A Claudio Cuello, OC, MD, DSc, FRSC, FMedSci, FMedSci
Affiliations: | 1985- | Pharmacology And Therapeutics | McGill University, Montreal, QC, Canada |
Area:
Alzheimer's Disease, cognitive behavior, neurochemistry, immunocytochemistry, neuropharmacology and molecular biology.Google:
"A Claudio Cuello"Bio:
Since 2003, he has been the Charles E. Frosst/Merck endowed Chair in Pharmacology at McGill University. He leads a research team on multidisciplinary aspects (cognitive behavior, neurochemistry, immunocytochemistry, neuropharmacology and molecular biology) of brain aging and Alzheimer’s disease neuropathology. The Cuello Lab is comprised of talented and motivated colleagues focused on unravelling the earliest biochemical-pathological events of the Alzheimer’s pathology as well as searching for early biomarkers and novel experimental therapies to arrest or revert the early Alzheimer’s pathology. His group has recently made important contributions to the understanding of CNS trophic factor deregulation both in Alzheimer’s disease and in Down syndrome.
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Mean distance: 13.39 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Amanda Pellegrino de Iraldi | grad student | Universidad de Buenos Aires | |
| Eduardo De Robertis | grad student | UBA | |
| William Francis Ganong | post-doc | UCSF (Physiology Academic Tree) | |
| Leslie Iversen | post-doc | Cambridge | |
| Fernando Orioli | post-doc | Universidad de Buenos Aires | |
| Umberto Tramezzani | post-doc | IBYME-CONICET Buenos Aires |
Children
Sign in to add trainee| Lisi Flores Aguilar | grad student | McGill | |
| John V. Priestley | grad student | Oxford | |
| Michael V. Sofroniew | grad student | Johns Hopkins, McGill University | |
| Morgan Foret | grad student | 2015- | McGill |
| Tak Pan Wong | grad student | 1995-2001 | McGill |
| Maria T. Ferretti | grad student | 2012 | McGill |
| Edward Nesbitt Wilson | grad student | 2011-2016 | McGill University School of Medicine |
| Lindsay A. Welikovitch | grad student | 2014-2020 | McGill |
| Joshua Emmerson | grad student | 2017-2023 | McGill |
| Alfredo Ribeiro-da-Silva | post-doc | McGill | |
| Valentina Echeverria Moran | post-doc | 2001-2003 | McGill |
| Valentina Echeverria Moran | post-doc | 2001-2003 | McGill University School of Medicine |
| Sonia Do Carmo | research scientist | 2010- | McGill |
Publications
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| Emmerson JT, Do Carmo S, Liu Y, et al. (2023) Progressive human-like tauopathy with downstream neurodegeneration and neurovascular compromise in a transgenic rat model. Neurobiology of Disease. 106227 |
| Dalmasso MC, Arán M, Galeano P, et al. (2023) Nicotinamide as potential biomarker for Alzheimer's disease: A translational study based on metabolomics. Frontiers in Molecular Biosciences. 9: 1067296 |
| Pascoal TA, Chamoun M, Lax E, et al. (2022) Author Correction: [C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease. Nature Communications. 13: 5833 |
| Orciani C, Hall H, Pentz R, et al. (2022) Long-term nucleus basalis cholinergic depletion induces attentional deficits and impacts cortical neurons and BDNF levels without affecting the NGF synthesis. Journal of Neurochemistry |
| Pascoal TA, Chamoun M, Lax E, et al. (2022) [C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer's disease. Nature Communications. 13: 4171 |
| Flores-Aguilar L, Hall H, Orciani C, et al. (2022) Early loss of locus coeruleus innervation promotes cognitive and neuropathological changes before amyloid plaque deposition in a transgenic rat model of Alzheimer's disease. Neuropathology and Applied Neurobiology. e12835 |
| Wong C, Barkai O, Wang F, et al. (2022) mTORC2 mediates structural plasticity in distal nociceptive endings that contributes to pain hypersensitivity following inflammation. The Journal of Clinical Investigation |
| Do Carmo S, Kannel B, Cuello AC. (2021) The Nerve Growth Factor Metabolic Pathway Dysregulation as Cause of Alzheimer's Cholinergic Atrophy. Cells. 11 |
| Do Carmo S, Spillantini MG, Cuello AC. (2021) Editorial: Tau Pathology in Neurological Disorders. Frontiers in Neurology. 12: 754669 |
| Do Carmo S, Kannel B, Cuello AC. (2021) Nerve Growth Factor Compromise in Down Syndrome. Frontiers in Aging Neuroscience. 13: 719507 |