John T. Isaac - Publications

Affiliations: 
National Institutes of Health, Bethesda, MD 
Area:
Synaptic plasticity; synaptic function; hippocampus; barrel cortex; AMPAR; kianate receptor

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Year Citation  Score
2020 Petrus E, Dembling S, Usdin T, Isaac JT, Koretsky AP. Circuit Specific Plasticity of Callosal Inputs Underlies Cortical Takeover. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32913109 DOI: 10.1523/Jneurosci.1056-20.2020  0.372
2017 Jackson JS, Witton J, Johnson JD, Ahmed Z, Ward M, Randall AD, Hutton ML, Isaac JT, O'Neill MJ, Ashby MC. Altered Synapse Stability in the Early Stages of Tauopathy. Cell Reports. 18: 3063-3068. PMID 28355559 DOI: 10.1016/J.Celrep.2017.03.013  0.838
2017 Jackson J, Tamagnini F, Johnson J, Stephen T, Ahmed Z, Oliver-Evans A, Meftah S, Hutton ML, Isaac J, Randall A, Ashby M, O'Neill MJ. In Vivo Two-Photon Imaging Of The Effects Of Tauopathy And Amyloidopathy On Synapses Alzheimers & Dementia. 13: 1002. DOI: 10.1016/J.Jalz.2017.06.1390  0.791
2016 Kato AS, Burris KD, Gardinier KM, Gernert DL, Porter WJ, Reel J, Ding C, Tu Y, Schober DA, Lee MR, Heinz BA, Fitch TE, Gleason SD, Catlow JT, Yu H, ... ... Isaac JT, et al. Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism. Nature Medicine. PMID 27820603 DOI: 10.1038/Nm.4221  0.821
2015 Dennis SH, Pasqui F, Colvin EM, Sanger H, Mogg AJ, Felder CC, Broad LM, Fitzjohn SM, Isaac JT, Mellor JR. Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus. Cerebral Cortex (New York, N.Y. : 1991). PMID 26472558 DOI: 10.1093/Cercor/Bhv227  0.863
2015 Crocker-Buque A, Brown SM, Kind PC, Isaac JT, Daw MI. Experience-Dependent, Layer-Specific Development of Divergent Thalamocortical Connectivity. Cerebral Cortex (New York, N.Y. : 1991). 25: 2255-66. PMID 24610243 DOI: 10.1093/Cercor/Bhu031  0.768
2014 Dage JL, Colvin EM, Fouillet A, Langron E, Roell WC, Li J, Mathur SX, Mogg AJ, Schmitt MG, Felder CC, Merchant KM, Isaac J, Broad LM, Sher E, Ursu D. Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons. Psychopharmacology. 231: 1105-24. PMID 24429870 DOI: 10.1007/S00213-013-3384-2  0.384
2014 Morita D, Rah JC, Isaac JT. Incorporation of inwardly rectifying AMPA receptors at silent synapses during hippocampal long-term potentiation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130156. PMID 24298157 DOI: 10.1098/rstb.2013.0156  0.795
2014 Jackson J, Johnson J, Ahmed Z, Ward M, Hutton M, Ashby M, Isaac J, O'Neill M. In Vivo Two-Photon Imaging Of Progressive Synapse Loss And Altered Spine Dynamics In The Rtg4510 Tauopathy Model Alzheimers & Dementia. 10: 29. DOI: 10.1016/J.Jalz.2014.05.054  0.76
2013 Rah JC, Bas E, Colonell J, Mishchenko Y, Karsh B, Fetter RD, Myers EW, Chklovskii DB, Svoboda K, Harris TD, Isaac JT. Thalamocortical input onto layer 5 pyramidal neurons measured using quantitative large-scale array tomography. Frontiers in Neural Circuits. 7: 177. PMID 24273494 DOI: 10.3389/Fncir.2013.00177  0.716
2013 Crabtree JW, Lodge D, Bashir ZI, Isaac JT. GABAA , NMDA and mGlu2 receptors tonically regulate inhibition and excitation in the thalamic reticular nucleus. The European Journal of Neuroscience. 37: 850-9. PMID 23294136 DOI: 10.1111/ejn.12098  0.742
2012 Kato AS, Knierman MD, Siuda ER, Isaac JT, Nisenbaum ES, Bredt DS. Glutamate receptor δ2 associates with metabotropic glutamate receptor 1 (mGluR1), protein kinase Cγ, and canonical transient receptor potential 3 and regulates mGluR1-mediated synaptic transmission in cerebellar Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15296-308. PMID 23115168 DOI: 10.1523/Jneurosci.0705-12.2012  0.508
2012 Yu X, Chung S, Chen DY, Wang S, Dodd SJ, Walters JR, Isaac JT, Koretsky AP. Thalamocortical inputs show post-critical-period plasticity. Neuron. 74: 731-42. PMID 22632730 DOI: 10.1016/J.Neuron.2012.04.024  0.69
2011 Ashby MC, Isaac JT. Maturation of a recurrent excitatory neocortical circuit by experience-dependent unsilencing of newly formed dendritic spines. Neuron. 70: 510-21. PMID 21555076 DOI: 10.1016/J.Neuron.2011.02.057  0.734
2011 Matta JA, Ashby MC, Sanz-Clemente A, Roche KW, Isaac JT. mGluR5 and NMDA receptors drive the experience- and activity-dependent NMDA receptor NR2B to NR2A subunit switch. Neuron. 70: 339-51. PMID 21521618 DOI: 10.1016/J.Neuron.2011.02.045  0.836
2011 Bortolotto ZA, Amici M, Anderson WW, Isaac JT, Collingridge GL. Synaptic plasticity in the hippocampal slice preparation. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 6.13. PMID 21207366 DOI: 10.1002/0471142301.ns0613s54  0.814
2011 Jouhanneau JS, Ball SM, Molnár E, Isaac JT. Mechanisms of bi-directional modulation of thalamocortical transmission in barrel cortex by presynaptic kainate receptors. Neuropharmacology. 60: 832-41. PMID 21187105 DOI: 10.1016/J.Neuropharm.2010.12.023  0.859
2010 Brown JT, Weatherall KL, Corria LR, Chater TE, Isaac JT, Marrion NV. Vesicular release of glutamate utilizes the proton gradient between the vesicle and synaptic cleft. Frontiers in Synaptic Neuroscience. 2: 15. PMID 21423501 DOI: 10.3389/fnsyn.2010.00015  0.583
2010 Chittajallu R, Isaac JT. Emergence of cortical inhibition by coordinated sensory-driven plasticity at distinct synaptic loci. Nature Neuroscience. 13: 1240-8. PMID 20871602 DOI: 10.1038/nn.2639  0.834
2010 Sanz-Clemente A, Matta JA, Isaac JT, Roche KW. Casein kinase 2 regulates the NR2 subunit composition of synaptic NMDA receptors. Neuron. 67: 984-96. PMID 20869595 DOI: 10.1016/J.Neuron.2010.08.011  0.832
2010 Evers DM, Matta JA, Hoe HS, Zarkowsky D, Lee SH, Isaac JT, Pak DT. Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation. Nature Neuroscience. 13: 1199-207. PMID 20802490 DOI: 10.1038/Nn.2624  0.834
2010 Suh YH, Terashima A, Petralia RS, Wenthold RJ, Isaac JT, Roche KW, Roche PA. A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking. Nature Neuroscience. 13: 338-43. PMID 20118925 DOI: 10.1038/nn.2488  0.655
2010 Nasu-Nishimura Y, Jaffe H, Isaac JT, Roche KW. Differential regulation of kainate receptor trafficking by phosphorylation of distinct sites on GluR6. The Journal of Biological Chemistry. 285: 2847-56. PMID 19920140 DOI: 10.1074/jbc.M109.081141  0.456
2009 Walker CS, Jensen S, Ellison M, Matta JA, Lee WY, Imperial JS, Duclos N, Brockie PJ, Madsen DM, Isaac JT, Olivera B, Maricq AV. A novel Conus snail polypeptide causes excitotoxicity by blocking desensitization of AMPA receptors. Current Biology : Cb. 19: 900-8. PMID 19481459 DOI: 10.1016/J.Cub.2009.05.017  0.786
2009 Isaac JT, Buchanan KA, Muller RU, Mellor JR. Hippocampal place cell firing patterns can induce long-term synaptic plasticity in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6840-50. PMID 19474311 DOI: 10.1523/JNEUROSCI.0731-09.2009  0.498
2009 Lüscher C, Isaac JT. The synapse: center stage for many brain diseases. The Journal of Physiology. 587: 727-9. PMID 19074963 DOI: 10.1113/jphysiol.2008.167742  0.5
2008 Mistry RB, Isaac JT, Crabtree JW. Two differential frequency-dependent mechanisms regulating tonic firing of thalamic reticular neurons. The European Journal of Neuroscience. 27: 2643-56. PMID 18547248 DOI: 10.1111/j.1460-9568.2008.06246.x  0.343
