We are testing a new system for linking grants to scientists.
The funding information displayed below comes from the
NIH Research Portfolio Online Reporting Tools and the
NSF Award Database.
The grant data on this page is limited to grants awarded in the United States and is thus partial. It can nonetheless be used to understand how funding patterns influence mentorship networks and vice-versa, which has deep implications on how research is done.
You can help! If you notice any innacuracies, please
sign in and mark grants as correct or incorrect matches.
Sign in to see low-probability grants and correct any errors in linkage between grants and researchers.
High-probability grants
According to our matching algorithm, Abdallah Hayar is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
2004 — 2006 |
Hayar, Abdallah M |
R03Activity Code Description: To provide research support specifically limited in time and amount for studies in categorical program areas. Small grants provide flexibility for initiating studies which are generally for preliminary short-term projects and are non-renewable. |
Synchronous Bursting Among Juxtaglomerular Neurons @ University of Tennessee Health Sci Ctr
DESCRIPTION (provided by applicant): Oscillations, bursting, and resonance have been linked to synchronization of neuronal activity and to the emergence of brain rhythms. Using simultaneous whole-cell recording from pairs of juxtaglomerular (JG) olfactory bulb neurons, we were the first to discover that membrane potential oscillations and spontaneous bursting activity are highly correlated in external tufted (ET) cells associated with the same glomeruli. This synchronous activity occurs at theta frequency (2-7 Hz), the same frequency that characterizes investigative sniffing in rodents. Synchronous ET cell bursting may play an important role in olfactory coding and in regulating the induction of synaptic plasticity at the first input stage of the main olfactory bulb. We have further found that synchronous activity among bursting neurons persists in the presence of blockers of fast glutamatergic and GABAergic synaptic transmission. These findings suggest that synchrony could be mediated by slowly acting neurotransmitters and/or by non-synaptic interactions such as gap junctions that interconnect ET cells. Synchronously active ET cells could, in turn, via synaptic interactions synchronize other JG neurons, as well as mitral cells, the major output neurons of the olfactory bulb. This project will assess the functional roles of synaptic and non-synaptic interactions in establishing synchronous activity among electrophysiologically and morphologically characterized JG neurons. Further, it will investigate the functional significance of synchronous bursting by analyzing short-term facilitation of excitatory postsynaptic potentials that are evoked by ET cell bursts in periglomerular and short axon cells of the same glomerulus. This would support the idea that glomerular interneurons that are postsynaptic to ET cells, may act as coincident input detectors, firing optimally upon receiving synchronous bursting input. Taken together, these experiments will provide important, new insight into the intrinsic synaptic organization of the glomeruli and the role of glomerular circuitry in olfactory coding.
|
0.958 |
2005 — 2009 |
Hayar, Abdallah M |
R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. |
External Tufted Cells Coordinate Olfactory Bulb Activity @ University of Arkansas Med Scis Ltl Rock
DESCRIPTION (provided by applicant): Oscillations or cycling discharges of neurons provide a clock or impose a "tempo" for various kinds of information processing. We recently found that olfactory bulb ET cells are endowed with spontaneous rhythmic bursting that persists and becomes more regular in the presence of fast synaptic blockers. Using simultaneous whole-cell recording from pairs of juxtaglomerular (JG) neurons, we were the first to discover that membrane potential oscillations and spontaneous bursting activity are highly correlated in external tufted (ET) cells associated with the same glomeruli. This synchronous activity occurs at theta frequency (1-8 Hz), the same frequency that characterizes investigative sniffing in rodents. Therefore, synchronous ET cell bursting may play an important role in olfactory coding and in regulating the induction of synaptic plasticity at the first input stage of the main olfactory bulb. In this proposal, we hypothesize that ET cells coordinate the activity of other olfactory bulb neurons and may play a role of a pattern generator of the olfactory bulb network. In particular, this project will assess the functional roles of synaptic and non-synaptic interactions in establishing correlated activity between ET cells and other neurons including interneurons and output neurons. We will use dual patch clamp and extracellular recording techniques and cross-correlation analysis to test the following hypotheses: (i) ET cell bursting activity is shaped by feedback dendrodendritic inhibition from PG cells, (ii) ET cells in neighboring glomeruli have correlated activity that is mediated by short axon cells, (iii) ET cells coordinate the activity of other output neurons, tufted and mitral cells, via chemical and electrical synapses. Taken together, the experiments proposed in this study will provide important, new insights into the intrinsic synaptic organization of the glomeruli and the role of glomerular circuitry in olfactory coding.
|
0.958 |