Alan Bernstein - Publications

Affiliations: 
Canadian Institutes of Health Research, Toronto, Ontario, Canada 

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2008 Higashi M, Maruta N, Bernstein A, Ikenaka K, Hitoshi S. Mood stabilizing drugs expand the neural stem cell pool in the adult brain through activation of notch signaling. Stem Cells (Dayton, Ohio). 26: 1758-67. PMID 18467661 DOI: 10.1634/Stemcells.2007-1032  0.328
2007 Thornhill PB, Cohn JB, Drury G, Stanford WL, Bernstein A, Desbarats J. A proteomic screen reveals novel Fas ligand interacting proteins within nervous system Schwann cells. Febs Letters. 581: 4455-62. PMID 17761170 DOI: 10.1016/J.Febslet.2007.08.025  0.317
2007 Das S, Raj L, Zhao B, Kimura Y, Bernstein A, Aaronson SA, Lee SW. Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation. Cell. 130: 624-37. PMID 17719541 DOI: 10.1016/J.Cell.2007.06.013  0.339
2006 Frese KK, Latorre IJ, Chung SH, Caruana G, Bernstein A, Jones SN, Donehower LA, Justice MJ, Garner CC, Javier RT. Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressor. The Embo Journal. 25: 1406-17. PMID 16511562 DOI: 10.1038/Sj.Emboj.7601030  0.322
2006 Alexson TO, Hitoshi S, Coles BL, Bernstein A, van der Kooy D. Notch signaling is required to maintain all neural stem cell populations--irrespective of spatial or temporal niche. Developmental Neuroscience. 28: 34-48. PMID 16508302 DOI: 10.1159/000090751  0.333
2005 Naim E, Bernstein A, Bertram JF, Caruana G. Mutagenesis of the epithelial polarity gene, discs large 1, perturbs nephrogenesis in the developing mouse kidney. Kidney International. 68: 955-65. PMID 16105026 DOI: 10.1111/J.1523-1755.2005.00489.X  0.383
2005 Tachibana K, Jones N, Dumont DJ, Puri MC, Bernstein A. Selective role of a distinct tyrosine residue on Tie2 in heart development and early hematopoiesis. Molecular and Cellular Biology. 25: 4693-702. PMID 15899871 DOI: 10.1128/Mcb.25.11.4693-4702.2005  0.394
2004 Hirashima M, Bernstein A, Stanford WL, Rossant J. Gene-trap expression screening to identify endothelial-specific genes. Blood. 104: 711-8. PMID 15090446 DOI: 10.1182/Blood-2004-01-0254  0.379
2004 Kimura Y, Jones N, Klüppel M, Hirashima M, Tachibana K, Cohn JB, Wrana JL, Pawson T, Bernstein A. Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages. Proceedings of the National Academy of Sciences of the United States of America. 101: 6015-20. PMID 15067126 DOI: 10.1073/Pnas.0305363101  0.405
2003 Nguyen MM, Nguyen ML, Caruana G, Bernstein A, Lambert PF, Griep AE. Requirement of PDZ-containing proteins for cell cycle regulation and differentiation in the mouse lens epithelium. Molecular and Cellular Biology. 23: 8970-81. PMID 14645510 DOI: 10.1128/Mcb.23.24.8970-8981.2003  0.365
2003 Puri MC, Bernstein A. Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 100: 12753-8. PMID 14530387 DOI: 10.1073/Pnas.2133552100  0.39
2003 Ito CY, Li CY, Bernstein A, Dick JE, Stanford WL. Hematopoietic stem cell and progenitor defects in Sca-1/Ly-6A-null mice. Blood. 101: 517-23. PMID 12393491 DOI: 10.1182/Blood-2002-06-1918  0.338
2002 Velazquez L, Cheng AM, Fleming HE, Furlonger C, Vesely S, Bernstein A, Paige CJ, Pawson T. Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice. The Journal of Experimental Medicine. 195: 1599-611. PMID 12070287 DOI: 10.1084/Jem.20011883  0.353
2002 Hitoshi S, Alexson T, Tropepe V, Donoviel D, Elia AJ, Nye JS, Conlon RA, Mak TW, Bernstein A, van der Kooy D. Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes & Development. 16: 846-58. PMID 11937492 DOI: 10.1101/Gad.975202  0.334