2008 Terashima A, Pelkey KA, Rah JC, Suh YH, Roche KW, Collingridge GL, McBain CJ, Isaac JT. An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity. Neuron. 57: 872-82. PMID 18367088 DOI: 10.1016/j.neuron.2008.01.028  0.88
2007 Daw M, Isaac J. Electrophysiological recordings from neonatal neocortical brain slices Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 6.23. PMID 18428662 DOI: 10.1002/0471142301.Ns0623S38  0.764
2007 Isaac JT, Ashby MC, McBain CJ. The role of the GluR2 subunit in AMPA receptor function and synaptic plasticity. Neuron. 54: 859-71. PMID 17582328 DOI: 10.1016/J.Neuron.2007.06.001  0.851
2007 Daw MI, Ashby MC, Isaac JT. Coordinated developmental recruitment of latent fast spiking interneurons in layer IV barrel cortex. Nature Neuroscience. 10: 453-61. PMID 17351636 DOI: 10.1038/Nn1866  0.808
2007 Peineau S, Taghibiglou C, Bradley C, Wong TP, Liu L, Lu J, Lo E, Wu D, Saule E, Bouschet T, Matthews P, Isaac JT, Bortolotto ZA, Wang YT, Collingridge GL. LTP inhibits LTD in the hippocampus via regulation of GSK3beta. Neuron. 53: 703-17. PMID 17329210 DOI: 10.1016/J.Neuron.2007.01.029  0.829
2007 Daw MI, Scott HL, Isaac JT. Developmental synaptic plasticity at the thalamocortical input to barrel cortex: mechanisms and roles. Molecular and Cellular Neurosciences. 34: 493-502. PMID 17329121 DOI: 10.1016/J.Mcn.2007.01.001  0.847
2007 Scott HL, Braud S, Bannister NJ, Isaac JT. Synaptic strength at the thalamocortical input to layer IV neonatal barrel cortex is regulated by protein kinase C. Neuropharmacology. 52: 185-92. PMID 16890249 DOI: 10.1016/j.neuropharm.2006.06.016  0.825
2006 Bi GQ, Bolshakov V, Bu G, Cahill CM, Chen ZF, Collingridge GL, Cooper RL, Coorssen JR, El-Husseini A, Galhardo V, Gan WB, Gu J, Inoue K, Isaac J, Iwata K, et al. Recent advances in basic neurosciences and brain disease: from synapses to behavior. Molecular Pain. 2: 38. PMID 17196111 DOI: 10.1186/1744-8069-2-38  0.643
2006 Nasu-Nishimura Y, Hurtado D, Braud S, Tang TT, Isaac JT, Roche KW. Identification of an endoplasmic reticulum-retention motif in an intracellular loop of the kainate receptor subunit KA2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7014-21. PMID 16807331 DOI: 10.1523/Jneurosci.0573-06.2006  0.724
2006 Lauri SE, Vesikansa A, SegerstrÃ¥le M, Collingridge GL, Isaac JT, Taira T. Functional maturation of CA1 synapses involves activity-dependent loss of tonic kainate receptor-mediated inhibition of glutamate release. Neuron. 50: 415-29. PMID 16675396 DOI: 10.1016/j.neuron.2006.03.020  0.736
2006 Daw MI, Bannister NV, Isaac JT. Rapid, activity-dependent plasticity in timing precision in neonatal barrel cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4178-87. PMID 16624938 DOI: 10.1523/Jneurosci.0150-06.2006  0.838
2006 Chen BS, Braud S, Badger JD, Isaac JT, Roche KW. Regulation of NR1/NR2C N-methyl-D-aspartate (NMDA) receptors by phosphorylation. The Journal of Biological Chemistry. 281: 16583-90. PMID 16606616 DOI: 10.1074/jbc.M513029200  0.751
2006 Plant K, Pelkey KA, Bortolotto ZA, Morita D, Terashima A, McBain CJ, Collingridge GL, Isaac JT. Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation. Nature Neuroscience. 9: 602-4. PMID 16582904 DOI: 10.1038/nn1678  0.856
2006 Park Y, Jo J, Isaac JT, Cho K. Long-term depression of kainate receptor-mediated synaptic transmission. Neuron. 49: 95-106. PMID 16387642 DOI: 10.1016/j.neuron.2005.11.035  0.459
2005 Palmer CL, Lim W, Hastie PG, Toward M, Korolchuk VI, Burbidge SA, Banting G, Collingridge GL, Isaac JT, Henley JM. Hippocalcin functions as a calcium sensor in hippocampal LTD. Neuron. 47: 487-94. PMID 16102532 DOI: 10.1016/J.Neuron.2005.06.014  0.719
2005 Maingret F, Lauri SE, Taira T, Isaac JT. Profound regulation of neonatal CA1 rat hippocampal GABAergic transmission by functionally distinct kainate receptor populations. The Journal of Physiology. 567: 131-42. PMID 15946969 DOI: 10.1113/jphysiol.2005.089474  0.472
2005 Bannister NJ, Benke TA, Mellor J, Scott H, Gürdal E, Crabtree JW, Isaac JT. Developmental changes in AMPA and kainate receptor-mediated quantal transmission at thalamocortical synapses in the barrel cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5259-71. PMID 15917466 DOI: 10.1523/Jneurosci.0827-05.2005  0.844
2005 Kim CH, Braud S, Isaac JT, Roche KW. Protein kinase C phosphorylation of the metabotropic glutamate receptor mGluR5 on Serine 839 regulates Ca2+ oscillations. The Journal of Biological Chemistry. 280: 25409-15. PMID 15894802 DOI: 10.1074/jbc.M502644200  0.718
2005 Lauri SE, SegerstrÃ¥le M, Vesikansa A, Maingret F, Mulle C, Collingridge GL, Isaac JT, Taira T. Endogenous activation of kainate receptors regulates glutamate release and network activity in the developing hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4473-84. PMID 15872094 DOI: 10.1523/Jneurosci.4050-04.2005  0.754
2005 Lim W, Isaac JT. ATP hydrolysis is required for the rapid regulation of AMPA receptors during basal synaptic transmission and long-term synaptic plasticity. Neuropharmacology. 48: 949-55. PMID 15857621 DOI: 10.1016/j.neuropharm.2005.02.001  0.559
2004 Isaac JT, Mellor J, Hurtado D, Roche KW. Kainate receptor trafficking: physiological roles and molecular mechanisms. Pharmacology & Therapeutics. 104: 163-72. PMID 15556673 DOI: 10.1016/J.Pharmthera.2004.08.006  0.433
2004 Collingridge GL, Isaac JT, Wang YT. Receptor trafficking and synaptic plasticity. Nature Reviews. Neuroscience. 5: 952-62. PMID 15550950 DOI: 10.1038/nrn1556  0.724
2004 Lüthi A, Wikström MA, Palmer MJ, Matthews P, Benke TA, Isaac JT, Collingridge GL. Bi-directional modulation of AMPA receptor unitary conductance by synaptic activity. Bmc Neuroscience. 5: 44. PMID 15538948 DOI: 10.1186/1471-2202-5-44  0.873
2004 Terashima A, Cotton L, Dev KK, Meyer G, Zaman S, Duprat F, Henley JM, Collingridge GL, Isaac JT. Regulation of synaptic strength and AMPA receptor subunit composition by PICK1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5381-90. PMID 15190111 DOI: 10.1523/Jneurosci.4378-03.2004  0.8
2004 Palmer MJ, Isaac JT, Collingridge GL. Multiple, developmentally regulated expression mechanisms of long-term potentiation at CA1 synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4903-11. PMID 15163681 DOI: 10.1523/Jneurosci.0170-04.2004  0.84
2003 Hayes DM, Braud S, Hurtado DE, McCallum J, Standley S, Isaac JT, Roche KW. Trafficking and surface expression of the glutamate receptor subunit, KA2. Biochemical and Biophysical Research Communications. 310: 8-13. PMID 14511640 DOI: 10.1016/j.bbrc.2003.08.115  0.744
2003 Collingridge GL, Isaac JT. Functional roles of protein interactions with AMPA and kainate receptors. Neuroscience Research. 47: 3-15. PMID 12941441 DOI: 10.1016/S0168-0102(03)00160-3  0.777
2003 Isaac JT. Postsynaptic silent synapses: evidence and mechanisms. Neuropharmacology. 45: 450-60. PMID 12907306 DOI: 10.1016/S0028-3908(03)00229-6  0.568
2003 Lauri SE, Bortolotto ZA, Nistico R, Bleakman D, Ornstein PL, Lodge D, Isaac JT, Collingridge GL. A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus. Neuron. 39: 327-41. PMID 12873388 DOI: 10.1016/S0896-6273(03)00369-6  0.834
