Michael S. Lopez, Ph.D.
Affiliations: | 2013 | Chemistry and Chemical Biology | University of California, San Francisco, San Francisco, CA |
Area:
signal transduction pathways in cells and whole organismsGoogle:
"Michael Lopez"Mean distance: 8.45 | S | N | B | C | P |
Parents
Sign in to add mentor| Kevan Michael Shokat | grad student | 2008-2013 | UCSF | |
| (The design and development of new inhibitor scaffolds that broaden the scope of analog-sensitive kinase technology.) | ||||
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Publications
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| Rutaganira FU, Barks J, Dhason MS, et al. (2017) Inhibition of calcium dependent protein kinase 1 (CDPK1) by pyrazolopyrimidine analogs decreases establishment and reoccurrence of central nervous system disease by Toxoplasma gondii. Journal of Medicinal Chemistry |
| Warkentin AA, Lopez MS, Lasater EA, et al. (2014) Overcoming myelosuppression due to synthetic lethal toxicity for FLT3-targeted acute myeloid leukemia therapy. Elife. 3 |
| Lopez MS, Kliegman JI, Shokat KM. (2014) The logic and design of analog-sensitive kinases and their small molecule inhibitors. Methods in Enzymology. 548: 189-213 |
| Parker N, Falk H, Singh D, et al. (2014) Responses to glial cell line-derived neurotrophic factor change in mice as spermatogonial stem cells form progenitor spermatogonia which replicate and give rise to more differentiated progeny. Biology of Reproduction. 91: 92 |
| Warkentin AA, Lopez MS, Lasater EA, et al. (2014) Author response: Overcoming myelosuppression due to synthetic lethal toxicity for FLT3-targeted acute myeloid leukemia therapy Elife |
| Lopez MS, Choy JW, Peters U, et al. (2013) Staurosporine-derived inhibitors broaden the scope of analog-sensitive kinase technology. Journal of the American Chemical Society. 135: 18153-9 |
| Zhang C, Lopez MS, Dar AC, et al. (2013) Structure-guided inhibitor design expands the scope of analog-sensitive kinase technology. Acs Chemical Biology. 8: 1931-8 |
| Lourido S, Zhang C, Lopez MS, et al. (2013) Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii. Journal of Medicinal Chemistry. 56: 3068-77 |
| Dar AC, Lopez MS, Shokat KM. (2008) Small molecule recognition of c-Src via the Imatinib-binding conformation. Chemistry & Biology. 15: 1015-22 |