Christopher L. Frank, Ph.D.

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
mechanisms of Alzheimer's, neuronal migration and positioning
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"Christopher Frank"
Mean distance: 16.18 (cluster 6)
 

Parents

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Li-Huei Tsai grad student 2008 Harvard
 (Regulated ATF4 persistence in cell cycle control and neurogenesis.)
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Publications

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Frank CL, Liu F, Wijayatunge R, et al. (2015) Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum. Nature Neuroscience. 18: 647-56
Wijayatunge R, Chen LF, Cha YM, et al. (2014) The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival. Molecular and Cellular Neurosciences. 61: 187-200
Frank CL, Ge X, Xie Z, et al. (2010) Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis. The Journal of Biological Chemistry. 285: 33324-37
Buchman JJ, Tseng HC, Zhou Y, et al. (2010) Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex. Neuron. 66: 386-402
Ge X, Frank CL, Calderon de Anda F, et al. (2010) Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis. Neuron. 65: 191-203
Frank CL, Tsai LH. (2009) Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity. Neuron. 62: 312-26
Mao Y, Ge X, Frank CL, et al. (2009) Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell. 136: 1017-31
Kim D, Frank CL, Dobbin MM, et al. (2008) Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity. Neuron. 60: 803-17
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