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Chun Kit Kwok, Ph.D - Publications

Affiliations: 
2009-2014 Chemistry Pennsylvania State University, State College, PA, United States 
 2014-2016 Chemistry University of Cambridge, Cambridge, England, United Kingdom 
 2016-2017 Biology and Chemistry City University of Hong Kong, Kowloon, Hong Kong 
 2017- Chemistry City University of Hong Kong, Kowloon, Hong Kong 
Area:
Nucleic Acids, Biological Sciences, Genetics, Epigenetics
Website:
http://kitkwok.weebly.com
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56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lyu K, Kwok CK. RNA G-quadruplex (rG4) structure detection using RTS and SHALiPE assays. Methods in Enzymology. 691: 63-80. PMID 37914452 DOI: 10.1016/bs.mie.2023.06.003  0.631
2023 Ji D, Yuan JH, Chen SB, Tan JH, Kwok CK. Selective targeting of parallel G-quadruplex structure using L-RNA aptamer. Nucleic Acids Research. PMID 37870474 DOI: 10.1093/nar/gkad900  0.398
2023 Mou X, Kwok CK. Peptides Selected by G4-mRNA Display-Seq Enable RNA G-Quadruplex Recognition and Gene Regulation. Journal of the American Chemical Society. 145: 18693-18697. PMID 37582058 DOI: 10.1021/jacs.3c04534  0.329
2023 Lyu K, Kwok CK. A G-quadruplex structure in microRNA interferes with messenger RNA recognition and controls gene expression. Chemical Communications (Cambridge, England). 59: 8230-8233. PMID 37309572 DOI: 10.1039/d3cc01549a  0.48
2023 Guo W, Ji D, Kinghorn AB, Chen F, Pan Y, Li X, Li Q, Huck WTS, Kwok CK, Shum HC. Tuning Material States and Functionalities of G-Quadruplex-Modulated RNA-Peptide Condensates. Journal of the American Chemical Society. PMID 36689740 DOI: 10.1021/jacs.2c11362  0.492
2022 Zhao J, Chow EY, Yeung PY, Zhang QC, Chan TF, Kwok CK. Enhanced transcriptome-wide RNA G-quadruplex sequencing for low RNA input samples with rG4-seq 2.0. Bmc Biology. 20: 257. PMID 36372875 DOI: 10.1186/s12915-022-01448-3  0.639
2022 Lyu K, Chen SB, Chow EY, Zhao H, Yuan JH, Cai M, Shi J, Chan TF, Tan JH, Kwok CK. An RNA G-Quadruplex Structure within the ADAR 5'UTR Interacts with DHX36 Helicase to Regulate Translation. Angewandte Chemie (International Ed. in English). PMID 36300875 DOI: 10.1002/anie.202203553  0.605
2022 Yang X, Yu H, Duncan S, Zhang Y, Cheema J, Liu H, Benjamin Miller J, Zhang J, Kwok CK, Zhang H, Ding Y. RNA G-quadruplex structure contributes to cold adaptation in plants. Nature Communications. 13: 6224. PMID 36266343 DOI: 10.1038/s41467-022-34040-y  0.801
2022 Dumetz F, Enright AJ, Zhao J, Kwok CK, Merrick CJ. The in vivo RNA structurome of the malaria parasite Plasmodium falciparum, a protozoan with an A/U-rich transcriptome. Plos One. 17: e0270863. PMID 36048819 DOI: 10.1371/journal.pone.0270863  0.587
2022 Zhao H, Wong HY, Ji D, Lyu K, Kwok CK. Novel L-RNA Aptamer Controls Gene Expression in Cells by Targeting RNA G-Quadruplex Structure. Acs Applied Materials & Interfaces. PMID 35762921 DOI: 10.1021/acsami.2c06390  0.465
2022 Xu B, Zhu Y, Cao C, Chen H, Jin Q, Li G, Ma J, Yang SL, Zhao J, Zhu J, Ding Y, Fang X, Jin Y, Kwok CK, Ren A, et al. Recent advances in RNA structurome. Science China. Life Sciences. PMID 35717434 DOI: 10.1007/s11427-021-2116-2  0.824
