☰ Chemistry Tree

Daniel H. Rich

Affiliations:

University of Wisconsin, Madison, Madison, WI

Area:

aspartic protease

Website:

http://www.acsmedchem.org/rich.html

Google:

Bio:

ACS Medicinal Chemistry Hall of Fame, 1992

Mean distance: 7.54

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Parents

Wayland E. Noland	research assistant	1964	UMN
Alfred T. Blomquist	grad student	1968	Cornell
Vincent du Vigneaud	post-doc	1969	Cornell
William Summer Johnson	post-doc	1970	Stanford

Children

Ming Kuan Hu	grad student	1990-1994	UW Madison
James W. Janetka	grad student	1990-1996	UW Madison
Suzanne S Stokes	grad student	1994-1999	UW Madison
Amy M. Elder	grad student	2000	UW Madison
Christopher W. West	grad student	2000	UW Madison
Stacy J. Keding	grad student	2001	UW Madison
Matthias Brewer	grad student	2002	UW Madison
Matthew G. Bursavich	grad student	2002	UW Madison
Chanokporn Sukonpan	grad student	2002	UW Madison
Matthias Brewer	grad student	1997-2002	UW Madison
Neerav M. Shah	grad student	2003	UW Madison

Collaborators

BETA: Related publications

Publications

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Johnson EC, Malito E, Shen Y, et al. (2007) Modular total chemical synthesis of a human immunodeficiency virus type 1 protease. Journal of the American Chemical Society. 129: 11480-90
Haug BE, Brewer M, Rich DH. (2005) Facile degradative lactonization of Gln-Arg and Gln-Phe hydroxyethylene dipeptide derivatives. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 77-83
Haug BE, Rich DH. (2004) Synthesis of a Gln-Phe hydroxy-ethylene dipeptide isostere. Organic Letters. 6: 4783-6
Brewer M, James CA, Rich DH. (2004) Synthesis of a tripeptide derivative containing the gln-arg hydroxyethylene dipeptide isostere. Organic Letters. 6: 4779-82
Sukonpan C, Oost T, Goodnough M, et al. (2004) Synthesis of substrates and inhibitors of botulinum neurotoxin type A metalloprotease. The Journal of Peptide Research : Official Journal of the American Peptide Society. 63: 181-93
Oost T, Sukonpan C, Brewer M, et al. (2003) Design and synthesis of substrate-based inhibitors of botulinum neurotoxin type B metalloprotease. Biopolymers. 71: 602-19
Estiarte MA, Rich DH. (2003) Peptidomimetics for Drug Design Burger's Medicinal Chemistry and Drug Discovery. 633-685
Rich DH, Bursavich MG, Estiarte MA. (2002) Discovery of nonpeptide, peptidomimetic peptidase inhibitors that target alternate enzyme active site conformations. Biopolymers. 66: 115-25
Brewer M, Oost T, Sukonpan C, et al. (2002) Sequencing hydroxyethylamine-containing peptides via Edman degradation. Organic Letters. 4: 3469-72
Bursavich MG, Rich DH. (2002) Designing non-peptide peptidomimetics in the 21st century: inhibitors targeting conformational ensembles. Journal of Medicinal Chemistry. 45: 541-58

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