Pharmacology, Biochemistry, and Behavior. 12: 781-7. PMID 7393973  1
1979 Roberts DC, McCaughran JA, Fibiger HC. Behavioural effects of 6-hydroxydopamine-induced depletion of spinal noradrenaline. Canadian Journal of Physiology and Pharmacology. 57: 1223-8. PMID 519524  1
1979 Mason ST, Roberts DC, Fibiger HC. Interaction of brain noradrenaline and the pituitary-adrenal axis in learning and extinction. Pharmacology, Biochemistry, and Behavior. 10: 11-6. PMID 441087  1
1978 Roberts DC, Mason ST, Fibiger HC. Selective depletion of spinal noradrenaline abolishes post-decapitation convulsions. Life Sciences. 23: 2411-3. PMID 745520  1
1978 Pappas BA, Saari M, Peters DA, Roberts DC, Fibiger HC. Neonatal systemic 6-hydroxydopamine and dorsal tegmental bundle lesion: comparison of effects on CSN norepinephrine and the postdecapitation reflex. Brain Research. 155: 205-8. PMID 688013 DOI: 10.1016/0022-2836(78)90301-7  1
1978 Mason ST, Roberts DC, Fibiger HC. Noradrenaline and neophobia. Physiology & Behavior. 21: 353-61. PMID 570276  1
1978 Roberts DC, Mason ST, Fibiger HC. 6-OHDA lesion to the dorsal noradrenergic bundle alters morphine-induced locomotor activity and catalepsy. European Journal of Pharmacology. 52: 209-14. PMID 569587  1
1978 Mason ST, Roberts DC, Fibiger HC. Noradrenergic influences on catalepsy. Psychopharmacology. 60: 53-7. PMID 104346  1
1977 Roberts DC, Fibiger HC. Lesions of the dorsal noradrenergic projection attenuate morphine- but not amphetamine-induced conditioned taste aversion. Psychopharmacology. 55: 183-6. PMID 414277  1
1977 Roberts DC, Fibiger HC. Evidence for interactions between central noradrenergic neurons and adrenal hormones in learning and memory. Pharmacology, Biochemistry, and Behavior. 7: 191-4. PMID 200962  1
1977 Roberts DC, Corcoran ME, Fibiger HC. On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine. Pharmacology, Biochemistry, and Behavior. 6: 615-20. PMID 122445 DOI: 10.1016/0091-3057(77)90084-3  1
1976 Roberts DC, Fibiger HC. Conditioned taste aversion induced by diethyldithiocarbamate (DDC). Neuroscience Letters. 2: 339-42. PMID 19604856  1
1976 Roberts DC, Price MT, Fibiger HC. The dorsal tegmental noradrenergic projection: an analysis of its role in maze learning. Journal of Comparative and Physiological Psychology. 90: 363-72. PMID 1270644  1
1975 Roberts DC, Fibiger HC. Attenuation of amphetamine-induced conditioned taste aversion following intraventricular 6-hydroxydopamine. Neuroscience Letters. 1: 343-7. PMID 19604802  1
1975 Roberts DC, Zis AP, Fibiger HC. Ascending catecholamine pathways and amphetamine-induced locomotor activity: importance of dopamine and apparent non-involvement of norepinephrine. Brain Research. 93: 441-54. PMID 1236760  1
Show low-probability matches.