2022 Chen X, Xue G, Zhao J, Zhang Y, Zhang S, Wang W, Li Y, Yuan J, He L, Chan CY, Liu Y, Chen W, Zhao Y, Hu P, Sun H, ... Kwok CK, et al. Lockd promotes myoblast proliferation and muscle regeneration via binding with DHX36 to facilitate 5' UTR rG4 unwinding and Anp32e translation. Cell Reports. 39: 110927. PMID 35675771 DOI: 10.1016/j.celrep.2022.110927  0.319
2022 Georgakopoulos-Soares I, Parada GE, Wong HY, Medhi R, Furlan G, Munita R, Miska EA, Kwok CK, Hemberg M. Alternative splicing modulation by G-quadruplexes. Nature Communications. 13: 2404. PMID 35504902 DOI: 10.1038/s41467-022-30071-7  0.519
2022 Umar MI, Chan CY, Kwok CK. Development of RNA G-quadruplex (rG4)-targeting L-RNA aptamers by rG4-SELEX. Nature Protocols. PMID 35444329 DOI: 10.1038/s41596-022-00679-6  0.571
2022 Feng H, Kwok CK. Spectroscopic analysis reveals the effect of hairpin loop formation on G-quadruplex structures. Rsc Chemical Biology. 3: 431-435. PMID 35441140 DOI: 10.1039/d2cb00045h  0.371
2022 Mou X, Liew SW, Kwok CK. Identification and targeting of G-quadruplex structures in MALAT1 long non-coding RNA. Nucleic Acids Research. 50: 397-410. PMID 34904666 DOI: 10.1093/nar/gkab1208  0.546
2021 Dumetz F, Chow EY, Harris LM, Liew SW, Jensen A, Umar MI, Chung B, Chan TF, Merrick CJ, Kwok CK. G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum. Nucleic Acids Research. PMID 34792144 DOI: 10.1093/nar/gkab1095  0.549
2021 Ji D, Lyu K, Zhao H, Kwok CK. Circular L-RNA aptamer promotes target recognition and controls gene activity. Nucleic Acids Research. PMID 34233000 DOI: 10.1093/nar/gkab593  0.456
2021 Lyu K, Chow EY, Mou X, Chan TF, Kwok CK. RNA G-quadruplexes (rG4s): genomics and biological functions. Nucleic Acids Research. PMID 33772593 DOI: 10.1093/nar/gkab187  0.551
2020 Mou X, Kwok CK. Effect of RNA sequence context and stereochemistry on G-quadruplex-RHAU53 interaction. Biochemical and Biophysical Research Communications. PMID 33041003 DOI: 10.1016/j.bbrc.2020.09.045  0.412
2020 Umar MI, Kwok CK. Specific suppression of D-RNA G-quadruplex-protein interaction with an L-RNA aptamer. Nucleic Acids Research. PMID 32976590 DOI: 10.1093/nar/gkaa759  0.438
2020 Yang X, Cheema J, Zhang Y, Deng H, Duncan S, Umar MI, Zhao J, Liu Q, Cao X, Kwok CK, Ding Y. RNA G-quadruplex structures exist and function in vivo in plants. Genome Biology. 21: 226. PMID 32873317 DOI: 10.1186/S13059-020-02142-9  0.835
2020 Ji D, Juhas M, Tsang CM, Kwok CK, Li Y, Zhang Y. Discovery of G-quadruplex-forming sequences in SARS-CoV-2. Briefings in Bioinformatics. PMID 32484220 DOI: 10.1093/Bib/Bbaa114  0.56
2020 Chow EY, Lyu K, Kwok CK, Chan TF. rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments. Rna Biology. 1-15. PMID 32338139 DOI: 10.1080/15476286.2020.1740470  0.523
2020 Yeung PY, Zhao J, Chow EY, Mou X, Hong H, Chen L, Chan TF, Kwok CK. Author Correction: Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing. Scientific Reports. 10: 3874. PMID 32099039 DOI: 10.1038/S41598-020-60961-Z  0.573
2020 Chan CY, Kwok CK. Specific Binding of a D-RNA G-Quadruplex Structure with an L-RNA Aptamer. Angewandte Chemie (International Ed. in English). PMID 31975549 DOI: 10.1002/Anie.201914955  0.598