2002 Kimura Y, Hart A, Hirashima M, Wang C, Holmyard D, Pittman J, Pang XL, Jackson CW, Bernstein A. Zinc finger protein, Hzf, is required for megakaryocyte development and hemostasis. The Journal of Experimental Medicine. 195: 941-52. PMID 11927637 DOI: 10.1084/Jem.20011522  0.328
2002 Taniguchi Y, Karlström H, Lundkvist J, Mizutani T, Otaka A, Vestling M, Bernstein A, Donoviel D, Lendahl U, Honjo T. Notch receptor cleavage depends on but is not directly executed by presenilins. Proceedings of the National Academy of Sciences of the United States of America. 99: 4014-9. PMID 11891288 DOI: 10.1073/Pnas.052017699  0.312
2002 Vallis KA, Chen Z, Stanford WL, Yu M, Hill RP, Bernstein A. Identification of radiation-responsive genes in vitro using a gene trap strategy predicts for modulation of expression by radiation in vivo. Radiation Research. 157: 8-18. PMID 11754636 DOI: 10.1667/0033-7587(2002)157[0008:Iorrgi]2.0.Co;2  0.346
2002 Lutz MA, Gervais F, Bernstein A, Hattel AL, Correll PH. STK receptor tyrosine kinase regulates susceptibility to infection with Listeria monocytogenes. Infection and Immunity. 70: 416-8. PMID 11748211 DOI: 10.1128/Iai.70.1.416-418.2002  0.317
2001 Caruana G, Bernstein A. Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene Molecular and Cellular Biology. 21: 1475-1483. PMID 11238884 DOI: 10.1128/Mcb.21.5.1475-1483.2001  0.405
2000 Hart AH, Reventar R, Bernstein A. Genetic analysis of ETS genes in C. elegans Oncogene. 19: 6400-6408. PMID 11175356 DOI: 10.1038/Sj.Onc.1204040  0.324
2000 Hart A, Melet F, Grossfeld P, Chien K, Jones C, Tunnacliffe A, Favier R, Bernstein A. Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia Immunity. 13: 167-177. PMID 10981960 DOI: 10.1016/S1074-7613(00)00017-0  0.326
2000 Dror Y, Leaker M, Caruana G, Bernstein A, Freedman MH. Mastocytosis cells bearing a c-kit activating point mutation are characterized by hypersensitivity to stem cell factor and increased apoptosis British Journal of Haematology. 108: 729-736. PMID 10792276 DOI: 10.1046/J.1365-2141.2000.01935.X  0.38
2000 Hidaka M, Caruana G, Stanford WL, Sam M, Correll PH, Bernstein A. Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells Mechanisms of Development. 90: 3-15. PMID 10585558 DOI: 10.1016/S0925-4773(99)00234-8  0.397
1999 Donoviel DB, Hadjantonakis AK, Ikeda M, Zheng H, Hyslop PSG, Bernstein A. Mice lacking both presenilin genes exhibit early embryonic patterning defects Genes and Development. 13: 2801-2810. PMID 10557208 DOI: 10.1101/Gad.13.21.2801  0.363
1999 Persons DA, Paulson RF, Loyd MR, Herley MT, Bodner SM, Bernstein A, Correll PH, Ney PA. Fv2 encodes a truncated form of the Stk receptor tyrosine kinase Nature Genetics. 23: 159-165. PMID 10508511 DOI: 10.1038/13787  0.409
1999 Hidaka M, Stanford WL, Bernstein A. Conditional requirement for the Flk-1 receptor in the in vitro generation of early hematopoietic cells Proceedings of the National Academy of Sciences of the United States of America. 96: 7370-7375. PMID 10377421 DOI: 10.1073/Pnas.96.13.7370  0.391
1998 Donoviel DB, Donoviel MS, Fan E, Hadjantonakis AK, Bernstein A. Cloning and characterization of Sel-1l, a murine homolog of the C. elegans sel-1 gene Mechanisms of Development. 78: 203-207. PMID 9858735 DOI: 10.1016/S0925-4773(98)00146-4  0.344
