Sheila M. Fleming, Ph.D.

Affiliations: 
Arizona State University, Tempe, AZ, United States 
Area:
Neurobiology of Chronic Stress
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"Sheila Fleming"
Mean distance: 15.76 (cluster 19)
 
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Cheryl D. Conrad grad student 2001 Arizona State
 (Intervention effects in a progressive degeneration model of Parkinson's disease.)
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Publications

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Peng Y, Liou B, Lin Y, et al. (2023) iPSC-derived neural precursor cells engineering recovers acid β-glucosidase deficiency and diminishes α-synuclein and neuropathology. Molecular Therapy. Methods & Clinical Development. 29: 185-201
Simons E, Fleming SM. (2023) Role of rodent models in advancing precision medicine for Parkinson's disease. Handbook of Clinical Neurology. 193: 3-16
Fleming SM, Davis A, Simons E. (2021) Targeting alpha-synuclein via the immune system in Parkinson's disease: Current vaccine therapies. Neuropharmacology. 202: 108870
Torres ERS, Stanojlovic M, Zelikowsky M, et al. (2021) Alpha-synuclein pathology, microgliosis, and parvalbumin neuron loss in the amygdala associated with enhanced fear in the Thy1-aSyn model of Parkinson's disease. Neurobiology of Disease. 158: 105478
Gezer AO, Kochmanski J, VanOeveren SE, et al. (2020) Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits. Neurobiology of Disease. 104947
Froula JM, Castellana-Cruz M, Anabtawi NM, et al. (2020) Correction: Defining α-synuclein species responsible for Parkinson's disease phenotypes in mice. The Journal of Biological Chemistry. 295: 1142
Neal ML, Fleming SM, Budge KM, et al. (2020) Pharmacological inhibition of CSF1R by GW2580 reduces microglial proliferation and is protective against neuroinflammation and dopaminergic neurodegeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 1679-1694
Patterson JR, Duffy MF, Kemp CJ, et al. (2019) Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils. Neurobiology of Disease. 104525
Froula JM, Castellana-Cruz M, Anabtawi NM, et al. (2019) Defining α-synuclein species responsible for Parkinson disease phenotypes in mice. The Journal of Biological Chemistry
Colter BT, Garber HF, Fleming SM, et al. (2018) Ahr and Cyp1a2 genotypes both affect susceptibility to motor deficits following gestational and lactational exposure to polychlorinated biphenyls. Neurotoxicology
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