2020 Shao X, Zhang W, Umar MI, Wong HY, Seng Z, Xie Y, Zhang Y, Yang L, Kwok CK, Deng X. RNA G-Quadruplex Structures Mediate Gene Regulation in Bacteria. Mbio. 11. PMID 31964733 DOI: 10.1128/Mbio.02926-19  0.589
2019 Lyu K, Chen SB, Chan CY, Tan JH, Kwok CK. Structural analysis and cellular visualization of APP RNA G-quadruplex. Chemical Science. 10: 11095-11102. PMID 32206258 DOI: 10.1039/C9Sc02768H  0.612
2019 Umar MI, Ji D, Chan CY, Kwok CK. G-Quadruplex-Based Fluorescent Turn-On Ligands and Aptamers: From Development to Applications. Molecules (Basel, Switzerland). 24. PMID 31262059 DOI: 10.3390/Molecules24132416  0.465
2019 Yeung PY, Zhao J, Chow EY, Mou X, Hong H, Chen L, Chan TF, Kwok CK. Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing. Scientific Reports. 9: 8091. PMID 31147619 DOI: 10.1038/S41598-019-44541-4  0.624
2019 Zhao J, Qian X, Yeung PY, Zhang QC, Kwok CK. Mapping In Vivo RNA Structures and Interactions. Trends in Biochemical Sciences. PMID 30853244 DOI: 10.1016/J.Tibs.2019.01.012  0.608
2019 Chan CY, Umar MI, Kwok CK. Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures. Chemical Communications (Cambridge, England). PMID 30724299 DOI: 10.1039/C8Cc09929D  0.52
2018 Qian X, Zhao J, Yeung PY, Zhang QC, Kwok CK. Revealing lncRNA Structures and Interactions by Sequencing-Based Approaches. Trends in Biochemical Sciences. PMID 30459069 DOI: 10.1016/J.Tibs.2018.09.012  0.666
2018 Chan KL, Peng B, Umar MI, Chan CY, Sahakyan AB, Le MTN, Kwok CK. Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs. Chemical Communications (Cambridge, England). PMID 30204160 DOI: 10.1039/C8Cc04635B  0.689
2018 Ziv O, Gabryelska MM, Lun ATL, Gebert LFR, Sheu-Gruttadauria J, Meredith LW, Liu ZY, Kwok CK, Qin CF, MacRae IJ, Goodfellow I, Marioni JC, Kudla G, Miska EA. COMRADES determines in vivo RNA structures and interactions. Nature Methods. PMID 30202058 DOI: 10.1038/S41592-018-0121-0  0.67
2018 Kwok CK, Marsico G, Balasubramanian S. Detecting RNA G-Quadruplexes (rG4s) in the Transcriptome. Cold Spring Harbor Perspectives in Biology. 10. PMID 29967010 DOI: 10.1101/Cshperspect.A032284  0.762
2018 Ding Y, Kwok CK. Emergence of vascular plants. Nature Plants. PMID 29808025 DOI: 10.1038/S41477-018-0159-0  0.725
2017 Kwok CK, Merrick CJ. G-Quadruplexes: Prediction, Characterization, and Biological Application. Trends in Biotechnology. PMID 28755976 DOI: 10.1016/J.Tibtech.2017.06.012  0.436
2016 Kwok CK. Dawn of the in vivo RNA structurome and interactome. Biochemical Society Transactions. 44: 1395-1410. PMID 27911722 DOI: 10.1042/Bst20160075  0.694
2016 Norris M, Cheema J, Kwok CK, Hartley M, Morris RJ, Aviran S, Ding Y. FoldAtlas: a repository for genome-wide RNA structure probing data. Bioinformatics (Oxford, England). PMID 27663500 DOI: 10.1093/Bioinformatics/Btw611  0.813
2016 Kwok CK, Marsico G, Sahakyan AB, Chambers VS, Balasubramanian S. rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome. Nature Methods. PMID 27571552 DOI: 10.1038/Nmeth.3965  0.851
2016 Kwok CK, Sahakyan AB, Balasubramanian S. Structural Analysis using SHALiPE to Reveal RNA G-Quadruplex Formation in Human Precursor MicroRNA. Angewandte Chemie (International Ed. in English). PMID 27355429 DOI: 10.1002/Anie.201603562  0.834