2003 Duprat F, Daw M, Lim W, Collingridge G, Isaac J. GluR2 protein-protein interactions and the regulation of AMPA receptors during synaptic plasticity Philosophical Transactions of the Royal Society B: Biological Sciences. 358: 715-720. PMID 12740117 DOI: 10.1098/Rstb.2002.1215  0.874
2003 Bortolotto ZA, Lauri S, Isaac JT, Collingridge GL. Kainate receptors and the induction of mossy fibre long-term potentiation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 657-66. PMID 12740111 DOI: 10.1098/rstb.2002.1216  0.83
2003 Hirbec H, Francis JC, Lauri SE, Braithwaite SP, Coussen F, Mulle C, Dev KK, Coutinho V, Meyer G, Isaac JT, Collingridge GL, Henley JM, Couthino V. Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP. Neuron. 37: 625-38. PMID 12597860 DOI: 10.1016/S0896-6273(02)01191-1  0.825
2002 Molnar E, Isaac JT. Developmental and activity dependent regulation of ionotropic glutamate receptors at synapses. Thescientificworldjournal. 2: 27-47. PMID 12806037 DOI: 10.1100/Tsw.2002.74  0.541
2002 Daw MI, Bortolotto ZA, Saulle E, Zaman S, Collingridge GL, Isaac JT. Phosphatidylinositol 3 kinase regulates synapse specificity of hippocampal long-term depression. Nature Neuroscience. 5: 835-6. PMID 12161757 DOI: 10.1038/Nn903  0.845
2002 Kidd FL, Coumis U, Collingridge GL, Crabtree JW, Isaac JT. A presynaptic kainate receptor is involved in regulating the dynamic properties of thalamocortical synapses during development. Neuron. 34: 635-46. PMID 12062046 DOI: 10.1016/S0896-6273(02)00699-2  0.763
2001 Bortolotto ZA, Anderson WW, Isaac JT, Collingridge GL. Synaptic plasticity in the hippocampal slice preparation. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 6.13. PMID 18428512 DOI: 10.1002/0471142301.ns0613s16  0.814
2001 Isaac J. Protein phosphatase 1 and LTD: Synapses are the architects of depression Neuron. 32: 963-966. PMID 11754828 DOI: 10.1016/S0896-6273(01)00545-1  0.496
2001 Benke TA, Lüthi A, Palmer MJ, Wikström MA, Anderson WW, Isaac JT, Collingridge GL. Mathematical modelling of non-stationary fluctuation analysis for studying channel properties of synaptic AMPA receptors. The Journal of Physiology. 537: 407-20. PMID 11731574 DOI: 10.1111/J.1469-7793.2001.00407.X  0.853
2001 Lauri SE, Bortolotto ZA, Bleakman D, Ornstein PL, Lodge D, Isaac JT, Collingridge GL. A critical role of a facilitatory presynaptic kainate receptor in mossy fiber LTP. Neuron. 32: 697-709. PMID 11719209 DOI: 10.1016/S0896-6273(01)00511-6  0.839
2001 Kidd FL, Isaac JT. Kinetics and activation of postsynaptic kainate receptors at thalamocortical synapses: role of glutamate clearance. Journal of Neurophysiology. 86: 1139-48. PMID 11535664  0.539
2001 Hirbec H, Lauri SE, Francis JC, Braithwaite SP, Isaac JT, Collingridge GL, Henley JM. Syntenin interacts with kainate receptors: in vitro and in vivo evidence Biochemical Society Transactions. 29: A88-A88. DOI: 10.1042/Bst029A088C  0.73
2000 Daw MI, Chittajallu R, Bortolotto ZA, Dev KK, Duprat F, Henley JM, Collingridge GL, Isaac JT. PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses. Neuron. 28: 873-86. PMID 11163273 DOI: 10.1016/S0896-6273(00)00160-4  0.812
2000 Kidd FL, Isaac JT. Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex. Neuropharmacology. 39: 725-32. PMID 10699439  0.416
1999 Lüthi A, Chittajallu R, Duprat F, Palmer MJ, Benke TA, Kidd FL, Henley JM, Isaac JT, Collingridge GL. Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction. Neuron. 24: 389-99. PMID 10571232 DOI: 10.1016/S0896-6273(00)80852-1  0.847
1999 Isaac JT, Nicoll RA, Malenka RC. Silent glutamatergic synapses in the mammalian brain. Canadian Journal of Physiology and Pharmacology. 77: 735-7. PMID 10566951 DOI: 10.1139/Y99-075  0.812
1999 Kidd FL, Isaac JT. Developmental and activity-dependent regulation of kainate receptors at thalamocortical synapses. Nature. 400: 569-73. PMID 10448859 DOI: 10.1038/23040  0.549
1999 Hjelmstad GO, Isaac JT, Nicoll RA, Malenka RC. Lack of AMPA receptor desensitization during basal synaptic transmission in the hippocampal slice. Journal of Neurophysiology. 81: 3096-9. PMID 10368425 DOI: 10.1152/Jn.1999.81.6.3096  0.868
1999 Fox K, Henley J, Isaac J. Experience-dependent development of NMDA receptor transmission Nature Neuroscience. 2: 297-299. PMID 10204530 DOI: 10.1038/7203  0.675
1998 Crabtree JW, Collingridge GL, Isaac JT. A new intrathalamic pathway linking modality-related nuclei in the dorsal thalamus. Nature Neuroscience. 1: 389-94. PMID 10196529 DOI: 10.1038/1603  0.586
1998 Isaac JT, Lüthi A, Palmer MJ, Anderson WW, Benke TA, Collingridge GL. An investigation of the expression mechanism of LTP of AMPA receptor-mediated synaptic transmission at hippocampal CA1 synapses using failures analysis and dendritic recordings. Neuropharmacology. 37: 1399-410. PMID 9849675 DOI: 10.1016/S0028-3908(98)00140-3  0.866
1998 Feldman DE, Nicoll RA, Malenka RC, Isaac JT. Long-term depression at thalamocortical synapses in developing rat somatosensory cortex. Neuron. 21: 347-57. PMID 9728916 DOI: 10.1016/S0896-6273(00)80544-9  0.842
1998 Nishimune A, Isaac JT, Molnar E, Noel J, Nash SR, Tagaya M, Collingridge GL, Nakanishi S, Henley JM. NSF binding to GluR2 regulates synaptic transmission. Neuron. 21: 87-97. PMID 9697854 DOI: 10.1016/S0896-6273(00)80517-6  0.812
1998 Benke TA, Lüthi A, Isaac JT, Collingridge GL. Modulation of AMPA receptor unitary conductance by synaptic activity. Nature. 393: 793-7. PMID 9655394 DOI: 10.1038/31709  0.883
1997 Turner DA, Chen Y, Isaac JT, West M, Wheal HV. Excitatory synaptic site heterogeneity during paired pulse plasticity in CA1 pyramidal cells in rat hippocampus in vitro. The Journal of Physiology. 500: 441-61. PMID 9147329 DOI: 10.1113/Jphysiol.1997.Sp022032  0.42
1997 Isaac JT, Crair MC, Nicoll RA, Malenka RC. Silent synapses during development of thalamocortical inputs. Neuron. 18: 269-80. PMID 9052797 DOI: 10.1016/S0896-6273(00)80267-6  0.851
1996 Isaac JT, Oliet SH, Hjelmstad GO, Nicoll RA, Malenka RC. Expression mechanisms of long-term potentiation in the hippocampus. Journal of Physiology, Paris. 90: 299-303. PMID 9089495 DOI: 10.1016/S0928-4257(97)87901-6  0.848
1996 Isaac JT, Hjelmstad GO, Nicoll RA, Malenka RC. Long-term potentiation at single fiber inputs to hippocampal CA1 pyramidal cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 8710-5. PMID 8710936 DOI: 10.1073/pnas.93.16.8710  0.858
1995 Isaac JT, Nicoll RA, Malenka RC. Evidence for silent synapses: implications for the expression of LTP. Neuron. 15: 427-34. PMID 7646894 DOI: 10.1016/0896-6273(95)90046-2  0.827
1993 Isaac JT, Wheal HV. The local anaesthetic QX-314 enables enhanced whole-cell recordings of excitatory synaptic currents in rat hippocampal slices in vitro. Neuroscience Letters. 150: 227-30. PMID 8385755 DOI: 10.1016/0304-3940(93)90542-S  0.694
Low-probability matches (unlikely to be authored by this person)
1993 Isaac J, Chen Y, Turner DA, Wheal HV. Non-equivalent subsets of minimal EPSCs recorded from rat hippocampal CA1 pyramidal cells in vitro Journal of Physiology. 473: 172P.  0.247
2015 L?rincz ML, Gunner D, Bao Y, Connelly WM, Isaac JT, Hughes SW, Crunelli V. A distinct class of slow (~0.2-2 Hz) intrinsically bursting layer 5 pyramidal neurons determines UP/DOWN state dynamics in the neocortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5442-58. PMID 25855163 DOI: 10.1523/Jneurosci.3603-14.2015  0.225
