Year |
Citation |
Score |
2024 |
Patel R, Cardona CL, Angeles E, Singh G, Ashok A, Teich AF, Sproul AA. Reduced SH3RF3 may protect against Alzheimer's disease by lowering microglial pro-inflammatory responses via modulation of JNK and NFkB signaling. Biorxiv : the Preprint Server For Biology. PMID 38979369 DOI: 10.1101/2024.06.23.600281 |
0.36 |
|
2024 |
Qu W, Lam M, McInvale JJ, Mares JA, Kwon S, Humala N, Mahajan A, Nguyen T, Jakubiak KA, Mun JY, Tedesco TG, Al-Dalahmah O, Hussaini SA, Sproul AA, Siegelin MD, et al. Xenografted human iPSC-derived neurons with the familial Alzheimer's disease APP mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator. Acta Neuropathologica. 147: 107. PMID 38918213 DOI: 10.1007/s00401-024-02755-5 |
0.454 |
|
2024 |
Al-Dalahmah O, Lam M, McInvale JJ, Qu W, Nguyen T, Mun JY, Kwon S, Ifediora N, Mahajan A, Humala N, Winters T, Angeles E, Jakubiak KA, Kühn R, Kim YA, ... ... Sproul AA, et al. Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons. Cell Stem Cell. PMID 38626772 DOI: 10.1016/j.stem.2024.03.013 |
0.335 |
|
2023 |
Bartosch AMW, Youth EHH, Hansen S, Wu Y, Buchanan HM, Kaufman ME, Xiao H, Koo SY, Ashok A, Sivakumar S, Soni RK, Dumitrescu LC, Lam TG, Ropri AS, Lee AJ, ... ... Sproul AA, et al. ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 38050142 DOI: 10.1523/JNEUROSCI.2324-22.2023 |
0.715 |
|
2023 |
Bartosch AMW, Youth EHH, Hansen S, Kaufman ME, Xiao H, Koo SY, Ashok A, Sivakumar S, Soni RK, Dumitrescu LC, Lam TG, Ropri AS, Lee AJ, Klein HU, Vardarajan BN, ... ... Sproul AA, et al. ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease. Biorxiv : the Preprint Server For Biology. PMID 36993746 DOI: 10.1101/2023.03.21.533654 |
0.719 |
|
2022 |
Bosc E, Anastasie J, Soualmia F, Coric P, Kim JY, Wang LQ, Lacin G, Zhao K, Patel R, Duplus E, Tixador P, Sproul AA, Brugg B, Reboud-Ravaux M, Troy CM, et al. Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics. Cell Death & Disease. 13: 959. PMID 36379916 DOI: 10.1038/s41419-022-05396-2 |
0.353 |
|
2022 |
Kim YA, Siddiqui T, Blaze J, Cosacak MI, Winters T, Kumar A, Tein E, Sproul AA, Teich AF, Bartolini F, Akbarian S, Kizil C, Hargus G, Santa-Maria I. RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation. Acta Neuropathologica. PMID 36357715 DOI: 10.1007/s00401-022-02511-7 |
0.393 |
|
2022 |
Martínez-Hernández J, Parato J, Sharma A, Soleilhac JM, Qu X, Tein E, Sproul A, Andrieux A, Goldberg Y, Moutin MJ, Bartolini F, Peris L. Crosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer's disease. Frontiers in Cell and Developmental Biology. 10: 926914. PMID 36092705 DOI: 10.3389/fcell.2022.926914 |
0.34 |
|
2022 |
Lee A, Kondapalli C, Virga DM, Lewis TL, Koo SY, Ashok A, Mairet-Coello G, Herzig S, Foretz M, Viollet B, Shaw R, Sproul A, Polleux F. Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy. Nature Communications. 13: 4444. PMID 35915085 DOI: 10.1038/s41467-022-32130-5 |
0.706 |
|
2022 |
Peris L, Parato J, Qu X, Soleilhac JM, Lanté F, Kumar A, Pero ME, Martínez-Hernández J, Corrao C, Falivelli G, Payet F, Gory-Fauré S, Bosc C, Blanca Ramírez M, Sproul A, et al. Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer's disease. Brain : a Journal of Neurology. PMID 35148384 DOI: 10.1093/brain/awab436 |
0.342 |
|
2020 |
