Heather E. Fleming, Ph.D. - Publications

Affiliations: 
2003 University of Toronto, Toronto, ON, Canada 
Area:
Immunology, Molecular Biology

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, Côté D, Rowe DW, Lin CP, Scadden DT. Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature. 457: 92-6. PMID 19052546 DOI: 10.1038/Nature07434  0.372
2008 Janzen V, Fleming HE, Riedt T, Karlsson G, Riese MJ, Lo Celso C, Reynolds G, Milne CD, Paige CJ, Karlsson S, Woo M, Scadden DT. Hematopoietic stem cell responsiveness to exogenous signals is limited by caspase-3. Cell Stem Cell. 2: 584-94. PMID 18522851 DOI: 10.1016/J.Stem.2008.03.012  0.632
2008 Fleming HE, Janzen V, Lo Celso C, Guo J, Leahy KM, Kronenberg HM, Scadden DT. Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo. Cell Stem Cell. 2: 274-83. PMID 18371452 DOI: 10.1016/J.Stem.2008.01.003  0.426
2006 Janzen V, Forkert R, Fleming HE, Saito Y, Waring MT, Dombkowski DM, Cheng T, DePinho RA, Sharpless NE, Scadden DT. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature. 443: 421-6. PMID 16957735 DOI: 10.1038/Nature05159  0.319
2006 Fleming HE, Scadden DT. Embryonic stem cells make human T cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 12213-4. PMID 16894150 DOI: 10.1073/Pnas.0605344103  0.418
2006 Janzen V, Fleming HE, Waring MT, Milne CD, Scadden DT. Multifunctional Role of Caspase-3 in Regulating Hematopoietic Stem Cells. Blood. 108: 861-861. DOI: 10.1182/Blood.V108.11.861.861  0.445
2005 Janzen V, Fleming H, Reynolds G, Waring M, Scadden DT. Caspase-3 Has Apoptotic and Non-Apoptotic Functions in Regulating the Fate of Hematopoietic Stem Cells. Blood. 106: 1717-1717. DOI: 10.1182/Blood.V106.11.1717.1717  0.4
2004 Milne CD, Fleming HE, Paige CJ. IL-7 does not prevent pro-B/pre-B cell maturation to the immature/sIgM(+) stage. European Journal of Immunology. 34: 2647-55. PMID 15368280 DOI: 10.1002/Eji.200425400  0.707
2004 Fleming HE, Milne CD, Paige CJ. CD45-deficient mice accumulate Pro-B cells both in vivo and in vitro. Journal of Immunology (Baltimore, Md. : 1950). 173: 2542-51. PMID 15294970 DOI: 10.4049/Jimmunol.173.4.2542  0.714
2004 Milne CD, Fleming HE, Zhang Y, Paige CJ. Mechanisms of selection mediated by interleukin-7, the preBCR, and hemokinin-1 during B-cell development. Immunological Reviews. 197: 75-88. PMID 14962188 DOI: 10.1111/J.0105-2896.2004.0103.X  0.763
2002 Fleming HE, Paige CJ. Cooperation between IL-7 and the pre-B cell receptor: a key to B cell selection. Seminars in Immunology. 14: 423-30. PMID 12457615 DOI: 10.1016/S1044532302000775  0.742
2002 Velazquez L, Cheng AM, Fleming HE, Furlonger C, Vesely S, Bernstein A, Paige CJ, Pawson T. Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice. The Journal of Experimental Medicine. 195: 1599-611. PMID 12070287 DOI: 10.1084/Jem.20011883  0.66
2001 Fleming HE, Paige CJ. Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway. Immunity. 15: 521-31. PMID 11672535 DOI: 10.1016/S1074-7613(01)00216-3  0.735
2001 Stoddart A, Fleming HE, Paige CJ. The role of homotypic interactions in the differentiation of B cell precursors. European Journal of Immunology. 31: 1160-72. PMID 11298341 DOI: 10.1002/1521-4141(200104)31:4<1160::Aid-Immu1160>3.0.Co;2-T  0.716
2000 Stoddart A, Fleming HE, Paige CJ. The role of the preBCR, the interleukin-7 receptor, and homotypic interactions during B-cell development. Immunological Reviews. 175: 47-58. PMID 10933590 DOI: 10.1111/J.1600-065X.2000.Imr017511.X  0.762
1998 Marshall AJ, Fleming HE, Wu GE, Paige CJ. Modulation of the IL-7 dose-response threshold during pro-B cell differentiation is dependent on pre-B cell receptor expression. Journal of Immunology (Baltimore, Md. : 1950). 161: 6038-45. PMID 9834086  0.7
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