1998 Stanford WL, Caruana G, Vallis KA, Inamdar M, Hidaka M, Bautch VL, Bernstein A. Expression trapping: Identification of novel genes expressed in hematopoietic and endothelial lineages by gene trapping in ES cells Blood. 92: 4622-4631. PMID 9845528 DOI: 10.1182/Blood.V92.12.4622  0.375
1998 Potter M, Bernstein A, Lee JM. The wst gene regulates multiple forms of thymocyte apoptosis Cellular Immunology. 188: 111-117. PMID 9756641 DOI: 10.1006/Cimm.1998.1346  0.311
1998 Sam M, Wurst W, Klüppel M, Jin O, Heng H, Bernstein A. Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif Developmental Dynamics. 212: 304-317. PMID 9626505 DOI: 10.1002/(Sici)1097-0177(199806)212:2<304::Aid-Aja15>3.0.Co;2-3  0.376
1998 Fischer KD, Kong YY, Nishina H, Tedford K, Marengère LE, Kozieradzki I, Sasaki T, Starr M, Chan G, Gardener S, Nghiem MP, Bouchard D, Barbacid M, Bernstein A, Penninger JM. Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor. Current Biology : Cb. 8: 554-62. PMID 9601639 DOI: 10.1016/S0960-9822(98)70224-6  0.362
1998 Arama E, Yanai A, Kilfin G, Bernstein A, Motro B. Murine NIMA-related kinases are expressed in patterns suggesting distinct functions in gametogenesis and a role in the nervous system. Oncogene. 16: 1813-23. PMID 9583679 DOI: 10.1038/Sj.Onc.1201710  0.366
1998 Klüppel M, Huizinga JD, Malysz J, Bernstein A. Developmental origin and Kit-dependent development of the interstitial cells of Cajal in the mammalian small intestine Developmental Dynamics. 211: 60-71. PMID 9438424 DOI: 10.1002/(Sici)1097-0177(199801)211:1<60::Aid-Aja6>3.0.Co;2-5  0.339
1997 Nishina H, Bachmann M, Oliveira-dos-Santos AJ, Kozieradzki I, Fischer KD, Odermatt B, Wakeham A, Shahinian A, Takimoto H, Bernstein A, Mak TW, Woodgett JR, Ohashi PS, Penninger JM. Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes. The Journal of Experimental Medicine. 186: 941-53. PMID 9294148 DOI: 10.1084/Jem.186.6.941  0.3
1997 Potter MD, Shinpock SG, Popp RA, Godfrey V, Carpenter DA, Bernstein A, Johnson DK, Rinchik EM. Mutations in the murine fitness 1 gene result in defective hematopoiesis. Blood. 90: 1850-7. PMID 9292517 DOI: 10.1182/Blood.V90.5.1850  0.376
1997 Shalaby F, Ho J, Stanford WL, Fischer KD, Schuh AC, Schwartz L, Bernstein A, Rossant J. A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesis. Cell. 89: 981-90. PMID 9200616 DOI: 10.1016/S0092-8674(00)80283-4  0.383
1997 Klüppel M, Nagle DL, Bucan M, Bernstein A. Long-range genomic rearrangements upstream of Kit dysregulate the developmental pattern of Kit expression in W57 and W(banded) mice and interfere with distinct steps in melanocyte development Development. 124: 65-77. PMID 9006068  0.315
1996 Piao X, Paulson R, Van Der Geer P, Pawson T, Bernstein A. Oncogenic mutation in the Kit receptor tyrosine kinase alters substrate specificity and induces degradation of the protein tyrosine phosphatase SHP-1 Proceedings of the National Academy of Sciences of the United States of America. 93: 14665-14669. PMID 8962111 DOI: 10.1073/Pnas.93.25.14665  0.363
1996 Sam M, Wurst W, Forrester L, Vauti F, Heng H, Bernstein A. A novel family of repeat sequences in the mouse genome responsive to retinoic acid. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 741-8. PMID 8854861 DOI: 10.1007/S003359900224  0.352
1996 Paulson RF, Vesely S, Siminovitch KA, Bernstein A. Signalling by the W/Kit receptor tyrosine kinase is negatively regulated in vivo by the protein tyrosine phosphatase Shp1 Nature Genetics. 13: 309-315. PMID 8673130 DOI: 10.1038/Ng0796-309  0.373
