Matthias Brewer, Ph.D.

Affiliations: 
2002 University of Wisconsin, Madison, Madison, WI 
Area:
aspartic protease
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"Matthias Brewer"
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Daniel H. Rich grad student 2002 UW Madison
 (Synthesis of mechanism-based inhibitors of botulinum neurotoxin serotypes A and B.)
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Publications

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Peck AM, Brewer M. (2023) Lewis-Acid-Catalyzed Oxa-Michael Addition to Give α-Diazo-β-alkoxy Carbonyls and Tetrahydro-3-furo[3,4-]pyrazoles. Organic Letters
Li J, Remington JM, Liao C, et al. (2022) GPCR Intracellular Loop Regulation of Beta-Arrestin-Mediated Endosomal Signaling Dynamics. Journal of Molecular Neuroscience : Mn
Fang J, Howard EM, Brewer M. (2020) A conjugate addition approach to diazo-containing scaffolds with β quaternary centers. Angewandte Chemie (International Ed. in English)
Hensinger MJ, Dodge NJ, Brewer M. (2019) Substituted α-Alkylidene Cyclopentenones via the Intramolecular Reaction of Vinyl Cations with Alkenes. Organic Letters
Cleary SE, Hensinger MJ, Qin ZX, et al. (2019) Migratory Aptitudes in Rearrangements of Destabilized Vinyl Cations. The Journal of Organic Chemistry
Liao C, de Molliens MP, Schneebeli ST, et al. (2019) Targeting the PAC1 Receptor for Neurological and Metabolic Disorders. Current Topics in Medicinal Chemistry
Cleary SE, Li X, Yang LC, et al. (2019) Reactivity Profiles of Diazo Amides, Esters, and Ketones in Transition-Metal-Free C-H Insertion Reactions. Journal of the American Chemical Society
Fang J, Brewer M. (2018) Intramolecular Vinylation of Aryl Rings by Vinyl Cations. Organic Letters
Dhakal R, Ivancic M, Brewer M. (2018) Two-Step Sequence of Cycloadditions Gives Structurally Complex Tetracyclic 1,2,3,4-Tetrahydrocinnoline Products. The Journal of Organic Chemistry
Cleary SE, Hensinger MJ, Brewer M. (2017) Remote C-H insertion of vinyl cations leading to cyclopentenones. Chemical Science. 8: 6810-6814
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