Ryan M. Spengler, Ph.D.
Affiliations: | 2013 | Molecular & Cell Biology | University of Iowa, Iowa City, IA |
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"Ryan Spengler"Mean distance: 17811
Parents
Sign in to add mentor| Beverly L. Davidson | grad student | 2013 | University of Iowa | |
| (Mechanisms of microRNA evolution, regulation and function: Computational insight, biological evaluation and practical application.) | ||||
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| Cheng C, Spengler RM, Keiser MS, et al. (2018) The long noncoding RNA NEAT1 is elevated in polyglutamine repeat expansion diseases and protects from disease-gene dependent toxicities. Human Molecular Genetics |
| Giraldez MD, Spengler RM, Etheridge A, et al. (2018) Erratum: Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling. Nature Biotechnology. 36: 899 |
| Giraldez MD, Spengler RM, Etheridge A, et al. (2018) Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling. Nature Biotechnology |
| Suzuki HI, Spengler RM, Grigelioniene G, et al. (2018) Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics. Nature Genetics |
| Ramachandran S, Coffin SL, Tang TY, et al. (2016) Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts. Human Molecular Genetics. 25: 4939-4950 |
| Ramachandran S, Coffin SL, Tang TY, et al. (2016) Cis-Acting Single Nucleotide Polymorphisms Alter MicroRNA-Mediated Regulation of Human Brain-Expressed Transcripts. Human Molecular Genetics |
| Spengler RM, Zhang X, Cheng C, et al. (2016) Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP. Nucleic Acids Research |
| Monteys AM, Wilson MJ, Boudreau RL, et al. (2015) Artificial miRNAs Targeting Mutant Huntingtin Show Preferential Silencing In Vitro and In Vivo. Molecular Therapy. Nucleic Acids. 4: e234 |
| Monteys AM, Spengler RM, Dufour BD, et al. (2014) Single nucleotide seed modification restores in vivo tolerability of a toxic artificial miRNA sequence in the mouse brain. Nucleic Acids Research. 42: 13315-27 |
| Boudreau RL, Jiang P, Gilmore BL, et al. (2014) Transcriptome-wide discovery of microRNA binding sites in human brain. Neuron. 81: 294-305 |