1996 Mélet F, Motro B, Rossi DJ, Zhang L, Bernstein A. Generation of a novel Fli-1 protein by gene targeting leads to a defect in thymus development and a delay in Friend virus-induced erythroleukemia. Molecular and Cellular Biology. 16: 2708-18. PMID 8649378 DOI: 10.1128/Mcb.16.6.2708  0.336
1996 Forrester LM, Nagy A, Sam M, Watt A, Stevenson L, Bernstein A, Joyner AL, Wurst W. An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proceedings of the National Academy of Sciences of the United States of America. 93: 1677-82. PMID 8643689 DOI: 10.1073/Pnas.93.4.1677  0.576
1996 Piao X, Bernstein A. A point mutation in the catalytic domain of c-kit induces growth factor independence, tumorigenicity, and differentiation of mast cells Blood. 87: 3117-3123. PMID 8605325 DOI: 10.1182/Blood.V87.8.3117.Bloodjournal8783117  0.406
1995 Puri MC, Rossant J, Alitalo K, Bernstein A, Partanen J. The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells Embo Journal. 14: 5884-5891. PMID 8846781 DOI: 10.1002/J.1460-2075.1995.Tb00276.X  0.343
1995 Paulson RF, Bernstein A. Receptor tyrosine kinases and the regulation of hematopoiesis Seminars in Immunology. 7: 267-277. PMID 8520031 DOI: 10.1006/Smim.1995.0031  0.374
1995 Harvey M, Vogel H, Morris D, Bradley A, Bernstein A, Donehower LA. A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice Nature Genetics. 9: 305-311. PMID 7773294 DOI: 10.1038/Ng0395-305  0.302
1995 Kao KR, Bernstein A. Expression of Xkl-1, a Xenopus gene related to mammalian c-kit, in dorsal embryonic tissue Mechanisms of Development. 50: 57-69. PMID 7605752 DOI: 10.1016/0925-4773(94)00325-H  0.356
1995 Brunkow ME, Nagle DL, Bernstein A, Bucan M. A 1.8-Mb YAC contig spanning three members of the receptor tyrosine kinase gene family (Pdgfra, Kit, and Flk1) on mouse chromosome 5 Genomics. 25: 421-432. PMID 7540588 DOI: 10.1016/0888-7543(95)80042-K  0.328
1994 Lee JM, Abrahamson JL, Bernstein A. DNA damage, oncogenesis and the p53 tumour-suppressor gene. Mutation Research. 307: 573-81. PMID 7514730 DOI: 10.1016/0027-5107(94)90267-4  0.345
1994 Piao X, Curtis JE, Minkin S, Minden MD, Bernstein A. Expression of the Kit and KitA receptor isoforms in human acute myelogenous leukemia. Blood. 83: 476-81. PMID 7506952 DOI: 10.1182/Blood.V83.2.476.Bloodjournal832476  0.36
1993 Lee JM, Bernstein A. p53 Mutations increase resistance to ionizing radiation Proceedings of the National Academy of Sciences of the United States of America. 90: 5742-5746. PMID 8516323 DOI: 10.1073/Pnas.90.12.5742  0.339
1993 Irish JC, Bernstein A. Oncogenes in head and neck cancer Laryngoscope. 103: 42-52. PMID 8421418 DOI: 10.1288/00005537-199301000-00009  0.317
1993 Bernstein A. Molecular genetic approaches to the elucidation of hematopoietic stem cell function Stem Cells. 11: 31-35. PMID 7691325 DOI: 10.1002/Stem.5530110806  0.326
1993 Motro B, Bernstein A. Dynamic changes in ovarian c-kit and Steel expression during the estrous reproductive cycle Developmental Dynamics. 197: 69-79. PMID 7691275 DOI: 10.1002/Aja.1001970107  0.389
1993 Bernstein A. Receptor tyrosine kinases and the control of hematopoiesis Seminars in Developmental Biology. 4: 351-358. DOI: 10.1006/Sedb.1993.1039  0.369
1992 Forrester LM, Brunkow M, Bernstein A. Proto-oncogenes in mammalian development. Current Opinion in Genetics & Development. 2: 38-44. PMID 1633424 DOI: 10.1016/S0959-437X(05)80319-3  0.399
1992 Letwin K, Mizzen. L. L, Motro B, Ben-David Y, Bernstein A, Pawson T. A mammalian dual specificity protein kinase, Nek1, is related to the NIMA cell cycle regulator and highly expressed in meiotic germ cells Embo Journal. 11: 3521-3531. PMID 1382974 DOI: 10.1002/J.1460-2075.1992.Tb05435.X  0.343
