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Lucy E. O'Brien, Ph.D.

Affiliations: 
University of California, San Francisco, San Francisco, CA 
 2013- Molecular and Cellular Physiology Stanford University School of Medicine, Palo Alto, CA, United States 
Area:
cell polarity
Website:
https://med.stanford.edu/profiles/lucy-obrien
Google:
"Lucy O'Brien"
Bio:

http://www.stemdynamics.org/people.html

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Parents

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Keith E. Mostov grad student 2001 UCSF
 (Regulatory forces during three-dimensional epithelial morphogenesis.)
David Bilder post-doc 2005-2009 UC Berkeley

Children

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XinXin Du post-doc Stanford (Chemistry Tree)

Collaborators

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Publications

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Galenza A, Moreno-Roman P, Su YH, et al. (2023) Basal stem cell progeny establish their apical surface in a junctional niche during turnover of an adult barrier epithelium. Nature Cell Biology
Kim AA, Nguyen A, Marchetti M, et al. (2022) Independently paced calcium oscillations in progenitor and differentiated cells in an ex vivo epithelial organ. Journal of Cell Science
Li H, Janssens J, De Waegeneer M, et al. (2022) Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly. Science (New York, N.Y.). 375: eabk2432
Martin JL, Sanders EN, Moreno-Roman P, et al. (2018) Long-term live imaging of the adult midgut reveals real-time dynamics of division, differentiation, and loss. Elife. 7
Martin JL, Sanders EN, Moreno-Roman P, et al. (2018) Author response: Long-term live imaging of the Drosophila adult midgut reveals real-time dynamics of division, differentiation and loss Elife
Liang J, Balachandra S, Ngo S, et al. (2017) Feedback regulation of steady-state epithelial turnover and organ size. Nature
Du X, O'Brien LE, Riedel-Kruse IH. (2017) A Model for Adult Organ Resizing Demonstrates Stem Cell Scaling through a Tunable Commitment Rate. Biophysical Journal. 113: 174-184
O'Brien LE, Bilder D. (2013) Beyond the niche: tissue-level coordination of stem cell dynamics. Annual Review of Cell and Developmental Biology. 29: 107-36
O'Brien LE, Soliman SS, Li X, et al. (2011) Altered modes of stem cell division drive adaptive intestinal growth. Cell. 147: 603-14
Kim M, O'Brien LE, Kwon SH, et al. (2010) STAT1 is required for redifferentiation during Madin-Darby canine kidney tubulogenesis. Molecular Biology of the Cell. 21: 3926-33
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