Philippe P. Roux, Ph.D.
Affiliations: | 1997-2002 | Neurology and Neurosurgery | McGill (Montreal Neurological Institute) |
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"Philippe Roux"Mean distance: 14.18 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Phil Barker | grad student | 1997-2002 | McGill | |
| (Signaling pathways implicated in p75 neurotrophin receptor -mediated neuronal survival and death.) | ||||
| Timothy E. Kennedy | grad student | 1997-2002 | McGill University (Montreal Neurological Institute) | |
| John Blenis | post-doc | 2002-2006 | Harvard Medical School | |
Children
Sign in to add trainee| Sami Nourreddine | grad student | 2016-2021 | University of Montreal (Canada) |
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Publications
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| Houles T, Yoon SO, Roux PP. (2024) The expanding landscape of canonical and non-canonical protein phosphorylation. Trends in Biochemical Sciences |
| Lizcano-Perret B, Vertommen D, Herinckx G, et al. (2024) Identification of RSK substrates using an analog-sensitive kinase approach. The Journal of Biological Chemistry. 105739 |
| Houles T, Lavoie G, Nourreddine S, et al. (2022) CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. Nature Communications. 13: 6457 |
| Vadnjal N, Nourreddine S, Lavoie G, et al. (2022) Proteomic analysis of the actin cortex in interphase and mitosis. Journal of Cell Science |
| Tee AR, Manning BD, Roux PP, et al. (2022) Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb. Current Biology : Cb. 32: 733-734 |
| Cerezo EL, Houles T, Lié O, et al. (2021) RIOK2 phosphorylation by RSK promotes synthesis of the human small ribosomal subunit. Plos Genetics. 17: e1009583 |
| Méant A, Gao B, Lavoie G, et al. (2020) Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion. Molecular & Cellular Proteomics : McP. 19: 50-64 |
| De Jamblinne CV, Decelle B, Dehghani M, et al. (2020) STRIPAK regulates Slik localization to control mitotic morphogenesis and epithelial integrity. The Journal of Cell Biology. 219 |
| Aubert L, Nandagopal N, Steinhart Z, et al. (2020) Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer. Nature Communications. 11: 3701 |
| Nourreddine S, Lavoie G, Paradis J, et al. (2020) NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay. Cell Reports. 31: 107660 |