Charles D. Cook, Ph.D.

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
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"Charles Cook"
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Mitchell J. Picker grad student 2000 UNC Chapel Hill
 (Modulatory actions of dopamine D2-like agonists on the effects of mu and kappa opioids.)
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Publications

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Selley DE, Herbert JT, Morgan D, et al. (2003) Effect of strain and sex on mu opioid receptor-mediated G-protein activation in rat brain. Brain Research Bulletin. 60: 201-8
Terner JM, Barrett AC, Cook CD, et al. (2003) Sex differences in (-)-pentazocine antinociception: comparison to morphine and spiradoline in four rat strains using a thermal nociceptive assay. Behavioural Pharmacology. 14: 77-85
Barrett AC, Cook CD, Terner JM, et al. (2002) Sex and rat strain determine sensitivity to kappa opioid-induced antinociception. Psychopharmacology. 160: 170-81
Barrett AC, Cook CD, Terner JM, et al. (2001) Importance of sex and relative efficacy at the mu opioid receptor in the development of tolerance and cross-tolerance to the antinociceptive effects of opioids. Psychopharmacology. 158: 154-64
Cook CD, Barrett AC, Syvanthong C, et al. (2000) The dopamine D3/2 agonist 7-OH-DPAT attenuates the development of morphine tolerance but not physical dependence in rats. Psychopharmacology. 152: 93-104
Cook CD, Barrett AC, Syvanthong C, et al. (2000) Modulatory effects of dopamine D3/2 agonists on kappa opioid-induced antinociception and diuresis in the rat. Psychopharmacology. 152: 14-23
Cook CD, Barrett AC, Roach EL, et al. (2000) Sex-related differences in the antinociceptive effects of opioids: importance of rat genotype, nociceptive stimulus intensity, and efficacy at the mu opioid receptor. Psychopharmacology. 150: 430-42
Cook CD, Rodefer JS, Picker MJ. (1999) Selective attenuation of the antinociceptive effects of mu opioids by the putative dopamine D3 agonist 7-OH-DPAT. Psychopharmacology. 144: 239-47
Morgan D, Cook CD, Picker MJ. (1999) Sensitivity to the discriminative stimulus and antinociceptive effects of mu opioids: role of strain of rat, stimulus intensity, and intrinsic efficacy at the mu opioid receptor. The Journal of Pharmacology and Experimental Therapeutics. 289: 965-75
Morgan D, Cook CD, Smith MA, et al. (1999) An examination of the interactions between the antinociceptive effects of morphine and various mu-opioids: the role of intrinsic efficacy and stimulus intensity. Anesthesia and Analgesia. 88: 407-13
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