2002 Crabtree JW, Isaac JT. New intrathalamic pathways allowing modality-related and cross-modality switching in the dorsal thalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8754-61. PMID 12351751  0.137
2017 Teles-Grilo Ruivo LM, Baker KL, Conway MW, Kinsley PJ, Gilmour G, Phillips KG, Isaac JT, Lowry JP, Mellor JR. Coordinated Acetylcholine Release in Prefrontal Cortex and Hippocampus Is Associated with Arousal and Reward on Distinct Timescales. Cell Reports. 18: 905-917. PMID 28122241 DOI: 10.1016/j.celrep.2016.12.085  0.134
2010 Chakrabarti L, Best TK, Cramer NP, Carney RS, Isaac JT, Galdzicki Z, Haydar TF. Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome. Nature Neuroscience. 13: 927-34. PMID 20639873 DOI: 10.1038/Nn.2600  0.134
2009 Isaac JT, Feldmeyer D. Mechanisms of neocortical development. The Journal of Physiology. 587: 1871-2. PMID 19406884 DOI: 10.1113/jphysiol.2009.171470  0.122
2014 Mustafa SB, Isaac J, Seidner SR, Dixon PS, Henson BM, DiGeronimo RJ. Mechanical stretch induces lung α-epithelial Na(+) channel expression. Experimental Lung Research. 40: 380-91. PMID 25058750 DOI: 10.3109/01902148.2014.934410  0.1
2019 Halle-Smith JM, Hodson J, Stevens LG, Dasari B, Marudanayagam R, Perera T, Sutcliffe RP, Muiesan P, Isaac J, Mirza DF, Roberts KJ. A comprehensive evaluation of the long-term economic impact of major bile duct injury. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 30862441 DOI: 10.1016/j.hpb.2019.01.018  0.08
2022 Raza SS, Nutu OA, Powell-Brett S, Carvalheiro Boteon A, Hodson J, Abradelo M, Dasari B, Isaac J, Chatzizacharias N, Marudanayagam R, Mirza DF, Roberts JK, Sutcliffe RP. Impact of an enhanced recovery after surgery protocol on short-term outcomes in elderly patients undergoing pancreaticoduodenectomy. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 35643908 DOI: 10.1016/j.hpb.2022.05.002  0.062
2019 Mauricio R, Benn C, Davis J, Dawson G, Dawson LA, Evans A, Fox N, Gallacher J, Hutton M, Isaac J, Jones DNC, Jones L, Lalli G, Libri V, Lovestone S, et al. Tackling gaps in developing life-changing treatments for dementia. Alzheimer's & Dementia (New York, N. Y.). 5: 241-253. PMID 31297438 DOI: 10.1016/J.Trci.2019.05.001  0.06
2012 Isaac JT, Zeadally S. An anonymous secure payment protocol in a payment gateway centric model Procedia Computer Science. 10: 758-765. DOI: 10.1016/J.Procs.2012.06.097  0.057
2020 Halle-Smith JM, Hodson J, Stevens LG, Dasari B, Marudanayagam R, Perera T, Sutcliffe RP, Muiesan P, Isaac J, Mirza DF, Roberts KJ. A comprehensive evaluation of the long-term clinical and economic impact of minor bile duct injury. Surgery. PMID 32183995 DOI: 10.1016/j.surg.2020.01.022  0.054
2007 Isaac JT, Camara JS. An anonymous account-based mobile payment protocol for a restricted connectivity scenario Proceedings - International Workshop On Database and Expert Systems Applications, Dexa. 688-692. DOI: 10.1109/DEXA.2007.132  0.054
2020 Oakley C, Pascoe C, Balthazor D, Bennett D, Gautam N, Isaac J, Isherwood P, Matthews T, Murphy N, Oelofse T, Patel J, Snelson C, Richardson C, Willson J, Wyton F, et al. Assembly Line ICU: what the Long Shops taught us about managing surge capacity for COVID-19. Bmj Open Quality. 9. PMID 33277292 DOI: 10.1136/bmjoq-2020-001117  0.053
2022 Krieckaert C, Hernández-Breijo B, Gehin JE, le Mélédo G, Balsa A, Jani M, Mulleman D, Navarro-Compan V, Wolbink G, Isaac J, van Tubergen A. Therapeutic drug monitoring of biopharmaceuticals in inflammatory rheumatic and musculoskeletal disease: a systematic literature review informing EULAR points to consider. Rmd Open. 8. PMID 35980738 DOI: 10.1136/rmdopen-2022-002216  0.052
2021 Dasari BVM, Wilson M, Pufal K, Kadam P, Hodson J, Roberts KJ, Chatzizacharias N, Marudanayagam R, Gadvi R, Sutcliffe RP, Mirza DF, Muiesan P, Isaac J. Variations between the anatomical and functional distribution, based on 99 technetium -mebrofinate SPECT-CT scan, in patients at risk of post hepatectomy liver failure. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 33975803 DOI: 10.1016/j.hpb.2021.04.014  0.051
2017 Lordan JT, Roberts JK, Hodson J, Isaac J, Muiesan P, Mirza DF, Marudanayagam R, Sutcliffe RP. Case-controlled study comparing peri-operative and cancer-related outcomes after major hepatectomy and parenchymal sparing hepatectomy for metastatic colorectal cancer. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 28495437 DOI: 10.1016/j.hpb.2017.04.007  0.051
2017 Roberts KJ, Prasad P, Steele Y, Marcon F, Faulkner T, Cilliers H, Dasari B, Abradelo M, Marudanayagam R, Sutcliffe RP, Muiesan P, Mirza DF, Isaac J. A reduced time to surgery within a 'fast track' pathway for periampullary malignancy is associated with an increased rate of pancreatoduodenectomy. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 28566239 DOI: 10.1016/j.hpb.2017.04.011  0.048
2014 Isaac JT, Zeadally S. Design, implementation, and performance analysis of a secure payment protocol in a payment gateway centric model Computing. 96: 587-611. DOI: 10.1007/S00607-013-0306-4  0.043
2015 Almond M, Roberts KJ, Hodson J, Sutcliffe R, Marudanayagam R, Isaac J, Muiesan P, Mirza D. Changing indications for a total pancreatectomy: perspectives over a quarter of a century. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. 17: 416-21. PMID 25406456 DOI: 10.1111/hpb.12365  0.041
2017 Laing RW, Mergental H, Yap C, Kirkham A, Whilku M, Barton D, Curbishley S, Boteon YL, Neil DA, Hübscher SG, Perera MTPR, Muiesan P, Isaac J, Roberts KJ, Cilliers H, et al. Viability testing and transplantation of marginal livers (VITTAL) using normothermic machine perfusion: study protocol for an open-label, non-randomised, prospective, single-arm trial. Bmj Open. 7: e017733. PMID 29183928 DOI: 10.1136/bmjopen-2017-017733  0.041
2015 Boutefnouchet T, Gregg R, Tidman J, Isaac J, Doughty H. Emergency red cells first: Rapid response or speed bump? The evolution of a massive transfusion protocol for trauma in a single UK centre. Injury. 46: 1772-8. PMID 26068644 DOI: 10.1016/j.injury.2015.05.046  0.041
2008 Isaac JT, Camara JS, Zeadally S, Marquez JT. A secure vehicle-to-roadside communication payment protocol in vehicular ad hoc networks Computer Communications. 31: 2478-2484. DOI: 10.1016/J.Comcom.2008.03.012  0.041
2015 Dasari BV, Pasquali S, Vohra RS, Smith AM, Taylor MA, Sutcliffe RP, Muiesan P, Roberts KJ, Isaac J, Mirza DF. Extended Versus Standard Lymphadenectomy for Pancreatic Head Cancer: Meta-Analysis of Randomized Controlled Trials. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. PMID 26055135 DOI: 10.1007/s11605-015-2859-3  0.037
2023 Ahuja M, Pandé R, Chugtai S, Brown RM, Cain O, Bartlett DC, Dasari BVM, Marudanayagam R, Roberts KJ, Isaac J, Sutcliffe RP, Chatzizacharias N. Vein Wall Invasion Is a More Reliable Predictor of Oncological Outcomes than Vein-Related Margins after Pancreaticoduodenectomy for Early Stages of Pancreatic Ductal Adenocarcinoma. Diagnostics (Basel, Switzerland). 13. PMID 37998601 DOI: 10.3390/diagnostics13223465  0.037
