Joshua W. Mugford, Ph.D.

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
sonic hedgehog, patterning, nervous system
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"Joshua Mugford"
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Parents

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Andrew P. McMahon grad student 2008 Harvard
 (The molecular specification and cellular origins of the mammalian metanephric kidney.)
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Publications

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Crowley JJ, Collins AL, Lee RJ, et al. (2015) Disruption of the microRNA 137 primary transcript results in early embryonic lethality in mice. Biological Psychiatry. 77: e5-7
Kobayashi A, Mugford JW, Krautzberger AM, et al. (2014) Identification of a multipotent self-renewing stromal progenitor population during mammalian kidney organogenesis. Stem Cell Reports. 3: 650-62
Williams RL, Starmer J, Mugford JW, et al. (2014) FourSig: A method for determining chromosomal interactions in 4C-Seq data Nucleic Acids Research. 42: e68
Mugford JW, Starmer J, Williams RL, et al. (2014) Evidence for local regulatory control of escape from imprinted X chromosome inactivation Genetics. 197: 715-723
Calabrese JM, Sun W, Song L, et al. (2012) Site-specific silencing of regulatory elements as a mechanism of x inactivation Cell. 151: 951-963
Fedoriw A, Mugford J, Magnuson T. (2012) Genomic imprinting and epigenetic control of development. Cold Spring Harbor Perspectives in Biology. 4: a008136
Mugford JW, Yee D, Magnuson T. (2012) Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation Development (Cambridge). 139: 2130-2138
Mugford JW, Yu J, Kobayashi A, et al. (2009) High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population. Developmental Biology. 333: 312-23
Mugford JW, Sipilä P, McMahon JA, et al. (2008) Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney. Developmental Biology. 324: 88-98
Kobayashi A, Valerius MT, Mugford JW, et al. (2008) Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development. Cell Stem Cell. 3: 169-81
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