Montesinos J, Pera M, Larrea D, Guardia-Laguarta C, Agrawal RR, Velasco KR, Yun TD, Stavrovskaya IG, Xu Y, Koo SY, Snead AM, Sproul AA, Area-Gomez E. The Alzheimer's disease-associated C99 fragment of APP regulates cellular cholesterol trafficking. The Embo Journal. e103791. PMID 32865299 DOI: 10.15252/Embj.2019103791 |
0.689 |
|
2019 |
Martín-Maestro P, Sproul A, Martinez H, Paquet D, Gerges M, Noggle S, Starkov AA. Autophagy Induction by Bexarotene Promotes Mitophagy in Presenilin 1 Familial Alzheimer's Disease iPSC-Derived Neural Stem Cells. Molecular Neurobiology. PMID 31203573 DOI: 10.1007/S12035-019-01665-Y |
0.453 |
|
2019 |
Sun J, Carlson-Stevermer J, Das U, Shen M, Delenclos M, Snead AM, Koo SY, Wang L, Qiao D, Loi J, Petersen AJ, Stockton M, Bhattacharyya A, Jones MV, Zhao X, ... ... Sproul AA, et al. CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage. Nature Communications. 10: 53. PMID 30604771 DOI: 10.1038/S41467-018-07971-8 |
0.706 |
|
2018 |
Chung KM, Hernández N, Sproul A, Yu WH. Alzheimer's disease and the autophagic-lysosomal system. Neuroscience Letters. PMID 29758300 DOI: 10.1016/J.Neulet.2018.05.017 |
0.446 |
|
2017 |
Ortiz-Virumbrales M, Moreno CL, Kruglikov I, Marazuela P, Sproul A, Jacob S, Zimmer M, Paull D, Zhang B, Schadt EE, Ehrlich ME, Tanzi RE, Arancio O, Noggle S, Gandy S. CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 (N141I) neurons. Acta Neuropathologica Communications. 5: 77. PMID 29078805 DOI: 10.1186/S40478-017-0475-Z |
0.373 |
|
2016 |
Ortiz-Virumbrales M, Moreno C, Sproul A, Jacob S, Zimmer M, Kruglikov I, Paull D, Marazuela P, Ehrlich ME, Tanzi R, Schadt E, Noggle S, Gandy S. P4-278: Characterization of Basal Forebrain Cholinergic Neurons From Induced Pluripotent Stem Cells Harboring Familial Alzheimer’S MUTATION PSEN2
N141I Alzheimer's & Dementia. 12: P1139-P1139. DOI: 10.1016/J.Jalz.2016.07.020 |
0.323 |
|
2016 |
Kwart D, Paquet D, Chen A, Sproul A, Jacob S, Teo S, Olsen KM, Gregg A, Noggle S, Tessier-Lavigne M. S3-02-02: A Novel Human IPSC-Based Model of Alzheimer's Disease Generated by Knock-in of Early-Onset AD Mutations Displays Disease-Relevant, Zygosity-Dependent Phenotypes Alzheimer's & Dementia. 12: P267-P268. DOI: 10.1016/J.Jalz.2016.06.484 |
0.372 |
|
2014 |
Sproul A, Jacob S, Paquet D, Ortiz-Virumbrales M, Campos B, Gandy S, Tessier-Lavigne M, Noggle S. P3-042: USING FAMILIAL ALZHEIMER'S DISEASE AND ISOGENIC CONTROL IPSC-DERIVED BASAL FOREBRAIN NEURONS TO MODEL AD Alzheimer's & Dementia. 10: P643-P644. DOI: 10.1016/J.Jalz.2014.05.1129 |
0.315 |
|
2012 |
Wilhelm M, Kukekov NV, Schmit TL, Biagas KV, Sproul AA, Gire S, Maes ME, Xu Z, Greene LA. Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. The Journal of Biological Chemistry. 287: 2247-56. PMID 22128169 DOI: 10.1074/Jbc.M111.269431 |
0.664 |
|
2009 |
Sproul AA, Xu Z, Wilhelm M, Gire S, Greene LA. Cbl negatively regulates JNK activation and cell death. Cell Research. 19: 950-61. PMID 19546888 DOI: 10.1038/Cr.2009.74 |
0.676 |
|
2007 |
Biswas SC, Shi Y, Sproul A, Greene LA. Pro-apoptotic Bim induction in response to nerve growth factor deprivation requires simultaneous activation of three different death signaling pathways. The Journal of Biological Chemistry. 282: 29368-74. PMID 17702754 DOI: 10.1074/Jbc.M702634200 |
0.581 |
|
2006 |
Xu Z, Sproul A, Wang W, Kukekov N, Greene LA. Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis. The Journal of Biological Chemistry. 281: 303-12. PMID 16230351 DOI: 10.1074/Jbc.M509060200 |
0.652 |
|
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