Alessandra Gradi, Ph.D.
Affiliations: | 2000 | McGill University, Montreal, QC, Canada |
Area:
translational controlGoogle:
"Alessandra Gradi"Mean distance: 17.39 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentorNahum Sonenberg | grad student | 2000 | McGill | |
(Translational control in eukaryotes: Discovery of a novel human eukaryotic translation initiation factor and its role in the shutoff of host cell protein synthesis following entero- and rhinovirus infections.) |
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Publications
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Gradi A, Foeger N, Strong R, et al. (2004) Cleavage of eukaryotic translation initiation factor 4GII within foot-and-mouth disease virus-infected cells: identification of the L-protease cleavage site in vitro. Journal of Virology. 78: 3271-8 |
Gradi A, Svitkin YV, Sommergruber W, et al. (2003) Human rhinovirus 2A proteinase cleavage sites in eukaryotic initiation factors (eIF) 4GI and eIF4GII are different. Journal of Virology. 77: 5026-9 |
Liebig HD, Seipelt J, Vassilieva E, et al. (2002) A thermosensitive mutant of HRV2 2A proteinase: evidence for direct cleavage of eIF4GI and eIF4GII. Febs Letters. 523: 53-7 |
Marissen WE, Gradi A, Sonenberg N, et al. (2000) Cleavage of eukaryotic translation initiation factor 4GII correlates with translation inhibition during apoptosis. Cell Death and Differentiation. 7: 1234-43 |
Raught B, Gingras AC, Gygi SP, et al. (2000) Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI. The Embo Journal. 19: 434-44 |
Goldstaub D, Gradi A, Bercovitch Z, et al. (2000) Poliovirus 2A protease induces apoptotic cell death. Molecular and Cellular Biology. 20: 1271-7 |
Svitkin YV, Gradi A, Imataka H, et al. (1999) Eukaryotic initiation factor 4GII (eIF4GII), but not eIF4GI, cleavage correlates with inhibition of host cell protein synthesis after human rhinovirus infection. Journal of Virology. 73: 3467-72 |
Imataka H, Gradi A, Sonenberg N. (1998) A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation. The Embo Journal. 17: 7480-9 |
Gradi A, Svitkin YV, Imataka H, et al. (1998) Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection. Proceedings of the National Academy of Sciences of the United States of America. 95: 11089-94 |
Gradi A, Imataka H, Svitkin YV, et al. (1998) A novel functional human eukaryotic translation initiation factor 4G. Molecular and Cellular Biology. 18: 334-42 |