Matthew D. Hirschey, Ph.D.

Affiliations: 
University of California, Santa Barbara, Santa Barbara, CA, United States 
Area:
bioinorganic chemistry and metallobiochemistry
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Alison Butler grad student 2006 UC Santa Barbara
 (Monitoring bacterial processes using CdSe/CdS core/shell quantum dots.)
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Publications

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Bhatt DP, Mills CA, Anderson KA, et al. (2022) Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice. The Journal of Biological Chemistry. 101723
Gonzalez-Hunt CP, Luz AL, Ryde IT, et al. (2020) Multiple metabolic changes mediate the response of Caenorhabditis elegans to the complex I inhibitor rotenone. Toxicology. 152630
Naiman S, Huynh FK, Gil R, et al. (2019) SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα. Cell Reports. 29: 4127-4143.e8
Assiri MA, Ali HR, Marentette JO, et al. (2019) Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease. Human Genomics. 13: 65
Ali HR, Assiri MA, Harris PS, et al. (2019) Quantifying competition among mitochondrial protein acylation events induced by ethanol metabolism. Journal of Proteome Research
Mills CA, Trub AG, Hirschey MD. (2018) Sensing Mitochondrial Acetyl-CoA to Tune Respiration. Trends in Endocrinology and Metabolism: Tem
Peterson BS, Campbell JE, Ilkayeva O, et al. (2018) Remodeling of the Acetylproteome by SIRT3 Manipulation Fails to Affect Insulin Secretion or β Cell Metabolism in the Absence of Overnutrition. Cell Reports. 24: 209-223.e6
Hershberger KA, Abraham DM, Liu J, et al. (2018) Ablation of Sirtuin5 in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload. The Journal of Biological Chemistry
Trub AG, Hirschey MD. (2018) Reactive Acyl-CoA Species Modify Proteins and Induce Carbon Stress. Trends in Biochemical Sciences
Hu Y, Semova I, Sun X, et al. (2017) Fructose and glucose regulate mammalian target of rapamycin complex 1 and can activate lipogenic gene expression via distinct pathways. The Journal of Biological Chemistry
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