Matthew P. Patricelli, Ph.D.

Affiliations: 
2001 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Medicinal Chemistry
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"Matthew Patricelli"
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Benjamin F. Cravatt grad student 2001 Scripps Institute
 (Biochemical and physiological investigations of fatty acid amide hydrolase.)
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Publications

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Kavanagh ME, Horning BD, Khattri R, et al. (2022) Author Correction: Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine. Nature Chemical Biology
Kavanagh ME, Horning BD, Khattri R, et al. (2022) Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine. Nature Chemical Biology
Baltgalvis K, Kikuchi S, Symons K, et al. (2020) Abstract 6411: Discovery of covalent ligands to novel E3 ligases enables bispecific degraders with highly differentiated protein degradation across a broad range of targets Cancer Research. 80: 6411-6411
Janes MR, Zhang J, Li LS, et al. (2018) Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell. 172: 578-589.e17
Okerberg ES, Hainley A, Brown H, et al. (2017) Correction: Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics. Plos One. 12: e0172649
Matthews JM, Bhatt S, Patricelli MP, et al. (2016) Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma. Blood
Okerberg ES, Hainley A, Brown H, et al. (2016) Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics. Plos One. 11: e0152934
Patricelli MP, Janes MR, Li LS, et al. (2016) Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State. Cancer Discovery
Kessler L, Chen J, Guo X, et al. (2016) KO-947, a potent and selective ERK inhibitor with slow dissociation kinetics European Journal of Cancer. 69: S126
Kessler L, Wu T, Grembecka J, et al. (2016) Discovery of novel menin-MLL small molecule inhibitors that display high potency and selectivity in vitro and in vivo European Journal of Cancer. 69
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