2018 Dasari BVM, Ionescu MI, Pawlik TM, Hodson J, Sutcliffe RP, Roberts KJ, Muiesan P, Isaac J, Marudanayagam R, Mirza DF. Outcomes of surgical resection of gallbladder cancer in patients presenting with jaundice: A systematic review and meta-analysis. Journal of Surgical Oncology. 118: 477-485. PMID 30259519 DOI: 10.1002/Jso.25186  0.036
2012 Battula N, Tsapralis D, Takhar A, Coldham C, Mayer D, Isaac J, Muiesan P, Sutcliffe RP, Marudanayagam R, Mirza DF, Bramhall SR. Aetio-pathogenesis and the management of spontaneous liver bleeding in the West: a 16-year single-centre experience. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. 14: 382-9. PMID 22568414 DOI: 10.1111/j.1477-2574.2012.00460.x  0.036
2018 Angelico R, Gerlach UA, Gunson BK, Neil D, Mergental H, Isaac J, Muiesan P, Mirza D, Perera MTP. Severe unresolved cholestasis due to unknown aetiology leading to early allograft failure within the first 3 months of liver transplantation. Transplantation. PMID 29470351 DOI: 10.1097/TP.0000000000002139  0.036
2012 Isaac JT, Zeadally S, Cámara JS. A lightweight secure mobile Payment protocol for vehicular ad-hoc networks (VANETs) Electronic Commerce Research. 12: 97-123. DOI: 10.1007/S10660-011-9086-0  0.036
2020 Tirotta F, Giovinazzo F, Hodson J, Yates L, Tan D, Salsano M, Baker D, Sundareyan R, Marudanayagam R, Dasari B, Roberts K, Muiesan P, Isaac J, Mirza D, Mehrzad H, et al. Risk factors to differentiate between benign proximal biliary strictures and perihilar cholangiocarcinoma. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 32321675 DOI: 10.1016/j.hpb.2020.03.023  0.036
2022 Halle-Smith JM, Hodson J, Coldham C, Dasari B, Chatzizacharias N, Marudanayagam R, Sutcliffe R, Isaac J, Mirza DF, Roberts KJ. Three decades of change in pancreatoduodenectomy and future prediction of pathological and operative complexity. The British Journal of Surgery. 109: 247-250. PMID 35026008 DOI: 10.1093/bjs/znab433  0.035
2007 Isaac JT, Camara JS. A secure payment protocol for restricted connectivity scenarios in m-commerce Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4655: 1-10.  0.033
2020 Hatta AAZ, Pathanki AM, Hodson J, Sutcliffe RP, Marudanayagam R, Roberts KJ, Chatzizacharias N, Isaac J, Muiesan P, Taniere P, Mirza DF, Dasari BVM. The effects of resection margin and KRAS status on outcomes after resection of colorectal liver metastases. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 32417170 DOI: 10.1016/j.hpb.2020.04.016  0.033
2018 Vass DG, Hodson J, Isaac J, Marudanayagam R, Mirza DF, Muiesan P, Roberts K, Sutcliffe RP. Utility of drain fluid amylase measurement on the first postoperative day after distal pancreatectomy. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 29802050 DOI: 10.1016/j.hpb.2017.08.016  0.032
2016 Eldeen FZ, Mourad MM, Bhandari M, Roll G, Gunson B, Mergental H, Bramhall S, Isaac J, Muiesan P, Mirza DF, Perera MT. Accepting multiple simultaneous liver offers does not negatively impact transplant outcomes. Transplant International : Official Journal of the European Society For Organ Transplantation. 29: 227-33. PMID 26463509 DOI: 10.1111/tri.12705  0.03
2014 Mourad MM, Liossis C, Gunson BK, Mergental H, Isaac J, Muiesan P, Mirza DF, Perera MT, Bramhall SR. Etiology and management of hepatic artery thrombosis after adult liver transplantation. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 20: 713-23. PMID 24652787 DOI: 10.1002/lt.23874  0.03
2020 Hann A, Lembach H, McKay SC, Perrin M, Isaac J, Oo YH, Mutimer D, Mirza DF, Hartog H, Perera M. Controversies Regarding Shielding and Susceptibility to COVID-19 Disease in Liver transplant Recipients in the United Kingdom. Transplant Infectious Disease : An Official Journal of the Transplantation Society. e13352. PMID 32500939 DOI: 10.1111/tid.13352  0.028
2023 Nelson AN, Shen X, Vekatayogi S, Zhang S, Ozorowski G, Dennis M, Sewall LM, Milligan E, Davis D, Cross KA, Chen Y, van Schooten J, Eudailey J, Isaac J, Memon S, et al. Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques. Biorxiv : the Preprint Server For Biology. PMID 37986885 DOI: 10.1101/2023.11.07.565306  0.027
2020 Pande R, Hodson J, Marudanayagam R, Chatzizacharias N, Dasari B, Muiesan P, Sutcliffe RP, Mirza DF, Isaac J, Roberts KJ. Survival Advantage of Upfront Surgery for Pancreatic Head Cancer Without Preoperative Biliary Drainage. Frontiers in Oncology. 10: 526514. PMID 33251128 DOI: 10.3389/fonc.2020.526514  0.026
2020 Kamarajah S, Giovinazzo F, Roberts KJ, Punia P, Sutcliffe RP, Marudanayagam R, Chatzizacharias N, Isaac J, Mirza DF, Muiesan P, Dasari BV. The role of down staging treatment in the management of locally advanced intrahepatic cholangiocarcinoma: Review of literature and pooled analysis. Annals of Hepato-Biliary-Pancreatic Surgery. 24: 6-16. PMID 32181423 DOI: 10.14701/ahbps.2020.24.1.6  0.025
2020 Schlegel A, Sakuraoka Y, Motwani K, Gourevitch D, Sharif K, Isaac J, Almond M, Desai A, Muiesan P. Outcome after ex situ or ante situm liver resection with hypothermic perfusion and auto-transplantation: A single-centre experience in adult and paediatric patients. Journal of Surgical Oncology. PMID 32705679 DOI: 10.1002/jso.26116  0.024
2018 Dasari BVM, Hodson J, Roberts KJ, Sutcliffe RP, Marudanayagam R, Mirza DF, Isaac J, Muiesan P. Developing and validating a pre-operative risk score to predict post-hepatectomy liver failure. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 30361111 DOI: 10.1016/j.hpb.2018.09.011  0.024
2022 Alarabiyat M, Raza SS, Isaac J, Mirza D, Marudanayagam R, Roberts K, Abradelo M, Bartlett DC, Dasari BV, Sutcliffe RP, Chatzizacharias NA. Incidental gallbladder cancer diagnosis confers survival advantage irrespective of tumour stage and characteristics. World Journal of Gastroenterology. 28: 1996-2007. PMID 35664962 DOI: 10.3748/wjg.v28.i18.1996  0.023
2015 Ajani OO, Isaac JT, Owoeye TF, Akinsiku AA. Exploration of the chemistry and biological properties of pyrimidine as a privilege pharmacophore in therapeutics International Journal of Biological Chemistry. 9: 148-177. DOI: 10.3923/ijbc.2015.148.177  0.023
2017 Mohkam K, Malik Y, Derosas C, Isaac J, Marudanayagam R, Mehrzad H, Mirza DF, Muiesan P, Roberts KJ, Sutcliffe RP. Percutaneous transhepatic cholangiographic endobiliary forceps biopsy versus endoscopic ultrasound fine needle aspiration for proximal biliary strictures: a single-centre experience. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 28302441 DOI: 10.1016/j.hpb.2017.02.001  0.023
2015 Bhogal RH, Hodson J, Bramhall SR, Isaac J, Marudanayagam R, Mirza DF, Muiesan P, Sutcliffe RP. Predictors of early recurrence after resection of colorectal liver metastases. World Journal of Surgical Oncology. 13: 135. PMID 25885912 DOI: 10.1186/s12957-015-0549-y  0.023
2021 McKay SC, Lembach H, Hann A, Okoth K, Anderton J, Nirantharakumar K, Magill L, Torlinska B, Armstrong M, Mascaro J, Inston N, Pinkney T, Ranasinghe A, Borrows R, Ferguson J, ... Isaac J, et al. Health-related quality of life, uncertainty and coping strategies in solid organ transplant recipients during shielding for the COVID-19 pandemic. Transplant International : Official Journal of the European Society For Organ Transplantation. PMID 34378227 DOI: 10.1111/tri.14010  0.023
