James S. Swaney, Ph.D.

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Pharmacology
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"James Swaney"
Mean distance: 19.23 (cluster 11)
 

Parents

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Paul A. Insel grad student 2005 UCSD
 (Anti-fibrotic effects of adenylyl cyclase in the heart: Implications for connective tissue remodeling by cardiac fibroblasts.)
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Publications

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Swaney JS, Patel HH, Yokoyama U, et al. (2007) Adenylyl cyclase activity and function are decreased in rat cardiac fibroblasts after myocardial infarction American Journal of Physiology - Heart and Circulatory Physiology. 293: H3216-H3220
Patel HH, Zhang S, Murray F, et al. (2007) Increased smooth muscle cell expression of caveolin-1 and caveolae contribute to the pathophysiology of idiopathic pulmonary arterial hypertension Faseb Journal. 21: 2970-2979
Head BP, Patel HH, Roth DM, et al. (2006) Microtubules and actin microfilaments regulate lipid raft/caveolae localization of adenylyl cyclase signaling components. The Journal of Biological Chemistry. 281: 26391-9
Swaney JS, Patel HH, Yokoyama U, et al. (2006) Focal adhesions in (myo)fibroblasts scaffold adenylyl cyclase with phosphorylated caveolin. The Journal of Biological Chemistry. 281: 17173-9
Insel PA, Head BP, Patel HH, et al. (2005) Compartmentation of G-protein-coupled receptors and their signalling components in lipid rafts and caveolae. Biochemical Society Transactions. 33: 1131-4
Insel PA, Head BP, Ostrom RS, et al. (2005) Caveolae and lipid rafts: G protein-coupled receptor signaling microdomains in cardiac myocytes. Annals of the New York Academy of Sciences. 1047: 166-72
Swaney JS, Roth DM, Olson ER, et al. (2005) Inhibition of cardiac myofibroblast formation and collagen synthesis by activation and overexpression of adenylyl cyclase. Proceedings of the National Academy of Sciences of the United States of America. 102: 437-42
Roth DM, Drumm JD, Bhargava V, et al. (2003) Cardiac-directed expression of adenylyl cyclase and heart rate regulation. Basic Research in Cardiology. 98: 380-7
Ostrom RS, Naugle JE, Hase M, et al. (2003) Angiotensin II enhances adenylyl cyclase signaling via Ca2+/calmodulin. Gq-Gs cross-talk regulates collagen production in cardiac fibroblasts. The Journal of Biological Chemistry. 278: 24461-8
Roth DM, Bayat H, Drumm JD, et al. (2002) Adenylyl cyclase increases survival in cardiomyopathy. Circulation. 105: 1989-94
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