Bryan H. Chang, Ph.D.

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Chemical biology
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"Bryan Chang"
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Stuart L. Schreiber grad student 2010 Harvard
 (An unbiased, family-wide investigation of PDZ domain specificity.)
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Publications

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Gujral TS, Karp ES, Chan M, et al. (2013) Family-wide investigation of PDZ domain-mediated protein-protein interactions implicates β-catenin in maintaining the integrity of tight junctions. Chemistry & Biology. 20: 816-27
Chang BH, Gujral TS, Karp ES, et al. (2011) A systematic family-wide investigation reveals that ~30% of mammalian PDZ domains engage in PDZ-PDZ interactions. Chemistry & Biology. 18: 1143-52
Kaushansky A, Allen JE, Gordus A, et al. (2010) Quantifying protein-protein interactions in high throughput using protein domain microarrays. Nature Protocols. 5: 773-90
Gordus A, Krall JA, Beyer EM, et al. (2009) Linear combinations of docking affinities explain quantitative differences in RTK signaling. Molecular Systems Biology. 5: 235
Chen JR, Chang BH, Allen JE, et al. (2008) Predicting PDZ domain-peptide interactions from primary sequences. Nature Biotechnology. 26: 1041-5
Kaushansky A, Gordus A, Chang B, et al. (2008) A quantitative study of the recruitment potential of all intracellular tyrosine residues on EGFR, FGFR1 and IGF1R. Molecular Biosystems. 4: 643-53
Chen JR, Chang BH, Allen JE, et al. (2008) Predicting PDZ domain-peptide interactions from primary sequences (Nature Biotechnology (2008) 26, (1041-1045)) Nature Biotechnology. 26: 1193
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