2021 Bonney GK, Chew CA, Lodge P, Hubbard J, Halazun KJ, Trunecka P, Muiesan P, Mirza DF, Isaac J, Laing RW, Iyer SG, Chee CE, Yong WP, Muthiah MD, Panaro F, et al. Liver transplantation for non-resectable colorectal liver metastases: the International Hepato-Pancreato-Biliary Association consensus guidelines. The Lancet. Gastroenterology & Hepatology. PMID 34506756 DOI: 10.1016/S2468-1253(21)00219-3  0.023
2019 Dasari BVM, Hodson J, Sutcliffe RP, Marudanayagam R, Roberts KJ, Abradelo M, Muiesan P, Mirza DF, Isaac J. Developing and validating a preoperative risk score to predict 90-day mortality after liver resection. Journal of Surgical Oncology. PMID 30637737 DOI: 10.1002/jso.25350  0.023
2015 Sutcliffe RP, Hamoui M, Isaac J, Marudanayagam R, Mirza DF, Muiesan P, Roberts JK. Implementation of an Enhanced Recovery Pathway After Pancreaticoduodenectomy in Patients with Low Drain Fluid Amylase. World Journal of Surgery. 39: 2023-30. PMID 25809067 DOI: 10.1007/s00268-015-3051-3  0.023
2013 Roberts KJ, McCulloch N, Sutcliffe R, Isaac J, Muiesan P, Bramhall S, Mirza D, Marudanayagam R, Mahon BS. Endoscopic ultrasound assessment of lesions of the ampulla of Vater is of particular value in low-grade dysplasia. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. 15: 18-23. PMID 23216775 DOI: 10.1111/j.1477-2574.2012.00542.x  0.022
2015 Mourad MM, Algarni A, Aly MA, Gunson BK, Mergental H, Isaac J, Muiesan P, Mirza D, Perera MT, Bramhall SR. Tumor Characteristics and Long-Term Outcome of Incidental Hepatocellular Carcinoma After Orthotopic Liver Transplant. Experimental and Clinical Transplantation : Official Journal of the Middle East Society For Organ Transplantation. 13: 333-8. PMID 26295183 DOI: 10.6002/ect.2014.0266  0.021
2022 Mckay S, Super J, Marudanayagam R, Daskalakis M, Nijjar R, Isaac J, Richardson M, Singhal R. Setting up a surgical complex gallstone service in a non-HPB unit. Turkish Journal of Surgery. 38: 81-85. PMID 35873754 DOI: 10.47717/turkjsurg.2022.5559  0.021
2023 van der Togt CJT, Van den Bemt B, Aletaha D, Alten R, Chatzidionysiou K, Galloway J, Isaac J, Mulleman D, Verschueren P, Vulto AG, Welsing PMJ, Verhoef L, den Broeder AA. Points to consider for cost-effective use of biological and targeted synthetic DMARDs in inflammatory rheumatic diseases: results from an umbrella review and international Delphi study. Rmd Open. 9. PMID 36863753 DOI: 10.1136/rmdopen-2022-002898  0.02
2022 Patel I, Bartlett D, Dasari BV, Chatzizacharias N, Isaac J, Marudanayagam R, Mirza DF, Roberts JK, Sutcliffe RP. Detection of Colorectal Liver Metastases Using Near-Infrared Fluorescence Imaging During Hepatectomy: Prospective Single Centre UK Study. Journal of Gastrointestinal Cancer. PMID 35616823 DOI: 10.1007/s12029-022-00836-w  0.02
2023 Joshi K, Abradelo M, Bartlett DC, Chatzizacharias N, Dasari BV, Isaac J, Marudanayagam R, Mirza D, Roberts K, Sutcliffe RP. Potential clinical utility of intraoperative fluid amylase measurement during pancreaticoduodenectomy. Annals of Hepato-Biliary-Pancreatic Surgery. PMID 36788121 DOI: 10.14701/ahbps.22-083  0.02
2015 Dasari BV, Rahman R, Khan S, Bennett D, Hodson J, Isaac J, Marudanayagam R, Mirza DF, Muiesan P, Roberts KJ, Sutcliffe RP. Safety and feasibility of an enhanced recovery pathway after a liver resection: prospective cohort study. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 26099347 DOI: 10.1111/hpb.12447  0.019
2017 Schlegel A, Scalera I, Thamara M, Perera PR, Kalisvaart M, Mergental H, Mirza DF, Isaac J, Muiesan P. Impact of donor age in donation after cardiac death liver transplantation: Is the cut-off "60" still of relevance? Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 28885771 DOI: 10.1002/lt.24865  0.019
2014 Roberts KJ, Blanco G, Webber J, Marudanayagam R, Sutcliffe RP, Muiesan P, Bramhall SR, Isaac J, Mirza DF. How severe is diabetes after total pancreatectomy? A case-matched analysis. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. 16: 814-21. PMID 24344937 DOI: 10.1111/hpb.12203  0.018
2021 Nutu OA, Sneiders D, Mirza D, Isaac J, Perera MTPR, Hartog H. Safety of intra-operative blood salvage during liver transplantation in patients with hepatocellular carcinoma, a propensity score-matched survival analysis. Transplant International : Official Journal of the European Society For Organ Transplantation. PMID 34724271 DOI: 10.1111/tri.14150  0.018
2017 Angelico R, Khan S, Dasari B, Marudanayagam R, Sutcliffe RP, Muiesan P, Isaac J, Mirza D, Roberts KJ. Is routine hepaticojejunostomy at the time of unplanned surgical bypass required in the era of self-expanding metal stents? Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 28223041 DOI: 10.1016/j.hpb.2016.12.009  0.018
2016 Zahr Eldeen F, Roll GR, Derosas C, Rao R, Khan MS, Gunson BK, Hodson J, Mergental H, Ferraz-Neto BH, Isaac J, Muiesan P, Mirza DF, Iqbal A, Perera MT. Preoperative Thromboelastography as a Sensitive Tool Predicting Those at Risk of Developing Early Hepatic Artery Thrombosis After Adult Liver Transplantation. Transplantation. 100: 2382-2390. PMID 27780186 DOI: 10.1097/TP.0000000000001395  0.018
2015 Hartog H, May CJ, Corbett C, Phillips A, Tomlinson JW, Mergental H, Isaac J, Bramhall S, Mirza DF, Muiesan P, Perera MT. Early occurrence of new-onset diabetes after transplantation is related to type of liver graft and warm ischaemic injury. Liver International : Official Journal of the International Association For the Study of the Liver. 35: 1739-47. PMID 25349066 DOI: 10.1097/00007890-201407151-00529  0.018
2020 Kalisvaart M, Broadhurst D, Marcon F, Pande R, Schlegel A, Sutcliffe R, Marudanayagam R, Mirza D, Chatzizacharias N, Abradelo M, Muiesan P, Isaac J, Ma YT, McConville C, Roberts K. Recurrence patterns of pancreatic cancer after pancreatoduodenectomy: systematic review and a single-centre retrospective study. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 32046922 DOI: 10.1016/j.hpb.2020.01.005  0.017
2011 Tariciotti L, Rocha C, Perera MT, Gunson BK, Bramhall SR, Isaac J, Buckels JA, Mayer AD, Muiesan P, Mirza DF. Is it time to extend liver acceptance criteria for controlled donors after cardiac death? Transplantation. 92: 1140-6. PMID 21946173 DOI: 10.1097/TP.0b013e318232babe  0.017
2010 Isaac JT, Zeadally S, Cámara JS. Security attacks and solutions for vehicular ad hoc networks Iet Communications. 4: 894-903. DOI: 10.1049/Iet-Com.2009.0191  0.017
2006 Isaac JT, Camara JS, Manzanares AI, Castro MC. Payment in a Kiosk Centric Model with mobile and low computational power devices Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 3984: 798-807. DOI: 10.1007/11751649_88  0.016
2018 Boteon APCS, Boteon YL, Hodson J, Osborne H, Isaac J, Marudanayagam R, Mirza DF, Muiesan P, Roberts JK, Sutcliffe RP. Multivariable analysis of predictors of unplanned hospital readmission after pancreaticoduodenectomy: development of a validated risk score. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 30049642 DOI: 10.1016/j.hpb.2018.06.1802  0.016
2021 Bari H, Thiyagarajan UM, Brown R, Roberts KJ, Chatzizacharias N, Marudanayagam R, Muiesan P, Isaac J, Mirza DF, Sutcliffe RP, Dasari BVM. Liver Resection and role of Extended Histology (LiREcH study) in patients with multifocal colorectal cancer liver metastases. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 34024732 DOI: 10.1016/j.hpb.2021.03.018  0.015
