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Joseph C. McNulty, Ph.D.

Affiliations: 
University of California, Santa Cruz, Santa Cruz, CA, United States 
Area:
biophysical methods to study neurological proteins, their cofactors and how misregulation contributes to disease
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"Joseph McNulty"
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Glenn L. Millhauser grad student 2002 UC Santa Cruz
 (Synthesis of peptides and their study by magnetic resonance: New spin labels and novel protein structures.)

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Publications

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Abdel-Malek ZA, Kadekaro AL, Kavanagh RJ, et al. (2006) Melanoma prevention strategy based on using tetrapeptide alpha-MSH analogs that protect human melanocytes from UV-induced DNA damage and cytotoxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1561-3
McNulty JC, Jackson PJ, Thompson DA, et al. (2005) Structures of the agouti signaling protein. Journal of Molecular Biology. 346: 1059-70
Millhauser GL, McNulty JC, Jackson PJ, et al. (2003) Loops and links: structural insights into the remarkable function of the agouti-related protein. Annals of the New York Academy of Sciences. 994: 27-35
McNulty JC, Thompson DA, Carrasco MR, et al. (2002) Dap-SL: A new site-directed nitroxide spin labeling approach for determining structure and motions in synthesized peptides and proteins Febs Letters. 529: 243-248
Jackson PJ, McNulty JC, Yang YK, et al. (2002) Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity. Biochemistry. 41: 7565-72
McNulty JC, Thompson DA, Bolin KA, et al. (2001) High-resolution NMR structure of the chemically-synthesized melanocortin receptor binding domain AGRP(87-132) of the agouti-related protein. Biochemistry. 40: 15520-7
McNulty JC, Silapie JL, Carnevali M, et al. (2000) Electron spin resonance of TOAC labeled peptides: Folding transitions and high frequency spectroscopy Biopolymers - Peptide Science Section. 55: 479-485
Anderson DJ, Hanson P, McNulty J, et al. (1999) Solution structures of TOAC-labeled trichogin GA IV peptides from allowed (g κ 2) and half-field electron spin resonance Journal of the American Chemical Society. 121: 6919-6927
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