2016 Sherlock ME, Rumble CA, Kwok CK, Breffke J, Maroncelli M, Bevilacqua PC. Steady-State and Time-Resolved Studies into the Origin of the Intrinsic Fluorescence of G-Quadruplexes. The Journal of Physical Chemistry. B. PMID 27267433 DOI: 10.1021/Acs.Jpcb.6B03790  0.623
2016 Kwok CK, Marsico G, Sahakyan AB, Chambers VS, Balasubramanian S. Transcriptome-wide profiling of RNA G-quadruplex structures using rG4-seq Protocol Exchange. DOI: 10.1038/Protex.2016.060  0.844
2015 Crenshaw E, Leung BP, Kwok CK, Sharoni M, Olson K, Sebastian NP, Ansaloni S, Schweitzer-Stenner R, Akins MR, Bevilacqua PC, Saunders AJ. Amyloid Precursor Protein Translation Is Regulated by a 3'UTR Guanine Quadruplex. Plos One. 10: e0143160. PMID 26618502 DOI: 10.1371/Journal.Pone.0143160  0.671
2015 Ding Y, Kwok CK, Tang Y, Bevilacqua PC, Assmann SM. Genome-wide profiling of in vivo RNA structure at single-nucleotide resolution using structure-seq. Nature Protocols. 10: 1050-66. PMID 26086407 DOI: 10.1038/Nprot.2015.064  0.843
2015 Kwok CK, Balasubramanian S. Targeted Detection of G-Quadruplexes in Cellular RNAs. Angewandte Chemie (International Ed. in English). 54: 6751-4. PMID 25907625 DOI: 10.1002/Anie.201500891  0.737
2015 Tang Y, Bouvier E, Kwok CK, Ding Y, Nekrutenko A, Bevilacqua PC, Assmann SM. StructureFold: genome-wide RNA secondary structure mapping and reconstruction in vivo. Bioinformatics (Oxford, England). PMID 25886980 DOI: 10.1093/Bioinformatics/Btv213  0.843
2015 Kwok CK, Tang Y, Assmann SM, Bevilacqua PC. The RNA structurome: transcriptome-wide structure probing with next-generation sequencing. Trends in Biochemical Sciences. 40: 221-32. PMID 25797096 DOI: 10.1016/J.Tibs.2015.02.005  0.796
2015 Kwok CK, Ding Y, Shahid S, Assmann SM, Bevilacqua PC. A stable RNA G-quadruplex within the 5'-UTR of Arabidopsis thaliana ATR mRNA inhibits translation. The Biochemical Journal. 467: 91-102. PMID 25793418 DOI: 10.1042/Bj20141063  0.819
2015 Lam EKY, Chui APY, Kwok CK, Ip AHP, Chan SW, Leung HN, Yeung LC, Ang PO. High levels of inorganic nutrients affect fertilization kinetics, early development and settlement of the scleractinian coral Platygyra acuta Coral Reefs. DOI: 10.1007/S00338-015-1317-8  0.414
2014 Ding Y, Tang Y, Kwok CK, Zhang Y, Bevilacqua PC, Assmann SM. In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features. Nature. 505: 696-700. PMID 24270811 DOI: 10.1038/Nature12756  0.836
2013 Kwok CK, Ding Y, Tang Y, Assmann SM, Bevilacqua PC. Determination of in vivo RNA structure in low-abundance transcripts. Nature Communications. 4: 2971. PMID 24336128 DOI: 10.1038/Ncomms3971  0.841
2013 Kwok CK, Sherlock ME, Bevilacqua PC. Effect of loop sequence and loop length on the intrinsic fluorescence of G-quadruplexes. Biochemistry. 52: 3019-21. PMID 23621657 DOI: 10.1021/Bi400139E  0.574
2013 Kwok CK, Ding Y, Sherlock ME, Assmann SM, Bevilacqua PC. A hybridization-based approach for quantitative and low-bias single-stranded DNA ligation. Analytical Biochemistry. 435: 181-6. PMID 23399535 DOI: 10.1016/J.Ab.2013.01.008  0.713
2013 Kwok CK, Sherlock ME, Bevilacqua PC. Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes. Angewandte Chemie (International Ed. in English). 52: 683-6. PMID 23166020 DOI: 10.1002/Anie.201206475  0.761
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