Alexandre Specht - Publications

Affiliations: 
Universite de Strasbourg (France) 

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Nakad EA, Chaud J, Morville C, Bolze F, Specht A. Monitoring of uncaging processes by designing photolytical reactions. Photochemical and Photobiological Sciences. 19: 1122-1133. PMID 32756690 DOI: 10.1039/D0Pp00169D  0.329
2018 Specht A, Goegan B, Terzi F, Bolze F, Cambridge S. Synthesis and Characterization of photoactivatable doxycycline analogues bearing two-photon sensitive photoremovable groups suitable for light induced gene expression. Chembiochem : a European Journal of Chemical Biology. PMID 29341417 DOI: 10.1002/Cbic.201700628  0.344
2017 Harkat M, Peverini L, Cerdan AH, Dunning K, Beudez J, Martz A, Calimet N, Specht A, Cecchini M, Chataigneau T, Grutter T. On the permeation of large organic cations through the pore of ATP-gated P2X receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28442564 DOI: 10.1073/Pnas.1701379114  0.667
2016 Fichte MA, Weyel XM, Junek S, Schäfer F, Herbivo C, Goeldner M, Specht A, Wachtveitl J, Heckel A. Three-Dimensional Control of DNA Hybridization by Orthogonal Two-Color Two-Photon Uncaging. Angewandte Chemie (International Ed. in English). PMID 27294300 DOI: 10.1002/Anie.201603281  0.564
2016 Habermacher C, Martz A, Calimet N, Lemoine D, Peverini L, Specht A, Cecchini M, Grutter T. Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel. Elife. 5. PMID 26808983 DOI: 10.7554/Elife.11050  0.671
2016 Piant S, Bolze F, Specht A. Two-photon uncaging, from neuroscience to materials Optical Materials Express. 6: 1679-1691. DOI: 10.1364/Ome.6.001679  0.344
2016 Piant S, Specht A, Zemelman B, Losonczy A, Bolze F. Two-photon sensitive photolabile protecting groups: From molecular engineering to nanostructuration Molecular Crystals and Liquid Crystals. 627: 56-65. DOI: 10.1080/15421406.2015.1137119  0.323
2015 Habermacher C, Martz A, Calimet N, Lemoine D, Peverini L, Specht A, Cecchini M, Grutter T. Author response: Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel Elife. DOI: 10.7554/Elife.11050.029  0.637
2014 García-Fernández L, Specht A, Del Campo A. A Polyurethane-Based Positive Photoresist. Macromolecular Rapid Communications. PMID 25220363 DOI: 10.1002/Marc.201400331  0.301
2014 Piant S, Gug S, Warter D, Donato L, Specht A, Goeldner M, Nicoud J, Zemelman B, Losonzy A, Bolze F. Two-photon sensitive photolabile protecting groups: From molecular engineering to nanostructuration Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2014.Bt3A.33  0.57
2013 Lemoine D, Habermacher C, Martz A, Méry PF, Bouquier N, Diverchy F, Taly A, Rassendren F, Specht A, Grutter T. Optical control of an ion channel gate. Proceedings of the National Academy of Sciences of the United States of America. 110: 20813-8. PMID 24297890 DOI: 10.1073/Pnas.1318715110  0.67
2013 Herbivo C, Omran Z, Revol J, Javot H, Specht A. Synthesis and characterization of cell-permeable caged phosphates that can be photolyzed by visible light or 800 nm two-photon photolysis. Chembiochem : a European Journal of Chemical Biology. 14: 2277-83. PMID 24123793 DOI: 10.1002/Cbic.201300425  0.358
2013 Specht A, Bolze F, Nicoud JF, Goeldner M. Characterization of one- and two-photon photochemical uncaging efficiency. Methods in Molecular Biology (Clifton, N.J.). 995: 79-87. PMID 23494373 DOI: 10.1007/978-1-62703-345-9_6  0.586
2013 Herbivo C, Omran Z, Revol J, Javot H, Specht A. Cover Picture: Synthesis and Characterization of Cell-Permeable Caged Phosphates that Can Be Photolyzed by Visible Light or 800 nm Two-Photon Photolysis (ChemBioChem 17/2013) Chembiochem. 14: 2221-2221. DOI: 10.1002/Cbic.201390062  0.3
2012 Jiang R, Taly A, Lemoine D, Martz A, Specht A, Grutter T. Intermediate closed channel state(s) precede(s) activation in the ATP-gated P2X2 receptor. Channels (Austin, Tex.). 6: 398-402. PMID 22992569 DOI: 10.4161/Chan.21520  0.659