1992 Meininger CJ, Yano H, Rottapel R, Bernstein A, Zsebo KM, Zetter BR. The c-kit receptor ligand functions as a mast cell chemoattractant Blood. 79: 958-963. PMID 1371080 DOI: 10.1182/Blood.V79.4.958.958  0.625
1991 Reith AD, Bernstein A. Molecular basis of mouse developmental mutants. Genes & Development. 5: 1115-1123. PMID 2065969 DOI: 10.1101/Gad.5.7.1115  0.32
1991 Ben-David Y, Giddens EB, Letwin K, Bernstein A. Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. Genes & Development. 5: 908-18. PMID 2044959 DOI: 10.1101/Gad.5.6.908  0.327
1991 Pawson T, Bernstein A. Receptor tyrosine kinases: genetic evidence for their role in Drosophila and mouse development. Trends in Genetics : Tig. 6: 350-6. PMID 1965067 DOI: 10.1016/0168-9525(90)90276-C  0.351
1991 Forrester LM, Bernstein A, Rossant J, Nagy A. Long-term reconstitution of the mouse hematopoietic system by embryonic stem cell-derived fetal liver. Proceedings of the National Academy of Sciences of the United States of America. 88: 7514-7. PMID 1881890 DOI: 10.1073/Pnas.88.17.7514  0.376
1991 Dubreuil P, Forrester L, Rottapel R, Reedijk M, Fujita J, Bernstein A. The c-fms gene complements the mitogenic defect in mast cells derived from mutant W mice but not mi (microphthalmia) mice. Proceedings of the National Academy of Sciences of the United States of America. 88: 2341-5. PMID 1826051 DOI: 10.1073/Pnas.88.6.2341  0.71
1991 Rottapel R, Reedijk M, Williams DE, Lyman SD, Anderson DM, Pawson T, Bernstein A. The Steel/W Transduction Pathway: Kit Autophosphorylation and Its Association with a Unique Subset of Cytoplasmic Signaling Proteins Is Induced by the Steel Factor Molecular and Cellular Biology. 11: 3043-3051. PMID 1710023 DOI: 10.1128/Mcb.11.6.3043  0.621
1991 Olivieri N, Grunberger T, Ben-David Y, Ng J, Williams D, Lyman S, Anderson D, Axelrad A, Correa P, Bernstein A. Diamond-Blackfan anemia: heterogenous response of hematopoietic progenitor cells in vitro to the protein product of the steel locus. Blood. 78: 2211-2215. DOI: 10.1182/Blood.V78.9.2211.Bloodjournal7892211  0.345
1991 Ben-David Y, Letwin K, Tannock L, Bernstein A, Pawson T. A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators. The Embo Journal. 10: 317-325. DOI: 10.1002/J.1460-2075.1991.Tb07952.X  0.322
1990 Ben-David Y, Giddens EB, Bernstein A. Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus. Proceedings of the National Academy of Sciences of the United States of America. 87: 1332-6. PMID 2304901 DOI: 10.1073/Pnas.87.4.1332  0.365
1990 Breitman ML, Rombola H, Maxwell IH, Klintworth GK, Bernstein A. Genetic ablation in transgenic mice with an attenuated diphtheria toxin A gene. Molecular and Cellular Biology. 10: 474-9. PMID 2300048 DOI: 10.1128/Mcb.10.2.474  0.394
1990 Greer P, Maltby V, Rossant J, Bernstein A, Pawson T. Myeloid expression of the human c-fps/fes proto-oncogene in transgenic mice. Molecular and Cellular Biology. 10: 2521-7. PMID 2188092 DOI: 10.1128/Mcb.10.6.2521  0.322
1990 Steeg CM, Ellis J, Bernstein A. Introduction of specific point mutations into RNA polymerase II by gene targeting in mouse embryonic stem cells: evidence for a DNA mismatch repair mechanism. Proceedings of the National Academy of Sciences of the United States of America. 87: 4680-4. PMID 1972278 DOI: 10.1073/Pnas.87.12.4680  0.371
