Peter A. Jones, PhD

Affiliations: 
University of Southern California University of Southern California, Los Angeles, CA, United States 
Area:
DNA methylation, cancer, epigenetics
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Children

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Mark Gonzalgo grad student USC
Matilda F. Chan grad student 2001 USC
Carvell T. Nguyen grad student 2002 USC
Martha M. Pao grad student 2002 USC
Jonathan C. Cheng grad student 2003 USC
Isabel D. Markl grad student 2006 USC
Christine B. Yoo grad student 2007 USC
Jody C. Chuang grad student 2008 USC
Connie C. Cortez grad student 2008 USC
Erika M. Wolff grad student 2009 USC
Shikhar Sharma grad student 2010 USC
Han Han grad student 2013 USC
Sheng-Fang Su grad student 2013 USC

Collaborators

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Yaping Liu collaborator 2011-2014 USC Keck School of Medicine (Computational Biology Tree)
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Publications

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Esteller M, Dawson MA, Kadoch C, et al. (2024) The Epigenetic Hallmarks of Cancer. Cancer Discovery. 14: 1783-1809
Tiedemann RL, Hrit J, Du Q, et al. (2024) UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation. Biorxiv : the Preprint Server For Biology
Thomas SL, Xu TH, Carpenter BL, et al. (2023) DNA strand asymmetry generated by CpG hemimethylation has opposing effects on CTCF binding. Nucleic Acids Research
Li HT, Jang HJ, Rohena-Rivera K, et al. (2023) RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer. Cell Reports. 42: 112016
Zhang L, Li HT, Shereda R, et al. (2022) DNMT and EZH2 inhibitors synergize to activate therapeutic targets in hepatocellular carcinoma. Cancer Letters. 215899
Zhou W, Hinoue T, Barnes B, et al. (2022) DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse. Cell Genomics. 2
Wiseman AK, Tiedemann RL, Fan H, et al. (2022) Chromosome-specific retention of cancer-associated DNA hypermethylation following pharmacological inhibition of DNMT1. Communications Biology. 5: 528
Pappalardi MB, Keenan K, Cockerill M, et al. (2021) Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nature Cancer. 2: 1002-1017
Xu TH, Liu M, Zhou XE, et al. (2020) Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B. Nature
Zhou W, Liang G, Molloy PL, et al. (2020) DNA methylation enables transposable element-driven genome expansion. Proceedings of the National Academy of Sciences of the United States of America
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