2012 Lemoine D, Jiang R, Taly A, Chataigneau T, Specht A, Grutter T. Ligand-gated ion channels: new insights into neurological disorders and ligand recognition. Chemical Reviews. 112: 6285-318. PMID 22988962 DOI: 10.1021/Cr3000829  0.643
2012 Specht A, Bolze F, Donato L, Herbivo C, Charon S, Warther D, Gug S, Nicoud JF, Goeldner M. The donor-acceptor biphenyl platform: a versatile chromophore for the engineering of highly efficient two-photon sensitive photoremovable protecting groups. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 11: 578-86. PMID 22322902 DOI: 10.1039/C2Pp05360H  0.586
2012 Donato L, Mourot A, Davenport CM, Herbivo C, Warther D, Léonard J, Bolze F, Nicoud JF, Kramer RH, Goeldner M, Specht A. Water-soluble, donor-acceptor biphenyl derivatives in the 2-(o-nitrophenyl)propyl series: highly efficient two-photon uncaging of the neurotransmitter γ-aminobutyric acid at λ = 800 nm. Angewandte Chemie (International Ed. in English). 51: 1840-3. PMID 22238209 DOI: 10.1002/Anie.201106559  0.712
2012 Bolze F, Nicoud JF, Bourgogne C, Gug S, Sun XH, Goeldner M, Specht A, Donato L, Warther D, Turi GF, Losonczy A. Two-photon uncaging: The chemist point of view Optical Materials. 34: 1664-1669. DOI: 10.1016/J.Optmat.2012.03.007  0.586
2011 Jiang R, Lemoine D, Martz A, Taly A, Gonin S, Prado de Carvalho L, Specht A, Grutter T. Agonist trapped in ATP-binding sites of the P2X2 receptor. Proceedings of the National Academy of Sciences of the United States of America. 108: 9066-71. PMID 21576497 DOI: 10.1073/Pnas.1102170108  0.661
2011 Jiang R, Miyamoto A, Martz A, Specht A, Ishibashi H, Kueny-Stotz M, Chassaing S, Brouillard R, de Carvalho LP, Goeldner M, Nabekura J, Nielsen M, Grutter T. Retrochalcone derivatives are positive allosteric modulators at synaptic and extrasynaptic GABA(A) receptors in vitro. British Journal of Pharmacology. 162: 1326-39. PMID 21133889 DOI: 10.1111/J.1476-5381.2010.01142.X  0.694
2011 Puliti D, Warther D, Orange C, Specht A, Goeldner M. Small photoactivatable molecules for controlled fluorescence activation in living cells. Bioorganic & Medicinal Chemistry. 19: 1023-9. PMID 20675143 DOI: 10.1016/J.Bmc.2010.07.011  0.554
2011 Bolze F, Nicoud JF, Gug S, Charon S, Specht A, Goeldner M, Warther D, Sun XH, Kessler P, Lutz Y, Vonesch JL, Losonczy A. Two-photon excitation in life sciences: Neurotransmitter and fluorescence uncaging Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7903. DOI: 10.1117/12.873742  0.579
2010 Warther D, Gug S, Specht A, Bolze F, Nicoud JF, Mourot A, Goeldner M. Two-photon uncaging: New prospects in neuroscience and cellular biology. Bioorganic & Medicinal Chemistry. 18: 7753-8. PMID 20554207 DOI: 10.1016/J.Bmc.2010.04.084  0.715
2010 Warther D, Bolze F, Léonard J, Gug S, Specht A, Puliti D, Sun XH, Kessler P, Lutz Y, Vonesch JL, Winsor B, Nicoud JF, Goeldner M. Live-cell one- and two-photon uncaging of a far-red emitting acridinone fluorophore. Journal of the American Chemical Society. 132: 2585-90. PMID 20141131 DOI: 10.1021/Ja9074562  0.576
2010 Bolze F, Niehl A, Heinlein M, Mjdasiri N, Rehspringer JL, Schaeffer N, Didier P, Arntz Y, Mély Y, Gug S, Specht A, Goeldner M, Nicoud JF. Two-photon excitation in life sciences: From observation to action Nonlinear Optics Quantum Optics. 40: 253-265.  0.487
2009 Specht A, Bolze F, Omran Z, Nicoud JF, Goeldner M. Photochemical tools to study dynamic biological processes. Hfsp Journal. 3: 255-64. PMID 20119482 DOI: 10.2976/1.3132954  0.564
2009 Omran Z, Specht A. Short-length dimethoxynitrophenyl photo-cleavable crosslinkers, synthesis and photolysis Journal of Photochemistry and Photobiology a: Chemistry. 208: 125-130. DOI: 10.1016/J.Jphotochem.2009.09.005  0.307
2009 Specht A, Loudwig S, Peng L, Goeldner M. Complexing photolabile cholinergic ligands with synthetic and biological receptors: A dynamic survey Journal of Inclusion Phenomena and Macrocyclic Chemistry. 65: 157-163. DOI: 10.1007/S10847-009-9603-0  0.728
