Year |
Citation |
Score |
2022 |
Pang AH, Green KD, Chandrika NT, Garzan A, Punetha A, Holbrook SYL, Willby MJ, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Discovery of substituted benzyloxy-benzylamine inhibitors of acetyltransferase Eis and their anti-mycobacterial activity. European Journal of Medicinal Chemistry. 242: 114698. PMID 36037791 DOI: 10.1016/j.ejmech.2022.114698 |
0.617 |
|
2022 |
Green KD, Pang AH, Thamban Chandrika N, Garzan A, Baughn AD, Tsodikov OV, Garneau-Tsodikova S. Discovery and Optimization of 6-(1-Substituted pyrrole-2-yl)--triazine Containing Compounds as Antibacterial Agents. Acs Infectious Diseases. 8: 757-767. PMID 35239306 DOI: 10.1021/acsinfecdis.1c00450 |
0.572 |
|
2021 |
Punetha A, Green KD, Garzan A, Thamban Chandrika N, Willby MJ, Pang AH, Hou C, Holbrook SYL, Krieger K, Posey JE, Parish T, Tsodikov OV, Garneau-Tsodikova S. Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from to overcome kanamycin resistance. Rsc Medicinal Chemistry. 12: 1894-1909. PMID 34825186 DOI: 10.1039/d1md00239b |
0.607 |
|
2021 |
Zhang S, Garzan A, Haese N, Bostwick R, Martinez-Gzegozewska Y, Rasmussen L, Streblow DN, Haise MT, Pathak AK, Augelli-Szafran CE, Wu M. Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One. 16: e0245013. PMID 33482665 DOI: 10.1371/journal.pone.0245013 |
0.301 |
|
2018 |
Scutigliani EM, Scholl ER, Grootemaat AE, Khanal S, Kochan JA, Krawczyk PM, Reits EA, Garzan A, Ngo HX, Green KD, Garneau-Tsodikova S, Ruijter JM, van Veen HA, van der Wel NN. Interfering With DNA Decondensation as a Strategy Against Mycobacteria. Frontiers in Microbiology. 9: 2034. PMID 30233521 DOI: 10.3389/Fmicb.2018.02034 |
0.583 |
|
2018 |
Ngo HX, Green KD, Gajadeera CS, Willby MJ, Holbrook SYL, Hou C, Garzan A, Mayhoub AS, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Potent 1,2,4-Triazino[5,6 b]indole-3-thioether Inhibitors of the Kanamycin Resistance Enzyme Eis from Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 29601176 DOI: 10.1021/Acsinfecdis.8B00074 |
0.644 |
|
2018 |
Mori S, Pang AH, Lundy TA, Garzan A, Tsodikov OV, Garneau-Tsodikova S. Structural basis for backbone N-methylation by an interrupted adenylation domain. Nature Chemical Biology. PMID 29556104 DOI: 10.1038/S41589-018-0014-7 |
0.614 |
|
2017 |
Mori S, Garzan A, Tsodikov OV, Garneau-Tsodikova S. Deciphering Nature's Intricate Way of N,S-Dimethylating l-Cysteine: Sequential Action of Two Bifunctional Adenylation Domains. Biochemistry. PMID 29112395 DOI: 10.1021/Acs.Biochem.7B00980 |
0.601 |
|
2017 |
Holbrook SYL, Garzan A, Dennis EK, Shrestha SK, Garneau-Tsodikova S. Repurposing antipsychotic drugs into antifungal agents: Synergistic combinations of azoles and bromperidol derivatives in the treatment of various fungal infections. European Journal of Medicinal Chemistry. 139: 12-21. PMID 28797882 DOI: 10.1016/J.Ejmech.2017.07.030 |
0.574 |
|
2017 |
Mori S, Shrestha SK, Fernández J, Álvarez San Millán M, Garzan A, Al-Mestarihi AH, Lombó F, Garneau-Tsodikova S. Activation and loading of the starter unit during thiocoraline biosynthesis. Biochemistry. PMID 28762729 DOI: 10.1021/Acs.Biochem.7B00661 |
0.662 |
|
2017 |
Shrestha SK, Garzan A, Garneau-Tsodikova S. Novel alkylated azoles as potent antifungals. European Journal of Medicinal Chemistry. 133: 309-318. PMID 28395217 DOI: 10.1016/J.Ejmech.2017.03.075 |
0.614 |
|
2017 |
Garzan A, Willby MJ, Ngo HX, Gajadeera CS, Green KD, Holbrook SY, Hou C, Posey JE, Tsodikov OV, Garneau-Tsodikova S. Combating Eis-mediated kanamycin resistance of M. tuber-culosis by novel pyrrolo[1,5-a]pyrazine-based Eis inhibitors. Acs Infectious Diseases. PMID 28192916 DOI: 10.1021/Acsinfecdis.6B00193 |
0.641 |
|
2016 |
Garzan A, Willby MJ, Green KD, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Discovery and Optimization of Two Eis Inhibitor Families as Kanamycin Adjuvants against Drug-Resistant M. tuberculosis. Acs Medicinal Chemistry Letters. 7: 1219-1221. PMID 27994767 DOI: 10.1021/Acsmedchemlett.6B00261 |
0.611 |
|
2016 |
Garzan A, Willby MJ, Green KD, Gajadeera CS, Hou C, Tsodikov OV, Posey JE, Garneau-Tsodikova S. Sulfonamide-Based Inhibitors of Aminoglycoside Acetyltransferase Eis Abolish Resistance to Kanamycin in Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 59: 10619-10628. PMID 27933949 DOI: 10.1021/Acs.Jmedchem.6B01161 |
0.615 |
|
2016 |
Pang AH, Garzan A, Larsen MJ, McQuade TJ, Garneau-Tsodikova S, Tsodikov OV. Discovery of allosteric and selective inhibitors of inorganic pyrophosphatase from Mycobacterium tuberculosis. Acs Chemical Biology. PMID 27622287 DOI: 10.1021/Acschembio.6B00510 |
0.657 |
|
2016 |
LaPorte MG, Wang Z, Colombo R, Garzan A, Peshkov VA, Liang M, Johnston PA, Schurdak ME, Sen M, Camarco DP, Hua Y, Pollock NI, Lazo JS, Grandis JR, Wipf P, et al. Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27381083 DOI: 10.1016/J.Bmcl.2016.06.017 |
0.39 |
|
2015 |
Al-Mestarihi AH, Garzan A, Kim JM, Garneau-Tsodikova S. Enzymatic Evidence for a Revised Congocidine Biosynthetic Pathway. Chembiochem : a European Journal of Chemical Biology. 16: 1307-13. PMID 25958990 DOI: 10.1002/Cbic.201402711 |
0.673 |
|
2005 |
Firouzabadi H, Iranpoor N, Garzan A. Pronounced catalytic effect of micellar solution of sodium dodecyl sulfate (SDS) for regioselective iodination of aromatic compounds with a sodium iodide/cerium(IV) trihydroxide hydroperoxide system Advanced Synthesis and Catalysis. 347: 1925-1928. DOI: 10.1002/Adsc.200505222 |
0.322 |
|
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