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Chi-Li Chen, Ph.D.

Affiliations: 
2007 Chemistry and Biochemistry University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Natural Product Synthesis
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"Chi-Li Chen"
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Stephen F. Martin grad student 2007 UT Austin
 (Methodologies for the synthesis of functionalized naphthols and progress toward the total synthesis of vineomycinone boride methyl ester and actinophyllic acid.)

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Publications

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Zhang W, Chen C, He M, et al. (2017) Process Research and Development of TP-808: A Key Intermediate for the Manufacture of Synthetic Tetracyclines Organic Process Research & Development. 21: 377-386
Zhang W, Sun C, Hunt D, et al. (2016) Process Development and Scale-up of Fully Synthetic Tetracycline TP-2758: A Potent Antibacterial Agent with Excellent Oral Bioavailability Organic Process Research & Development. 20: 284-296
Zhang WY, Hogan PC, Chen CL, et al. (2015) Process Research and Development of an Enantiomerically Enriched Allyic Amine, One of the Key Intermediates for the Manufacture of Synthetic Tetracyclines Organic Process Research and Development. 19: 1784-1795
Clark RB, He M, Deng Y, et al. (2013) Synthesis and biological evaluation of 8-aminomethyltetracycline derivatives as novel antibacterial agents. Journal of Medicinal Chemistry. 56: 8112-38
Ronn M, Zhu Z, Hogan PC, et al. (2013) Process R&D of eravacycline: The first fully synthetic fluorocycline in clinical development Organic Process Research and Development. 17: 838-845
Jackson KL, Li W, Chen CL, et al. (2010) Scalable and efficient synthesis of the mycolactone core. Tetrahedron. 66: 2263-2272
Huang X-, Chen C, Lee G-, et al. (2010) Enantioselective Allylation of Ketones Using a SpirocyclicChiral Borate Synfacts. 2010: 327-327
Chen CL, Namba K, Kishi Y. (2009) Attempts to improve the overall stereoselectivity of the Ireland-Claisen rearrangement. Organic Letters. 11: 409-12
Sparks SM, Chen CL, Martin SF. (2007) Tandem Intramolecular Benzyne-Furan Cycloadditions. Total Synthesis of Vineomycinone B(2) Methyl Ester. Tetrahedron. 63: 8619-8635
Martin S, Chen C, Sparks S. (2007) Synthesis of Vineomycinone B2 Methyl Ester Synfacts. 2007: 0236-0236
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