David E. Lenz
Affiliations: | 2004- | Physiology | U.S. Army Medical Research Institute of Chemical Defense |
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Sign in to add trainee| David T. Yeung | grad student | 2004-2007 | U.S. Army Medical Research Institute of Chemical Defense |
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Publications
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| Cerasoli DM, Armstrong SJ, Reeves TE, et al. (2019) Butyrylcholinesterase, a stereospecific in vivo bioscavenger against nerve agent intoxication. Biochemical Pharmacology. 113670 |
| Lenz DE, Cerasoli D, Maxwell DM. (2017) Radiolabelled Soman Binding to Sera from Rats, Guinea Pigs and Monkeys. Toxicology Letters |
| Reed BA, Sabourin CL, Lenz DE. (2017) Human butyrylcholinesterase efficacy against nerve agent exposure. Journal of Biochemical and Molecular Toxicology |
| Sarkar M, Harsch CK, Matic GT, et al. (2012) Solubilization and humanization of paraoxonase-1. Journal of Lipids. 2012: 610937 |
| Mumford H, E Price M, Lenz DE, et al. (2011) Post-exposure therapy with human butyrylcholinesterase following percutaneous VX challenge in guinea pigs. Clinical Toxicology (Philadelphia, Pa.). 49: 287-97 |
| Sanan TT, Muthukrishnan S, Beck JM, et al. (2010) Computational Modeling of Human Paraoxonase 1: Preparation of Protein Models, Binding Studies, and Mechanistic Insights. Journal of Physical Organic Chemistry. 23: 357-369 |
| Geyer BC, Kannan L, Garnaud PE, et al. (2010) Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents. Proceedings of the National Academy of Sciences of the United States of America. 107: 20251-6 |
| Lenz DE, Clarkson ED, Schulz SM, et al. (2010) Butyrylcholinesterase as a therapeutic drug for protection against percutaneous VX. Chemico-Biological Interactions. 187: 249-52 |
| Cadieux CL, Broomfield CA, Kirkpatrick MG, et al. (2010) Comparison of human and guinea pig acetylcholinesterase sequences and rates of oxime-assisted reactivation. Chemico-Biological Interactions. 187: 229-33 |
| Suzuki SM, Stevens RC, Richter RJ, et al. (2010) Engineering human PON1 in an E. coli expression system. Advances in Experimental Medicine and Biology. 660: 37-45 |