John W. Steele
Affiliations: | University of California, San Diego, La Jolla, CA |
Area:
neurobiologyGoogle:
"John Steele"Mean distance: 13.65 (cluster 32) | S | N | B | C | P |
Parents
Sign in to add mentor| Samuel E. Gandy | grad student | 2007-2011 | Mount Sinai | |
| (Molecular Mechanisms of Alzheimer's Cerebral Amyloidosis: A Preclinical Study of Latrepirdine as a Prospective Alzheimer's Therapeutic.) | ||||
| Lawrence SB Goldstein | post-doc | 2014- | ||
| Paul Greengard | post-doc | 2012-2013 | ||
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Publications
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| Inda MC, Joshi S, Wang T, et al. (2020) The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction. Nature Communications. 11: 319 |
| Knight EM, Kim SH, Kottwitz JC, et al. (2016) Effective anti-Alzheimer Aβ therapy involves depletion of specific Aβ oligomer subtypes. Neurology® Neuroimmunology & Neuroinflammation. 3: e237 |
| Klionsky DJ, Abdelmohsen K, Abe A, et al. (2016) Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443 |
| Klionsky DJ, Abdelmohsen K, Abe A, et al. (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222 |
| Brautigam H, Moreno CL, Steele JW, et al. (2015) Physiologically generated presenilin 1 lacking exon 8 fails to rescue brain PS1-/- phenotype and forms complexes with wildtype PS1 and nicastrin. Scientific Reports. 5: 17042 |
| Knight EM, Williams HN, Stevens AC, et al. (2015) Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APP(E693Q) mice through reduction of ganglioside-bound Aβ. Molecular Psychiatry. 20: 109-17 |
| Kim SH, Steele JW, Lee SW, et al. (2014) Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse. Molecular Psychiatry. 19: 1235-42 |
| Wang J, Land D, Ono K, et al. (2014) Molecular topology as novel strategy for discovery of drugs with aβ lowering and anti-aggregation dual activities for Alzheimer's disease. Plos One. 9: e92750 |
| Sproul AA, Jacob S, Pre D, et al. (2014) Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors. Plos One. 9: e84547 |
| Steele JW, Brautigam H, Short JA, et al. (2014) Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model. The Journal of Comparative Neurology. 522: 2319-35 |