Kelly N. Nobles, Ph.D.

Biochemistry Duke University, Durham, NC 
G protein-coupled receptors
"Kelly Nobles"
Mean distance: 15.45 (cluster 11)


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Robert J. Lefkowitz grad student 2010 Duke
 (Phosphorylation bar codes induce distinct conformations and functionalities of beta-arrestin.)
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Nobles KN, Xiao K, Ahn S, et al. (2011) Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin. Science Signaling. 4: ra51
Nelson CD, Kovacs JJ, Nobles KN, et al. (2008) Beta-arrestin scaffolding of phosphatidylinositol 4-phosphate 5-kinase Ialpha promotes agonist-stimulated sequestration of the beta2-adrenergic receptor. The Journal of Biological Chemistry. 283: 21093-101
Nobles KN, Guan Z, Xiao K, et al. (2007) The active conformation of beta-arrestin1: direct evidence for the phosphate sensor in the N-domain and conformational differences in the active states of beta-arrestins1 and -2. The Journal of Biological Chemistry. 282: 21370-81
Xiao K, Shenoy SK, Nobles K, et al. (2004) Activation-dependent conformational changes in {beta}-arrestin 2. The Journal of Biological Chemistry. 279: 55744-53
Nobles KN, Yarian CS, Liu G, et al. (2002) Highly conserved modified nucleosides influence Mg2+-dependent tRNA folding. Nucleic Acids Research. 30: 4751-60
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