2019 Roberts KJ, Boteon APCS, Marcon F, Abradelo M, Dasari B, Muiesan P, Marudanayagam R, Sutcliffe RP, Isaac J, Mirza DF. Risk adjusted assessment of individual surgeon's pancreatic fistula outcomes. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 31445781 DOI: 10.1016/j.hpb.2019.07.017  0.015
2015 Mabrouk Mourad M, Liossis C, Kumar S, Gunson BK, Mergental H, Isaac J, Bramhall SR, Muiesan P, Mirza DF, Thamara P R Perera M. Vasculobiliary complications following adult right lobe split liver transplantation from the perspective of reconstruction techniques. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 21: 63-71. PMID 25302412 DOI: 10.1002/lt.24015  0.015
2017 Roberts KJ, Schrem H, Hodson J, Angelico R, Dasari BVM, Coldham CA, Marudanayagam R, Sutcliffe RP, Muiesan P, Isaac J, Mirza DF. Pancreas exocrine replacement therapy is associated with increased survival following pancreatoduodenectomy for periampullary malignancy. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 28711377 DOI: 10.1016/j.hpb.2017.05.009  0.015
2020 Chew CA, Iyer SG, Chieh Kow AW, Madhavan K, Teng Wong AS, Halazun KJ, Battula N, Scalera I, Angelico R, Farid S, Buchholz BM, Rotellar F, Chi-Yan Chan A, Kim JM, Wang CC, ... ... Isaac J, et al. An international multicentre study of protocols for liver transplantation during a pandemic: A case for quadripartite equipoise. Journal of Hepatology. PMID 32454041 DOI: 10.1016/j.jhep.2020.05.023  0.014
2016 Dasari BV, Roberts KJ, Hodson J, Stevens L, Smith AM, Hubscher SG, Isaac J, Muiesan P, Sutcliffe RP, Marudanayagam R, Mirza DF. A model to predict survival following pancreaticoduodenectomy for malignancy based on tumour site, stage and lymph node ratio. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. 18: 332-8. PMID 27037202 DOI: 10.1016/j.hpb.2015.11.008  0.014
2018 Dasari BVM, Al-Shakhshir S, Pawlik TM, Shah T, Marudanayagam R, Sutcliffe RP, Mirza DF, Muiesan P, Roberts KJ, Isaac J. Outcomes of Surgical and Endoscopic Resection of Duodenal Neuroendocrine Tumours (NETs): a Systematic Review of the Literature. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. PMID 29869091 DOI: 10.1007/S11605-018-3825-7  0.014
2017 Halle-Smith JM, Vinuela E, Brown RM, Hodson J, Zia Z, Bramhall SR, Marudanayagam R, Sutcliffe RP, Mirza DF, Muiesan P, Isaac J, Roberts KJ. A comparative study of risk factors for pancreatic fistula after pancreatoduodenectomy or distal pancreatectomy. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 28522378 DOI: 10.1016/j.hpb.2017.04.013  0.014
2019 Dasari BVM, Hodson J, Sutcliffe RP, Marudanayagam R, Roberts KJ, Abradelo M, Muiesan P, Mirza DF, Isaac J. Developing and validating a preoperative risk score to predict 90-day mortality after liver resection. Journal of Surgical Oncology. PMID 30737797 DOI: 10.1002/jso.25405  0.014
2020 Attard JA, Farrugia A, Pathanki A, Roberts KJ, Dasari B, Isaac J, Ma YT, Chatzizacharias NA. Treatment Strategies for the Optimal Management of Locally Advanced Pancreatic Adenocarcinoma With Curative Intent: A Systematic Review. Pancreas. 49: 1264-1275. PMID 33122513 DOI: 10.1097/MPA.0000000000001694  0.014
2023 Menon K, Vijayashanker A, Murphy J, Line PD, Isaac J, Adair A, Prasad R, Thorburn D. Liver transplantation for isolated unresectable colorectal liver metastases - Protocol for a service evaluation in the United Kingdom - UKCoMET study. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 36948901 DOI: 10.1016/j.hpb.2023.02.011  0.013
2018 Bansal SS, Hodson J, Khalil K, Dasari B, Marudanayagam R, Sutcliffe RP, Isaac J, Roberts KJ. Distinct risk factors for early and late blood transfusion following pancreaticoduodenectomy. Hepatobiliary & Pancreatic Diseases International : Hbpd Int. PMID 30054170 DOI: 10.1016/j.hbpd.2018.07.001  0.012
2024 Dey M, Busby A, Isaac J, Pratt A, Ndosi M, Young A, Lempp H, Nikiphorou E. Personalised care packages for people with rheumatoid arthritis: a mixed-methods study. Rmd Open. 10. PMID 38191212 DOI: 10.1136/rmdopen-2023-003483  0.012
2024 Ahuja M, Joshi K, Coldham C, Muiesan P, Dasari B, Abradelo M, Marudanayagam R, Mirza D, Isaac J, Bartlett D, Chatzizacharias NA, Sutcliffe RP, Roberts KJ. Hepatic vein reconstruction during hepatectomy: A feasible and underused technique. Hepatobiliary & Pancreatic Diseases International : Hbpd Int. PMID 38278672 DOI: 10.1016/j.hbpd.2024.01.002  0.011
2014 Battula N, Tsapralis D, Mayer D, Isaac J, Muiesan P, Sutcliffe RP, Bramhall S, Mirza D, Marudanayagam R. Repeat liver resection for recurrent colorectal metastases: a single-centre, 13-year experience. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. 16: 157-63. PMID 23530978 DOI: 10.1111/hpb.12096  0.011
2007 Isaac JT, Cámara JS. Anonymous payment in a client centric model for digital ecosystems Proceedings of the 2007 Inaugural Ieee-Ies Digital Ecosystems and Technologies Conference, Dest 2007. 422-427. DOI: 10.1109/DEST.2007.372011  0.011
2015 Rocha C, Perera MT, Roberts K, Bonney G, Gunson B, Nightingale P, Bramhall SR, Isaac J, Muiesan P, Mirza DF. Outcomes after liver transplantation of patients with Indo-Asian ethnicity. Transplantation. 99: 860-6. PMID 25211517 DOI: 10.1097/TP.0000000000000411  0.01
2023 Shah T, Manas DM, Ford SJ, Dasari BVM, Gibbs P, Venkataraman H, Moore J, Hughes S, Elshafie M, Karkhanis S, Smith S, Hoti E, O'Toole D, Caplin ME, Isaac J, et al. Where Are We Now with Liver Transplantation in Neuroendocrine Neoplasms? The Place of Liver Transplantation for Grades 1 and 2 Well-Differentiated Unresectable Liver Metastatic Neuroendocrine Tumours. Current Oncology Reports. PMID 36648705 DOI: 10.1007/s11912-022-01343-8  0.01
2019 Dasari BV, Kamarajah SK, Hodson J, Pawlik TM, Vauthey JN, Ma YT, Punia P, Coldham C, Abradelo M, Roberts KJ, Marudanayagam R, Sutcliffe RP, Muiesan P, Mirza DF, Isaac J. Development and validation of a risk score to predict the overall survival following surgical resection of hepatocellular carcinoma in non-cirrhotic liver. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 31416786 DOI: 10.1016/J.Hpb.2019.07.007  0.01
2022 Raza SS, Nutu A, Powell-Brett S, Marchetti A, Perri G, Carvalheiro Boteon A, Hodson J, Chatzizacharias N, Dasari BV, Isaac J, Abradelo M, Marudanayagam R, Mirza DF, Roberts JK, Marchegiani G, et al. Early postoperative risk stratification in patients with pancreatic fistula after pancreaticoduodenectomy. Surgery. 173: 492-500. PMID 37530481 DOI: 10.1016/j.surg.2022.09.008  0.01
2022 Pande R, Chughtai S, Ahuja M, Brown R, Bartlett DC, Dasari BV, Marudanayagam R, Mirza D, Roberts K, Isaac J, Sutcliffe RP, Chatzizacharias NA. Para-aortic lymph node involvement should not be a contraindication to resection of pancreatic ductal adenocarcinoma. World Journal of Gastrointestinal Surgery. 14: 429-441. PMID 35734625 DOI: 10.4240/wjgs.v14.i5.429  0.01
2022 Nutu A, Wilson M, Ross E, Joshi K, Sutcliffe R, Roberts K, Marudanayagam R, Muiesan P, Chatzizacharias N, Mirza D, Isaac J, Dasari BVM. Influence of middle hepatic vein resection during right or left hepatectomy on post hepatectomy outcomes. Annals of Hepato-Biliary-Pancreatic Surgery. PMID 35599354 DOI: 10.14701/ahbps.21-159  0.01
