Christine B. Yoo, Ph.D.
Affiliations: | 2007 | Biochemistry and Molecular Biology | University of Southern California, Los Angeles, CA, United States |
Area:
DNA methylation, cancer, epigeneticsGoogle:
"Christine Yoo"Mean distance: 14248.8
Parents
Sign in to add mentor| Peter A. Jones | grad student | 2007 | USC | |
| (Use of DNA methylation inhibitors for chemotherapy and chemoprevention of cancer.) | ||||
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Publications
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| Chuang JC, Warner SL, Vollmer D, et al. (2010) S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth. Molecular Cancer Therapeutics. 9: 1443-50 |
| Jeong S, Liang G, Sharma S, et al. (2009) Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Molecular and Cellular Biology. 29: 5366-76 |
| Miranda TB, Cortez CC, Yoo CB, et al. (2009) DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. Molecular Cancer Therapeutics. 8: 1579-88 |
| Aparicio A, North B, Barske L, et al. (2009) LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors. Epigenetics. 4: 176-84 |
| Yoo CB, Chuang JC, Byun HM, et al. (2008) Long-term epigenetic therapy with oral zebularine has minimal side effects and prevents intestinal tumors in mice. Cancer Prevention Research (Philadelphia, Pa.). 1: 233-40 |
| Yoo CB, Valente R, Congiatu C, et al. (2008) Activation of p16 gene silenced by DNA methylation in cancer cells by phosphoramidate derivatives of 2'-deoxyzebularine. Journal of Medicinal Chemistry. 51: 7593-601 |
| Hother C, Cortez C, Miranda T, et al. (2008) 47 Upregulation of the miR-515 cluster in the MCF7 breast cancer cell line by epigenetic therapy Apmis. 116: 437-437 |
| Yoo CB, Jeong S, Egger G, et al. (2007) Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides. Cancer Research. 67: 6400-8 |
| Egger G, Jeong S, Escobar SG, et al. (2006) Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival. Proceedings of the National Academy of Sciences of the United States of America. 103: 14080-5 |
| Yoo CB, Jones PA. (2006) Epigenetic therapy of cancer: past, present and future. Nature Reviews. Drug Discovery. 5: 37-50 |