1990 Dubreuil P, Rottapel R, Reith AD, Forrester L, Bernstein A. The mouse W/c-kit locus. A mammalian gene that controls the development of three distinct cell lineages. Annals of the New York Academy of Sciences. 599: 58-65. PMID 1699461 DOI: 10.1111/J.1749-6632.1990.Tb42364.X  0.707
1990 Reith AD, Rottapel R, Giddens E, Brady C, Forrester L, Bernstein A. W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor. Genes & Development. 4: 390-400. PMID 1692559 DOI: 10.1101/Gad.4.3.390  0.623
1989 Korczak B, Robson IB, Lamarche C, Bernstein A, Kerbel RS. Genetic tagging of tumor cells with retrovirus vectors: clonal analysis of tumor growth and metastasis in vivo. Molecular and Cellular Biology. 8: 3143-9. PMID 3211140 DOI: 10.1128/Mcb.8.8.3143  0.317
1989 Ellis J, Bernstein A. Gene targeting with retroviral vectors: recombination by gene conversion into regions of nonhomology. Molecular and Cellular Biology. 9: 1621-7. PMID 2725520 DOI: 10.1128/Mcb.9.4.1621  0.375
1989 Yee SP, Mock D, Greer P, Maltby V, Rossant J, Bernstein A, Pawson T. Lymphoid and mesenchymal tumors in transgenic mice expressing the v-fps protein-tyrosine kinase. Molecular and Cellular Biology. 9: 5491-9. PMID 2555699 DOI: 10.1128/Mcb.9.12.5491  0.362
1989 Lavigueur A, Maltby V, Mock D, Rossant J, Pawson T, Bernstein A. High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene. Molecular and Cellular Biology. 9: 3982-3991. PMID 2476668 DOI: 10.1128/Mcb.9.9.3982  0.334
1989 Nocka K, Majumder S, Chabot B, Ray P, Cervone M, Bernstein A, Besmer P. Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice. Genes & Development. 3: 816-26. PMID 2473008 DOI: 10.1101/Gad.3.6.816  0.405
1988 Chabot B, Stephenson DA, Chapman VM, Besmer P, Bernstein A. The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature. 335: 88-9. PMID 2457811 DOI: 10.1038/335088A0  0.414
1987 Breitman ML, Clapoff S, Rossant J, Tsui LC, Glode LM, Maxwell IH, Bernstein A. Genetic ablation: targeted expression of a toxin gene causes microphthalmia in transgenic mice. Science (New York, N.Y.). 238: 1563-5. PMID 3685993 DOI: 10.1126/Science.3685993  0.385
1987 Rovinski B, Munroe D, Peacock J, Mowat M, Bernstein A, Benchimol S. Deletion of 5'-coding sequences of the cellular p53 gene in mouse erythroleukemia: a novel mechanism of oncogene regulation. Molecular and Cellular Biology. 7: 847-53. PMID 3547084 DOI: 10.1128/Mcb.7.2.847  0.358
1987 Wu DD, Huszar D, Dick JE, Bernstein A, Phillips RA. High efficiency gene transfer and expression in normal murine B lymphocytes. Journal of Immunological Methods. 101: 279-85. PMID 3302049 DOI: 10.1016/0022-1759(87)90161-X  0.358
1987 Magli MC, Dick JE, Huszar D, Bernstein A, Phillips RA. Modulation of gene expression in multiple hematopoietic cell lineages following retroviral vector gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 84: 789-93. PMID 3027704 DOI: 10.1073/Pnas.84.3.789  0.413
1987 Chow V, Ben-David Y, Bernstein A, Benchimol S, Mowat M. Multistage Friend erythroleukemia: independent origin of tumor clones with normal or rearranged p53 cellular oncogenes. Journal of Virology. 61: 2777-2781. DOI: 10.1128/Jvi.61.9.2777-2781.1987  0.399
1986 Schiff RD, Oliff A, Bernstein A. The pathophysiology of murine retrovirus-induced leukemias. Critical Reviews in Oncology Hematology. 5: 257-323. PMID 3527464 DOI: 10.1016/S1040-8428(86)80041-5  0.358
1986 Belmont JW, Henkel-Tigges J, Chang SM, Wager-Smith K, Kellems RE, Dick JE, Magli MC, Phillips RA, Bernstein A, Caskey CT. Expression of human adenosine deaminase in murine haematopoietic progenitor cells following retroviral transfer. Nature. 322: 385-7. PMID 3016551 DOI: 10.1038/322385A0  0.365