2021 Masson S, Taylor R, Whitney J, Adair A, Attia M, Gibbs P, Grammatikopoulos T, Isaac J, Marshall A, Mirza D, Prachalias A, Watson S, Manas D, Forsythe J, Thorburn D. A coordinated national UK liver transplant program response, prioritizing waitlist recipients with the highest need, provided excellent outcomes during the first wave of the COVID-19 pandemic. Clinical Transplantation. e14563. PMID 34913525 DOI: 10.1111/ctr.14563  0.01
2021 Kamarajah SK, Chatzizacharias N, Hodson J, Marcon F, Kalisvaart M, Punia P, Ting Ma Y, Dasari B, Marudanayagam R, Sutcliffe RP, Muiesan P, Mirza DF, Isaac J, Roberts KJ. Intention to treat outcomes among patients with pancreatic cancer treated using International Study Group on Pancreatic Surgery recommended pathways for resectable and borderline resectable disease. Anz Journal of Surgery. PMID 33576568 DOI: 10.1111/ans.16643  0.01
2020 Mueller M, Kalisvaart M, O'Rourke J, Shetty S, Parente A, Muller X, Isaac J, Muellhaupt B, Muiesan P, Shah T, Clavien PA, Schlegel A, Dutkowski P. Hypothermic Oxygenated Liver Perfusion (HOPE) Prevents Tumor Recurrence in Liver Transplantation From Donation After Circulatory Death. Annals of Surgery. PMID 32889870 DOI: 10.1097/SLA.0000000000004258  0.01
2020 Pande R, Hodson J, Marudanayagam R, Mirza D, Isaac J, Roberts KJ. Venous resection at pancreaticoduodenectomy can be safely performed in the presence of jaundice. Hepatobiliary & Pancreatic Diseases International : Hbpd Int. PMID 32694048 DOI: 10.1016/j.hbpd.2020.07.001  0.01
2020 Attard JA, Isaac J, Roberts K, Faulkner T, Chatzizacharias NA. Resection of Replaced Common Hepatic Artery in Locally Advanced Pancreatic Cancer: A Case Report and Analysis of Technical and Oncological Implications. Pancreas. 49: e31-e33. PMID 32282777 DOI: 10.1097/MPA.0000000000001533  0.01
2019 Schlegel A, Sakuraoka Y, Kalisvaart M, Coldham C, Isaac J, Muiesan P. Future liver remnant portal or hepatic vein reconstruction at stage I of ALPPS-How far can we push the boundaries? Journal of Surgical Oncology. PMID 31309549 DOI: 10.1002/jso.25618  0.01
2018 Schlegel A, Muller X, Kalisvaart M, Muellhaupt B, Perera M, Isaac J, Clavien PA, Muiesan P, Dutkowski P. Outcomes of liver transplantations from donation after circulatory death (DCD) treated by hypothermic oxygenated perfusion (HOPE) before implantation. Journal of Hepatology. PMID 30342115 DOI: 10.1016/j.jhep.2018.10.005  0.01
2018 O'Reilly DJ, Hodson J, Pike TW, Marudanayagam R, Sutcliffe RP, Muiesan P, Isaac J, A Lodge JP, Mirza DF, Roberts KJ. The rate of false-positive diagnosis of colorectal liver metastases in patients undergoing resection with the development of a novel, externally validated risk score. Surgery. PMID 29751969 DOI: 10.1016/j.surg.2018.02.010  0.01
2018 Khalil K, Bansal S, Ayaani S, Hodson J, Lam FT, Khan S, Ahmad J, Isaac J, Muiesan P, Mirza D, Dasari B, Marudanayagam R, Sutcliffe RP, Marangoni G, Roberts KJ. Does blood group affect survival following pancreatoduodenectomy for periampullary malignancy? Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 29705345 DOI: 10.1016/j.hpb.2018.03.009  0.01
2018 Marcon F, Schlegel A, Bartlett DC, Kalisvaart M, Bishop D, Mergental H, Roberts KJ, Mirza DF, Isaac J, Muiesan P, Perera MT. Utilization of Declined Liver Grafts Yields Comparable Transplant Outcomes and Previous Decline Should Not Be a Deterrent to Graft Use. Transplantation. 102: e211-e218. PMID 29702538 DOI: 10.1097/TP.0000000000002127  0.01
2017 Schlegel A, Kalisvaart M, Scalera I, Laing RW, Mergental H, Mirza DF, Perera T, Isaac J, Dutkowski P, Muiesan P. The UK-DCD-Risk-Score: a new proposal to define futility in Donation after Circulatory Death liver transplantation. Journal of Hepatology. PMID 29155020 DOI: 10.1016/j.jhep.2017.10.034  0.01
2017 Gavriilidis P, Sutcliffe RP, Hodson J, Marudanayagam R, Isaac J, Azoulay D, Roberts KJ. Simultaneous versus delayed hepatectomy for synchronous colorectal liver metastases: a systematic review and meta-analysis. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. PMID 28888775 DOI: 10.1016/j.hpb.2017.08.008  0.01
2016 Battula NR, Plato M, Anbarasan R, Perera MT, Ong E, Roll GR, Neto BF, Mergental H, Isaac J, Muiesan P, Sharif K, Mirza DF. Intention to Split Policy: A Successful Strategy in a Combined Pediatric and Adult Liver Transplant Center. Annals of Surgery. PMID 27257738 DOI: 10.1097/SLA.0000000000001816  0.01
2015 Perera M, Mergental H, Stephenson B, Roll GR, Cilliers H, Liang R, Angelico R, Hubscher S, Neil DA, Reynolds G, Isaac J, Adams DA, Afford S, Mirza DF, Muiesan P. First human liver transplantation using a marginal allograft resuscitated by normothermic machine perfusion. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 26566737 DOI: 10.1002/Lt.24369  0.01
2015 Roberts KJ, Sutcliffe RP, Marudanayagam R, Hodson J, Isaac J, Muiesan P, Navarro A, Patel K, Jah A, Napetti S, Adair A, Lazaridis S, Prachalias A, Shingler G, Al-Sarireh B, et al. Scoring System to Predict Pancreatic Fistula After Pancreaticoduodenectomy: A UK Multicenter Study. Annals of Surgery. PMID 25371115 DOI: 10.1097/SLA.0000000000000997  0.01
2014 Roberts KJ, Hodson J, Mehrzad H, Marudanayagam R, Sutcliffe RP, Muiesan P, Isaac J, Bramhall SR, Mirza DF. A preoperative predictive score of pancreatic fistula following pancreatoduodenectomy. Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. 16: 620-8. PMID 24246089 DOI: 10.1111/hpb.12186  0.01
2014 Lomaglio L, Isaac J, Mirza D, Perera MT, Muiesan P. Management of synchronous vascular and ductal anomalies in living donor liver transplantation for hepatic epithelioid hemangioendothelioma. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 20: 247-9. PMID 24166881 DOI: 10.1002/lt.23781  0.01
2014 Isaac JT, Zeadally S. Secure mobile payment systems It Professional. 16: 36-43. DOI: 10.1109/MITP.2014.40  0.01
2011 Banz V, Olliff S, Taniere P, Mayer D, Isaac J. Liver tumours in patients with Abernethy malformation. Anz Journal of Surgery. 81: 640-1. PMID 22295400  0.01
2011 Aroori S, Puneet P, Bramhall SR, Muiesan P, Mayer AD, Mirza DF, Buckels JC, Isaac J. Outcomes comparing a pancreaticogastrostomy (PG) and a pancreaticojejunostomy (PJ) after a pancreaticoduodenectomy (PD). Hpb : the Official Journal of the International Hepato Pancreato Biliary Association. 13: 723-31. PMID 21929673 DOI: 10.1111/j.1477-2574.2011.00363.x  0.01
2011 Varma V, Perera MT, Olliff S, Taniere P, Isaac J, Mirza DF. Cytomegalovirus ileitis causing massive gastrointestinal haemorrhage in a patient following hepatic resection. Tropical Gastroenterology : Official Journal of the Digestive Diseases Foundation. 32: 145-7. PMID 21922884  0.01
2005 Shah T, Isaac J, Adams D, Kelly D. Development of hepatopulmonary syndrome and portopulmonary hypertension in a paediatric liver transplant patient. Pediatric Transplantation. 9: 127-31. PMID 15667626 DOI: 10.1111/j.1399-3046.2004.00221.x  0.01
2004 Tan KB, Premasiri MK, Isaac J, Raju GC. Mushroom bezoar: a rare cause of small intestinal obstruction. Pathology. 36: 207-8. PMID 15203763 DOI: 10.1080/00313020410001672077  0.01
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