Philippe Huot, Ph.D.

Affiliations: 
Medical Science University of Toronto, Toronto, ON, Canada 
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"Philippe Huot"
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Robert Chen grad student 2012 University of Toronto
 (Serotonin- and dopamine-mediated neurotransmission in the pathophysiology and treatment of Parkinson's disease.)
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Publications

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Kang W, Frouni I, Kwan C, et al. (2024) Activation of mGlu 2/3 receptors with the orthosteric agonist LY-404,039 alleviates dyskinesia in experimental parkinsonism. Behavioural Pharmacology
Frouni I, Kwan C, Bédard D, et al. (2023) Effect of the mGlu positive allosteric modulator ADX-88178 on parkinsonism, psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset. Psychopharmacology
Kwan C, Frouni I, Bédard D, et al. (2023) The 5-HT inverse agonist nelotanserin alleviates L-DOPA-induced dyskinesia in the MPTP-lesioned marmoset. The European Journal of Neuroscience
Kang W, Nuara SG, Bédard D, et al. (2023) The mGluR orthosteric agonist LY-404,039 reduces dyskinesia, psychosis-like behaviours and parkinsonism in the MPTP-lesioned marmoset. Naunyn-Schmiedeberg's Archives of Pharmacology
Al-Kassmy J, Sun C, Huot P. (2023) 5-HT agonists for levodopa-induced dyskinesia in Parkinson's disease. Neurodegenerative Disease Management. 13: 101-112
Kwan C, Kang W, Kim E, et al. (2022) Metabotropic glutamate receptors in Parkinson's disease. International Review of Neurobiology. 168: 1-31
Frouni I, Kwan C, Belliveau S, et al. (2022) Anti-parkinsonian effect of the mGlu positive allosteric modulator LY-487,379 as monotherapy and adjunct to a low L-DOPA dose in the MPTP-lesioned marmoset. European Journal of Pharmacology. 939: 175429
Frouni I, Kang W, Bédard D, et al. (2022) Effect of glycine transporter 1 inhibition with bitopertin on parkinsonism and L-DOPA induced dyskinesia in the 6-OHDA-lesioned rat. European Journal of Pharmacology. 175090
Kwan C, Lévesque C, Bédard D, et al. (2021) Autoradiographic labelling of 5-HT receptors in the hemi-parkinsonian rat brain. Neuroscience Research
Nuara SG, Gourdon JC, Maddaford S, et al. (2021) Additive effects of mGluR positive allosteric modulation, mGluR orthosteric stimulation and 5-HTR antagonism on dyskinesia and psychosis-like behaviours in the MPTP-lesioned marmoset. Naunyn-Schmiedeberg's Archives of Pharmacology
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