1986 Mager DL, Bernstein A. Induction of clonogenic and erythroleukemic cells by different helper virus pseudotypes of Friend spleen focus-forming virus. Virology. 141: 337-41. PMID 3002024 DOI: 10.1016/0042-6822(85)90269-7  0.353
1986 Dick JE, Magli MC, Phillips RA, Bernstein A. Genetic manipulation of hematopoietic stem cells with retrovirus vectors Trends in Genetics. 2: 165-170. DOI: 10.1016/0168-9525(86)90212-X  0.344
1985 Dick JE, Magli MC, Huszar D, Phillips RA, Bernstein A. Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/Wv mice Cell. 42: 71-79. PMID 4016956 DOI: 10.1016/S0092-8674(85)80102-1  0.411
1985 Mowat M, Cheng A, Kimura N, Bernstein A, Benchimol S. Rearrangements of the cellular p53 gene in erythroleukaemic cells transformed by Friend virus Nature. 314: 633-636. PMID 3990796 DOI: 10.1038/314633A0  0.354
1985 Robson IB, Mowat M, Bernstein A. Tissue-specific expression of the newly acquired ecotropic Emv-18 provirus in Fv-2 congenic mice. Journal of Virology. 55: 54-9. PMID 3874291 DOI: 10.1128/Jvi.55.1.54-59.1985  0.311
1985 Berger SA, Sanderson N, Bernstein A, Hankins WD. Induction of the early stages of Friend erythroleukemia with helper-free Friend spleen focus-forming virus. Proceedings of the National Academy of Sciences of the United States of America. 82: 6913-7. PMID 2995992 DOI: 10.1073/Pnas.82.20.6913  0.326
1985 Rubin JS, Prideaux VR, Willard HF, Dulhanty AM, Whitmore GF, Bernstein A. Molecular cloning and chromosomal localization of DNA sequences associated with a human DNA repair gene Molecular and Cellular Biology. 5: 398-405. PMID 2983193 DOI: 10.1128/mcb.5.2.398-405.1985  0.302
1985 Huszar D, Balling R, Kothary R, Magli MC, Hozumi N, Rossant J, Bernstein A. Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector. Proceedings of the National Academy of Sciences of the United States of America. 82: 8587-91. PMID 2417225 DOI: 10.1073/Pnas.82.24.8587  0.383
1983 Rubin JS, Joyner AL, Bernstein A, Whitmore GF. Molecular identification of a human DNA repair gene following DNA-mediated gene transfer. Nature. 306: 206-8. PMID 6417541 DOI: 10.1038/306206A0  0.509
1983 Joyner AL, Bernstein A. Retrovirus transduction: segregation of the viral transforming function and the herpes simplex virus tk gene in infectious Friend spleen focus-forming virus thymidine kinase vectors. Molecular and Cellular Biology. 3: 2191-202. PMID 6318088  0.5
1983 Joyner AL, Bernstein A. Retrovirus transduction: generation of infectious retroviruses expressing dominant and selectable genes is associated with in vivo recombination and deletion events. Molecular and Cellular Biology. 3: 2180-90. PMID 6318087  0.522
1983 Joyner A, Keller G, Phillips RA, Bernstein A. Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells. Nature. 305: 556-8. PMID 6312324 DOI: 10.1038/305556A0  0.597
1982 Joyner A, Yamamoto Y, Bernstein A. Retrovirus long terminal repeats activate expression of coding sequences for the herpes simplex virus thymidine kinase gene. Proceedings of the National Academy of Sciences of the United States of America. 79: 1573-7. PMID 6280191  0.511
1981 Mager D, MacDonald ME, Robson IB, Mak TW, Bernstein A. Clonal analysis of the late stages of erythroleukemia induced by two distinct strains of Friend leukemia virus. Molecular and Cellular Biology. 1: 721-30. PMID 9279385 DOI: 10.1128/Mcb.1.8.721  0.352