2008 Gug S, Bolze F, Specht A, Bourgogne C, Goeldner M, Nicoud JF. Molecular engineering of photoremovable protecting groups for two-photon uncaging. Angewandte Chemie (International Ed. in English). 47: 9525-9. PMID 18972480 DOI: 10.1002/Anie.200803964  0.564
2008 Guerlet G, Taly A, Prado de Carvalho L, Martz A, Jiang R, Specht A, Le Novère N, Grutter T. Comparative models of P2X2 receptor support inter-subunit ATP-binding sites. Biochemical and Biophysical Research Communications. 375: 405-9. PMID 18718445 DOI: 10.1016/J.Bbrc.2008.08.030  0.661
2008 Gug S, Charon S, Specht A, Alarcon K, Ogden D, Zietz B, Léonard J, Haacke S, Bolze F, Nicoud JF, Goeldner M. Photolabile glutamate protecting group with high one- and two-photon uncaging efficiencies. Chembiochem : a European Journal of Chemical Biology. 9: 1303-7. PMID 18386275 DOI: 10.1002/Cbic.200700651  0.592
2008 Petersen S, Alonso JM, Specht A, Duodu P, Goeldner M, del Campo A. Phototriggering of cell adhesion by caged cyclic RGD peptides. Angewandte Chemie (International Ed. in English). 47: 3192-5. PMID 18348119 DOI: 10.1002/Anie.200704857  0.496
2008 Orange C, Specht A, Puliti D, Sakr E, Furuta T, Winsor B, Goeldner M. Synthesis and photochemical properties of a light-activated fluorophore to label His-tagged proteins. Chemical Communications (Cambridge, England). 1217-9. PMID 18309422 DOI: 10.1039/B716486F  0.565
2007 Colletier JP, Royant A, Specht A, Sanson B, Nachon F, Masson P, Zaccai G, Sussman JL, Goeldner M, Silman I, Bourgeois D, Weik M. Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography. Acta Crystallographica. Section D, Biological Crystallography. 63: 1115-28. PMID 18007027 DOI: 10.1107/S0907444907044472  0.552
2006 Specht A, Thomann JS, Alarcon K, Wittayanan W, Ogden D, Furuta T, Kurakawa Y, Goeldner M. New photoremovable protecting groups for carboxylic acids with high photolytic efficiencies at near-UV irradiation. Application to the photocontrolled release of L-glutamate. Chembiochem : a European Journal of Chemical Biology. 7: 1690-5. PMID 16991166 DOI: 10.1002/Cbic.200600111  0.565
2005 Specht A, Ziarelli F, Bernard P, Goeldner M, Peng L. para-sulfonated calixarenes used as synthetic receptors for complexing photolabile cholinergic ligand Helvetica Chimica Acta. 88: 2641-2653. DOI: 10.1002/Hlca.200590205  0.584
2004 Specht A, Goeldner M. 1-(o-Nitrophenyl)-2,2,2-trifluoroethyl ether derivatives as stable and efficient photoremovable alcohol-protecting groups. Angewandte Chemie (International Ed. in English). 43: 2008-12. PMID 15065287 DOI: 10.1002/Anie.200353247  0.54
2002 Specht A, Bernard P, Goeldner M, Peng L. Mutually induced formation of host-guest complexes between p-sulfonated calix[8]arene and photolabile cholinergic ligands. Angewandte Chemie (International Ed. in English). 41: 4706-8. PMID 12481333 DOI: 10.1002/Anie.200290023  0.58
2002 Specht A, Loudwig S, Peng L, Goeldner M. p-Hydroxyphenacyl bromide as photoremoveable thiol label: A potential phototrigger for thiol-containing biomolecules Tetrahedron Letters. 43: 8947-8950. DOI: 10.1016/S0040-4039(02)02194-9  0.722
2002 Loudwig S, Specht A, Goeldner M. Caged compounds, the photolabile precursors of bioactive molecules. Developments and prospects | Les composés « cagés » ou les précurseurs photochimiques de molécules biologiquement actives. Mise au point et perspectives Actualite Chimique. 7-12.  0.708
2001 Specht A, Ursby T, Weik M, Peng L, Kroon J, Bourgeois D, Goeldner M. Cryophotolysis of ortho-nitrobenzyl derivatives of enzyme ligands for the potential kinetic crystallography of macromolecules. Chembiochem : a European Journal of Chemical Biology. 2: 845-8. PMID 11948871 DOI: 10.1002/1439-7633(20011105)2:11<845::Aid-Cbic845>3.0.Co;2-C  0.563
1999 Specht A, Goeldner M, Wirz J, Peng L. Characterization of caged cholinergic ligands; sulfonated calix[4]arene inclusion complexes Synlett. 981-983. DOI: 10.1055/S-1999-3108  0.546
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