1981 Mager DL, Mak TW, Bernstein A. Quantitative colony method for tumorigenic cells transformed by two distinct strains of Friend leukemia virus. Proceedings of the National Academy of Sciences of the United States of America. 78: 1703-7. PMID 6940184 DOI: 10.1073/Pnas.78.3.1703  0.366
1981 Mager D, Bernstein A. Phorbol ester tumor promoters block the transition from the early to the heme-dependent late program of Friend cell differentiation. Journal of Cellular Physiology. 105: 519-26. PMID 6936401 DOI: 10.1002/Jcp.1041050316  0.322
1981 Mager D, Mak TW, Bernstein A. Friend leukaemia virus-transformed cells, unlike normal stem cells, form spleen colonies in Sl/sld mice. Nature. 288: 592-4. PMID 6934375 DOI: 10.1038/288592A0  0.635
1981 Yamamoto Y, Gamble CL, Clark SP, Joyner A, Shibuya T, MacDonald ME, Mager D, Bernstein A, Mak TW. Clonal analysis of early and late stages of erythroleukemia induced by molecular clones of integrated spleen focus-forming virus. Proceedings of the National Academy of Sciences of the United States of America. 78: 6893-7. PMID 6273894 DOI: 10.1073/Pnas.78.11.6893  0.67
1981 MacDonald ME, Johnson GR, Bernstein A. Different pseudotypes of Friend spleen focus-forming virus induce polycythemia and erythropoietin-independent colony formation in serum-free medium. Virology. 110: 231-6. PMID 6259832 DOI: 10.1016/0042-6822(81)90028-3  0.335
1980 Crichley V, Mager D, Bernstein A. Colchicine resistant Friend cells: application to the study of actinomycin D induced erythroid differentiation. Journal of Cellular Physiology. 102: 63-70. PMID 6929276 DOI: 10.1002/Jcp.1041020110  0.334
1980 Mak TW, Axelrad AA, Bernstein A. Fv-2 locus controls expression of Friend spleen focus-forming virus-specific sequences in normal and infected mice. Proceedings of the National Academy of Sciences of the United States of America. 76: 5809-12. PMID 293685 DOI: 10.1073/Pnas.76.11.5809  0.345
1979 Mager D, Bernstein A. The role of heme in the regulation of the late program of Friend cell erythroid differentiation. Journal of Cellular Physiology. 100: 467-79. PMID 489671 DOI: 10.1002/Jcp.1041000310  0.35
1979 Bernstein A, Gamble C, Penrose D, Mak TW. Presence and expression of Friend erythroleukemia virus-related sequences in normal and leukemic mouse tissues. Proceedings of the National Academy of Sciences of the United States of America. 76: 4455-9. PMID 291976 DOI: 10.1073/Pnas.76.9.4455  0.363
1979 Mager D, Bernstein A. The program of Friend cell erythroid differentiation: early changes in Na+/K+ ATPase function. Journal of Supramolecular Structure. 8: 431-8. PMID 214640 DOI: 10.1002/Jss.400080405  0.302
1977 Bernstein A, Mak TW, Stephenson JR. The Friend virus genome: evidence for the stable association of MuLV sequences and sequences involved in erythroleukemic transformation. Cell. 12: 287-94. PMID 902316 DOI: 10.1016/0092-8674(77)90206-9  0.347
1977 Loritz F, Bernstein A, Miller RG. Early and late volume changes during erythroid differentiation of cultured Friend leukemic cells. Journal of Cellular Physiology. 90: 423-37. PMID 265944 DOI: 10.1002/Jcp.1040900306  0.323
1976 Collins JJ, Destree AT, Marshall CJ, Bernstein A, Macpherson IA. Chromosomally depleted interspecific hybrid cell clones selected with cytotoxic antisera: utilization in the study of control of murine leukemia virus host-range. Journal of Supramolecular Structure. 4: 71-88. PMID 176536 DOI: 10.1002/Jss.400040108  0.333
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